Oral Peanut Immunotherapy With Butyrate Adjuvant (OPIA) in Children: A Randomised, Controlled Trial.
Hsu PS; Barnes EH; Barnes M; McArthur M; Valerio C; Santner-Nanan B; Pinget G; Wang Y · 2025 · Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
Background Sustained unresponsiveness (SU) remains a major challenge for peanut OIT. The short chain fatty acid (SCFA) butyrate has the potential to upregulate regulatory T cells (Tregs) to improve long term tolerance. We conducted a…
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Metadata source: Europe PMC · DOI 10.1111/cea.70127