Failed Experiment ReportOpen accessComputer Science
D. Kiderlen, P. Danielewicz · 1996 · arXiv
Generalization of Gaussian trial wave functions in quantum molecular dynamics models is introduced, which allows for long-range correlations characteristic for composite nuclear fragments. We demonstrate a significant improvement in the description of light fragments with correlations. Utilizing either type of Gaussian wave functions, with or without correlations, however, we find that we cannot describe fragment formation in a dynamic situation. Composite fragments are only produced in simulations if they are present as clusters in the substructure of original nuclei. The difficulty is traced
Failed Experiment ReportOpen accessComputer Science
P. Danielewicz, D. Kiderlen · 1997 · arXiv
Generalization of Gaussian trial wave functions in quantum molecular dynamics models is introduced, which allows for long-range correlations characteristic for composite nuclear fragments. We demonstrate a significant improvement in the description of light fragments with the correlations. Utilizing either type of Gaussian wave functions, with or without correlations, however, we find that we cannot describe fragment formation in a dynamic situation. Composite fragments are only produced in simulations if these fragments are present as clusters in the substructure of original nuclei. The diffi
Failed Experiment ReportOpen accessComputer Science
Adeel Mahmood, Aaron B. Wagner · 2024 · arXiv
Channel coding for discrete memoryless channels (DMCs) with mean and variance cost constraints has been recently introduced. We show that there is an improvement in coding performance due to cost variability, both with and without feedback. We demonstrate this improvement over the traditional almost-sure (per-codeword) cost constraint that prohibits any cost variation above a fixed threshold. Our result simultaneously shows that feedback does not improve the second-order coding rate of simple-dispersion DMCs under the almost-sure cost constraint. This finding parallels similar results for unco
Failed Experiment ReportOpen accessTherapeutics. Pharmacology
Girish Parthan, Shobhit Bhansali, Anura V. Kurpad et al. · 2018 · BMC Pharmacology and Toxicology
Abstract Background Dipeptidyl peptidase 4 (DPP4) inhibitors improve glycemic control by promoting GLP1-mediated glucose-dependent insulin secretion and suppression of glucagon. Sitagliptin and vildagliptin have been shown to improve insulin sensitivity in patients with type 2 diabetes mellitus (T2DM). However, these patients had uncontrolled blood glucose at inclusion; therefore, the improvement in insulin sensitivity observed in these studies could be attributed to the drug per se and/or reduction in glucotoxicity. This study examines the effect of linagliptin on insulin sensitivity and β-ce
View details →DOI: 10.1186/s40360-018-0228-z Failed Experiment Report
Mrityunjoy Hazra, Ashok Kumar Singh · 2023 · International Journal of Engineering Materials and Manufacture
Present work describes the metallurgical failure investigation of a failed towing arm/bar. Aircraft attached with this incident travelled a distance of 2 km with normal towing speed (8 km/hr). The component is said to have broken while…
View details →DOI: 10.26776/ijemm.08.03.2023.01 Failed Experiment ReportOpen accessMedical physics. Medical radiology. Nuclear medicine
Ma Li, Men Yu, Feng Lingling et al. · 2019 · Radiology and Oncology
The mainstay therapy for locally advanced non-small cell lung cancer is concurrent chemoradiotherapy. Loco-regional recurrence constitutes the predominant failure patterns. Previous studies confirmed the relationship between increased biological equivalent doses and improved overall survival. However, the large randomized phase III study, RTOG 0617, failed to demonstrate the benefit of dose-escalation to 74 Gy compared with 60 Gy by simply increasing fraction numbers.
View details →DOI: 10.2478/raon-2019-0006 Failed Experiment ReportMedicine
Zeidan AM, Aakko S, Stahl M et al. · 2026 · Expert review of anticancer therapy
Introduction Higher-risk myelodysplastic syndromes (HR-MDS) remain an area of high unmet need in which multiple randomized late-stage trials have failed to improve outcomes beyond hypomethylating agent monotherapy, despite encouraging…
View details →DOI: 10.1080/14737140.2026.2640238 Failed Experiment ReportMedicine
Olluri A · 2025 · Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia
Experimental drugs lowering brain tau are heralded as improvements in the treatment of Alzheimer's disease. However, the outcomes in clinical trials testing these agents have consistently failed to improve patient outcomes, i.e. slow down…
View details →DOI: 10.1016/j.jocn.2025.111101 Failed Experiment ReportMedicine
Barakzie A, Jansen AJG, Cavalcante F et al. · 2025 · Journal of thrombosis and haemostasis : JTH
Background Intravenous thrombolysis (IVT) using recombinant tissue plasminogen activator prior to endovascular thrombectomy treatment (EVT) failed to improve treatment effect in acute ischemic stroke (AIS) patients compared with EVT alone.…
View details →DOI: 10.1016/j.jtha.2024.10.008 Failed Experiment ReportOpen accessComputer Science
Tilman Plehn, Michael Spannowsky, Michihisa Takeuchi · 2011 · arXiv
In time for the first tests on LHC data we introduce a set of improvements and tests of purely kinematic top tagging algorithms. First, we show how different jet algorithms can be used for different transverse momentum regimes. Combining pruning and filtering in the reconstruction can enhance the signal over background ratio significantly, while larger jet radii only give minor improvements. Finally, bottom tagging can be added to the top tagger, but at least for the HEPTopTagger does not improve the kinematic selection algorithm.
Failed Experiment ReportOpen accessComputer Science
Xinzhe Chen, Jianjiang Li · 2023 · arXiv
The escalating surge in data generation presents formidable challenges to information technology, necessitating advancements in storage, retrieval, and utilization. With the proliferation of artificial intelligence and big data, the "Data Age 2025" report forecasts an exponential increase in global data production. The escalating data volumes raise concerns about efficient data processing. The paper addresses the predicament of achieving a lower compression ratio while maintaining or surpassing the compression performance of state-of-the-art techniques. This paper introduces a lossy compressio
Failed Experiment ReportOpen accessComputer Science
Carmine Abate, Arthur Azevedo de Amorim, Roberto Blanco et al. · 2018 · arXiv
We propose a new formal criterion for evaluating secure compilation schemes for unsafe languages, expressing end-to-end security guarantees for software components that may become compromised after encountering undefined behavior---for example, by accessing an array out of bounds. Our criterion is the first to model dynamic compromise in a system of mutually distrustful components with clearly specified privileges. It articulates how each component should be protected from all the others---in particular, from components that have encountered undefined behavior and become compromised. Each comp
Failed Experiment ReportOpen accessPhysics
Ying-Dan Wang, Xiao-Bo Yan, Stefano Chesi · 2016 · arXiv
Using a perturbative treatment, we quantify the influence of non-adiabatic leakage and system dissipation on the transfer fidelity of a stimulated Raman adiabatic passage (STIRAP) process. We find that, optimizing transfer time rather than coupling profiles, leads to a significant improvement of the transfer fidelity. The upper bound of the fidelity has been found as a simple analytical function of system cooperativities. We also provide a systematic approach to reach this upper bound efficiently.
Failed Experiment ReportOpen accessComputer Science
V. Vedral · 1999 · arXiv
We investigate asymptotic distillation of entanglement in the presence of an unlimited amount of bound entanglement for bi-partite systems. We show that the distillability is still bounded by the relative entropy of entanglement. This offers a strong support to the fact that bound entanglement does not improve distillation of entanglement.
Failed Experiment ReportOpen accessComputer Science
J. A. Casas, A. Lleyda, C. Muñoz · 1996 · arXiv
The general constraints on the parameter space of soft-breaking terms, in order to avoid dangerous charge and color breaking minima, are applied to the four-dimensional string scenario where the dilaton is the source of supersymmetry breaking (dilaton-dominated limit). The results indicate that the whole parameter space is excluded on these grounds after imposing the present experimental data on the top mass. The inclusion of a non-vanishing cosmological constant does not improve essentially the prospects. Possible way-outs to this situation are briefly discussed.
Failed Experiment ReportOpen accessComputer Science
Henrique K. Miyamoto, Sheng Yang · 2026 · arXiv
This paper studies random-coding error exponents of randomised list decoding, in which the decoder randomly selects $L$ messages with probabilities proportional to the decoding metric of the codewords. The exponents (or bounds) are given for mismatched, and then particularised to matched and universal decoding metrics. Two regimes are studied: for fixed list size, we derive an ensemble-tight random-coding error exponent, and show that, for the matched metric, it does not improve the error exponent of ordinary decoding. For list sizes growing exponentially with the block-length, we provide a no
Failed Experiment ReportOpen accessMathematics
Anh-Huy Phan, Petr Tichavský, Andrzej Cichocki · 2017 · arXiv
In CANDECOMP/PARAFAC tensor decomposition, degeneracy often occurs in some difficult scenarios, e.g., when the rank exceeds the tensor dimension, or when the loading components are highly collinear in several or all modes, or when CPD does not have an optimal solution. In such the cases, norms of some rank-1 terms become significantly large and cancel each other. This makes algorithms getting stuck in local minima while running a huge number of iterations does not improve the decomposition. In this paper, we propose an error preservation correction method to deal with such problem. Our aim is
Failed Experiment Report
Liudmila Zakharova, Hikmet Nural, James R Nimlos et al. · 2013 · Circulation Research
A pilot clinical study using autologous c-Kit+ cells showed improvement in cardiac functions in congestive heart failure (CHF), however, it is unclear if c-Kit+ cells isolated from CHF hearts are equally as potent as cells from controls.…
View details →DOI: 10.1161/res.113.suppl_1.a131 