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37 real negative results, null findings, and replication failures in Materials Science · Negative / Null Result Report. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result ReportOpen accessMaterials Science

Fabrication of alginate–gelatin crosslinked hydrogel microcapsules and evaluation of the microstructure and physico-chemical properties

Bapi Sarker, Dimitrios G. Papageorgiou, Raquel Silva et al. · 2013 · Journal of Materials Chemistry B

Microencapsulation of cells by using biodegradable hydrogels offers numerous attractive features for a variety of biomedical applications including tissue engineering. This study highlights the fabrication of microcapsules from an…

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Negative / Null Result ReportMaterials Science

Oxygen Vacancy‐Induced Dielectric Polarization Prevails in the Electromagnetic Wave‐Absorbing Mechanism for Mn‐Based MOFs‐Derived Composites

Yue Liu, Xinfeng Zhou, Zirui Jia et al. · 2022 · Advanced Functional Materials

Abstract Polymeric metal‐organic framework (MOF)‐derived composites are promising functional materials because of their exceptional chemical homogeneity, designable components, and adjustable pore size. The modulation of oxygen and Mn…

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Negative / Null Result ReportOpen accessMaterials Science

Needleless Melt‐Electrospinning of Polypropylene Nanofibres

Jian Fang, Li Zhang, David Sutton et al. · 2012 · Journal of Nanomaterials

Polypropylene (PP) nanofibres have been electrospun from molten PP using a needleless melt‐electrospinning setup containing a rotary metal disc spinneret. The influence of the disc spinneret (e.g., disc material and diameter), operating parameters (e.g., applied voltage, spinning distance), and a cationic surfactant on the fibre formation and average fibre diameter were examined. It was shown that the metal material used for making the disc spinneret had a significant effect on the fibre formation. Although the applied voltage had little effect on the fibre diameter, the spinning distance affe

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Negative / Null Result ReportOpen accessMaterials Science

On the Origin of Surface Traps in Colloidal II–VI Semiconductor Nanocrystals

Arjan J. Houtepen, Zeger Hens, Jonathan S. Owen et al. · 2016 · Chemistry of Materials

One of the greatest challenges in the field of semiconductor nanomaterials is to make trap-free nanocrystalline structures to attain a remarkable improvement of their optoelectronic performances. In semiconductor nanomaterials, a very high…

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Negative / Null Result ReportOpen accessMaterials Science

Amendment of Agricultural Soil with Metal Nanoparticles: Effects on Soil Enzyme Activity and Microbial Community Composition

Bahareh Asadishad, Shawninder Chahal, Ali Akbari et al. · 2018 · Environmental Science & Technology

Several types of engineered nanoparticles (ENPs) are being considered for direct application to soils to reduce the application and degradation of pesticides, provide micronutrients, control pathogens, and increase crop yields. This study…

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Negative / Null Result ReportMaterials Science

Significant Differences in the Hydrolysis Behavior of Amorphous and Crystalline Portions within Microcrystalline Cellulose in Hot-Compressed Water

Yun Yu, Hongwei Wu · 2010 · Industrial & Engineering Chemistry Research

Due to the presence of amorphous structure in microcrystalline cellulose, the reactivity of microcrystalline cellulose exhibits a considerable reduction in the initial stage during hydrolysis in hot-compressed water (HCW). Further analysis…

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Negative / Null Result ReportOpen accessMaterials Science

Poly-3-Hydroxybutyrate Metabolism in the Type II Methanotroph Methylocystis parvus OBBP

Allison J. Pieja, Eric Sundström, Craig S. Criddle · 2011 · Applied and Environmental Microbiology

Differences in carbon assimilation pathways and reducing power requirements among organisms are likely to affect the role of the storage polymer poly-3-hydroxybutyrate (PHB). Previous researchers have demonstrated that PHB functions as a…

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Negative / Null Result ReportOpen accessMaterials Science

Young’s equation revisited

Lasse Makkonen · 2016 · Journal of Physics Condensed Matter

Young's construction for a contact angle at a three-phase intersection forms the basis of all fields of science that involve wetting and capillary action. We find compelling evidence from recent experimental results on the deformation of a soft solid at the contact line, and displacement of an elastic wire immersed in a liquid, that Young's equation can only be interpreted by surface energies, and not as a balance of surface tensions. It follows that the a priori variable in finding equilibrium is not the position of the contact line, but the contact angle. This finding provides the explanatio

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Negative / Null Result ReportMaterials Science

ZnO nanoparticles and root colonization by a beneficial pseudomonad influence essential metal responses in bean (Phaseolus vulgaris)

Christian O. Dimkpa, Trevor Hansen, Jacob Stewart et al. · 2014 · Nanotoxicology

Nanoparticles (NPs) incorporated into commercial products are reactive on plants. Here, the influence of a root-associated bacterium, Pseudomonas chlororaphis O6 (PcO6) on the responses of bean (Phaseolus vulgaris) to commercial ZnO…

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Negative / Null Result ReportOpen accessMaterials Science

Why do we observe significant differences between measured and ‘back-calculated’ properties of natural fibres?

Darshil U. Shah, Ranajit Kumar Nag, Mike Clifford · 2016 · Cellulose

The drive towards sustainability, even in materials technologies, has fuelled an increasing interest in bio-based composites. Cellulosic fibres, such as flax and jute, are being considered as alternatives to technical synthetic fibres, such as glass, as reinforcements in fibre reinforced polymer composites for a wide range of applications. A critical bottleneck in the advancement of plant fibre composites (PFRPs) is our current inability to predict PFRP properties from data on fibre properties. This is highly desirable in the cost- and time-effective development and design of optimised PFRP ma

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Negative / Null Result ReportOpen accessMaterials Science

A randomized study of pegylated liposomal doxorubicin versus continuous-infusion doxorubicin in elderly patients with acute lymphoblastic leukemia: the GRAALL-SA1 study

Mathilde Hunault, T. Leguay, Xavier Thomas et al. · 2010 · Haematologica

BACKGROUND: The prognosis of acute lymphoblastic leukemia in the elderly is poor. The GRAALL-SA1 phase II, randomized trial compared the efficacy and toxicity of pegylated liposomal doxorubicin versus continuous-infusion doxorubicin in…

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Negative / Null Result ReportOpen accessMaterials Science

Regulating nanomedicines: challenges, opportunities, and the path forward

Bharti Mangla, Pankaj Kumar, Shamama Javed et al. · 2025 · Nanomedicine

Over the past decade, nanomedicines have witnessed significant advancements, with various nanocarriers being introduced into clinical practice. Despite this progress, the absence of a well-defined regulatory framework presents major…

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Negative / Null Result ReportOpen accessMaterials Science

Crystallization kinetics of amorphous calcium carbonate in confinement

Jack Cavanaugh, Michael Whittaker, Derk Joester · 2019 · Chemical Science

In situ observation of amorphous calcium carbonate (ACC) confined in ∼500 pL emulsion droplets allows determination of the timing of individual crystal nucleation events. Statistical analysis of events in hundreds of droplets establishes…

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Negative / Null Result ReportOpen accessMaterials Science

Micelle carriers based on dendritic macromolecules containing bis-MPA and glycine for antimalarial drug delivery

Elisabet Martí Coma-Cros, Alexandre Lancelot, María San Anselmo et al. · 2019 · Biomaterials Science

Biomaterials for antimalarial drug transport still need to be investigated in order to attain nanocarriers that can tackle essential issues related to malaria treatment, e.g. complying with size requirements and targeting specificity for their entry into Plasmodium-infected red blood cells (pRBCs), and limiting premature drug elimination or drug resistance evolution. Two types of dendritic macromolecule that can form vehicles suitable for antimalarial drug transport are herein explored. A new hybrid dendritic-linear-dendritic block copolymer based on Pluronic® F127 and amino terminated 2,2'-bi

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Negative / Null Result ReportOpen accessMaterials Science

The significant effect of size and concentrations of iron oxide nanoparticles on magnetic resonance imaging contrast enhancement

Mohammad W. Marashdeh, Baker Ababneh, O. M. Lemine et al. · 2019 · Results in Physics

In this study, iron oxide (γ-Fe2O3) nanoparticles (IONs) were successfully synthesized using sol-gel method, and characterized by XRD and VSM. The potential application of the differently sized IONs (22 nm and 30 nm) as magnetic resonance…

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Negative / Null Result ReportMaterials Science

Nascent particle sizes and degrees of entanglement are responsible for the significant differences in impact strength of ultrahigh molecular weight polyethylene

Huan Zhang, Shicheng Zhao, Xin Yu et al. · 2019 · Journal of Polymer Science Part B Polymer Physics

ABSTRACT The physical properties of ultrahigh molecular weight polyethylene (UHMWPE) are generally highly dependent on its molecular weight. However, in our study, it was found that two UHMWPE samples of similar molecular weight, SLL‐5 and…

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Negative / Null Result ReportMaterials Science

Significant effect of spin flip on the oxygen atom transfer reaction from (oxo)manganese(v) corroles to thioanisole: insights from density functional calculations

Chun Zhu, Jinxia Liang, Binju Wang et al. · 2012 · Physical Chemistry Chemical Physics

The electronic and structural features of (oxo)manganese(V) corroles and their catalyzed oxygen atom transfers to thioanisole in different spin states have been investigated by the B3LYP functional calculations. Calculations show that…

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Negative / Null Result ReportOpen accessMaterials Science

Mycobacterium tuberculosis Rv3406 Is a Type II Alkyl Sulfatase Capable of Sulfate Scavenging

Kimberly M. Sogi, Zev J. Gartner, Mark A. Breidenbach et al. · 2013 · PLoS ONE

The genome of Mycobacterium tuberculosis (Mtb) encodes nine putative sulfatases, none of which have a known function or substrate. Here, we characterize Mtb's single putative type II sulfatase, Rv3406, as a non-heme iron (II) and α-ketoglutarate-dependent dioxygenase that catalyzes the oxidation and subsequent cleavage of alkyl sulfate esters. Rv3406 was identified based on its homology to the alkyl sulfatase AtsK from Pseudomonas putida. Using an in vitro biochemical assay, we confirmed that Rv3406 is a sulfatase with a preference for alkyl sulfate substrates similar to those processed by Ats

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Negative / Null Result ReportOpen accessMaterials Science

Innovative Strategies to Overcome Stability Challenges of Single-Atom Nanozymes

Rong Guo, Qiuzheng Du, Yaping He et al. · 2026 · Nano-Micro Letters

Single-atom nanozymes (SAzymes) exhibit exceptional catalytic efficiency due to their maximized atom utilization and precisely modulated metal-carrier interactions, which have attracted significant attention in the biomedical field. However, stability issues may impede the clinical translation of SAzymes. This review provides a comprehensive overview of the applications of SAzymes in various biomedical fields, including disease diagnosis (e.g., biosensors and diagnostic imaging), antitumor therapy (e.g., photothermal therapy, photodynamic therapy, sonodynamic therapy, and immunotherapy), antim

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Negative / Null Result ReportOpen accessMaterials Science

Solar methane pyrolysis in a liquid metal bubble column reactor: Effect of medium type and gas injection configuration

Malek Msheik, Sylvain Rodat, Stéphane Abanades · 2024 · Journal of Analytical and Applied Pyrolysis

Solar methane pyrolysis in different molten media and reactor configurations was experimented to improve hydrogen production . Pure Sn, Ni 0.18 Sn 0.82 , Cu 0.45 Bi 0.55 , and KCl melts were compared at three different temperatures…

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Negative / Null Result ReportOpen accessMaterials Science

Fast Dissolving Resveratrol–Polyvinylpyrrolidone Nanofibrous Films Fabricated in Bulk Using a Special Hole Electrospinning Technique

Qiuyun Guo, He Lv, Ran Dong et al. · 2026 · Polymers

Batch production of nanomaterials is highly desired for developing commercial nanoproducts. Here, a brand-new electrospinning method, termed hole electrospinning, was developed for batch production of drug-loaded polymeric nanofibers. Using resveratrol and polyvinylpyrrolidone as model drug and filament-forming matrix, respectively, both hole and single-needle electrospinning were conducted. The resultant nanofibrous films were compared in terms of morphology, physical and thermal properties, mechanical performance, fast-dissolution rate, and antioxidant activity. Analytical and characterizati

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Negative / Null Result ReportOpen accessMaterials Science

Electrospun PLA/PVP K90 Biphasic-Release Sublingual Film for Motion Sickness Treatment

Wenwen Zhang, Qilin Wang, Wei Yi et al. · 2026 · Biomolecules

To overcome the limitations of traditional motion sickness medications—slow onset of action, short duration of efficacy, and poor patient compliance—this study employed coaxial electrospinning technology. Poly(lactic acid) (PLA) and polyvinylpyrrolidone K90 (PVP K90) were used as composite carrier materials. The sheath layer is composed of highly hydrophilic PVP K90, loaded with the antihistamine diphenhydramine (DPH). The core layer, composed of biodegradable PLA with excellent sustained-release properties, carries the anticholinergic drug scopolamine hydrobromide (SH). This core–sheath nanos

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Negative / Null Result ReportOpen accessMaterials Science

Significant effect on annealing temperature and enhancement on structural, optical and electrical properties of zinc oxide nanowires

Suriati Paiman, T. Hui Ling, M. Husham et al. · 2020 · Results in Physics

This paper focused on the growth of zinc oxide nanowires on unannealed and annealed indium tin oxide-coated-coated glass substrates on the structural, optical, and electrical properties towards surface acoustic wave (SAW) piezoelectric…

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