Negative / Null Result ReportMedicine
Mantovani, Chagas, Horiquini-Barbosa · 2026 · Developmental neurorehabilitation
Children diagnosed with central nervous system (CNS) tumors frequently present with persistent motor impairments that compromise independence and participation. Although the Gross Motor Function Measure (GMFM-88) is widely used in…
View details →DOI: 10.1080/17518423.2026.2679487 Negative / Null Result ReportMedicine
Yao, Mamone, Wu et al. · 2026 · Frontiers in psychology
Age-related declines in muscle strength are partly attributable to altered neural drive and agonist-antagonist coordination. This study aimed to evaluate the effects of motor imagery training (MIT) on maximal force production and…
View details →DOI: 10.3389/fpsyg.2026.1817866 Negative / Null Result ReportMedicine
Huang, Tsai, Lin et al. · 2026 · Taiwanese journal of obstetrics & gynecology
A higher oocyte yield is generally associated with improved outcomes in assisted reproductive technology (ART). Vitrification enables the accumulation of oocytes, zygotes, or embryos across multiple cycles, offering a potential strategy to…
View details →DOI: 10.1016/j.tjog.2025.06.010 Negative / Null Result ReportMedicine
Prajapati, Gupta, Mathew et al. · 2026 · The Indian journal of tuberculosis
Tuberculosis (TB) is a significant health issue in the world, and lack of health literacy has resulted in delayed care-seeking practices, non-compliance with treatment regimens, and subsequent stigma in communities with the infection. The…
View details →DOI: 10.1016/j.ijtb.2026.02.014 Negative / Null Result ReportMedicine
Riyapan, Laopran, Chantanakomes et al. · 2026 · Resuscitation
Dispatcher-assisted cardiopulmonary resuscitation (DA-CPR) has been shown to increase bystander CPR rates and improve outcomes after out-of-hospital cardiac arrest (OHCA). However, dispatchers cannot directly visualize the scene, which may…
View details →DOI: 10.1016/j.resuscitation.2026.111191 Negative / Null Result ReportMedicine
Trevethan, Doig, Patterson et al. · 2026 · Lymphology
ICG lymphography is a lymphatic imaging tool that can inform lymphedema treatment, including self-management. Self-management requires patient engagement in a multimodal treatment program. However, lack of knowledge about lymphedema,…
Negative / Null Result ReportMedicine
Zhang, Jiang, Jiang · 2026 · The journal of sexual medicine
Hypertension is a major cause of erectile dysfunction (ED). The impact of hypertension on the transcriptome and proteome of penile corpus cavernosum tissue, as well as its relationship with erectile dysfunction, is not clear. This study…
View details →DOI: 10.1093/jsxmed/qdag191 Negative / Null Result ReportMedicine
Tsiotsios, Vamvakas, Labropoulou et al. · 2026 · Acta haematologica
Introduction Patients with homozygous β-thalassemia show continuously improved survival, which has contributed to the development of kidney complications, predominantly expressed as increased albuminuria. In particular, patients with…
View details →DOI: 10.1159/000552285 Negative / Null Result ReportMedicine
Ani, Hameed · 2026 · Wiadomosci lekarskie (Warsaw, Poland : 1960)
Aim: This study aimed to evaluate the effectiveness of a structured intravenous infusion protocol in improving the quality of care and reducing IV-related complications among hospitalized patients. Materials and Methods: A purposive sample…
View details →DOI: 10.36740/wlek/219896 Negative / Null Result ReportMedicine
Chilundo, Xinavane, Huo et al. · 2026 · Frontiers in reproductive health
Despite national policies promoting adolescent- and youth-friendly health services, implementation gaps hinder improvements in adolescent sexual and reproductive health outcomes in Mozambique. S-NICE is a structured, participatory…
View details →DOI: 10.3389/frph.2026.1828528 Negative / Null Result ReportMedicine
Sheikh, Singh, Smith et al. · 2026 · Frontiers in cardiovascular medicine
The impact of catheter-directed thrombolysis (CDT), catheter-directed embolectomy (CDE) and surgical pulmonary embolectomy (SPE) on long term RV function among patients with acute PE remains unclear. We investigated the association of…
View details →DOI: 10.3389/fcvm.2026.1767184 Negative / Null Result ReportMedicine
Navidifar, Kaveh, Hosseini et al. · 2026 · Veterinary and animal science
Efficient estrus synchronization is important for improving reproductive performance in dairy herds; however, variations in ovarian activity among cows of different parities may influence responses to synchronization protocols. The present…
View details →DOI: 10.1016/j.vas.2026.100739 Failed Experiment ReportMedicine
Baier, Miao, Schirrmacher et al. · 2026 · Pharmaceuticals (Basel, Switzerland)
Background : Zirconium-89 ( 89 Zr) is a key PET radionuclide and the limited in vivo stability of its clinically used 89 Zr-DFO complexes has driven the pursuit of improved chelator architectures. Among these, DFO* has attracted particular…
View details →DOI: 10.3390/ph19060813 Negative / Null Result ReportOpen accessMedicine
Li H, Li X, Gao W et al. · 2026 · Frontiers in sports and active living
Background Basketball requires players to perform complex technical actions under conditions of dynamic instability. Traditional stability and strength training mainly improves muscle strength; however, it is often insufficient for…
View details →DOI: 10.3389/fspor.2026.1827231 Negative / Null Result ReportOpen accessMedicine
van Mourik M, Spierings J, Koca P et al. · 2026 · Journal of tissue engineering and regenerative medicine
Providing a functional pericellular matrix (PCM) by fine-tuning the microenvironment of the articular chondrocytes (ACs) can greatly improve the outcomes of articular cartilage tissue engineering. While harvesting ACs with their PCM…
View details →DOI: 10.1155/term/9947868 Negative / Null Result Report
Li F, Wang C, Fan X et al. · 2026 · Preprint
Abstract Objective The objective of this study was to evaluate the efficacy of acupuncture as an approach for improving visual function and to predict the long-term efficacy of this approach in controlling myopia progression. Methods…
View details →DOI: 10.21203/rs.3.rs-9724822/v1 Negative / Null Result ReportOpen accessMedicine
Raafat MH, Mourad KE, Elsyad MA · 2026 · BMC oral health
Background Reviewing the literature, the optimal implant position for 2-implant retained mandibular overdentures, which would be associated with improved peri-implant tissues, higher retention values, and better patient satisfaction,…
View details →DOI: 10.1186/s12903-026-08441-0 Negative / Null Result ReportOpen accessMedicine
Refai OM, Abdelfattah Mohamed AM, Ali El-Fiky AM · 2026 · BMC oral health
Background Mandibular complete dentures often lack stability, leading to prolonged occlusion and disocclusion times. Immediate-loading implant overdentures can improve functional control, but evidence comparing splinted and non-splinted…
View details →DOI: 10.1186/s12903-026-08855-w Negative / Null Result ReportOpen accessMedicine
Salim O, Chari A, Tahir MZ · 2026 · Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery
Purpose Hemispherotomy is an established treatment for children with drug-resistant epilepsy. Recent reports have suggested a superiority of outcomes with the vertical approach compared to the traditional lateral approach. This study…
View details →DOI: 10.1007/s00381-026-07353-2 Negative / Null Result ReportOpen accessMedicine
Bugacov H, Cusmai C, Li K et al. · 2026 · Transplant international : official journal of the European Society for Organ Transplantation
This study investigated acute rejection in ABO-compatible versus ABO-identical lung transplants from 2005-2023, with a secondary objective of comparing 5-year survival. Lung transplantation improves quality of life and survival; however,…
View details →DOI: 10.3389/ti.2026.15722 Negative / Null Result Report
Li S, Chai H, Bao W et al. · 2026 · Preprint
Abstract Background: It is commonly recommended to restore the mechanical axis to within –0° ± 3° in valgus knee. However, the situation is quite different when the alignment is –3° or 3° in the presence of a compromised MCL in Ranawat…
View details →DOI: 10.21203/rs.3.rs-9715753/v1 Negative / Null Result ReportOpen accessMedicine
Yan J, Feng L, Wu P et al. · 2026 · Animal nutrition (Zhongguo xu mu shou yi xue hui)
Taurine is a multifunctional feed additive that is abundant in fish meal but scarce in plant protein sources. The aim of this study was to investigate the effects of taurine supplementation in fish meal-free diet on sub-adult grass carp (…
View details →DOI: 10.1016/j.aninu.2025.10.016 Negative / Null Result ReportOpen accessMedicine
Gao J, Hu CC, Wang XY et al. · 2026 · Frontiers in medicine
Background Perinatal sleep disturbance is highly prevalent among women undergoing elective cesarean section. Dexmedetomidine has been proven effective in improving sleep quality in patients undergoing general surgery, and this study aimed…
View details →DOI: 10.3389/fmed.2026.1823100 Negative / Null Result ReportMedicine
Checchi V, Cavani F, Vistola M et al. · 2026 · Operative dentistry
Objective Single-shade materials are favored for simplifying clinical workflows without compromising the esthetics of restorations, although evidence supporting their use remains limited. Therefore, this laboratory evaluated color match of…
View details →DOI: 10.2341/24-114-l Negative / Null Result ReportOpen accessMedicine
Wei C, An J, Lin Y et al. · 2026 · PeerJ
Background Badminton is a physically demanding sport requiring a combination of aerobic endurance, anaerobic power, agility, and explosive strength. Repeated sprint training (RST) has emerged as a time-efficient strategy for improving…
View details →DOI: 10.7717/peerj.21111 Negative / Null Result ReportOpen accessAnesthesiology
Suborov Evgeny V, Smetkin Alexey A, Kondratiev Timofey V et al. · 2012 · BMC Anesthesiology
Abstract Background Mechanical ventilation with high tidal volumes may cause ventilator-induced lung injury (VILI) and enhanced generation of nitric oxide (NO). We demonstrated in sheep that pneumonectomy followed by injurious ventilation promotes pulmonary edema. We wished both to test the hypothesis that neuronal NOS (nNOS), which is distributed in airway epithelial and neuronal tissues, could be involved in the pathogenesis of VILI and we also aimed at investigating the influence of an inhibitor of nNOS on the course of VILI after pneumonectomy. Methods Anesthetized sheep underwent right pn
View details →DOI: 10.1186/1471-2253-12-10 Negative / Null Result ReportOpen accessMedicine
William Coley, Sree Rayavarapu, Jack H van der Meulen et al. · 2013 · PLoS ONE
BACKGROUND: Current treatments for idiopathic inflammatory myopathies (collectively called myositis) focus on the suppression of an autoimmune inflammatory response within the skeletal muscle. However, it has been observed that there is a poor correlation between the successful suppression of muscle inflammation and an improvement in muscle function. Some evidence in the literature suggests that metabolic abnormalities in the skeletal muscle underlie the weakness that continues despite successful immunosuppression. We have previously shown that decreased expression of a purine nucleotide cycle
View details →DOI: 10.1371/journal.pone.0065970 Negative / Null Result ReportOpen accessOphthalmology
V S Vijitha, Tarjani Vivek Dave, Somasheila I Murthy et al. · 2021 · Indian Journal of Ophthalmology
Purpose: To describe a series of sight-threatening ocular and adnexal involvement associated with dengue hemorrhagic fever and their treatment options. Methods: Retrospective, interventional, non-comparative case series. Medical records of patients who presented with ocular symptoms attributed to dengue hemorrhagic fever were reviewed. Demography, presenting features, and treatment outcomes were recorded. Outcome measures assessed included globe salvage, vision salvage, and visual improvement. The outcome was deemed as favorable if vision salvage was possible and unfavorable if the vision was
View details →DOI: 10.4103/ijo.ijo_1588_20 Negative / Null Result ReportOpen accessPublic aspects of medicine
Rob Horne, Caroline Sabin, Trudie Chalder et al. · 2025 · Programme Grants for Applied Research
Background Antiretroviral therapy has transformed human immunodeficiency virus infection intoa chronic condition associated with normal life expectancy. In the United Kingdom, the uptake of antiretroviral therapy is generally high, but a delay in starting antiretroviral therapy and non-adherence compromise the health and well-being of people living with human immunodeficiency virus, increase the risk of transmission of human immunodeficiency virus and increase National Health Service costs. Objectives The overall aim was to improve antiretroviral therapy uptake and adherence by addressing perc
View details →DOI: 10.3310/kppw8401 Negative / Null Result ReportOpen accessTherapeutics. Pharmacology
Wang J, Lu S, Zhang C et al. · 2025 · Drug Design, Development and Therapy
Jinglong Wang, Shijia Lu, Chenxiao Zhang, Junjie Wang, Huiru Wu, Guofei Li Department of Pharmacy, Shengjing Hospital of China Medical University, Shenyang, Liaoning Province, People’s Republic of ChinaCorrespondence: Guofei Li, Department of Pharmacy, Shengjing Hospital of China Medical University, No. 36, Sanhao Street, Shenyang, 110004, People’s Republic of China, Tel/Fax +86-24-23925108, Email sylgf2009@163.comPropose: The co-treatment of ulcerative colitis with berberine hydrochloride (BBR), the Janus kinase(JAK) inhibitor Tofacitinib (TOFA), and Fligotinib (FIGA) is feasible and sophisti
