Negative / Null Result ReportOpen accessMedicine (General)
Yanyuan Wu, Yedie He, Jun Qi et al. · 2024 · Journal of Men's Health
This study was aimed to retrospectively analyze the potential of non-invasive serum biomarkers in clinically predicting the detrusor underactivity (DU) in benign prostatic hyperplasia (BPH) patients with lower urinary tract symptoms (LUTS) and low prostate volume (PV). The study enrolled 196 patients with BPH and LUTS at our hospital in the period from January 2018 to October 2023. The patients were divided into two groups based on the projected isovolumetric pressure (PIP): the DU and the control groups. The patients included in the study had PV of less than 50 mL. A total of 93 and 103 cases
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Joseph Choi, Rajesh Bhayana, Chenhan D Wang et al. · 2020 · BMJ Open Quality
Ordering and protocolling CT scans after-hours from the emergency department (ED) at our institution previously required discussion between the ED physician and radiology resident, which led to workflow inefficiency. Our intervention consisted of creating an electronic list of CT requests that radiology residents would monitor. Radiology protocolled straightforward requests and contacted the ordering physician for more details when required. We aimed to improve workflow efficiency, increase provider satisfaction and reduce CT turnaround time without significantly affecting CT utilisation. Plan
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Dumitru-Dragos Chitca, Octavian Mihalache, Florin Bobircă et al. · 2026 · Diagnostics
Background : Anastomotic leakage (AL) remains one of the most feared complications after colorectal surgery. This study aimed to identify preoperative risk factors for AL using a five-year dataset from two Romanian surgical clinics. Materials and Methods : A retrospective cohort of 155 patients undergoing colorectal resection with primary anastomosis (105 from “Colentina” Hospital and 50 from “Dr. I. Cantacuzino” Hospital) was analyzed. Preoperative demographic, clinical, and laboratory data were extracted and assessed using univariate and multivariable logistic regression. Statistical analyse
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Oded Hershkovich, Inga Tetroashvili, Adam Lee Goldstein et al. · 2024 · Medicina
Background and Objectives: The incidence of proximal femoral fractures (PFFs) is rising, causing significant morbidity and mortality. Regional anesthesia (RA)’s benefits include the avoidance of intubation and mechanical ventilation, decreased blood loss, and improved analgesia. General anesthesia (GA) offers improved hemodynamic stability. This study examines the in-hospital post-surgical morbidity and mortality seen in PFFs in a cohort of the elderly undergoing GA or RA. Materials and Methods: This is a retrospective cohort study of 319 PFF patients older than 65 years over a single year. Re
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Seyed Hosein Tabatabaei, Seyed Mehdi Kalantar, Mohammad Hasan Akhavan Karbassi et al. · 2021 · Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd
Introduction: Considering the importance of oral health as a part of general health and the role of physicians in community health, the present study was conducted to investigate the relationship between common oral diseases and general body health from the perspective of medical students in Yazd City in 2018. Methods: In this descriptive cross-sectional study, 210 internship and pre-internship students of Shahid Sadoughi University of Medical Sciences in Yazd Cityin 2018 were selected randomly and their knowledge about common oral and dental diseases and its relationship with general body hea
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Erol ŞENTÜRK, Selahattin TUĞRUL, Yavuz Selim YILDIRIM et al. · 2018 · Bezmiâlem Science
Objective:Systemic absorption of steroids is reasonable because of the lipophilic nature of steroids and high vascularity of the middle ear mucosa. To date, however, of the clinical trials designed to investigate this subject, to the best of our knowledge, none has been based on objective methods. This study aims to demonstrate whether the intratympanic administration of dexamethasone has any systemic effects.Methods:Seventeen patients had a total of five sessions of intratympanic dexamethasone treatment scheduled for every other day. The mean fasting blood glucose, serum cortisol, serum adren
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Guo Zheng, Huiling Gao, Zhao Jin et al. · 2026 · Frontiers in Medicine
BackgroundPreservation of ovarian perfusion is a critical consideration during uterine artery embolization (UAE), as inadvertent disruption can reduce ovarian reserve. Given the complex and variable anatomy of ovarian blood supply, this study aimed to characterize its anatomical origins and variations using digital subtraction angiography (DSA) in patients undergoing UAE for cesarean scar pregnancy (CSP).MethodsThis retrospective study included patients with type II or III CSP who underwent first-time UAE at Heibei Maternity Hospital, China, between August 2020 and October 2024. Pre-embolizati
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Maria Aparecida A.O. Serra, PhD, Arlene T. Medeiros, RN, Mateus D. Torres, RN et al. · 2021 · Journal of Taibah University Medical Sciences
الملخص: أهداف البحث: الأعراض الهضمية هي الشكاوى الأكثر شيوعا من قبل المرضى الذين يسعون للحصول على خدمات الرعاية الصحية الأولية. تهدف هذه الدراسة إلى تحديد أعراض الجهاز الهضمي وتحديد ارتباطها بنتائج التنظير المعوي العلوي لدى المرضى الذين عولجوا في مركز التنظير العام في شمال شرق البرازيل. طرق البحث: أجرينا دراسة مقطعية باستخدام بيانات ٧٥١ مريضا يعانون من أعراض الجهاز الهضمي ولديهم حاجة للتنظير المعوي العلوي. حددنا الارتباط بين هذه المتغيرات من خلال اختبار فيشر الدقيق وحسبنا نسبة الاحتمالات. النتائج: أظهرت النتائج أن ٨٣٪ من المرضى يعانون من آلام شرسوفية، ٧٢.٦٪ من الامتلاء بعد الأكل، و٧٢.٣٪ من حرق
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Sacide Karakas, Ayfer Metin Tellioglu, Mehmet Bilgin et al. · 2019 · Eurasian Journal of Medicine
Abstract Objective: Thalassemias major are the most common autosomal recessive disorders; they are characterized by anomalies in the synthesis of the beta chains of hemoglobin and are often associated with varying degrees of craniofacial anomalies. The purpose of this study was to evaluate the craniofacial dimensions of β-thalassemia patients and to identify differences by comparing them to those of a control group. Materials and Methods: The study comprised 43 thalassemia major patients and 26 age- and sex- matched healthy control subjects. Anthropometric measurements were performed in six di
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O.E. Soares, A.A.V. Cruz · 2004 · Brazilian Journal of Medical and Biological Research
The objective of the present study was to describe, for the first time in Brazil, the use by a non-ophthalmologist of a community-based marginal rotation procedure by a posterior approach in the indigenous population from the Upper Rio Negro basin. Seventy-three upper eyelids of 46 Indians (11 males and 35 females) with cicatricial upper eyelid entropion and trichiasis were operated in the Indian communities using a marginal rotational procedure by a posterior approach by a non-ophthalmologist physician who had general surgery experience but only an extremely short period (one week) of ophthal
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Hiroaki Kuroda, Junji Ichinose, Katsuhiro Masago et al. · 2021 · Medicina
Background and Objectives : Lobe-specific nodal dissection (L-SND) is currently acceptable for the dissection of early-stage non-small cell lung cancer (NSCLC) but not for cancers of more advanced clinical stages. We aimed to assess the efficacy of L-SND, compared to systemic nodal dissection (SND). Materials and Methods : We retrospectively collected the clinical data of patients with carcinoembryonic antigen (CEA) abnormality who underwent complete resection of NSCLC via lobectomy or more in addition to either SND or L-SND at two cancer-specific institutions from January 2006 to December 201
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MR Yeganekhah, T Dadkhahe Tehrani, MT Ziyuayinejad · 2012 · Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum
Background and Objectives: Coronary angiography is the golden diagnostic test for coronary heart disease that causes various vascular complications. To prevent these complications, patients are completely restricted in bed. Changing position is considered an alteration in routine care protocols after coronary angiography, improving patients’ comfort and satisfaction that is considered in current studies. The purpose of this study is the comparing different ways of position on vascular complications after coronary angiography. Methods: This clinical trial study was carried out in post angiograp
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Emily Sheppard, MScPT, Michael Smyth, MSc, Todd Dow, BSc et al. · 2020 · Archives of Rehabilitation Research and Clinical Translation
Objective: To assess the effect the Pre-clerkship Residency Exploration Program (PREP) had on student career interest and improving understanding of physical medicine and rehabilitation (PMR). Design: During a 2-week program, students were exposed to a PMR elective, workshop, career presentation, and panel discussion with PMR residents. Interest and understanding were assessed using pre- and postprogram questionnaires. Setting: PREP was held at a Canadian medical school during the summer between the second and third years of undergraduate medical training. Participants: Second-year medical stu
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M.A. Arbex, L.C. Martins, L.A.A. Pereira et al. · 2007 · Brazilian Journal of Medical and Biological Research
Studies of cooking-generated NO2 effects are rare in occupational epidemiology. In the present study, we evaluated the lung function of professional cooks exposed to NO2 in hospital kitchens. We performed spirometry in 37 cooks working in four hospital kitchens and estimated the predicted FVC, FEV1 and FEF25-75, based on age, sex, race, weight, and height, according to Knudson standards. NO2 measurements were obtained for 4 consecutive days during 4 different periods at 20-day intervals in each kitchen. Measurements were performed inside and outside the kitchens, simultaneously using Palm diff
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Fatemeh Zanganeh, Amir Jalali, Hamid Galehdari et al. · 2014 · Iranian South Medical Journal
Background: Cytochrome P450 2E1 (CYP2E1) is a main enzyme which plays a major role in activating and detoxifying many xenobiotics, carcinogens and drugs. Available studies suggest that CYP2E1 single nucleotide polymorphisms (SNPs) are involved in the risk of developing certain cancers after exposure to carcinogens. The purpose of the present study was to assess genotype and allele frequencies of polymorphic CYP2E1*5B in the Iranian population. Material and Methods: This study was performed on 200 healthy individuals (female: 100, male: 100) in medical laboratories of Ahvaz during 2011. The CYP
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Mori N, Kobayashi A, Yokogawa H et al. · 2025 · International Medical Case Reports Journal
Natsuko Mori, Akira Kobayashi, Hideaki Yokogawa, Tomomi Higashide Department of Ophthalmology, Kanazawa University Graduate School of Medical Science, Kanazawa, JapanCorrespondence: Akira Kobayashi, Department of Ophthalmology, Kanazawa University Graduate School of Medical Science, 13-1 Takara-machi, Kanazawa, Ishikawa, 920-8641, Japan, Tel +81-76-265-2403, Fax +81-76-222-9660, Email eyekoba@gmail.comPurpose: To describe two corneal adverse events temporally associated with anti–tumor necrosis factor-α (TNF-α) therapy—one with severe fibrovascular pannus and another with epithelial keratopath
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Mercedes Navarro, Gonzalo Hijos, Carlos Sostres et al. · 2020 · Frontiers in Medicine
Introduction: The fecal immunochemical test (FIT) has been established as a cost-effective test in colon cancer screening programmes. This test could also be helpful in symptomatic patients prior to colonoscopy, but data about diagnostic performance, and accurate cut-off values for these patients are still scarce.Materials and Methods: Prospective study that included consecutive unselected patients with gastrointestinal symptoms referred for colonoscopy between November 2016 and June 2018. We performed a FIT (FOB Gold® test, cut-off 20 micrograms of Hb/gram of feces) prior to colonoscopy and d
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Ravieh Golchoobian, Fatemeh Nabavizadeh, Mehrdad Roghani et al. · 2018 · Acta Medica Iranica
Hepatotoxicity is one of the clinically adverse effects of ecstasy (3, 4-methylenedioxymethamphetamine; MDMA) consumption. The detoxification tissue, liver, plays a central role in maintaining circulating levels of glucose and lipid. Hypoglycemia and hypotriglyceridemia have been reported due to ecstasy abuse. Ghrelin is a 28-amino-acid peptide secreted predominantly from the stomach. It has been demonstrated that ghrelin has hepatoprotective effects and is able to increase blood glucose concentration. In the current study, we explored the effect of hepatotoxic dose of MDMA and therapeutic use
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Weishen WANG, Wenhui LOU, Zhiwei XU et al. · 2023 · Journal of Advanced Research
Introduction: The value of extended lymphadenectomy in pancreatoduodenectomy (PD) has been discussed by five randomized controlled studies. However, the limitations in the studies made their conclusions not sufficiently reliable. Objectives: This multi-center randomized controlled study was designed to clarify the efficacy of extended lymphadenectomy in PD for pancreatic ductal adenocarcinoma (PDAC). Methods: From December 2016 to October 2018, 170 consecutive patients undergoing PD were enrolled and randomized to standard or extended lymphadenectomy for the treatment of PDAC from three high-v
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Yang H, Gao J, Li S et al. · 2021 · International Journal of General Medicine
Hua Yang,1,* Jian Gao,2,* Shuyu Li,1 Huiling Xia,1 Zhangyan Chen,1 Shanzhu Zhu,1 Zhigang Pan1 1Department of General Practice, Zhongshan Hospital of Fudan University, Shanghai, 200030, People’s Republic of China; 2Department of Nutrition, Zhongshan Hospital of Fudan University, Center of Clinical Epidemiology and Evidence-Based Medicine, Fudan University, Shanghai, 200030, People’s Republic of China*These authors contributed equally to this workCorrespondence: Shanzhu Zhu; Zhigang PanDepartment of General Practice, Zhongshan Hospital of Fudan University, No. 180, Road Fenglin, Shan
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Zhaleh Shadman, Nooshin Poorsoltan, Mahdieh Akhoundan et al. · 2014 · Journal of Fasting and Health
The aim of this study was to assess public knowledge about the effects of Ramadan fasting on various aspects of health and its association with fasting decision-making. This cross-sectional study was conducted on 600 subjects. The association between fasting and participants’ knowledge and attitudes toward Ramadan fasting, anthropometric measurements, physical activity, depression, anxiety, stress, dietary intake, and prior history of diseases was evaluated. The results indicated an adverse correlation between negative attitudes towards the effects of Ramadan fasting and adherence to fasting (
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Xiaomin Liang, Qian Wang, Zemao Xing et al. · 2026 · Frontiers in Medicine
ObjectiveAcute ischemic stroke (AIS) is a leading cause of disability and mortality worldwide. Hematocrit (HCT), the proportion of blood volume occupied by red blood cells, has been associated with outcome in AIS patients, but the relationship remains controversial. This study aimed to investigate the association between HCT levels and 3-month adverse outcome in South Korean patients with AIS, with a focus on potential sex differences.MethodsThis secondary analysis utilized data from an existing South Korean prospective cohort study involving 1,896 AIS patients. HCT was assessed both as a cont
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Mohammad-Ali Seif-Rabiei, Mehrdad Hajilooi, Uldoz Roustaei et al. · 2011 · Acta Medica Iranica
There is some evidence indicating the role of Helicobacter pylori infection in pathogenesis of extragastrointestinal diseases including skin, vascular, and autoimmune disorders, as well as some respiratory diseases. The aim of this study was to investigate the association between H. pylori and chronic obstructive pulmonary disease (COPD). In a case-control study, 90 patients with COPD and 90 age- and sex- matched control subjects were included. Serum samples were tested for anti-H. pylori and anti-CagA IgG by ELISA. A physician completed a questionnaire including demographic characteristics, h
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Jiao LI, Qi LI, Shuang CHENG et al. · 2026 · 环境与职业医学
BackgroundGestational weight gain is closely related to maternal and infant health outcomes. Pregnant women are simultaneously exposed to four metals—lithium (Li), vanadium (V), uranium (U), and bismuth (Bi)—through inhalation of fine particulate matter and consumption of contaminated food and water. Existing studies suggest that exposure to these metals may be associated with gestational weight gain. However, no study has yet explored the complex relationships between exposure to mixtures of these four metals and weight gain at different stages of pregnancy.ObjectiveTo investigate the associa
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Hanan Al-Wakeel, Nadia Sewelam, Mohamed Khaled et al. · 2018 · Egyptian Journal of Medical Human Genetics
Background: Many genetic factors, including polymorphisms in the genes regulating blood coagulation and fibrinolysis have been proposed as risk factors for coronary artery disease (CAD). PAI-1 is the chief inhibitor of tissue plasminogen activator and urokinase plasminogen activator. PAI-1 has a crucial role in regulation of fibrinolysis. Aim of the study: Is to investigate the association between Plasminogen activator inhibitor-1 (PAI-1) 4G/5G, PAI-1C/G polymorphisms and CAD. In addition, studying the relation of these polymorphisms to the level of active PAI-1 in Egyptian patients presenting
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Kelly Lim, Meng‐Ni Wu, Wei‐Chia Tsao et al. · 2026 · Kaohsiung Journal of Medical Sciences
ABSTRACT The long‐term cumulative impact of metabolic syndrome (MS) on cognitive decline remains uncertain. This study investigated how changes in MS status over 10 years relate to cognition and whether sex modifies this relationship. A total of 766 participants (mean baseline age: 54 years) from the Kaohsiung Atherosclerosis Longitudinal Study were enrolled. MS was defined using the modified National Cholesterol Education Program Adult Treatment Panel III criteria for Asian populations. Participants were categorized into four groups based on changes in MS status over the 10‐year follow‐up: ne
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Margaret Diana , Deviana Soraya Riu, Fatmawati Madya et al. · 2025 · Obgynia
Objective: This study aimed to investigate the impact of SHS exposure on fetal biometry and umbilical artery flow at 24 – 28 weeks of gestation. Methods: This cross-sectional study included 110 pregnant women, divided into a study group (55 passive) smokers and a control group (55 non-passive smokers). Serum cotinine levels were measured using ELISA. Fetal biometry (biparietal diameter, head circumference, abdominal circumference, and femur length) and umbilical artery flow (pulsatility and resistance indices) were assessed via ultrasound and Doppler ultrasonography. Group comparisons were con
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Wei-Kai Chuang, Skye Hung-Chun Cheng, Chen-Fang Hung et al. · 2022 · Journal of the Formosan Medical Association
Background/purpose: This study aimed to analyze the long-term outcomes of hypofractionated whole-breast irradiation (WBI) (HF-WBI) compared with those of conventionally fractionated WBI (CF-WBI) for early breast cancer treated with breast-conservation surgery (BCS) and adjuvant WBI in Taiwan. Methods: This study included patients treated at our institution between 2012 and 2016. All patients with early breast cancer received BCS (pT1–2, pN0, M0) and adjuvant WBI through one of two treatment schemes. Propensity score matching analysis was conducted to create comparable cohorts. The major result
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Hongseok Yoo, Jimi Oh, Chul Park · 2020 · Military Medical Research
Abstract Background In 2014, an outbreak of adenoviral pneumonia occurred in the Korean military training center. However, there are limited data on the characteristics of the fever and its response to antipyretic therapy in immunocompetent adults with adenovirus-positive community-acquired pneumonia (CAP). Methods The medical records of the patients who were admitted to the Armed Forces Chuncheon Hospital for the treatment of CAP between January 2014 and December 2016 were retrospectively analyzed. The patients were divided into three groups, namely, the adenovirus-positive (Adv) group, the a
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Zhen Yu Jia, Yuan Yuan Jiang, Jung Min Woo et al. · 2018 · Neurointervention
Purpose Wide-neck aneurysms (WNAs) associated with a dilated parent artery (PA) are not uncommon morphological abnormalities and usually cause inappropriate wall apposition and incomplete neck coverage of a tubular stent in stent-assisted coiling of aneurysms. We aimed to introduce a fusiform-shaped stent (FSS) and test its effectiveness in treating intracranial WNAs associated with a dilated PA using a three-dimensional (3D) model. Materials and Methods Two FSS types were designed with the middle one-third segment dilated by 10% (FSS10) and 20% (FSS20) and were compared with the tubular-shape
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