Negative / Null Result ReportOpen accessAnesthesiology
Suborov Evgeny V, Smetkin Alexey A, Kondratiev Timofey V et al. · 2012 · BMC Anesthesiology
Abstract Background Mechanical ventilation with high tidal volumes may cause ventilator-induced lung injury (VILI) and enhanced generation of nitric oxide (NO). We demonstrated in sheep that pneumonectomy followed by injurious ventilation promotes pulmonary edema. We wished both to test the hypothesis that neuronal NOS (nNOS), which is distributed in airway epithelial and neuronal tissues, could be involved in the pathogenesis of VILI and we also aimed at investigating the influence of an inhibitor of nNOS on the course of VILI after pneumonectomy. Methods Anesthetized sheep underwent right pn
View details →Negative / Null Result ReportOpen accessAnesthesiology
Nitika Vyas, Dinesh K Sahu, Reena Parampill · 2010 · Journal of Anaesthesiology Clinical Pharmacology
Background: Sufentanil added to intrathecal bupivacaine for cesarean section has shown to improve intraoperative and postoperative analgesia with no adverse effects on the mother and neonate. We compared the effects of intrathecal sufentanil 5 mcg and placebo when administered with hyperbaric bupivacaine 0.5% 11 mg for cesarean section. Patients and Methods: Sixty parturients of ASA grading I and II of age between 18 to 45 years scheduled for elective cesarean section under subarachnoid block were randomly allocated into one of the two groups to receive 5μg sufentanil + 0.2ml sterile, preserva
View details →Negative / Null Result ReportOpen accessAnesthesiology
Volkan Hancı, Şule Özbilgin, Seda Özbal et al. · Revista Brasileira de Anestesiologia
Abstract Background: Intra-arterial injection of medications may cause acute and severe ischemia and result in morbidity and mortality. There is no information in the literature evaluating the arterial endothelial effects of sugammadex and dexmedetomidine. The hypothesis of our study is that sugammadex and dexmedetomidine will cause histological changes in arterial endothelial structure when administered intra-arterially. Methods: Rabbits were randomly divided into 4 groups. Group Control (n = 7); no intervention performed. Group Catheter (n = 7); a cannula inserted in the central artery of th
View details →Negative / Null Result ReportOpen accessAnesthesiology
Orhan Kılıç, Murat Yaşar Özkalkanlı, Fulya Yılmaz et al. · 2022 · Ain Shams Journal of Anesthesiology
Abstract Background Malnutrition is an important and widespread problem in hospitalised elderly orthopaedic patients. It is an important predictor of morbidity and mortality and has been associated with an increased risk of complications. Although it is a common problem in the elderly, there is neither a universally accepted criterion for the diagnosis of malnutrition nor a screening tool accepted as the gold standard to detect patients at risk of malnutrition. There is still no consensus on which is the most recommended for screening hospitalised patients for nutritional risk. The aim of this
View details →Negative / Null Result ReportOpen accessAnesthesiology
Marzieh khalaji, Mohadese Babaie, Fatemeh Bayat et al. · 2025 · BMC Anesthesiology
Abstract Aim This study aims at comparing the impact of Magnesium Sulfate and Lidocaine sprays on hemodynamic changes after laryngoscopy and tracheal intubation. Design This double-blind clinical trial (code IRCT20230719058846N1) was conducted on the patients undergoing elective surgery in the city of Karaj. Methods A total of 100 patients, aged 18 to 40 years and classified as ASA I or II, who were candidates for elective surgery, were randomly assigned to two equal groups. Prior to intubation, patients received lidocaine spray (5 puffs of Lidocaine 10%) in one group, and magnesium sulfate sp
View details →Negative / Null Result ReportOpen accessAnesthesiology
Mayureshkumar Pareek, Vandana Parmar, Jigisha Badheka et al. · 2018 · Indian Journal of Anaesthesia
Background and Aims: Nurses should have cardiopulmonary resuscitation (CPR) knowledge and skills to be able to implement effective interventions during in-hospital cardiac arrest. The aim of this descriptive study was to assess mortality impact after nurses' CPR training with pre-CPR training data at our institute. Methods: Training regarding CPR was given to nurses, and CPR mortality 1-year before basic life support (BLS) and advanced cardiac life support (ACLS) training were collected and compared with post-training 1-year CPR mortality. Results: A total of 632 adult patients suffering in-ho
View details →Negative / Null Result ReportOpen accessAnesthesiology
Hasanul Arifin, Heru Kurniawan · 2016 · Jurnal Anestesi Perioperatif
Serum creatinine has many limitations when being used to diagnose acute kidney injury (AKI), especially in the scope of intensive care unit due to its low sensitivity to depict the kidney dysfunctional level of critically-ill patients. Out of numerous new available biological markers, four biological markers are widely used all over the world to detect AKI, e.g. neutrophil gelatinase-associated lipocalin (NGAL), cystatin C, KIM-1, and interleukin-18. The purpose of this study was to determine the sensitivity and specificity of serum cystatin C and creatinine in establishing the diagnosis of ac
View details →Negative / Null Result ReportOpen accessAnesthesiology
Mahmoodzadeh Hossein, Movafegh Ali, Beigi Noshin · 2009 · Saudi Journal of Anaesthesia
Background: Dextromethorphan, the D-isomer of the codeine analog levorphanol, is a weak, noncompetitive N-Methyl-D-Aspartate (NMDA) receptor antagonist. It has been suggested that NMDA receptor antagonists induce preemptive analgesia when administered before tissue injury occurs, thus decreasing the subsequent sensation of pain. Materials and Methods: The study was conducted in the Dr. Ali Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran, between February 2005 and December 2006. In this study, 72 patients scheduled for elective cholesyctectomy were randomized into three g
View details →Negative / Null Result ReportOpen accessAnesthesiology
Christian Rothe, Jørgen Lund, Morten Troels Jenstrup et al. · 2020 · BMC Anesthesiology
Abstract Background The sensory innervation of the shoulder is complex and there are variations in the branching patterns of the sensory fibres. Articular branches from the axillary nerve to the subacromial bursa are described in more than 50% of investigated shoulders but the isolated contribution of sensory input from the axillary nerve has never been investigated clinically. We hypothesized that a selective block of the axillary nerve would reduce morphine consumption and pain after arthroscopic subacromial decompression. Methods We included 60 patients in a randomized, blinded, placebo-con
View details →