Effect of antiangiogenic-based treatment and systemic inflammatory factors on outcomes in patients with BRAF v600-mutated metastatic colorectal cancer: a real-world study in Spain
Nieves Martínez-Lago; Ana Fernández-Montes; Marta Covela; Elena M. Brozos; Juan De la Cámara; José C. Méndez Méndez; Mónica Jorge-Fernández; Antía Cousillas Castiñeiras · 2021 · BMC Cancer
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract
Abstract Background Outcomes are poorer in metastatic colorectal cancer (mCRC) patients with BRAF V600E mutations than those without it, but the effect of these mutations on treatment response is unclear. This real-world study assessed the effects of antiangiogenic-based treatment and systemic inflammatory factors on outcomes in patients with BRAF V600-mutated mCRC. Methods This real-world, multicenter, retrospective, observational study included patients with BRAF V600-mutated mCRC treated in eight hospitals in Spain. The primary endpoints were overall survival (OS) and progression-free survi
Abstract by Nieves Martínez-Lago; Ana Fernández-Montes; Marta Covela; Elena M. Brozos; Juan De la Cámara; José C. Méndez Méndez; Mónica Jorge-Fernández; Antía Cousillas Castiñeiras, BMC Cancer (2021) — licensed CC BY 4.0.
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Metadata source: DOAJ · DOI 10.1186/s12885-020-07758-5