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Failure-mode index

Search what already failed

A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.

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WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.

By fieldMedicine 12,214Computer Science 743Biochemistry, Genetics and Molecular Biology 414Social Sciences 302Psychology 299Physics 280Neuroscience 243Economics, Econometrics and Finance 196Environmental Science 171Mathematics 155Agricultural and Biological Sciences 137Engineering 135

24 results in Failed Experiment Report for "aging"

Failed Experiment ReportOpen accessEnvironmental Science

Foraging ecology and coexistence of Asiatic black bears and sun bears in a seasonal tropical forest in Southeast Asia

Robert Steinmetz, David L. Garshelis, Wanlop Chutipong et al. · 2013 · Journal of Mammalogy

Asiatic black bears (Ursus thibetanus) and sun bears (Helarctos malayanus) are ecologically similar and coexist extensively across Southeast Asia. We used foraging signs identified to bear species to examine their food selection and…

View details →DOI: 10.1644/11-mamm-a-351.1Cited by 92
Failed Experiment ReportMedicine

Managing post-laminoplasty deformity after resection in of a cervical intramedullary hemangioblastoma in a 36-year-old male: a case report.

Versyck, Tollenaere, Schelfaut et al. · 2026 · Journal of spine surgery (Hong Kong)

Cervical kyphotic deformity is a recognized complication following posterior cervical spine surgery, particularly after laminectomy. However, post-laminoplasty kyphosis remains an underreported entity. We present a case of progressive…

View details →DOI: 10.21037/jss-2025-1-227
Failed Experiment ReportOpen accessPsychology

Resource scarcity priming and face perception: A preregistered conceptual replication of Study 1 of Rodeheffer et al. (2012) in Japan

Masataka Takebe, Kenta Tsumura, Ken'ichiro Nakashima · 2023 · Current Research in Ecological and Social Psychology

Rodeheffer et al. (2012) showed that when people perceive resource scarcity, they are more likely to judge racially ambiguous people as out-group members. In their first experiment, 71 White participants viewed a slideshow depicting either resource scarcity or abundance; subsequently, they judged 20 biracial faces created by averaging a White and a Black face. We conducted this experiment's preregistered conceptual replication study in Japan. Specifically, after observing a slideshow depicting either resource scarcity or abundance, East Asian participants judged 20 biracial faces produced by a

View details →DOI: 10.1016/j.cresp.2023.100169
Failed Experiment ReportMedicine

Investigation of the relationship between background parenchymal enhancement and breast cancer using 3.0 Tesla magnetic resonance imaging.

Sekmen S, Hursoy N, Panc K et al. · 2026 · Clinical imaging

Aim This study aims to explore the correlation between background parenchymal enhancement (BPE) observed in breast magnetic resonance imaging (MRI) and the presence of breast cancer. Materials and methods A total of 761 patients (326…

View details →DOI: 10.1016/j.clinimag.2025.110680
Failed Experiment ReportMedicine

Testing the effects of pathogen threat and sexual strategies on political ideology.

Shook NJ, Oosterhoff B · 2020 · Politics and the life sciences : the journal of the Association for Politics and the Life Sciences

Disgust has been consistently associated with greater political conservatism. Two explanations have been proposed for this link. According to a pathogen threat model, disgust serves a pathogen-avoidance function, encouraging more…

View details →DOI: 10.1017/pls.2020.19
Failed Experiment ReportMedicine

Solitary Humeral Metastasis in the Absence of Detectable Primary Neuroblastoma on Triple-tracer Imaging With 18F-FDG, 123I-MIBG, and 68Ga-DOTATATE.

Li S, Lv C, Xie P et al. · 2026 · Clinical nuclear medicine

A 6-year-old boy presented with a 2-month history of fever of unknown origin. 18F-FDG PET/CT was performed to identify the potential source, revealing a solitary focus of abnormal radiotracer uptake in the left humerus. Bone marrow biopsy…

View details →DOI: 10.1097/rlu.0000000000006250
Failed Experiment ReportOpen accessMedicine

Loss of the distal-proximal GLP-1/Notch activation gradient in the aging <i>C. elegans</i> germline.

Janse van Vuuren R, Martel PO, Narbonne P · 2025 · microPublication biology

In C. elegans hermaphrodites, the distal tip cells (DTCs) capping the gonad arms provide a Notch ligand, the niche signal that maintains germline stem cell pools. Using fixed germlines, it was recently shown that the transcription of a…

View details →DOI: 10.17912/micropub.biology.001908
Failed Experiment ReportOpen accessMedicine

Effects of Clobetasol in an Aging Mouse Model of Spinal Cord Hemisection.

Ciuro M, Sangiorgio M, Cantone G et al. · 2025 · Biology

Spinal cord injury leads to permanent neurological deficits, and aging further diminishes the plasticity and regenerative responses required for recovery. Activation of the Sonic hedgehog (Shh) pathway through the receptor Smoothened (Smo)…

View details →DOI: 10.3390/biology14111595
Failed Experiment ReportMedicine

Embryo developmental and morphokinetic patterns in the domestic cat (Felis catus): associations with maternal age and SRT1720 supplementation during oocyte in vitro maturation.

Meco M, Carreira RP, Ochota M et al. · 2026 · Theriogenology

This study describes embryo developmental progression and morphokinetic patterns in embryos derived from oocytes of young and aged domestic cats, a model for endangered felids, using a time-lapse monitoring system. Because maternal aging…

View details →DOI: 10.1016/j.theriogenology.2026.118026
Failed Experiment ReportMedicine

Foraging crumbles reduce severe aggression in laboratory mice.

Bennett MB, Booth AB, Murdoch EQ et al. · 2026 · Physiology & behavior

Providing foraging crumbles in mouse cages is one method used in efforts to reduce aggression in laboratory mice. However, no studies have yet examined the effects of this procedure. Therefore, we investigated whether foraging crumbles…

View details →DOI: 10.1016/j.physbeh.2026.115401
Failed Experiment ReportMedicine

Can machine learning predict vessels that encapsulates tumor cluster ptterns and histological differentiation in solitary small (< 5 cm) hepatocellular carcinoma?

Toshida K, Sugitani Y, Itoh S et al. · 2026 · Surgery today

Hepatocellular carcinoma (HCC) is a leading cause of cancer-related mortality. Machine learning (ML) may enable the noninvasive prediction of histopathological features using clinical and imaging data. This study evaluated the utility of…

View details →DOI: 10.1007/s00595-026-03317-w
Failed Experiment ReportMedicine

Is exergaming a viable exercise option for obese black women?

Hicks J, Dash C, Smith D et al. · 2025 · Contemporary clinical trials

Background Physical inactivity and obesity, which are disproportionately higher in Black women, are known risk factors of breast cancer. Novel methods to address this public health concern involve leveraging screen-viewing activities to…

View details →DOI: 10.1016/j.cct.2025.107846
Failed Experiment ReportOpen accessMedicine

Conventional versus advanced imaging selection for endovascular treatment of basilar artery occlusion strokes.

Chen H, Colasurdo M, Matsukawa H et al. · 2025 · European stroke journal

Introduction Endovascular thrombectomy (EVT) is an effective treatment for basilar artery occlusion (BAO) stroke in select patients. While there is a growing body of literature suggesting that advanced imaging modalities such as computed…

View details →DOI: 10.1177/23969873251364973
Failed Experiment ReportMedicine

Diagnostic utility and limitations of CT-guided transthoracic fine-needle aspiration biopsy in Lung-RADS 4 pulmonary nodules ≤2 cm.

Cengiz SK, Demirer E, Baysal T et al. · 2026 · Annals of Saudi medicine

Background Managing small Lung-RADS 4 pulmonary nodules is clinically challenging. While CT-guided TTFNAB is standard, its efficacy and safety for lesions ≤2 cm require further evaluation to optimize outcomes and reduce unnecessary…

View details →DOI: 10.5144/0256-4947.2026.225
Failed Experiment Report

State-of-the-Art Mediastinal Staging in Non-Small-Cell Lung Cancer: Integration of Combined Endosonographic Techniques with Updated IASLC TNM 9th Classification

Alkathiri O, Liberman M · 2026 · Preprint

Mediastinal staging remains a critical step in the management of non-small-cell lung cancer (NSCLC), as it directly impacts treatment planning, surgical decision-making, and overall prognosis. For many years, mediastinoscopy was considered…

View details →DOI: 10.20944/preprints202604.0470.v1
Failed Experiment ReportOpen accessMedicine

Photoperiod, but not testosterone, increases basal metabolic rate in house sparrows.

Galante H, Lane SJ, Elderbrock EK et al. · 2026 · Integrative organismal biology (Oxford, England)

Organisms in natural environments often undergo life history stage transitions that optimize behaviors (i.e., migration, reproduction, and foraging) with environmental conditions. These changes in behavior are facilitated by changes in…

View details →DOI: 10.1093/iob/obag013
Failed Experiment ReportOpen accessMedicine

EVALUATION OF FLEXURAL STRENGTH OF DIFFERENT RESTORATIVE MATERIALS

Almira Ada Diken Türksayar, Simge Baytur · 2023 · Sabiad

Objective: The aim of this in vitro study was to compare the biaxial flexural strengths of permanent restorative materials produced by additive manufacturing and milling after thermal aging. Material and methods: For this study, three study groups were formed by producing disc-shaped specimens with a 3D printer (Form3, Formlabs) using permanent crown material (Permanent Crown, Somerville, MA) and two different resin-containing materials (Brilliant Crios,Coltene/ Whaledent; Cerasmart, GC Europe) by the milling method (n=10). The entire production process was carried out in accordance with the m

View details →DOI: 10.26650/jarhs2023-1200694
Failed Experiment ReportMedicine

Learning from late-stage trial failures in higher-risk myelodysplastic syndromes: towards adaptive and biomarker-enriched designs.

Zeidan AM, Aakko S, Stahl M et al. · 2026 · Expert review of anticancer therapy

Introduction Higher-risk myelodysplastic syndromes (HR-MDS) remain an area of high unmet need in which multiple randomized late-stage trials have failed to improve outcomes beyond hypomethylating agent monotherapy, despite encouraging…

View details →DOI: 10.1080/14737140.2026.2640238