Negative / Null Result Report
Wilkening J, Jungeblut HM, Adamovic I et al. · 2025 · Preprint
Intermittent theta burst stimulation (iTBS) is a promising non-invasive treatment for major depressive disorder (MDD), though significant variability exists in patient responses. This quadruple-blind, sham-controlled crossover randomized…
View details →DOI: 10.1101/2025.04.06.25325324 Negative / Null Result Report
Litman M, Azarpeykan S, Hood RJ et al. · 2025 · Preprint
In patients with ischaemic stroke, retrograde perfusion of the penumbra by the leptomeningeal collateral vessels (LMCs) is a strong predictor of clinical outcome, thus raising the possibility that enhancing LMC flow could offer a novel…
View details →DOI: 10.1101/2025.03.25.644833 Negative / Null Result ReportOpen accessMedicine
Santoro E, Broockman DE, Kalla JL et al. · 2025 · Proceedings of the National Academy of Sciences of the United States of America
Scholars and practitioners widely posit that listening to other people enhances efforts to persuade them. Listening may enhance persuasion by promoting cognitive processing, reducing defensiveness, and improving perceptions of the…
View details →DOI: 10.1073/pnas.2421982122 Negative / Null Result ReportMedicine
Viriyarattanasak C, Takemura Y, Hashimoto T et al. · 2025 · Journal of the science of food and agriculture
Background Softening of winter-harvested frozen broccoli is a challenge. Application of boron (B) can improve fruit texture, but its effects on processed vegetables remain unexplored. This study is the first to investigate the impact of…
View details →DOI: 10.1002/jsfa.14249 Negative / Null Result ReportOpen accessMedicine
Borgognoni AB, Freund SS, Baas J et al. · 2026 · Frontiers in surgery
Introduction Early osseointegration is essential for the long-term success of uncemented custom-made prostheses, particularly in oncologic bone reconstruction where bone stock is compromised. Strontium (Sr) has demonstrated osteogenic…
View details →DOI: 10.3389/fsurg.2026.1818358 Negative / Null Result ReportMedicine
Hsu PS, Barnes EH, Barnes M et al. · 2025 · Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology
Background Sustained unresponsiveness (SU) remains a major challenge for peanut OIT. The short chain fatty acid (SCFA) butyrate has the potential to upregulate regulatory T cells (Tregs) to improve long term tolerance. We conducted a…
View details →DOI: 10.1111/cea.70127 Negative / Null Result ReportOpen accessMedicine
Lyu A, Mungalsingh MA, Silva AE et al. · 2026 · Investigative ophthalmology & visual science
Purpose Macular degeneration impairs central vision, compelling patients to use their peripheral vision for reading, which is difficult due to reduced spatial resolution and crowding. Although perceptual learning improves reading,…
View details →DOI: 10.1167/iovs.67.1.16 Negative / Null Result ReportMedicine
Ghazzagh A, Naderi A, Agha-Alinejad H et al. · 2025 · International journal of sport nutrition and exercise metabolism
Taurine (TAU) has been shown to improve time to exhaustion (TTE) and fat oxidation during exercise; however, no studies have examined the effect of acute TAU supplementation on maximal fat oxidation (MFO) and related intensity to MFO…
View details →DOI: 10.1123/ijsnem.2024-0076 Negative / Null Result ReportMedicine
Fawzy M, Elsuity MA, Magdi Y et al. · 2025 · BJOG : an international journal of obstetrics and gynaecology
Background Artificial oocyte activation (AOA) is used to improve fertilisation rates in intracytoplasmic sperm injection (ICSI) cycles. Objectives To assess the effectiveness of AOA on fertilisation, embryo development, and clinical…
View details →DOI: 10.1111/1471-0528.18085 Negative / Null Result ReportOpen accessMedicine
Lu Y, Sun P, Jin H et al. · 2025 · Neurology and therapy
Introduction Ischemic stroke is the second leading cause of mortality and a major contributor to disability worldwide. Hospital length of stay (LOS) is a marker of medical efficiency for stroke care. There is limited information on this…
View details →DOI: 10.1007/s40120-025-00712-2 Negative / Null Result ReportMedicine
Jung SH, Jung M, Chung K et al. · 2025 · Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association
Purpose To compare the patient-reported outcome (PRO) improvements and cartilage status of trochlear cartilage defects (TCDs) after additional arthroscopic microdrilling versus no treatment for TCDs during medial open-wedge high tibial…
View details →DOI: 10.1016/j.arthro.2025.01.009 Negative / Null Result ReportMedicine
Martín-Olmedo JJ, Miras-Moreno S, Cuadra-Montes K et al. · 2025 · International journal of sport nutrition and exercise metabolism
L-citrulline (CIT) supplementation seems to improve resistance training performance; yet, whether malate has additive ergogenic effects when combined with CIT is unknown. This randomized, double-blind, placebo-controlled crossover trial…
View details →DOI: 10.1123/ijsnem.2024-0006 Negative / Null Result ReportOpen accessMedicine
Kasai N, Hayashi K, Kito M et al. · 2025 · Physical activity and nutrition
Purpose Piceatannol, a polyphenolic compound found in high concentrations in passion fruit, has been reported to exert multiple physiological effects in preclinical studies, including vascular relaxation and increased expression of…
View details →DOI: 10.20463/pan.2025.0034 Negative / Null Result ReportMedicine
Yang N, Subak LL, Shatkin-Margolis A et al. · 2026 · Urogynecology (Philadelphia, Pa.)
Importance Urinary incontinence (UI) can negatively affect sexual function in women. Although many women with UI seek complementary strategies such as pelvic floor yoga techniques to improve sexual functioning, evidence of their efficacy…
View details →DOI: 10.1097/spv.0000000000001705 Negative / Null Result ReportMedicine
Naemura N, Fukuda Y · 2026 · [Nihon koshu eisei zasshi] Japanese journal of public health
Objectives Improving the screening rates in specific health checkups and guidance represents a challenge for health insurance providers and local governments nationwide. In this study, we evaluated SMS-based health checkup encouragement…
View details →DOI: 10.11236/jph.25-133 Negative / Null Result Report
Xia C, Yang R, Ou S et al. · 2026 · Preprint
Abstract Background Robotic-assisted unicompartmental knee arthroplasty (RA-UKA) improves component alignment; however, improved radiographic precision does not consistently translate into superior clinical outcomes. Nutritional status may…
View details →DOI: 10.21203/rs.3.rs-9052959/v1 Negative / Null Result ReportMedicine
van der Meulen LWJ, Bergmans ME, Assil S et al. · 2026 · British journal of clinical pharmacology
Aim Recovering dysbiosis may improve atopic dermatitis (AD) symptoms. XZ.700 is a recombinant chimeric endolysin that specifically targets Staphylococcus aureus and could be a new treatment option for patients with AD. The aim of this…
View details →DOI: 10.1002/bcp.70630 Negative / Null Result ReportMedicine
Murray AL, Dryburgh K, Sonuga-Barke EJS · 2026 · Journal of attention disorders
Objective ADHD and internalising symptoms such as anxiety and depression are known to be associated in adolescence and understanding the mechanisms linking them is important for improving mental health outcomes for adolescents with ADHD…
View details →DOI: 10.1177/10870547261419589 Negative / Null Result ReportMedicine
Van Epps VM, Daur-Schierholz M, Dortenzio M et al. · 2026 · International journal of speech-language pathology
Purpose This pragmatic clinical trial examined the functional impact of a modified speech-language pathology intervention delivery model (including telepractice, reduced therapy frequency, and emphasised home programmes with parent…
View details →DOI: 10.1080/17549507.2026.2630835 Negative / Null Result ReportMedicine
Saravia DH, Silvan YA, Martinez JI · 2026 · Community mental health journal
Despite similar rates of mental illness, non-Latinx Whites (NLW) received care at higher rates compared to Latinxs (National Institute of Mental Health, 2024). Latinx adults report lower mental health literacy (MHL) and higher stigma…
View details →DOI: 10.1007/s10597-025-01584-4 Negative / Null Result ReportMedicine
Rodrigo-Carranza V, Alda-Blanco A, Kuzmeski J et al. · 2026 · International journal of sports physiology and performance
Purpose The mechanisms behind improvements in running economy (RE) from shoes with supercritical foams (SCF) compared with a traditional midsole material (ethylene vinyl acetate [EVA]) remain only partially understood. This study aimed to…
View details →DOI: 10.1123/ijspp.2025-0475 Negative / Null Result ReportOpen accessMedicine
Glass-Biran AH, Eyre A, Stein G et al. · 2026 · BMJ open quality
Objective To evaluate whether adding a fourth physician to the emergency department night shift would improve metrics. Methods This retrospective cohort study used data from the Meir Medical Centre emergency department, 1 January 2021 to…
View details →DOI: 10.1136/bmjoq-2025-003648 Negative / Null Result ReportMedicine
Chew BMH, Lim SSA, Gan TRX et al. · 2026 · Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery
Objective There is increasing use of intraoperative parathyroid hormone (ioPTH) in minimally invasive parathyroidectomy (MIP). While ioPTH has improved cure rate, there is little evidence to suggest effectiveness in primary…
View details →DOI: 10.1002/ohn.70218 Negative / Null Result ReportMedicine
Li L, Gao S, Zhu H et al. · 2026 · European journal of obstetrics, gynecology, and reproductive biology
Introduction Frozen embryo transfer offers improved cumulative pregnancy rates and reduces complications compared to fresh cycles. Successful outcomes depend on both embryonic potential and endometrial receptivity, necessitating…
View details →DOI: 10.1016/j.ejogrb.2026.115194 Negative / Null Result ReportMedicine
Min Y, Wanyan X, Liu S et al. · 2025 · Ergonomics
This study proposes a network-based training strategy to improve the team situation awareness (TSA) of crews in complex socio-technical systems. Eighty-four participants were recruited and divided into twenty-one teams to receive different…
View details →DOI: 10.1080/00140139.2025.2538703 Negative / Null Result ReportOpen accessMedicine
Kim B, Boustany C, Fethney J et al. · 2026 · Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer
Purpose This study aimed to report the incidence, common reasons, and associated risk factors for unplanned hospital presentations during chemotherapy treatment. Methods A secondary analysis using data from a randomized controlled trial…
View details →DOI: 10.1007/s00520-026-10510-7 Negative / Null Result ReportMedicine
Janssen JC, Schurink AW, Verhoef C et al. · 2026 · European journal of cancer (Oxford, England : 1990)
Background Adjuvant systemic therapy for resected stage III melanoma was introduced in clinical practice following the improved recurrence free survival in randomized controlled trials. However, after ten years of follow-up, adjuvant…
View details →DOI: 10.1016/j.ejca.2025.116202 Negative / Null Result ReportMedicine
Chovi-Trull M, Megías-Vericat JE, Palanques-Pastor T et al. · 2026 · Thrombosis research
Introduction Extended half-life factor IX concentrates (FIX-EHL) have been shown to improve clinical outcomes and reduce treatment burden in patients with hemophilia B (HB). Objectives To analyze the differences in pharmacokinetic (PK) and…
View details →DOI: 10.1016/j.thromres.2025.109580 Negative / Null Result Report
Dauder-Bosch E, Martin-Martinez JM · 2025 · Preprint
Room temperature self-healing polyurethanes (PUs) generally showed limited mechanical properties. In order to improve the mechanical properties of PUs without sacrificing their self-healing ability, in this study, different amounts of…
View details →DOI: 10.20944/preprints202508.2114.v1 Negative / Null Result Report
Saravia DH, Silvan YA, Martinez JI · 2025 · Preprint
Abstract Despite similar rates of mental illness, non-Latinx Whites received care at higher rates compared to Latinxs (NIMH, 2024). Latinx adults report lower mental health literacy (MHL) and higher stigma compared to NLW, which can…
View details →DOI: 10.21203/rs.3.rs-7444634/v1 