Prognostic significance of CD44s expression in resected non-small cell lung cancer
Ko Yoon; Won Hye; Jeon Eun; Hong Sook; Roh Sang; Hong Young; Byun Jae; Jung Chan-Kwon · 2011 · BMC Cancer
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Abstract
Abstract Background CD44s is a cell adhesion molecule known to mediate cellular adhesion to the extracellular matrix, a prerequisite for tumor cell migration. CD44s plays an important role in invasion and metastasis of various cancers. In the present study, we sought to determine whether CD44s is involved in clinical outcomes of patients with resected non-small cell lung cancer (NSCLC). Methods Using immunohistochemical staining, we investigated CD44s protein expression using tissue array specimens from 159 patients with resected NSCLC (adenocarcinoma (AC; n = 82) and squamous cell carcinoma (
Abstract by Ko Yoon; Won Hye; Jeon Eun; Hong Sook; Roh Sang; Hong Young; Byun Jae; Jung Chan-Kwon, BMC Cancer (2011) — licensed CC BY 4.0.
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Metadata source: DOAJ · DOI 10.1186/1471-2407-11-340