Distinct brain activity patterns associated with traditional Chinese medicine syndromes: a task-fMRI study of mild cognitive impairment
Zhaoying Li; Shanyu Liu; Yuling Shen; Huan Zhao; Zhenwei Chen; Rui Tan; Zhuoling Li; Ling Quan · 2025 · Frontiers in Neuroscience
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Abstract
BackgroundAbnormalities in brain activity patterns during episodic memory tasks have been inconsistently reported in amnestic mild cognitive impairment (aMCI) patients using functional magnetic resonance imaging (fMRI). This study applied traditional Chinese medicine (TCM) syndrome differentiation to categorize aMCI patients into distinct subgroups, aiming to clarify the neural mechanisms underlying their cognitive profiles.MethodsParticipants included aMCI patients categorized into the turbid phlegm clouding the orifices (PCO) or spleen-kidney deficiency (SKD) syndrome subgroups, alongside co
Abstract by Zhaoying Li; Shanyu Liu; Yuling Shen; Huan Zhao; Zhenwei Chen; Rui Tan; Zhuoling Li; Ling Quan, Frontiers in Neuroscience (2025) — licensed CC BY 4.0.
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Metadata source: DOAJ · DOI 10.3389/fnins.2025.1555365