Negative / Null Result ReportOpen accessPhysics and Astronomy
Alexandra Moroianu, Shivani Bhandari, Maria R. Drout et al. · 2025 · The Astrophysical Journal Letters
Abstract We report the milliarcsecond localization of a high (∼1379 pc cm −3 ) dispersion measure (DM) repeating fast radio burst (FRB), FRB 20190417A. Combining European VLBI Network detections of five repeat bursts, we confirm the FRB’s host to be a low-metallicity, star-forming dwarf galaxy at z = 0.12817, similar to the hosts of FRB 20121102A, FRB 20190520B, and FRB 20240114A. We also confirm that it is associated with a previously reported persistent radio source (PRS), which is compact on milliarcsecond scales. Visibility-domain model fitting constrains the transverse physical size of th
View details →Negative / Null Result ReportOpen accessPhysics and Astronomy
P. Abratenko, D. Andrade Aldana, Luciano Arellano et al. · 2025 · Nature
Abstract The existence of three distinct neutrino flavours, ν e , ν μ and ν τ , is a central tenet of the Standard Model of particle physics 1,2 . Quantum-mechanical interference can allow a neutrino of one initial flavour to be detected sometime later as a different flavour, a process called neutrino oscillation. Several anomalous observations inconsistent with this three-flavour picture have motivated the hypothesis that an additional neutrino state exists, which does not interact directly with matter, termed as ‘sterile’ neutrino, ν s (refs. 3–9 ). This includes anomalous observations from
View details →Negative / Null Result ReportOpen accessNeuroscience
Tjaša Mlinarič, Arne Van Den Kerchove, Zoe I. Barinaga et al. · 2026 · Scientific Reports
Abstract Alzheimer’s disease (AD) and frontotemporal dementia (FTD) are two major causes of dementia, with overlapping clinical and pathophysiological characteristics. We investigated whether resting-state EEG functional connectivity could distinguish AD, FTD, and healthy controls (HC) using a stacked ensemble learning approach. A publicly available dataset (openneuro.org/datasets/ds004504) was used to extract multiple connectivity metrics across frequency bands. Base classifiers were trained using the Fisher’s Geodesic Minimum Distance to Mean (FgMDM) approach with Euclidean or Riemannian dis
View details →Negative / Null Result ReportOpen accessAgricultural and Biological Sciences
Shrish Singh, V.K. Jain, Hemraj Verma et al. · 2025 · Discover Food
Food consumption depletes natural resources, pollutes ecosystems, and generates waste, significantly impacting sustainability and the environment. Traditional agriculture, reliant on synthetic fertilizers, pesticides, and excessive water…
View details →Negative / Null Result ReportOpen accessEnvironmental Science
Carlos Alberto de Sousa Rodrigues-Filho, Flávia R. C. Costa, Juliana Schietti et al. · 2024 · Global Change Biology
Tropical biodiversity is undergoing unprecedented changes due to the hydrological cycle intensification, characterized by more intense droughts and wet seasons. This raises concerns about the resilience of animal and plant communities to…
View details →Negative / Null Result ReportOpen accessMedicine
Jimmy Chun Yu Louie · 2026 · Critical Reviews in Food Science and Nutrition
The Nova food classification system has become highly influential in nutritional epidemiology, linking negative health outcomes to "ultra-processed foods" based on industrial formulation. It assumes that products made with substances and…
View details →Negative / Null Result ReportOpen accessHealth Professions
Andrew Hughes, Daniel J. Taylor, P D Morris et al. · 2026 · European Heart Journal
Wearable devices are transforming cardiovascular medicine by enabling continuous monitoring of physiologic and behavioural measures outside of traditional clinical settings. Smartwatches and activity trackers, the most widely used wearables, employ motion and biometric sensors to measure physical activity, sleep quality, heart rate, and rhythm. By converting health goals into objective, quantifiable measures, wearable devices empower patients to assume a more active role in their health while providing clinicians with novel opportunities for longitudinal, real-world assessment. Clinical applic
View details →Negative / Null Result ReportOpen accessImmunology and Microbiology
Ioannis Tsomidis, A. Tsakou, Argyro Voumvouraki et al. · 2026 · Biomedicines
Metabolic dysfunction-associated steatotic liver disease (MASLD) is a continuum of hepatic pathological manifestations of the metabolic syndrome. Pathogenesis is not clearly understood despite recent progress, but Kupffer cells and bone marrow-derived macrophages (BMDMs) have a fundamental role. In this review, the multiple pathophysiological aspects of MASLD are presented, including genetics, insulin resistance, lipotoxicity, and inflammation. The participation of innate and adaptive immunity, as well as the implications of the recently described trained immunity, is presented. The interplay
View details →Negative / Null Result ReportOpen accessEngineering
Prabhu Gurunathappa Sheelavantar, Poornachandra Pandit, Shreelaxmi Prashant · 2026 · Scientific Reports
Abstract The need for sustainable, practical alternatives to Portland cement and two-part alkali-activated systems has led to the development of one-part alkali-activated concrete (OPAAC), which efficiently reuses industrial by-products like fly ash and ground granulated blast furnace slag (GGBS). This study evaluates the fresh (workability) and hardened properties (compressive, tensile, and flexural strengths) of FA-GGBS-based OPAAC, along with durability indicators including sorptivity and chloride ion permeability. A performance-based multi-response optimization using a Taguchi L 9 array an
View details →Negative / Null Result ReportOpen accessEngineering
Anass Moukhliss, Abdellatif Rahmouni, Rhali Benamar · 2025 · Scientific Reports
This paper proposes a discrete physical model (DPM) for the transverse free vibrations of non-uniform bi-directional functionally graded (2D-FGM) beams. The material properties vary in both the axial and thickness directions according to exponential laws, and the beam rest on a spatially variable elastic foundation and satisfy general support conditions. In the proposed formulation, the continuous beam is replaced by a multi-degree-of-freedom chain of lumped masses connected by bars and linear rotational and vertical springs. An adaptive discretization strategy is employed to construct consist
View details →Negative / Null Result ReportOpen accessMedicine
Yuanbing Jiang, Wenyue Zheng, Zengjie Xia et al. · 2026 · Proceedings of the National Academy of Sciences
Phosphorylated-tau 217 (pTau217) is currently the most promising blood-based biomarker for accurately detecting Alzheimer’s disease (AD) pathology. However, interference from peripheral tau species in the kidneys or peripheral nerves can…
View details →Negative / Null Result ReportOpen accessComputer Science
Joshua D Wenger, C. Daryl Cameron, Michael Inzlicht · 2026 · Communications Psychology
Recent advances in AI have enabled large language models to produce expressions that seem empathetic to human users, raising scientific and ethical questions about how people perceive and choose between human and AI sources of emotional support. Although an increasing number of studies have examined how people rate empathy generated by AI, little to no work has examined whether people would choose to receive empathy from AI. We conducted four studies investigating whether people prefer to receive empathetic expressions from humans or AI, and how they evaluate these expressions. Across diverse
View details →Negative / Null Result ReportOpen accessEnvironmental Science
Jingjuan Wu, Qi Li, Qi Li et al. · 2026 · Energies
Carbon dioxide replacement represents a promising hydrate development strategy that effectively balances production efficiency and environmental considerations. However, its production efficiency is lower than that of the depressurization strategy. This limitation can be effectively alleviated by coupling carbon dioxide replacement with inhibitor injection. The design and optimization of the temperature–pressure operating window constrain its effective implementation. In the present work, the phase equilibrium conditions of carbon dioxide hydrate and methane hydrate were experimentally investi
View details →Negative / Null Result ReportOpen accessEngineering
Yiting Lei, Yuwei Zhang, Liangbin Zhou et al. · 2025 · Journal of Orthopaedic Translation
models of orthopaedic conditions have yielded valuable insights into disease mechanisms and drug efficacy, only a few discoveries have been successfully translated to clinical practice. Organoids and organs-on-chips (OoCs) are transforming…
View details →Negative / Null Result ReportOpen accessBiochemistry, Genetics and Molecular Biology
Jiahui Lin, Zhongping Mao, Fei Yan · 2026 · Biosensors
Developing an ultrasensitive electrochemiluminescence (ECL) detection platform remains challenging due to the limited enrichment efficiency of ECL emitters and co-reactants at the electrode interface, as well as the insufficient catalytic enhancement of co-reactant conversion. Moreover, simultaneous in situ analyte enrichment and efficient anti-interference capability are often difficult to achieve in a single sensing interface. Herein, a new ECL platform was developed based on nanocatalyst-supported nanochannel-confined surfactant micelle (SM) system, which integrates an enhanced luminol-diss
View details →Negative / Null Result ReportOpen accessPhysics and Astronomy
Asifa Ashraf, M. Yousaf, Chengxun Yuan et al. · 2026 · The European Physical Journal C
Abstract In this draft, we investigate constant redshift function Morris–Thorne-like traversable wormhole (WH) models which described as a relativistic static fluid distribution in Schwarzschild-type coordinates with a topological global monopole charge under the influence of D -dimensional Einstein gravity. In this scenario we consider three distinct shape functions, while matter sector is supported by anisotropic fluid configuration. We show some basic criteria for the viability of all three shape function models, the radial null energy condition is generally violated while tangential compon
View details →Negative / Null Result ReportOpen accessAgricultural and Biological Sciences
Ke Shi, Qing Zheng, Baorong Wang et al. · 2026 · Nature Communications
Abstract Extracellular polymeric substances (EPS) are key microbial residues that contribute to soil organic carbon (SOC) and promote soil aggregation. Yet, their abundance and large-scale controls have only begun to be investigated. We conduct extensive soil sampling across a European transect spanning diverse climates, bedrocks, and land uses. Average soil EPS content is 956 ± 55 µg g -1 soil ( n = 92 sites), with EPS-carbon (EPS-C) contributing 1.6 ± 0.1% to SOC. Bedrock influences EPS content, EPS-C contribution to SOC, and the EPS-C/microbial biomass carbon (MBC) ratio, whereas land use m
View details →Negative / Null Result ReportOpen accessBiochemistry, Genetics and Molecular Biology
Sevgi Kundu, Senem Akkoç, Yalçın Erzurumlu et al. · 2026 · Molecular and Cellular Biochemistry
Abstract Within the scope of this investigation, two novel compounds ( 3a and 3b ) were designed and synthesized in two steps. Compounds 3a and 3b were tested utilizing the MTT study to evaluate their in vitro cytotoxic activity against healthy human embryonic kidney, lung cancer, breast cancer, and human liver cancer cell lines. It was determined that compound 3b exhibited high levels of cytotoxic activity against both liver and breast cancer cell lines, with IC 50 values of 10.83 and 11.55 µM, respectively. Also, to elucidate the anticancer mechanism of compounds, pro-apoptotic BAX and BiD ,
View details →Negative / Null Result ReportOpen accessBusiness, Management and Accounting
Sad Abu alim, Marwan Mansour · 2026 · Sustainability
FinTech adoption is increasingly viewed as a catalyst for sustainable finance, yet empirical evidence on how and under what conditions it enhances environmental, social, and governance (ESG) performance remains mixed, particularly in emerging economies. This study examines the relationship between FinTech adoption and ESG performance in MENA banks, explicitly modeling corruption risk as an internal governance transmission channel. Using a panel of 152 listed banks across 11 MENA countries over the period 2013–2023 and a novel bank-level FinTech Adoption Index constructed through textual analys
View details →Negative / Null Result ReportOpen accessEconomics, Econometrics and Finance
Jessica Coria, Jūratė Jaraitė · 2025 · Research Policy
This paper examines whether the EU Emissions Trading Scheme (EU ETS) and innovation subsidies interact to enhance green innovation at the firm level. Using staggered difference-in-differences and matched samples, we find no evidence of synergetic effects: firms subject to both the EU ETS and innovation subsidies do not outperform those subject only to subsidies in terms of green patenting outcomes. By contrast, subsidies alone have a clear positive impact on green innovation. Firms receiving subsidies generate more green patents, receive more citations, and develop technologies with greater te
View details →Negative / Null Result ReportOpen accessDecision Sciences
Giuseppe Russo, Manoel Horta Ribeiro, Tim R. Davidson et al. · 2025 · Proceedings of the ACM on Human-Computer Interaction
Journals and conferences worry that peer reviews assisted by artificial intelligence (AI), in particular, large language models (LLMs), may negatively influence the validity and fairness of the peer-review system, a cornerstone of modern…
View details →Negative / Null Result ReportOpen accessBiochemistry, Genetics and Molecular Biology
Lei Li, Hongchao Huang, Yin He et al. · 2025 · Military Medical Research
Sepsis is a dysregulated host response to infection that frequently results in fatal multiple organ dysfunction. Despite advances in clinical identification and management, both its incidence and mortality have remained persistently high. Emerging evidence indicates that cell-free DNA (cfDNA), as a novel biomarker and molecular therapeutic target, holds promise for improving the clinical management of sepsis. cfDNA refers to DNA fragments present in body fluids, including naked DNA, membrane-coated DNA, nucleosomes, and neutrophil extracellular traps (NETs). cfDNA is released from host cells o
View details →Negative / Null Result ReportOpen accessDentistry
Guowu Gan, Ruonan Chen, Peining Zheng et al. · 2026 · Frontiers in Cellular and Infection Microbiology
The oral-gut axis represents a critical bidirectional pathway linking oral microbiota to systemic health. Dysbiosis of the oral microbiome, driven by pathogens like Porphyromonas gingivalis, Fusobacterium nucleatum, Streptococcus species, and Helicobacter pylori, disrupts gut ecology via direct translocation, metabolite signaling (e.g., TMAO, SCFAs), and immune crosstalk (e.g., Th17). This leads to gut barrier dysfunction, systemic inflammation, and metabolic disturbances, contributing to diverse diseases beyond the oral cavity. Evidence supports causal links with conditions including rheumato
View details →Negative / Null Result ReportOpen accessBiochemistry, Genetics and Molecular Biology
Tahrim Ramzan, Muhammad Shahbaz, Farooq Ahmad et al. · 2026 · New Zealand Journal of Crop and Horticultural Science
Salinity stress is a major abiotic factor that inhibits plant growth and yield. This study's objective was to evaluate how foliar applications of melatonin and ascorbic acid affected canola varieties under salt stress. The treatments of…
View details →Negative / Null Result ReportOpen accessComputer Science
Ali Raza, Fareeha Hanif, Heba Abdelgader Mohammed · 2026 · Scientific Reports
Lung cancer remains one of the leading causes of cancer-related mortality worldwide, and accurate early diagnosis plays a critical role in improving patient survival. In this study, a comparative analysis of multiple lightweight Convolutional Neural Network (CNN) variants is presented for multi-class lung cancer classification using histopathological images. Four CNN architectures were designed to systematically explore the trade-off between model complexity and classification performance. Each variant was trained and evaluated within a unified experimental framework incorporating data augment
View details →Negative / Null Result ReportOpen accessMedicine
Y. Kanemitsu, Yasuhiro Shimizu, Junki Mizusawa et al. · 2026 · Journal of Clinical Oncology
JCOG0603 demonstrated improved disease-free survival (DFS) with adjuvant mFOLFOX6 after hepatectomy compared with hepatectomy alone in colorectal liver-only metastasis (CRLM), but the overall survival (OS) data were immature. Here, we…
View details →Negative / Null Result ReportOpen accessEngineering
Teevrat Garg, Ryan Hanna, Jeff Myers et al. · 2026 · Journal of Environmental Economics and Management
Aligning electric vehicle (EV) charging with periods of abundant clean energy is essential for decarbonizing transportation. In solar-dominated grids, this requires shifting charging to midday hours – when vehicles are typically parked at workplaces. Yet workplace charging networks operate under institutional constraints such as shared infrastructure, bundled parking and charging services, and limited willingness to require drivers to move vehicles, making time-of-day pricing and active management difficult to implement. In a natural field experiment (n = 629 drivers) across a large workplace
View details →Negative / Null Result ReportOpen accessBiochemistry, Genetics and Molecular Biology
Ashley Rich, Ziqi Li, Alessandro De Simone et al. · 2026 · Nature Physics
Amputated salamander limbs or fish fins precisely regenerate to their pre-injury size, providing a paradigm for positional memory. Although this phenomenon has been appreciated for centuries, how position-dependent cues control tissue…
View details →Negative / Null Result ReportOpen accessPsychology
Isaac Davor, Francis Ohene Boateng, Franco Osei-Wusu et al. · 2026 · Cogent Education
This study examines the mediating and moderating role of metacognitive awareness in the relationship between self-regulated learning and mathematics achievement of university students in Ghana. Although self-regulated learning has attracted attention as a predictor of academic performance, few studies have examined how metacognitive awareness interacts with self-regulated learning to influence mathematics achievement in the Ghanaian context. A quantitative cross-sectional design was employed. Data were collected from 315 university students, representing a population of 3,240, using a structur
View details →Negative / Null Result ReportOpen accessAgricultural and Biological Sciences
Mohamed T. El‐Saadony, Ahmed Mohamed Saad, Mahmoud Zaki Sitohy et al. · 2026 · Frontiers in Immunology
Probiotics, defined as living microorganisms, are widely recognized for their ability to positively influence the gut microbiota, an effect increasingly linked to a wide array of health benefits. They are claimed to treat or prevent conditions ranging from infant colic to cardiovascular disease, respiratory infections, and certain cancers. Since the beginning of the 21st century, consumer demand for probiotic-enriched foods has risen significantly, propelled by these health assertions. The consumption of such products has been associated with the alleviation of disorders, including irritable b
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