Etirinotecan Pegol (NKTR-102) in Patients With Active Brain Metastases From Lung or Breast Cancer.
Nagpal S; Nguyen KS; Bertrand S; Cunanan KM; Padda SK; Pagtama JY; Tisch AH; Coffey G · 2025 · Cancer reports (Hoboken, N.J.)
WASTE classifies this as Replication Failure · AI classification, approximate
A previously reported effect did not replicate here — verify it holds before you build on it.
Abstract (excerpt)
Background Brain metastases are common in patients with lung and breast cancer and are associated with poor outcomes. While there is some intracranial activity with systemic therapies, most chemotherapies are minimally effective.…
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Metadata source: Europe PMC · DOI 10.1002/cnr2.70330