422 real negative results, null findings, and replication failures · Replication Failure. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
· 2026 · Journal of cellular and molecular medicine
Retraction Z. Li and B. M. Pützer, "Spliceosomal Protein E Regulates Neoplastic Cell Growth by Modulating Expression of Cyclin E/CDK2 and G2/M Checkpoint Proteins," Journal of Cellular and Molecular Medicine 12, no. 6a (2008): 2427-2438.…
View details →Kim JH, Hwang YH, Kang E et al. · 2026 · Kidney research and clinical practice
Background Alport syndrome (AS) is a hereditary kidney disorder characterized by progressive hematuria, proteinuria, and kidney failure, frequently accompanied by hearing loss and ocular abnormalities. Although blockade of the…
View details →Gross AR, Lee H, Chacko N et al. · 2026 · The Cochrane database of systematic reviews
Rationale Botulinum toxin type A (BoNT-A) intramuscular injections are commonly administered for neck pain unresponsive to other therapies, but the benefit-harm profile remains uncertain. Objectives To assess the benefits and harms of…
View details →Neeser HR, Gerwinn T, Forschbach VC et al. · 2026 · Journal of pediatric surgery
Background Children still suffer from substantial pain after laparoscopic surgery. It has been hypothesized that low-pressure pneumoperitoneum reduces postoperative pain after laparoscopic surgery. However, this has not yet been studied in…
View details →Rice WM, Shaw AP, Britt RC et al. · 2026 · Journal of the American College of Surgeons
Background Rising patient volumes and an aging population are leading to difficulties in providing timely surgical intervention in emergency general surgery (EGS). With decreased resilience and greater comorbidity burden, we hypothesized…
View details →Ye J, Hoàng DĐ, Liu X et al. · 2025 · Biochemical and Biophysical Research Communications
Schisandrin B (SchB), a natural lignan with reported organ-protective effects, was hypothesized to ameliorate severe acute pancreatitis (SAP). We investigated the effects of SchB (30 and 60 mg/kg) in a caerulein-induced mouse model of SAP…
View details →Morgan W, Butler J · 2023 · BJPsych open
Aims Women from Black and minority ethnic backgrounds have been shown to experience an increased burden of common postnatal mental health conditions and higher rates of involuntary admissions. However, evidence demonstrates disparities in…
View details →Rana D, DeBaer L, Pourcyrous M · 2025 · Children (Basel, Switzerland)
Background Polysubstance use, particularly combining opioids with stimulants such as cocaine, is rising among individuals with substance use disorders. This practice aims to balance cocaine's stimulant effects with opioids' sedative…
View details →Whitehead NN, Kelly SA, Demes JS et al. · 2023 · Behavioural processes
Locomotor play is vigorous and seemingly purposeless behavior, commonly observed in young mammals. It can be costly in terms of energy expenditure, increased injury risk, and predator exposure. The main hypothesized benefit of locomotor…
View details →Grethen KJ, Gómez Y, Toscano MJ · 2025 · Applied Animal Behaviour Science
As the egg-laying industry transitions from cages to cage-free housing, laying hens are increasingly housed in large groups. Cognitive limitations may impair recognition of conspecifics in such large groups, raising questions on the hens’…
View details →Moyini AAM, Tahir M, Farah M et al. · 2025 · Preprint
Abstract This study explores the moderating role of corporate sustainability disclosure (ESG) in the relationship between board-level committees and firm performance (FP) in Sub-Saharan Africa (SSA). While prior research has extensively…
View details →Jedinger A, Feldhausen M · 2025 · The Journal of social psychology
The study examines the impact of hostile and benevolent sexism on attitudes toward public versus private breastfeeding. According to ambivalent sexism theory, we hypothesized that hostile sexism would result in disapproval of public…
View details →Takagi K, Saito G, Tanaka H et al. · 2025 · ESMO open
Background The REMORA trial demonstrated efficacy and safety of lenvatinib in patients previously treated for advanced thymic carcinoma. However, more data regarding its use in clinical practice are required. Methods This multicenter…
View details →Nagpal S, Nguyen KS, Bertrand S et al. · 2025 · Cancer reports (Hoboken, N.J.)
Background Brain metastases are common in patients with lung and breast cancer and are associated with poor outcomes. While there is some intracranial activity with systemic therapies, most chemotherapies are minimally effective.…
View details →Miller RM, Nworu C, McKee L et al. · 2020 · Applied immunohistochemistry & molecular morphology : AIMM
Ataxia-telangiectasia mutated (ATM), a key activator of DNA damage response mechanisms, represents a potential biomarker for targeted gastric carcinoma therapies. A phase II study (Study 39; NCT01063517) designed to investigate the…
View details →Ajam G, Daryabor G, Jazi NN et al. · 2025 · Preprint
Abstract Viruses are among the most infectious agents thought to contribute to the development of autoimmune disorders. Adenoviruses, in particular, are widely utilized for various applications, including gene therapy, vaccine vectors, and…
View details →Heasley CK, Stefanova V, Funk C et al. · 2025 · Preprint
Background Bifidobacterium longum subspecies infantis ( B. infantis ) abundance in the infant gut may be associated with growth and health outcomes. However, these relationships have not been widely studied in settings where B. infantis is…
View details →Miceli MH, Dalton LM, Pasqualotto AC et al. · 2025 · Open Forum Infectious Diseases
Background Histoplasma urine antigen detection, a valuable diagnostic tool, is often used to monitor response to antifungal therapy, but persistently positive antigen values, even when the infection has resolved, often present a clinical…
View details →Akowundu PK, Salako AO, Akinsete AM et al. · 2025 · BMC pediatrics
Background Sickle cell anaemia (SCA) is a lifelong, chronic haemolytic disorder with episodic vaso-occlusive crises (VOC) and chronic end-organ damage. Red cell dehydration during a VOC changes permeability with loss of potassium and…
View details →Blanco JR, Albendin-Iglesias H, Negredo-Puigmal E et al. · 2025 · PloS one
Introduction Inflammation is linked to multiple health conditions. Emerging evidence suggest it may play a role in the association between social isolation - loneliness and health outcomes. People living with HIV (PLWH) exhibit chronic…
View details →Solanki JD, Shah AP, Lalwani N et al. · 2025 · Journal of family medicine and primary care
Introduction Among type 2 diabetics (T2D), macrovascular complication lower limb Peripheral Arterial Disease (PAD) and microvascular complication Diabetic Peripheral Sensory Neuropathy (DPSN) have scarcely studied concordance and their…
View details →Lin X, Ou J, Wu G et al. · 2025 · Biochemistry and biophysics reports
Introduction Venous malformations are the most common congenital vascular anomaly, accounting for 65 % of all congenital vascular abnormalities. This study aims to investigate the correlation between genetic polymorphisms of MALAT1 and the…
View details →Ma Y, Mayes MD, Guo X et al. · 2024 · Preprint
Abstract Objective This study aimed to examine whether a reported SSc-associated SNP rs2841277 in the PLD4 gene identified in an Asian population was also associated with SSc in US Caucasians. Methods The US Caucasian cohort consisting of…
View details →Velaga SB, Alagorie AR, Nittala MG et al. · 2025 · Ophthalmology science
Purpose To evaluate the change in the area of reticular pseudodrusen (RPD) and choroidal thickness over 2 years in eyes with age-related macular degeneration (AMD). Design Longitudinal cohort study. Subjects The study reviewed 1332 eyes…
View details →Belica I, Blasko F, Sleziak I et al. · 2025 · Biological psychology
Resting heart rate variability (HRV) reflects rhythmic changes in heart rate over time associated with autonomic nervous system (ANS) activity. It has served as a predictor of health and the development of various diseases. Therefore, it…
View details →Mirsharifi MS, Shirdel S, Ghaderi E et al. · 2026 · Reproductive sciences (Thousand Oaks, Calif.)
OBJECTIVE: This study aimed to evaluate the effect of vitamin D supplementation on in vitro fertilization (IVF) outcomes in poor responder women with vitamin D deficiency, focusing on fertilization rates, oocyte quality, and pregnancy…
View details →Gaul C, Ferreira S, Johansen T · 2026 · Headache
Objective Evaluate the efficacy and safety of a novel partial rebreathing device for early treatment of acute attacks of migraine with aura. Background Earlier clinical studies have indicated a potential for CO 2 -enriched gas to be…
View details →Ha SH, Kim S, Lee S et al. · 2026 · Parkinsonism & related disorders
Introduction Approximately one-third of patients with Parkinson's disease (PD) develop dementia, and anticholinergic use has been implicated as a risk factor, particularly with prolonged exposure. This study examined whether short-term…
View details →Burgoyne K, Hargreaves S, Akhter N et al. · 2025 · JCPP advances
Background Parents play a key role in their child's early development but evidence that parental engagement strategies are effective is unclear. The current study evaluated a parent-delivered early language teaching programme that aimed to…
View details →Lan T, Ming J, Liu J et al. · 2026 · Preprint
Objective: Evidence on the stress–fecundability relationship is mixed, and both the population heterogeneity and the effects of moderate stress remain understudied. We aimed to investigate the association of stress with fecundability in…
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