Exercise training does not improve myocardial diastolic tissue velocities in Type 2 diabetes
Nenonen Arja; Rinne Marjo; Groundstroem Kaj; Loimaala Antti; Huhtala Heini; Vuori Ilkka · 2007 · Cardiovascular Ultrasound
WASTE classifies this as Failed Experiment Report · AI classification, approximate
An experimental approach did not work as intended — learn what to avoid before investing the same effort.
Abstract
Abstract Background Myocardial diastolic tissue velocities are reduced already in newly onset Type 2 diabetes mellitus (T2D). Poor disease control may lead to left ventricular (LV) systolic dysfunction and heart failure. The aim of this study was to assess the effects of exercise training on myocardial diastolic function in T2D patients without ischemic heart disease. Methods 48 men (52.3 ± 5.6 yrs) with T2D were randomized to supervised training four times a week and standard therapy (E), or standard treatment alone (C) for 12 months. Glycated hemoglobin (HbA 1c ), oxygen consumption (VO 2max
Abstract by Nenonen Arja; Rinne Marjo; Groundstroem Kaj; Loimaala Antti; Huhtala Heini; Vuori Ilkka, Cardiovascular Ultrasound (2007) — licensed CC BY 4.0.
About to run something similar?
Run an AI Precheck on your own design to catch failure modes like this one before you spend the time. Your first desk check is free.
Related failures
Rejuvenated Circulating Endothelial Progenitor Cells and Nitric Oxide in Premenopausal Women with Hyperhomocysteinemia
Negative / Null Result ReportMonocyte matrix metalloproteinase production in Type 2 diabetes and controls – a cross sectional study
Negative / Null Result ReportComparison short time discharge with long time discharge following uncomplicated percutaneous coronary intervention for Non-ST elevation myocardial infarction patients
Negative / Null Result ReportOral milrinone for management of refractory right ventricular failure in patients with left ventricular assist devices
Negative / Null Result ReportReciprocal ST segment changes in acute inferior myocardial infarction: Clinical, hemodynamic and angiographic implications
Negative / Null Result ReportThe effect of subchronic cigarette smoke exposure on oxidative stress parameters and endothelial nitric oxide synthase in a rat aorta
WASTE indexes this work — it does not host or republish it. Failure-type classification is automated and approximate.
Metadata source: DOAJ · DOI 10.1186/1476-7120-5-32