Negative / Null Result ReportOpen accessMedicine (General)
Mohamed Ibrahim Fathallah Abdelhay, Mohamed Hussein Elgendy, Yasser Ramzy Lasheen · 2017 · International Journal of Physiotherapy
Background: Postural hypnosis can lead to cervical pain or bad cosmetic appearance.There is a lack in the literature supporting the efficacy of spinal mobilization techniques in restoring normal thoracic curvature.Mulligan and Maitland's mobilization were used to improve range of motion and referred pain not to restore normal kyphotic angle. The purpose: this study was conducted to compare the efficacy of Mulligan and Maitland spinal mobilization on a kyphotic angle in postural kyphosis. Subjects: seventy-five male subjects with postural kyphosis their age (17-21) years were included in the st
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Seyed Mohammad Mousavi, Alireza Milajerdi, Memhdi Sshayanfar et al. · 2019 · Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum
Background and Objectives: Limited data are available on the relationship between dietary factors and risk of glioma. The current study was conducted to investigate the association between dietary acid load (DAL) and risk of glioma in Iranian adults. Methods: This case-control study was carried out on 128 patients with glioma and 256 healthy subjects (Matched for age and sex) in Tehran, Iran. A validated detailed food frequency questionnaire (FFQ) was used to assess dietary intakes of the participants. DAL was estimated using the protein to potassium ratio (Pro/K) and Glioma was diagnosed base
View details →Negative / Null Result ReportOpen accessMedicine (General)
ZHAO Guangqiang, NAN Dongqi, YUAN Siqi · 2024 · 陆军军医大学学报
Objective To explore the action mechanism of tauroursodeoxycholic acid (TUDCA) promoting intracellular clearance of Burkholderia pseudomallei (B. pseudomallei) in RAW264.7 macrophages. Methods After TUDCA of different concentrations were used to treat RAW264.7 cells pre-infected with B. pseudomallei for 8 h or not, flow cytometry was applied to detect the apoptosis of the infected and control cells. In addition, another endoplasmic reticulum stress (ERS) inhibitor 4-PBA was used to detect the apoptosis and proliferation of host cells after B. pseudomallei infection with Annexin-V/PI double sta
View details →Negative / Null Result ReportOpen accessMedicine (General)
Nahla Tharwat Moussa Ahmed, Hany Ezzat Obaya, Azza Abd Elaziz Abd Elhadi et al. · 2025 · Вестник восстановительной медицины
INTRODUCTION. The double chin is an excessive accumulation of fat in the pre- and post-platysma that can manifest in various forms and sizes. Thin individuals might manifest a double chin, similar to those who are afflicted by obesity. It may result in a reduction in the definition of the mandible and give the perception of obesity or aging. AIM. To evaluate any effect of High-Intensity Focused Ultrasound (HIFU) on sleep quality measures in obese women with a double chin. MATERIALS AND METHODS. Typically, 60 women aged 35–50 years were selected from AL Qasr-Alaini Hospital and were equally div
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Henneman L, van Asperen CJ, Oosterwijk JC et al. · 2020 · Patient Preference and Adherence
Lidewij Henneman,1 Christi J van Asperen,2 Jan C Oosterwijk,3 Fred H Menko,4 Liesbeth Claassen,5 Daniëlle RM Timmermans5 1Department of Clinical Genetics, Amsterdam UMC, Vrije Universiteit, Amsterdam, the Netherlands; 2Department of Clinical Genetics, Leiden University Medical Center, Leiden, the Netherlands; 3Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands; 4Family Cancer Clinic, Netherlands Cancer Institute, Amsterdam, the Netherlands; 5Department of Public and Occupational Health, Amsterdam UMC, Vrije Universiteit, Amster
View details →Negative / Null Result ReportOpen accessMedicine (General)
Heera Lee, Somyeong Hwa, Sunga Cho et al. · 2024 · Medicina
Background and Objectives : Polydeoxyribonucleotides (PDRN), composed of DNA fragments derived from salmon DNA, is widely recognized for its regenerative properties. It has been extensively used in medical applications, such as dermatology and wound healing, due to its ability to enhance cellular metabolic activity, stimulate angiogenesis, and promote tissue regeneration. In the field of dentistry, PDRN has shown potential in promoting periodontal healing and bone regeneration. This study aims to investigate the effects of PDRN on the morphology, survival, and osteogenic differentiation of gin
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Yonghong Wang, Yonghong Wang, Bei Wu et al. · 2025 · Frontiers in Medicine
ObjectiveAcute liver failure (ALF) is a rare yet serious clinical syndrome. Recent studies have indicated that stem cells can effectively treat this condition. However, the optimal route for stem cell transplantation in the treatment of ALF remains unclear. This study aims to investigate the most effective transplantation route for stem cell therapy in ALF.MethodsHuman umbilical cord mesenchymal stem cells (hUC-MSCs) expressing both luciferase and green fluorescent protein were generated using a lentiviral vector. The hUC-MSCs were transplanted via the tail vein, portal vein, and abdominal cav
View details →Negative / Null Result ReportOpen accessMedicine (General)
Vinod Babu .K, Akshata Akalwadi, Sai Kumar .N et al. · 2015 · International Journal of Physiotherapy
Background: Acupuncture TENS is used to improve pain instead of invasive acupuncture. Acupuncture shown to improve dyspnoea and lung functions in COPD (Chronic Obstructive Pulmonary Disease) patients. The purpose of the study is to determine Short term effectiveness of Acupuncture-TENS in reducing dyspnea and improving lung functions for subjects with moderate COPD. Method: An experimental study design, selected 30 geriatric subjects with COPD randomized 15 subjects into each Study and Control group. Study group received Acu-TENS for 45 minutes for total 5 sessions, while control group receive
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Angelo Mottaran, Amelio Ercolino, Lorenzo Bianchi et al. · 2023 · Medicina
Background and Objectives : The aim of this article is to present a single-surgeon, open retroperitoneal lymph node dissection (RPLND) series for testicular cancer in a high-volume center. Materials and Methods : We reviewed data from patients who underwent RPLND performed by an experienced surgeon at our institution between 2000 and 2019. We evaluated surgical and perioperative outcomes, complications, Recurrence-Free Survival (RFS), Overall Survival (OS), and Cancer-Specific Survival (CSS). Results : RPLND was performed in primary and secondary settings in 21 (32%) and 44 (68%) patients, res
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M.C. Azevedo, E.D.R.P. Velloso, V. Buccheri et al. · 2014 · Brazilian Journal of Medical and Biological Research
In adults with non-promyelocytic acute myeloid leukemia (AML), high-dose cytarabine consolidation therapy has been shown to influence survival in selected patients, although the appropriate doses and schemes have not been defined. We evaluated survival after calculating the actual dose of cytarabine that patients received for consolidation therapy and divided them into 3 groups according to dose. We conducted a single-center, retrospective study involving 311 non-promyelocytic AML patients with a median age of 36 years (16-79 years) who received curative treatment between 1978 and 2007. The 13
View details →Negative / Null Result ReportOpen accessMedicine (General)
Jo Howard, Sophie A. Lee, Baba Inusa et al. · 2019 · Trials
Abstract Design This randomised crossover trial compared nocturnal auto-adjusting continuous positive airway pressure (APAP) and nocturnal oxygen therapy (NOT) in adults and children with sickle cell anaemia, with patient acceptability as the primary outcome. Secondary outcomes included pulmonary physiology (adults), safety, and daily pain during interventions and washout documented using tablet technology. Methods Inclusion criteria were age > 8 years and the ability to use an iPad to collect daily pain data. Trial participation was 4 weeks; week 1 involved baseline data collection and week 3
View details →Negative / Null Result ReportOpen accessMedicine (General)
Rui Ping Peng, Zi Qian Zhu, Hong Yi Shen et al. · 2022 · Frontiers in Medicine
ObjectiveThis study aimed to observe vascular and neuroretinal alterations in people with prediabetes [impaired fasting glucose (IFG) and impaired glucose tolerance (IGT)] and normal glucose metabolism.MethodsA total of 21 patients with prediabetes (42 eyes) and 20 healthy controls (40 eyes) participated in our study. All patients underwent a complete eye examination [including fundus fluorescein angiography (FFA) and optical coherence tomography (OCT)] and a related general examination (complete biochemical analysis, routine blood tests, and glycosylated hemoglobin).ResultsOn FFA, no patients
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F Ansari, L Akbari, SH Kohan · 2021 · Armaghane Danesh Bimonthly Journal
Background & aim: Background and Aim: Among working women, health professionals are more exposed to environmental factors and unfavorable working conditions than working women. A large group of health professionals consists of nurses and operating room staff who provide services in hospitals. For this purpose, the present study was conducted to determine the effect of unfavorable working conditions on the incidence of spontaneous abortion in operating room staff and nurses of teaching hospitals in Isfahan. Methods: This was a retrospective analytical study. The statistical population included
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Osama Ragaa Abdelraouf, Amr Almaz Abdel-aziem · 2021 · Chinese Journal of Traumatology
Purpose: This study evaluated the angular kinematic and moment of the ankle and foot during shod walking and barefoot walking in individuals with unilateral chronic ankle instability (CAI). Methods: Recreational soccer players with unilateral CAI were recruited for this cross sectional study conducted between January and August 2019. A total of 40 participants were screened for eligibility but only 31 met the inclusion criteria based on the methods of Delahunt et al and Gribble et al. Except for 3 participants not attending the evaluation session, 28 participants were finally included. A three
View details →Negative / Null Result ReportOpen accessMedicine (General)
Xu Xiaofeng, Zhan Linsen, Lu Huarong et al. · 2024 · Vojnosanitetski Pregled
Background/Aim. Since finding a safe and efficient strategy of multimodal postoperative analgesia and sedation is particularly critical, it is important that dexmedetomidine (DM) combined with opioid anesthetics can enhance that through a synergistic action. The aim of the study was to assess the effect of butorphanol tartrate (BT) combined with DM on postoperative analgesia. Methods. A total of 100 elderly patients undergoing general anesthesia surgery from January 2019 to June 2022 were selected. The patients were divided into two equal groups – research group (RG) and control group (CG), us
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Seoyoung Wy, Seoyoung Wy, Young Kook Kim et al. · 2022 · Frontiers in Medicine
PurposeTo compare the clinical outcomes of maximum tolerated medical therapy (MTMT) in patients with penetrating keratoplasty (PKP) with those of Ahmed glaucoma valve (AGV) implantation.MethodsThe medical records were retrospectively reviewed in patients who had undergone PKP for bullous keratopathy and were treated with MTMT or AGV implantation for the management of glaucoma. A total of 18 bullous keratopathic patients were investigated between January 2010 and February 2017: 9 patients treated with MTMT and 9 patients treated with AGV implantation. Non-corrected visual acuity (NCVA), intraoc
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Martins MJ, Martins CPMO, Castro-Alves LJ et al. · 2018 · Journal of Pain Research
Marcelo J Martins,1 Caroline Paiva Matos Oliveira Martins,2 Lucas J Castro-Alves,3 Gabriel Nascimento Jesus,4 Guilherme Oliveira Campos,5 Breno Barbosa Cerqueira Sacramento,4 Leonardo Ferrari Borges,6 Carlos Augusto Bastos Mello,6 Rodrigo Leal Alves,5 Norma Sueli Pinheiro Módolo7 1Department of Anesthesiology, São Paulo State University (UNESP), São Paulo, Brazil; 2Department of Anesthesiology at Federal University of Bahia, Bahia, Brazil; 3Department of Anesthesiology, Santo Antonio Hospital, Salvador, Bahia, Brazil; 4Department of Anesthesia, Bahia University of Medicine
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Madeleine M. Southey, Trent Rees, Margaret Rolfe et al. · 2019 · Addiction Science & Clinical Practice
Abstract Background Residential opioid rehabilitation aims to improve the mental health and quality of life of opioid users through abstinence and residential program participation. This study aimed to determine the depression, anxiety, stress and quality of life amongst maintenance to abstinence (MTA) program residents. Secondary study aims were to assess the personal characteristics of MTA clients, addiction and risk taking behaviours, factors associated with program completion, as well as to assess the reliable change in participants’ mental health and quality of life on exit. Methods Retro
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Razieh Hajizadeh, Hashem Piri, Nader Naserpour et al. · 2025 · Acta Medica Iranica
Fatigue decreases muscle strength and functional capacity, disrupting neuromuscular coordination by impairing load control. This negatively impacts the kinetics and kinematics of the ankle, knee, and hip joints, resulting in reduced performance and an increased risk of injury, particularly to the anterior cruciate ligament (ACL). This study aimed to compare the effects of fatigue protocols for lower extremity and core muscles on landing mechanics and performance of female athletes. This study used a cross-sectional, comparative, pretest-posttest design with a control group. A total of 105 fema
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Chiou-Lian Lai, Ching-Kuan Liu, Ruey-Tay Lin et al. · 2007 · Kaohsiung Journal of Medical Sciences
The aim of this study was to clarify whether the apolipoprotein E gene (APOE) is related to ischemic stroke subtypes in Taiwan's Chinese population. Using the classification of Cerebrovascular Diseases III, 143 patients with lacunar infarction, 114 patients with atherothrombotic infarction, and 112 healthy controls were enrolled. APOE genotype was determined using polymerase chain reaction. Regarding the distribution of APOE genotypes, the frequency of ϵ3/ϵ4 genotypes in lacunar patients was significantly different from that in control subjects, by logistic regression, using ϵ3/ϵ3 as a referen
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Olivia Anna Mair, Maren Himmler, Suna Brunnemer et al. · 2022 · Medicina
Background and Objectives : Although urogenital injuries are common in severely injured patients, their diagnosis is often delayed. Predicting genitourinary injuries (GUI), especially in the immediate stages post injury, remains a challenge. This study aims to evaluate and determine positive predictive factors for the presence of GUI in polytrauma patients. Subsequently, these factors shall be used to develop an easy-to-use scoring system, deployable directly in the emergency setting. Materials and Methods : This study evaluates all severely injured patients with an Injury Severity Score (ISS)
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Krdžić Igor, Kenić Marko, Šćepanović Milena et al. · 2020 · Vojnosanitetski Pregled
Background/Aim. In colon and rectal cancer surgery, resection is considered radical when circumferential, proximal and distal resection margins are without the presence of tumor cells. Concept of total mesorectal excision in rectal surgery involves complete removal of the tumor with mesorectal fascia which surrounds lymph nodes, lymphatics and blood vessels. The aim of this study was to determine whether laparoscopic approach provides all parameters of oncological radicality as open surgery of colorectal cancer. Methods. The study included 122 patients with carcinoma of colon and rectum, divid
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Jae-Ik Lee, Dong-Hyun Kim, Hyun-Jin Yoo et al. · 2021 · Diagnostics
This study aimed to validate the accuracy and prediction performance of machine learning (ML), deep learning (DL), and logistic regression methods in the treatment of medial meniscus posterior root tears (MMPRT). From July 2003 to May 2018, 640 patients diagnosed with MMPRT were included. First, the affecting factors for the surgery were evaluated using statistical analysis. Second, AI technology was introduced using X-ray and MRI. Finally, the accuracy and prediction performance were compared between ML&DL and logistic regression methods. Affecting factors of the logistic regression method co
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Michelle de Souza Rangel Machado, Tawana Vicente Bertagnolli, Eduardo Carvalho de Arruda Veiga et al. · 2020 · Clinics
OBJECTIVES: To assess the quality of life of hospitalized pregnant women with preeclampsia (PE), and compare with a group of healthy pregnant women (HP). METHODS: This was an observational cross-sectional study conducted among 58 pregnant women; 28 of them had preeclampsia and 30 were healthy. The WHOQOL-Bref questionnaire, which was divided into four aspects: physical, psychological, social, and environmental, was applied to each subject. RESULTS: A statistically significant difference was observed regarding maternal age (PE 27.8±6.2 x HG 23.0±6.6, p<0.01) and gestational age (PE 224±28.1 x H
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Keowmani T, Lee LWL · 2016 · Patient Preference and Adherence
Thamron Keowmani,1 Lily Wong Lee Lee21Clinical Research Centre, 2Hematology Unit, Queen Elizabeth Hospital, Kota Kinabalu, Sabah, MalaysiaPurpose: To study the validity and reliability of the Malay version of the Specific Thalassemia Quality of Life Instrument (STQOLI) in Sabah’s adult thalassemia patients.Patients and methods: This cross-sectional study was done at Thalassemia Treatment Centre, Queen Elizabeth Hospital in Sabah, Malaysia. Eighty-two adult thalassemia patients who fulfilled the inclusion and exclusion criteria were conveniently selected for participation in the study. Th
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Carlo Biz, Luca Puce, Maamer Slimani et al. · 2022 · Medicina
Background and Objectives: Table tennis represents one of the fastest ball games in the world and, as such, is characterized by unique physiological demands. Despite its popularity, there is a dearth of data related to table-tennis-related risk factors and injuries. Therefore, the present review was conducted to fill in this gap of knowledge. Material and Methods: The present review was designed as a scoping review. Eleven online databases were searched with no language/date limitations. Results: Forty-two investigations were retained in the present review. These studies indicated that tenosyn
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Hiroyuki Masaoka, Keitaro Matsuo, Isao Oze et al. · 2020 · Journal of Epidemiology
Background: The association of alcohol drinking with bladder cancer risk remains unclear in East Asian populations. Aldehyde dehydrogenase 2 (ALDH2) enzyme oxidizes alcohol-metabolized carcinogenic acetaldehyde into acetate. It is well known that the inactive ALDH2 carriers, specific to East Asian populations, have an increased risk of several cancer types because of increased exposure to acetaldehyde after alcohol consumption. The aim of this study was to examine the association between alcohol drinking and bladder cancer risk using data from ten population-based prospective cohort studies in
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Lisa Argnani, Anna Zanetti, Anna Zanetti et al. · 2021 · Frontiers in Medicine
Background: Rheumatoid arthritis (RA) is associated with an increase in cardiovascular (CV) risk. This issue maybe not only explained by a genetic component, as well as by the traditional CV risk factors, but also by an underestimation and undertreatment of concomitant CV comorbidities.Method: This was a retrospective matched-cohort analysis in the Italian RA real-world population based on the healthcare-administrative databases to assess the CV risk factors and incidence of CV events in comparison with the general population. Persistence and adherence to the CV therapy were also evaluated in
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Ana Marija Hosnjak, Martina Smrekar, Sanja Ledinski-Ficko et al. · 2023 · Journal of Health Sciences
Introduction: In times when the term inclusion, rights of patients, and the patient as a subject in health care are used more often, the limited availability of written material or sign language interpreters at health services is still a key barrier to health services for people who are hearing-impaired. The aim of this study is to examine nurses’ knowledge of communication skills with hearing-impaired patients, their preferred methods, and the possibility of using translation services. Methods: The study was cross-sectional, and data were collected in September–October 2019. The study include
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Sepide Ghasemian, Zahra Hojjati Zidashti · 2018 · Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum
Background and Objectives: Iron can play an important role in exercise performance of women. The purpose of the present research was to determine the effects of combined exercise training and Feroglobin supplementation on serum iron and lipid profile in Women with iron deficiency anemia. Methods: In this study, 36 trained females with iron deficiency anemia (mean age, 26.8±6.3 years and body mass index, 19.55±4.4kg/m2) of Lahijan city, were selected as subjects and randomly divided into three groups of supplement+combined training, placebo+combined training, and control. Iron lev
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