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Failure-mode index

Search what already failed

A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.

776 results for "aging" · page 26 of 26

Negative / Null Result ReportMedicine

Two-year prospective natural history study of EYS-associated retinitis pigmentosa using adaptive optics: the KEYS study.

Masakazu H, Akiko M, Midori Y et al. · 2026 · Scientific reports

This study was conducted to evaluate the longitudinal morphological changes in cone density (CD) in patients with the eyes shut homolog (EYS)-associated retinitis pigmentosa (RP) using adaptive optics (AO) fundus imaging and to assess its…

View details →DOI: 10.1038/s41598-026-56837-3
Negative / Null Result ReportOpen accessMedicine

Evaluation of Differences in Imaging Findings on Stress-MRI in Throwing Athletes With and Without a History of Ulnar Collateral Ligament Reconstruction.

Patel M, Schwartz K, Schenk M et al. · 2026 · Orthopaedic journal of sports medicine

Background Ulnar collateral ligament (UCL) reconstruction (UCLR) of the elbow is common in throwing athletes and reliably allows return to play. The literature supports stress imaging of the elbow to evaluate the integrity of the UCL. The…

View details →DOI: 10.1177/23259671261453313
Negative / Null Result ReportOpen accessMedicine

Engaging with Facebook Health Support Groups among Australian Culturally and Linguistically Diverse Populations.

Zein MMA, Win KT, Alananzeh I · 2026 · Healthcare informatics research

Objectives This study aims to explore the key factors that enhance engagement in Facebook health support groups among Australian culturally and linguistically diverse (CALD) communities. Methods A cross-sectional online survey was…

View details →DOI: 10.4258/hir.2026.32.1.14
Negative / Null Result Report

Assessing the Impact of Hard Palate Inclination, Concha Bullosa, and Nasal Septum Deviation on Maxillary Sinus Volume Using CBCT Imaging

Moradi A, Mohajeri Y, nikoo F · 2026 · Preprint

Abstract Objective: This study examines how maxillary sinus volume is influenced by factors such as nasal septum deviation, hard palate shift, and the presence of concha bullosa, considering the sinus’s close anatomical relationship with…

View details →DOI: 10.21203/rs.3.rs-8120446/v1
Failed Experiment ReportMedicine

Investigation of the relationship between background parenchymal enhancement and breast cancer using 3.0 Tesla magnetic resonance imaging.

Sekmen S, Hursoy N, Panc K et al. · 2026 · Clinical imaging

Aim This study aims to explore the correlation between background parenchymal enhancement (BPE) observed in breast magnetic resonance imaging (MRI) and the presence of breast cancer. Materials and methods A total of 761 patients (326…

View details →DOI: 10.1016/j.clinimag.2025.110680
Negative / Null Result ReportOpen accessMedicine

A Retrospective Study of the Presentation, Imaging Findings, and Outcomes in 195 Patients with Maxillofacial Fractures Treated with Closed Reduction or Open Reduction with Internal Fixation.

Durmuş Hİ, Polat ME · 2025 · Medical science monitor : international medical journal of experimental and clinical research

BACKGROUND Maxillofacial fractures represent one of the most common forms of traumatic injuries, affecting both function and aesthetics, and are associated with significant morbidity and long-term sequelae. The incidence and distribution…

View details →DOI: 10.12659/msm.949933
Negative / Null Result ReportOpen accessMedicine

Does attachment removal damage enamel? Influence of adhesive, resin, and bur on surface integrity.

Canadas MDB, Sousa ABS, Panzeri FC · 2026 · European journal of oral sciences

To evaluate the combination of composites, adhesive systems, and burs considering artificial accelerated aging (AAA), influence enamel roughness and morphology after attachment removal. One hundred ninety-two bovine enamel specimens were…

View details →DOI: 10.1111/eos.70088
Negative / Null Result ReportMedicine

Analysis of Contrast-enhanced CT Radiation Dose in Children.

Wang F, Sheng J, Zhang G et al. · 2026 · Health physics

Reducing radiation exposure in pediatric imaging is a key focus globally, and it is necessary to establish diagnostic reference levels (DRLs) for contrast-enhanced computed tomography (CT) in children. This study assesses typical radiation…

View details →DOI: 10.1097/hp.0000000000002147
Negative / Null Result ReportMedicine

AI-assisted radiomics for classification of benign and non-benign right heart masses in 2D-echocardiography.

Chen Y, Deng M, Xie L et al. · 2026 · Journal of translational medicine

Background The rarity of right heart masses challenges diagnostic proficiency, while reproducibility is affected by the echocardiography operator. Artificial intelligence (AI)-based imaging tools may help address these limitations. Methods…

View details →DOI: 10.1186/s12967-026-08322-8
Negative / Null Result ReportOpen accessMedicine

Safety of flexible bronchoscopy in elderly patients.

Spiegel S, Hübner RH, Schürmann D et al. · 2026 · BMC pulmonary medicine

Background Flexible bronchoscopy is an indispensable tool in respiratory medicine. In the context of an aging society and increasing life expectancy, the number of elderly, often multimorbid patients is growing. This raises important…

View details →DOI: 10.1186/s12890-026-04326-8
Negative / Null Result ReportMedicine

Impact of primary tumor SUVmax on PET accuracy in mediastinal lymph node staging of non-small cell lung cancer (NSCLC).

Kużdżał A, Gambuś K, Moszczyński K et al. · 2026 · Advances in clinical and experimental medicine : official organ Wroclaw Medical University

Background Positron emission tomography (PET) using 18-fluorodeoxyglucose (18-FDG) is the primary imaging modality for mediastinal staging of lung cancer. Higher standardized uptake value (SUVmax) reportedly correlates with more aggressive…

View details →DOI: 10.17219/acem/210368
Negative / Null Result ReportOpen accessMedicine

Comparing continuous bilateral quadratus lumborum block with continuous epidural block for analgesia and perioperative outcomes in colorectal cancer surgery: A noninferiority randomized controlled trial.

Roy S, Gupta N, Bharti SJ et al. · 2026 · Journal of anaesthesiology, clinical pharmacology

Background and aims Managing acute postsurgical pain following midline exploratory laparotomy in colorectal cancer patients involves various approaches, such as central neuraxial blockade, patient-controlled intravenous analgesia with…

View details →DOI: 10.4103/joacp.joacp_293_25
Negative / Null Result ReportMedicine

Prostate cancer detection by MRI-ultrasonography fusion transperineal vs transrectal biopsy: a randomised control trial.

Schieda N, Morash C, Lavallee LT et al. · 2025 · BJU international

Objective To compare clinically significant prostate cancer (CS-PCa) detection by transperineal (TP) compared to transrectal (TR) magnetic resonance imaging (MRI)-ultrasonography (US) fusion prostate biopsy. Patients and methods Males with…

View details →DOI: 10.1111/bju.16831
Negative / Null Result ReportMedicine

Pigmented Villonodular Synovitis: A Metastatic Melanoma Imitator.

Fields BC, Jain AJ, Prieto VG et al. · 2024 · The American Journal of dermatopathology

Abstract A 45-year-old woman with a history of previously treated left plantar foot melanoma presented with a left thigh mass. Fine needle aspiration findings were concerning for metastatic melanoma (MM). Imaging was remarkable for…

View details →DOI: 10.1097/dad.0000000000002771
Negative / Null Result ReportMedicine

Surgical nodal staging in rhabdomyosarcoma of the bladder and/or prostate with or without nodal or metastatic spread. A report from the European Paediatric Soft-Tissue Sarcoma Study Group (EpSSG).

Smeulders N, Gaze MN, Guérin F et al. · 2026 · Journal of pediatric surgery

Background Risk stratification of rhabdomyosarcoma (RMS) requires accurate staging, with histological nodal assessment being of critical importance for specific tumour sites. This report explores the value of surgical nodal staging in…

View details →DOI: 10.1016/j.jpedsurg.2026.163162
Negative / Null Result ReportMedicine

[Comparison of the modified Kadish, AJCC T and Dulguerov T staging systems for olfactory neuroblastoma: analysis of the SEER database].

Lyu HH, Wen X, Lin JT et al. · 2025 · Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery

Objective: To compare the Kadish T staging, AJCC T staging, and Dulguerov T staging system in terms of their impact on surgical treatment selection and survival prognosis in patients with olfactory neuroblastoma (ONB). Methods: The cases…

View details →DOI: 10.3760/cma.j.cn115330-20240723-00438
Negative / Null Result ReportOpen accessMedicine

Development of Machine Learning Models to Predict Daily Gas Ebullition Flux in Waterways from Sediment Characteristics.

Mansouri M, Rockne KJ · 2026 · ACS environmental Au

Gas ebullition plays a critical role in facilitating contaminant transport from the sediment to the water column. Predicting gas ebullition accurately is necessary for managing sediments and assessing sediment/water flux, and many…

View details →DOI: 10.1021/acsenvironau.5c00221
Negative / Null Result ReportMedicine

Comparison of post-stroke white matter assessment using disconnectome-symptom mapping versus quantitative diffusion MRI.

Domin M, Liew SL, Hordacre B et al. · 2025 · NeuroImage

Indirect structural disconnection-symptom mapping allows white matter impairment to be determined without the need for multi-directional diffusion (MDDW) imaging for each individual. Although widely used this method has not been validated.…

View details →DOI: 10.1016/j.neuroimage.2025.121347
Negative / Null Result ReportOpen accessMedicine

Surveillance after treatment for head and neck cancer.

Koivunen P · 2026 · Current opinion in otolaryngology & head and neck surgery

Purpose of review Systematic follow-up protocols, often including regular imaging, are an essential component of posttreatment care for head and neck cancer, aimed at the early detection of disease relapse and mitigating treatment-related…

View details →DOI: 10.1097/moo.0000000000001102
Negative / Null Result ReportOpen accessMedicine

Analysing the clinical outcomes between FIGO 2009 and 2023 staging for endometrial cancer-a single institution retrospective study.

Vuppu DP, Rajanbabu A, Nair IR et al. · 2025 · Ecancermedicalscience

The latest International Federation of Gynaecology and Obstetrics (FIGO) staging for endometrial cancer incorporated molecular profiles and histopathological factors into the basic staging framework. This study was done to determine its…

View details →DOI: 10.3332/ecancer.2025.1836
Negative / Null Result ReportMedicine

Tumor-induced rickets/osteomalacia (TIO): diagnostic pitfalls and therapeutic options.

Ito N, Fukumoto S · 2025 · Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research

A 10-year-old girl developed bilateral gonalgia and waddling gait. Biochemical and imaging studies showed hypophosphatemia with impaired proximal tubular phosphate reabsorption and high intact fibroblast growth factor 23 (FGF23) level,…

View details →DOI: 10.1093/jbmr/zjaf047