A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.
1761 results in Negative / Null Result Report for "Mpro" · page 34 of 59
Dauder-Bosch E, Martin-Martinez JM · 2025 · Preprint
Room temperature self-healing polyurethanes (PUs) generally showed limited mechanical properties. In order to improve the mechanical properties of PUs without sacrificing their self-healing ability, in this study, different amounts of…
Saravia DH, Silvan YA, Martinez JI · 2025 · Preprint
Abstract Despite similar rates of mental illness, non-Latinx Whites received care at higher rates compared to Latinxs (NIMH, 2024). Latinx adults report lower mental health literacy (MHL) and higher stigma compared to NLW, which can…
Kawata S, Hiramatsu Y, Honke J et al. · 2026 · Annals of surgical oncology
Background Esophagectomy confers high postoperative morbidity and mortality. To improve postoperative outcomes, this study investigated the effectiveness of a 2-week prehabilitation program on the preoperative cardiopulmonary function of…
Payne V, Hall M, Johnson MJ · 2025 · Archives of disease in childhood. Fetal and neonatal edition
Objective To investigate the effect of alcohol-impregnated port protectors (AIPPs) on neonatal central line-associated bloodstream infection (CLABSI) rates. Design A quality improvement study. Setting A tertiary neonatal unit in the UK.…
Ferreira RD, Faleiros Ferreira CH, Gonçalves-Ferri WA · 2025 · Preprint
Background Inhaled nitric oxide (iNO) is a standard treatment for neonatal pulmonary hypertension in high-resource settings. Yet, its efficacy and cost-effectiveness in low- and middle-income countries (LMICs) remain underexplored. This…
Lorigan P, Medina TM, Nyakas M et al. · 2026 · European journal of cancer (Oxford, England : 1990)
Purpose Immune checkpoint inhibitor (ICI) combinations have improved outcomes in patients with advanced melanoma; however, long term survival remains poor. The addition of therapeutic cancer vaccines to ICI combinations represents a…
López-Campos Ó, Chabot B, Attema HR et al. · 2025 · Meat Science.
The effect of localized low voltage electrical stimulation (LVES, 45 V) on meat quality and palatability of the longissimus thoracis et lumborum (LTL) and semitendinosus (ST) was evaluated in this study. There were stimulation method ×…
Miller ZE, Digirolamo SJ, Molnar J et al. · 2026 · Pediatric quality & safety
Introduction Emergency department evaluations for acute child sexual assault include anogenital photodocumentation as a standard of care, which has implications for accurate clinical care and forensic significance. If photodocumentation…
Zhang S, Jia B, Huang W et al. · 2025 · ACS nano
The toxicity of negatively charged nanoplastics (NNP) to bacteria is generally subtler than that of positively charged counterparts, owing to limited NNP-cell interaction. This study hypothesized that common environmental cations (Na + ,…
Leong JWK, Lee BH, Haniball J et al. · 2025 · Journal of clinical orthopaedics and trauma
Background Achieving a neutral mechanical axis alignment (MAA) in Total Knee Arthroplasty (TKA) is associated with increased implant longevity and patient satisfaction, and robot-assisted (robotic) TKA is touted to improve implant…
Giamarellos-Bourboulis EJ, Jemec GBE, Prens EP et al. · 2026 · The British journal of dermatology
Background The results of a previous phase IIa trial suggested efficacy of the anti-C5a compound vilobelimab in a small number of patients with severe hidradenitis suppurativa (HS) refractory to adalimumab treatment. Objectives To study…
Williams EA, Ogden R, Stewart AJ et al. · 2025 · Preprint
Trains of auditory clicks increase subsequent judgements of stimulus duration by approximately 10%. Scalar timing theory suggests this is due to a 10% increase in pacemaker rate, a main component of the internal clock. The effect has been…
Brown AE, Marostica CW, Martini WA · 2026 · Journal of personalized medicine
Background/Objectives: Machine learning (ML) models can predict hospital admission from emergency department (ED) triage data with areas under the receiver operating characteristic curve (AUC) exceeding 0.85. Whether incorporating the…
Lantian A, Rose M · 2024 · Scandinavian journal of psychology
Transhumanism is a movement that emphasizes the improvement of the human condition by developing technologies and making them widely available. Conspiracy theories regularly refer to the allegedly transhumanist agenda of elites. We…
Schell C, Godinho A, Cunningham JA · 2026 · Substance abuse treatment, prevention, and policy
BACKGROUND: Invitation letters can be the first point of contact between research staff and potential participants and a number of modifiable variables have been studied to improve their effectiveness. The aim of this analysis was to…
Kipping R, Anne Simpson S, Hannam K et al. · 2026 · The Lancet regional health. Europe
Background Early childhood education and care (ECEC) provision is widespread. NAPSACC UK is an intervention in ECECs designed to improve nutrition and physical activity policies, practice and provision through ECEC staff workshops,…
Singstock M, Abdul Khader AHS, Wayant C et al. · 2026 · The oncologist
Background Oncology clinical trials, regardless of success in meeting their primary endpoint, often suffer from spin-the misrepresentation of research findings. Despite dramatic improvements in myeloma outcomes, numerous recent myeloma…
Nakata Y, Watanabe Y, Ozaki A · 2026 · Cureus
Background The purpose of this study was to evaluate whether the workstyle reform, aimed at improving physician health and safety, achieved a secondary goal of enhancing surgical productivity by applying the Malmquist Index (MI) model. We…
Lantian A, Rose M · 2021 · Preprint
Introduction. Transhumanism is a movement that emphasizes the improvement of the human condition by developing technologies and making them widely available. Conspiracy theories regularly refer to the allegedly transhumanist agenda of…
Williams EA, Ogden R, Stewart AJ et al. · 2021 · Preprint
Trains of auditory clicks increase subsequent judgements of stimulus duration by approximately 10%. Scalar timing theory suggests this is due to a 10% increase in pacemaker rate, a main component of the internal clock. The effect has been…
Schiff KJ, Schiff DS, Moy BJ et al. · 2025 · PNAS nexus
Does the implementation of external oversight in policing improve public perceptions of police legitimacy? Civilian review boards (CRBs) are frequently promoted as mechanisms to enhance the legitimacy of police agencies by providing…
Li J, Jin T, Chi Y et al. · 2025 · Neuropsychiatric disease and treatment
Purpose Reducing electroconvulsive therapy (ECT)'s cognitive burden without compromising efficacy is critical. Although magnetic seizure therapy (MST) shows comparable symptom remission in schizophrenia, its neuroanatomical…
Fohrmann D, Schaffarczyk M, Menge C et al. · 2026 · Sports medicine - open
Background Advanced footwear technology (AFT) can enhance long-distance running performance by improving running economy (RE). However, the range of the individual improvements is large. Different intra-individual responses in running…
Yoshikawa N, Masaki H · 2021 · Frontiers in psychology
Previous studies have shown that viewing cute pictures leads to performance improvement in a subsequent fine motor task. We examined the beneficial effects of viewing cute pictures in a more complex sporting skill (i.e., basketball free…
Diarra NH, Dicko Y, Roschnik N et al. · 2025 · Maternal & child nutrition
A cluster-randomised controlled trial was conducted in 60 communities in southern Mali to evaluate the impact of micronutrient powders (MNP) combined with seasonal malaria chemoprevention (SMC) on anaemia (primary endpoint), Plasmodium…
Berks JW, Williams MN · 2026 · Europe's journal of psychology
According to creative writing experts, adding conflict to dialogue improves story quality and audience reaction to that story. This idea draws from the widely held theory that conflict is vital for dramatic stories. Yet despite conflict's…
Hu G, Woodman GF · 2024 · Visual cognition
Previous research suggests that applying anodal transcranial direct-current stimulation (tDCS) to the medial-frontal cortex can improve how quickly subjects learn to make simple discriminations (i.e., red from blue). Here, we tested the…
Radovich E, Karki S, Das S et al. · 2024 · Preprint
Background Understanding implementation fidelity, or adherence to the intervention-as-intended, is essential to interpreting the results of evaluations. In this paper, we propose a longitudinal, explanatory approach to implementation…
Lara-Arevalo J, Corvalan C, Pemjean I et al. · 2025 · Advances in nutrition (Bethesda, Md.)
Healthy food voucher programs (HFVPs) provide lower-income participants with benefits to purchase healthy, nutrient-dense foods and are a promising strategy for improving dietary and nutritional outcomes. HFVPs can complement policies…
Castellano Bueno J, Paraskevopoulou A, Miller CW et al. · 2025 · Preprint
Fluid control protocols are widely used in neuroscience to motivate laboratory macaques to engage with behavioural tasks. Despite strong evidence that the physiology of the animals is not compromised by such protocols, fluid control…