e-ISSN: Pending
Negative / Null Result ReportOpen accessNeoplasms. Tumors. Oncology. Including cancer and carcinogens

Secretory Function of Kupffer Cells in Liver Cancer After Cryoablation

ZHU Yaling; YI Fengtao; DING Mengnan; ZENG Cheng; XU Zhenhua; SHAO Zhixiong; XIE Junjie · 2020 · Zhongliu Fangzhi Yanjiu

WASTE classifies this as Negative / Null Result Report · AI classification, approximate

The study found no significant effect — useful as a negative control or null benchmark for your own design.

Abstract

Objective To explore the effect of Kupffer cells (KCs) secretion on HCC cells after cryoablation and its mechanism. Methods Sixteen groups were divided:37℃ control group, three hypothermia groups(0℃, 5℃, 10℃), freeze-thaw necrotic substances group, three combined stimulation group and 8 parallel groups for each group. In the 8 parallel groups, pyrrolidine dithiocarbamate(PDTC) was added, and the final concentration was 100 μmol/ml. The concentration of TNF-α, IL-1β and INF-γ in 16 groups of KCs supernatant were determined by Elisa method. The expression of NF-κB protein in each group was detec

Abstract by ZHU Yaling; YI Fengtao; DING Mengnan; ZENG Cheng; XU Zhenhua; SHAO Zhixiong; XIE Junjie, Zhongliu Fangzhi Yanjiu (2020) — licensed CC BY 4.0.

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Metadata source: DOAJ · DOI 10.3971/j.issn.1000-8578.2020.19.0801