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Failure-mode index

Search what already failed

A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.

697 results in Negative / Null Result Report for "aging" · page 8 of 24

Negative / Null Result ReportMedicine

Sentinel Lymph Node Mapping Compared with Selective Lymph Node Sampling in the Surgical Staging of Endometrial Cancer: A Prospective Observational Study.

Gâta, Ilieș, Mureșan-Bădescu et al. · 2026 · Diagnostics (Basel, Switzerland)

Background/Objectives : Nowadays, lymph node assessment represents a key component in the surgical staging of endometrial cancer, as sentinel lymph node (SLN) mapping increased in adoption as an alternative to lymphadenectomy. This study…

View details →DOI: 10.3390/diagnostics16121904
Negative / Null Result ReportOpen accessComputer Science

Understanding and Analyzing Model Robustness and Knowledge-Transfer in Multilingual Neural Machine Translation using TX-Ray

Vageesh Saxena, Sharid Loáiciga, Nils Rethmeier · 2024 · arXiv

Neural networks have demonstrated significant advancements in Neural Machine Translation (NMT) compared to conventional phrase-based approaches. However, Multilingual Neural Machine Translation (MNMT) in extremely low-resource settings remains underexplored. This research investigates how knowledge transfer across languages can enhance MNMT in such scenarios. Using the Tatoeba translation challenge dataset from Helsinki NLP, we perform English-German, English-French, and English-Spanish translations, leveraging minimal parallel data to establish cross-lingual mappings. Unlike conventional meth

Negative / Null Result Report

“Football Did Not Make Me a World Champion, but It Did Help My Wellbeing”: A Qualitative Study of Study-sport Balance Based on Fung Ka Ki

Bill Cheuk Long Chan, Billy Lee · 2024 · Studia sportiva

Managing the balance of academic and athletic responsibilities at university is a serious challenge for student athletes. This phenomenological case study illuminates how one individual successfully managed his study-sport balance at…

View details →DOI: 10.5817/sts2023-2-6
Negative / Null Result ReportOpen accessMedicine

Age-Dependent Alterations of Chromosomal Passenger Complex Members During Implantation and Decidualization in the Mouse Uterus.

Golal E, Balci CN, Acar N · 2026 · Aging cell

Successful embryo development, acquisition of uterine receptivity, implantation, and decidualization during the peri-implantation window are essential events that ensure a healthy pregnancy. While ovarian aging has long been considered the…

View details →DOI: 10.1111/acel.70506
Negative / Null Result Report

Engaging Education About Risks of Opioid Use With Patients Before Elective Surgery of the Lower Extremity Did Not Reduce Postoperative Opioid Utilization: A Randomized Controlled Trial

Daniel I. Rhon, Tina A. Greenlee, Rachel Mayhew et al. · 2022 · Journal of the American Academy of Orthopaedic Surgeons

Introduction: After elective orthopaedic surgery, many individuals go on to become long-term opioid users. Mitigating this risk has become a priority for surgeons, other members of the medical care team, and healthcare systems. The purpose…

View details →DOI: 10.5435/jaaos-d-21-00603
Negative / Null Result Report

This is Going to Sound Crazy, But What If We Used Large Language Models to Boost Automatic Database Tuning Algorithms By Leveraging Prior History? We Will Find Better Configurations More Quickly Than Retraining From Scratch!

William Zhang, Wan Shen Lim, Andrew Pavlo · 2026 · Proceedings of the ACM on Management of Data

Tuning database management systems (DBMSs) is challenging due to trillions of possible configurations and evolving workloads. Recent advances in tuning have led to breakthroughs in optimizing over the possible configurations. However, due…

View details →DOI: 10.1145/3786704
Negative / Null Result ReportOpen accessComputer Science

CMAX++ : Leveraging Experience in Planning and Execution using Inaccurate Models

Anirudh Vemula, J. Andrew Bagnell, Maxim Likhachev · 2020 · arXiv

Given access to accurate dynamical models, modern planning approaches are effective in computing feasible and optimal plans for repetitive robotic tasks. However, it is difficult to model the true dynamics of the real world before execution, especially for tasks requiring interactions with objects whose parameters are unknown. A recent planning approach, CMAX, tackles this problem by adapting the planner online during execution to bias the resulting plans away from inaccurately modeled regions. CMAX, while being provably guaranteed to reach the goal, requires strong assumptions on the accuracy

Negative / Null Result ReportOpen accessMedicine

Efficacy of insecticide-infused hydrogel baits in managing European earwig (Dermaptera: Forficulidae) in citrus.

Dhungana SK, Gautam SG · 2026 · Journal of economic entomology

European earwig (Forficula auricularia L.) is an omnivorous insect commonly found in California citrus orchards. Often considered a beneficial predator, earwigs can damage young fruit, causing rind scarring and reducing the market value.…

View details →DOI: 10.1093/jee/toag108
Negative / Null Result ReportOpen accessEngineering

Audio-Conditioned Diffusion LLMs for ASR and Deliberation Processing

Mengqi Wang, Zhan Liu, Zengrui Jin et al. · 2025 · arXiv

Diffusion-based large language models (DLLMs) have recently attracted growing interest as an alternative to autoregressive decoders. In this work, we present an empirical study on using the diffusion-based large language model LLaDA for automatic speech recognition (ASR). We first investigate its use as an external deliberation-based processing module for Whisper-LLaMA transcripts. By leveraging the bidirectional attention and denoising capabilities of LLaDA, we explore random masking, low-confidence masking, and semi-autoregressive strategies, showing that Whisper-LLaDA substantially reduces

Negative / Null Result ReportOpen accessComputer Science

Towards the Design of Effective Freehand Gestural Interaction for Interactive TV

Gang Ren, Wenbin Li, Eamonn O'Neill · 2016 · arXiv

As interactive devices become pervasive, people are beginning to looking for more advanced interaction with televisions in the living room. Interactive television has the potential to offer a very engaging experience. But most common user tasks are still challenging with such systems, such as menu selection or text input. And little work has been done on understanding and sup-porting the effective design of freehand interaction with an TV in the living room. In this paper, we perform two studies investi-gating freehand gestural interaction with a consumer level sensor, which is suitable for TV

Negative / Null Result ReportOpen accessPhysics

Ground test results of the electromagnetic interference for the x-ray microcalorimeter onboard XRISM

Miki Kurihara, Masahiro Tsujimoto, Megan E. Eckart et al. · 2023 · arXiv

Electromagnetic interference (EMI) for low-temperature detectors is a serious concern in many missions. We investigate the EMI caused by the spacecraft components to the x-ray microcalorimeter of the Resolve instrument onboard the X-Ray Imaging and Spectroscopy Mission (XRISM), which is currently under development by an international collaboration and is planned to be launched in 2023. We focus on the EMI from (a) the low-frequency magnetic field generated by the magnetic torquers (MTQ) used for the spacecraft attitude control and (b) the radio-frequency (RF) electromagnetic field generated by

Negative / Null Result ReportOpen accessBusiness

Relationship of job level, burnout to job satisfaction and task performance in functional officers managing goods and services procurement in government institutions

Yuyun Sumirat, Rhian Indradewa · 2023 · Jurnal Ekonomi dan Bisnis

Emotional exhaustion, frustration or emotional or what is called burnout is the cause of bad work attitudes, unfocused concentration, and negative assessment of employees, in the world of work there are many things that affect a worker in achieving job satisfaction, factors that cause leaders and workers itself is not satisfied with the results of the work that has been completed due to fatigue, emotions, frustration. In this study, researchers used a sample of 166 employees of the Goods and Services Procurement Unit with a functional position as Goods/Services Procurement Manager for the Stat

View details →DOI: 10.24914/jeb.v26i1.4516
Negative / Null Result ReportOpen accessPhysics

Imaging method for interface rheological characterization

Nicolas Abi Chebel, Olivier Masbernat, Frédéric Risso et al. · 2008 · arXiv

The present work investigates free damped oscillations of an oil drop in water after its release from a capillary tube. Both pure heptane drops and diluted crude oil drops are considered (in the second case the interface is covered by amphiphilic species, natural components of crude oil). Shadowgraph images of the drops are taken by means of a high speed camera and the drop contour is detected by image processing. The axisymmetric drop shape is then decomposed into spherical harmonics, which constitute the eigenmodes of oscillations predicted by the Rayleigh-Lamb theory. Time evolution of each

Negative / Null Result ReportOpen accessPhysics

Photoelectron Polarization Vortexes in Strong-Field Ionization

Pei-Lun He, Zhao-Han Zhang, Karen Z. Hatsagortsyan et al. · 2024 · arXiv

The spin polarization of photoelectrons induced by an intense linearly polarized laser field is investigated using numerical solutions of the time-dependent Schrödinger equation in companion with our analytic treatment via the spin-resolved strong-field approximation and classical trajectory Monte Carlo simulations. We demonstrate that, even though the total polarization vanishes upon averaging over the photoelectron momentum, momentum-resolved spin polarization is significant, typically exhibiting a vortex structure relative to the laser polarization axis. The polarization arises from the tra

Negative / Null Result Report

Keep looking until you find

Nelli Tuomola · 2023 · JCEM Case Reports

Abstract The patient is 24-years old male with no previous medical history. He has worked for the last 3 years in the packaging line of Divigel, the estradiol gel of the pharmaceutical company Orion. He sought medical attention 11/2014 due…

View details →DOI: 10.1210/jcemcr/luac014.052
Negative / Null Result Report

No Introduction Necessary: Face-saving Answer Options Outperform Preambles in Reducing Social Desirability Bias

Emma Zaal, John Hoeks, Yfke Ongena · 2025 · Journal of Survey Statistics and Methodology

Abstract Social Desirability Bias (SDB), providing a favorable image of oneself in self-reports, is a persistent problem in survey research on sensitive topics. However, face-saving approaches appear promising in discouraging SDB.…

View details →DOI: 10.1093/jssam/smaf017
Negative / Null Result Report

Adrenal nodule: does computed tomography outperform chemical shift magnetic resonance imaging in differentiating benign versus malignant?

Noble Charles, Nilkanth Pal, Jeevan Vernekar · 2025 · African Journal of Urology

Abstract Background The radiologist faces the dilemma of characterizing adrenal lesions, especially in oncology patients, as this finding can alter the patient’s management and prognosis. The objectives of this study were (1) to evaluate…

View details →DOI: 10.1186/s12301-025-00499-6
Negative / Null Result ReportOpen accessNutrition. Foods and food supply

Effects of N-acetylcysteine on aging cell and obesity complications in obese adults: a randomized, double-blind clinical trial

Mohammad Hassan Sohouli, Ghazaleh Eslamian, Nasser Malekpour Alamdari et al. · 2023 · Frontiers in Nutrition

BackgroundWe decided to conduct this study with the aim of investigating the effects of N-Acetylcysteine (NAC) on obesity complications and senescence of visceral adipose tissue in obese adults.Methods and analysisThe present study was conducted as a randomized clinical trial (RCT) (Clinical trial registry number: IRCT20220727055563N1) on 40 obese adults candidates for bariatric surgery, who were randomly assigned to receive 600 mg of NAC (n = 20) or placebo as a control (n = 20) for 4 weeks. During bariatric surgery, visceral adipose tissue was used to examine gene expression and senescence c

View details →DOI: 10.3389/fnut.2023.1237869
Negative / Null Result Report

Later-generation epigenetic aging clocks outperform first-generation models in predicting survival in TCGA breast cancer

Xianglong Tan, Matteo Pellegrini, Su Yon Jung · 2026 · Clinical Epigenetics

Abstract Background Epigenetic aging bridges the gap between biological and chronological age by exploiting DNA methylation (DNAm) patterns. Over the past decade, successive DNAm-based clocks have been introduced, beginning with the…

View details →DOI: 10.1186/s13148-026-02102-3
Negative / Null Result Report

CT Radiomics Models Did Not Outperform Experts in Predicting [68Ga]Ga-PSMA-PET Positivity in Prostate Cancer Lymph Node Staging

Thula Cannon Walter-Rittel, Boris Gorodetski, Alexander Hartenstein et al. · 2026 · Current Oncology

Background: The use of [68Ga]Ga-PSMA-PET/CT for prostate cancer (PCa) staging is limited by cost and availability. This study evaluates whether radiomic features from contrast-enhanced (CE) CT can predict PSMA-positive lymph nodes (LNs) as…

View details →DOI: 10.3390/curroncol33030146
Negative / Null Result Report

Downstream Imaging Studies Do Not Significantly Improve Outcome in Most Patients with Chest Pain Who Did Not Reach Their Target Heart Rate on a Stress ECHO Study

Nativ Henkin, Ifat Karilker, Sergio L. Kobal et al. · 2023 · Journal of Clinical Medicine

Echocardiographic stress tests are often used to evaluate patients who complain of chest pain. However, some patients fail to reach the target heart rate required for the test to be conclusive (usually defined as 85% of the predicted…

View details →DOI: 10.3390/jcm12144832
Negative / Null Result ReportOpen accessPediatrics

The Relationship of Gonadotropin-releasing Hormone Agonists and Anthropometric Indices of Girls with Premature Idiopathic Central Precocious Puberty: A Cohort Study

Mohaddeseh Badpeyma, Roghayeh Molani-Gol, Fatemeh Sistanian et al. · 2024 · Iranian Journal of Neonatology

Background: This study aims to determine the effect of different GnRH agonist brands on body mass index (BMI), weight, and height in patients referred to the pediatric endocrinology clinic of Akbar Hospital.Methods: In this cohort study, 80 girls aged 5-8 years diagnosed with precocious puberty cases were included according to the Tanner staging and at the second puberty stage. The patients were classified into three groups of GnRH agonists, A, B, and C, receiving Diphereline, Microrelin, and Variopeptyl, respectively. Height, weight, and BMI were calculated every three months.Results: In grou

View details →DOI: 10.22038/ijn.2024.74125.2433
Negative / Null Result Report

Citrulline ingestion did not improve the age‐associated reduction in nitric oxide synthesis (698.6)

Il‐Young Kim, Scott Schutzler, Nicolaas Deutz et al. · 2014 · The FASEB Journal

A reduction in nitric oxide (NO) bioavailability that impairs peripheral blood flow regulation is a natural consequence of aging. Therefore , we investigated the effect of ingestion of citrulline, the precursor of arginine, on de novo…

View details →DOI: 10.1096/fasebj.28.1_supplement.698.6
Negative / Null Result Report

Double Stigma: The Influence of Race & Mental Health

Bobbie Call, null null, null null et al. · 2020 · John Heinrichs Scholarly & Creative Activities Day

Mental health stigma is prevalent and many people are affected all around the world (Watson, 2002). Stigma often prevents individuals with a mental illness from engaging in typical life routines (Corrigan, 2004). Individuals of ethnic…

View details →DOI: 10.58809/ccrp9120
Negative / Null Result Report

The Effects of Bisphenol A on Plant A

Michelle Storey, null null, null null et al. · 2020 · John Heinrichs Scholarly & Creative Activities Day

Bisphenol A (BPA) is a ubiquitous raw material used in the production of many everyday things such as food packaging and baby bottles. While there have been many studies about the effect that this can have on water and animals, there are…

View details →DOI: 10.58809/vacy9619
Negative / Null Result ReportOpen accessNeurology. Diseases of the nervous system

Efficacy analysis of mechanical thrombectomy combined with prolonged mild hypothermia in the treatment of acute middle cerebral artery occlusion: a single-center retrospective cohort study

Anqi Wang, Anqi Wang, Xuan Meng et al. · 2024 · Frontiers in Neurology

ObjectiveTo determine the efficacy of mechanical thrombectomy combined with prolonged mild hypothermia compared with conventional treatment in managing acute middle cerebral artery occlusion, and to explore whether extending the duration of hypothermia can improve neurological function.MethodFrom 2018 to June 2023, a retrospective analysis was conducted on 45 patients with acute middle cerebral artery occlusion treated at the NICU of Suzhou Kowloon Hospital, affiliated with Shanghai Jiao Tong University School of Medicine. After thrombectomy, patients were admitted to the neurological intensiv

View details →DOI: 10.3389/fneur.2024.1406293
Negative / Null Result Report

Engaging Students in Distance Learning Discussions

Dorothy Ochs, null null, null null et al. · 2022 · John Heinrichs Scholarly & Creative Activities Day

Purpose: The purpose of this poster is to explore various types of discussion formats in order to find ones that keep the students thoughtfully engaged and motivated. • Methods: The poster will compare and contrast several different types…

View details →DOI: 10.58809/mkeu5488
Negative / Null Result Report

Inflation Management In The Eu: Does The Eurozone Outperform Non-Euro States?

Anna Prucnal · 2025 · International Journal of Business & Management Studies

This study examines the effectiveness of the monetary policy of the European Central Bank (ECB) in managing inflation in the Euro Area compared to the independent monetary policy of seven European Union Member States outside the Economic…

View details →DOI: 10.56734/ijbms.v6n1a7