A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.
730 results in Negative / Null Result Report for "aging" · page 9 of 25
Salman A · 2026 · Journal of ophthalmology
Purpose To evaluate and compare the topographic and tomographic characteristics of post-laser in situ keratomileusis (LASIK) ectasia (PLE) with keratoconus (KC) and normal control eyes using the Sirius imaging system. Methods This…
Yamazaki M, Ninomiya S, Hashizume A et al. · 2026 · Preprint
Abstract Background About half of both men and women have lower urinary tract symptoms, and aging is reported to have a significant impact on these symptoms. Lifestyle-related diseases such as diabetes, hypertension, and metabolic syndrome…
Trevethan, Doig, Patterson et al. · 2026 · Lymphology
ICG lymphography is a lymphatic imaging tool that can inform lymphedema treatment, including self-management. Self-management requires patient engagement in a multimodal treatment program. However, lack of knowledge about lymphedema,…
Huang, Tsai, Lin et al. · 2026 · Taiwanese journal of obstetrics & gynecology
A higher oocyte yield is generally associated with improved outcomes in assisted reproductive technology (ART). Vitrification enables the accumulation of oocytes, zygotes, or embryos across multiple cycles, offering a potential strategy to…
Mahdavi Sabet, Zeinalkhani, Forghani et al. · 2026 · International journal of breast cancer
This study is aimed at investigating the correlation between apparent diffusion coefficient (ADC) values obtained from diffusion-weighted imaging (DWI) and prognostic factors in breast cancer. We hypothesized that lower ADC values would be…
Zhaoying Li, Shanyu Liu, Yuling Shen et al. · 2025 · Frontiers in Neuroscience
BackgroundAbnormalities in brain activity patterns during episodic memory tasks have been inconsistently reported in amnestic mild cognitive impairment (aMCI) patients using functional magnetic resonance imaging (fMRI). This study applied traditional Chinese medicine (TCM) syndrome differentiation to categorize aMCI patients into distinct subgroups, aiming to clarify the neural mechanisms underlying their cognitive profiles.MethodsParticipants included aMCI patients categorized into the turbid phlegm clouding the orifices (PCO) or spleen-kidney deficiency (SKD) syndrome subgroups, alongside co
Darrah, Spence · 2026 · American journal of veterinary research
To compare the proportion of lesions identified on cervical MRI in dogs based on weight. Medical records from a tertiary referral hospital were reviewed for dogs that underwent cervical MRI to investigate clinical signs consistent with…
Chittamuru, Vengamma, Priya et al. · 2026 · Journal of maxillofacial and oral surgery
During the second wave of COVID-19 pandemic, there was surge in reporting of COVID-19-associated mucormycosis cases. Government of India declared rhino-orbito-cerebral mucormycosis as a notifiable disease. Managing this condition posed a…
Kannikeswaran, Sivaswamy, Przyklenk et al. · 2026 · Pediatric neurology
Although not routinely recommended, computed tomography (CT) head are frequently performed in children presenting to emergency department (ED) with seizures. Racial and ethnic disparities have been reported in pediatric ED imaging. Our…
Y. S. Kudryavtsev, M. M. Beregov, A. B. Berdalin et al. · 2021 · Вестник рентгенологии и радиологии
Objective: to compare the results of staging the severity of viral pneumonia in patients with COVID-19 based on the results of chest computed tomography (CT) using the empirical visual scale CT 0–4 and chest CT severity score (CT-SS) point scale, as well as to assess their prognostic value.Material and methods. Chest CT scans and anamnestic data in patients hospitalized to a non-specialized center repurposed for the treatment of new coronavirus infection, were analyzed. Chest CT analysis was performed by two radiologists using CT 0–4 and CT-SS scales.Results. The time course of changes in the
Liu, Xu, Zhong et al. · 2026 · Quantitative imaging in medicine and surgery
Intracranial atherosclerosis is the predominant etiology of ischemic stroke in East Asian populations. Atherosclerotic progression frequently involves concomitant vascular remodeling, and stroke risk profiles may vary across distinct…
Ciacciarelli, Nicolini, Saia et al. · 2026 · Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology
Infarct growth rate (IGR) is highly heterogeneous among ischemic stroke patients, reflecting a spectrum of progressor phenotypes with clinical implications. We aim to compare different imaging approaches to investigate stroke progressors…
Panwar, Amiri-Kazaz, Szczepaniec · 2026 · Environmental entomology
Amauromyza karli Hendel (Diptera: Agromyzidae) has recently emerged as a damaging stem-boring pest of quinoa in Colorado and other quinoa-producing regions of the United States. Severe infestations have been associated with substantial…
Zeren G, Bakır EO, Tufaro V et al. · 2026 · Journal of cardiovascular development and disease
Intravascular imaging (IVI) was introduced 35 years ago to assess coronary artery pathology and plaque vulnerability. However, from its first applications it became apparent that it can also be useful in percutaneous coronary intervention…
Lin, Li, Cheng et al. · 2026 · Briefings in bioinformatics
Current metabolomics approaches predominantly rely on group-level differential abundance screening. While effective for identifying biomarkers, this paradigm often overlooks upstream regulatory hubs and fails to resolve the…
Malzahn, Höft Budde, Kneißl et al. · 2026 · Innere Medizin (Heidelberg, Germany)
The German healthcare system, despite its high performance, fails to achieve the goal of needs-based service provision. Supply-induced demand, regional disparities and misaligned financial incentives lead to overuse, underuse and misuse of…
Bedia Cadelo, García Feijoo, Zamorano-Fernandez et al. · 2026 · BMJ case reports
A boy in his early teens presented with transient visual disturbances and headache. Brain imaging revealed bilateral occipital infarctions, while vascular studies demonstrated bilateral V3 vertebral artery wall abnormalities with…
Prandani, Fuadi, Halimi et al. · 2026 · Surgical neurology international
Early recognition of postoperative neurologic deterioration in patients with traumatic brain injury (TBI) is essential but remains challenging, as clinical assessment may lack sensitivity and computed tomography (CT) imaging is not always…
Li, Zhang, Leng et al. · 2026 · IEEE journal of biomedical and health informatics
Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder that requires early and efficient diagnosis. Functional magnetic resonance imaging (fMRI), with high temporal and spatial resolution, is a powerful tool for…
Jumah, Brooks, Siddiq et al. · 2026 · Missouri medicine
Chronic carotid occlusion (CCO) carries a significant risk of ischemic stroke, particularly in patients with impaired cerebrovascular reserve. Extracranial-intracranial (EC-IC) bypass emerged as a popular treatment strategy with high…
Zhao, Fu, Li et al. · 2026 · Frontiers in neuroscience
Sleep apnea and hypopnea syndrome (SAHS) is a prevalent disorder with profound adverse effects on health and overall quality of life, thereby necessitating the development of accurate and accessible screening tools. Electrocardiogram…
Zhao, Xie, Yu et al. · 2026 · BMC cancer
BACKGROUND: Vessels that encapsulate tumor clusters (VETC) is a powerful predictor of aggressive hepatocellular carcinoma (HCC) and associated with poor outcomes of HCC. Imaging surrogates of VETC potentially help predict postsurgical…
Yang, Liu, Yu et al. · 2026 · Frontiers in nutrition
This study aimed to examine the individual and combined associations of tea consumption and cigarette smoking with accelerated biological aging among oilfield workers. Logistic regression was used to assess the associations of tea…
Tsai, Huang, Wang et al. · 2026 · Integrative cancer therapies
BackgroundTraditional, complementary, and integrative medicine (TCIM) is an evolving field in oncology focused on managing cancer symptoms. Hydrogen water (HW) has gained attention for its antioxidant and anti-inflammatory properties, yet…
Gâta, Ilieș, Mureșan-Bădescu et al. · 2026 · Diagnostics (Basel, Switzerland)
Background/Objectives : Nowadays, lymph node assessment represents a key component in the surgical staging of endometrial cancer, as sentinel lymph node (SLN) mapping increased in adoption as an alternative to lymphadenectomy. This study…
Vageesh Saxena, Sharid Loáiciga, Nils Rethmeier · 2024 · arXiv
Neural networks have demonstrated significant advancements in Neural Machine Translation (NMT) compared to conventional phrase-based approaches. However, Multilingual Neural Machine Translation (MNMT) in extremely low-resource settings remains underexplored. This research investigates how knowledge transfer across languages can enhance MNMT in such scenarios. Using the Tatoeba translation challenge dataset from Helsinki NLP, we perform English-German, English-French, and English-Spanish translations, leveraging minimal parallel data to establish cross-lingual mappings. Unlike conventional meth
Bill Cheuk Long Chan, Billy Lee · 2024 · Studia sportiva
Managing the balance of academic and athletic responsibilities at university is a serious challenge for student athletes. This phenomenological case study illuminates how one individual successfully managed his study-sport balance at…
Daniel I. Rhon, Tina A. Greenlee, Rachel Mayhew et al. · 2022 · Journal of the American Academy of Orthopaedic Surgeons
Introduction: After elective orthopaedic surgery, many individuals go on to become long-term opioid users. Mitigating this risk has become a priority for surgeons, other members of the medical care team, and healthcare systems. The purpose…
William Zhang, Wan Shen Lim, Andrew Pavlo · 2026 · Proceedings of the ACM on Management of Data
Tuning database management systems (DBMSs) is challenging due to trillions of possible configurations and evolving workloads. Recent advances in tuning have led to breakthroughs in optimizing over the possible configurations. However, due…
Anirudh Vemula, J. Andrew Bagnell, Maxim Likhachev · 2020 · arXiv
Given access to accurate dynamical models, modern planning approaches are effective in computing feasible and optimal plans for repetitive robotic tasks. However, it is difficult to model the true dynamics of the real world before execution, especially for tasks requiring interactions with objects whose parameters are unknown. A recent planning approach, CMAX, tackles this problem by adapting the planner online during execution to bias the resulting plans away from inaccurately modeled regions. CMAX, while being provably guaranteed to reach the goal, requires strong assumptions on the accuracy