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Failure-mode index

Search what already failed

A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.

1896 results for "Mpro" · page 26 of 64

Negative / Null Result ReportOpen accessComputer Science

KNN-LM Does Not Improve Open-ended Text Generation

Shufan Wang, Yixiao Song, Andrew Drozdov et al. · 2023 · arXiv

In this paper, we study the generation quality of interpolation-based retrieval-augmented language models (LMs). These methods, best exemplified by the KNN-LM, interpolate the LM's predicted distribution of the next word with a distribution formed from the most relevant retrievals for a given prefix. While the KNN-LM and related methods yield impressive decreases in perplexity, we discover that they do not exhibit corresponding improvements in open-ended generation quality, as measured by both automatic evaluation metrics (e.g., MAUVE) and human evaluations. Digging deeper, we find that interp

Negative / Null Result Report

Modified string test to improve and confirm by molecular characterization for bacterial identification

Muhammad Dawood Mian, Saadullah Jan Khan, Rehana Rani et al. · 2026 · Access Microbiology

Rapid and reliable identification of bacteria is essential in clinical and environmental microbiology. Gram staining remains a widely used method for preliminary classification; however, it may require additional steps and can be difficult…

View details →DOI: 10.1099/acmi.0.000965.v3
Negative / Null Result Report

Abstract 17917: Is Small Change Significant? Association of Small Differences in Life's Simple 7 and Mortality: the Reasons for Geographic and Racial Differences in Stroke (REGARDS) Cohort

Mary Cushman, Suzanne E Judd, Virginia J Howard et al. · 2011 · Circulation

Background. The AHA 2020 Goal includes improving cardiovascular health, defined using a metric consisting of 7 health factors, Life's Simple 7. A central concept of the goal is that small improvements in behavior / lifestyle factors at the…

View details →DOI: 10.1161/circ.124.suppl_21.a17917
Negative / Null Result ReportOpen accessPublic aspects of medicine

Supporting antiretroviral therapy uptake and adherence: the SUPA research programme and RCT

Rob Horne, Caroline Sabin, Trudie Chalder et al. · 2025 · Programme Grants for Applied Research

Background Antiretroviral therapy has transformed human immunodeficiency virus infection intoa chronic condition associated with normal life expectancy. In the United Kingdom, the uptake of antiretroviral therapy is generally high, but a delay in starting antiretroviral therapy and non-adherence compromise the health and well-being of people living with human immunodeficiency virus, increase the risk of transmission of human immunodeficiency virus and increase National Health Service costs. Objectives The overall aim was to improve antiretroviral therapy uptake and adherence by addressing perc

View details →DOI: 10.3310/kppw8401
Negative / Null Result ReportOpen accessComputer Science

Haptic human-human interaction does not improve individual visuomotor adaptation

Niek Beckers, Edwin van Asseldonk, Herman van der Kooij · 2020 · arXiv

Haptic interaction between two humans, for example, a physiotherapist assisting a patient regaining the ability to grasp a cup, likely facilitates motor skill acquisition. Haptic human-human interaction has been shown to enhance individual performance improvement in a tracking task with a visuomotor rotation perturbation. These results are remarkable given that haptically assisting or guiding an individual rarely benefits their individual improvement when the assistance is removed. We, therefore, replicated a study that reported that haptic interaction between humans was beneficial for individ

Negative / Null Result ReportOpen accessMedicine

Optimization of technological parameters for durum wheat pasta production with carrot powder and ion-ozonated water

Galiya Iskakova, Bauyrzhan Iztayev, Auyelbek Iztayev et al. · 2025 · Scientific Reports

Abstract The quality of food products and a balanced diet play a key role in maintaining health and improving the quality of life. Due to the high popularity of pasta, a promising direction is the development of recipes that include whole grain flour, carrot powder and ion-ozonated water, which increase the nutritional value of the product and improve its chemical composition. The aim of this study was to optimise the technological modes of production of durum wheat pasta using carrot powder and ion-ozonated water to minimise the loss of dry matter (DM) during cooking and increase the protein

View details →DOI: 10.1038/s41598-025-28027-0
Negative / Null Result ReportOpen accessBusiness

The Success of Online Passport Queue Registration Applications Using Delone and Mclean Models

Ivan Ramos, Lilik Noor Yuliati, Megawati Simanjuntak · 2022 · Jurnal Aplikasi Bisnis dan Manajemen

Advancement in sophisticated information technology can be used for innovation in access to public services. In this study, the public service studied was the Online Passport Queue Registration Application (APAPO) at the Class I Non-TPI Bogor Immigration Office. This study aims to analyze the effect of system quality, information quality, service quality, user characteristics, usage rate, user satisfaction on net benefits APAPO using DeLone and McLean and find out the priority factors for improvement using the Important-Performance Analysis (IPA) method. The sampling technique used was conveni

View details →DOI: 10.17358/jabm.8.1.33
Negative / Null Result ReportOpen accessBusiness

Catur purusa artha: Antecedent and moderator for improving business performance

Dewa Nyoman Benni Kusyana, Putu Sri Hartati, Ida Ayu Widani Sugianingrat et al. · 2024 · Jurnal Ekonomi dan Bisnis

This research was conducted to determine the influence of organizational culture on business performance, mediated by innovation and moderated by catur purusa artha. The subjects of this research were the cooperative heads or managers of 503 cooperative units in Denpasar City. The Yamane formula was used to determine the sample size, which was determined to be 83 cooperative heads/managers using a proportionate random sampling technique. Data analysis was carried out using structural equation modelling – partial least squares (SEM-PLS). Data analysis using PLS was carried out with two measurem

View details →DOI: 10.24914/jeb.v27i2.10287
Negative / Null Result ReportOpen accessComputer Science

Understanding Why Generalized Reweighting Does Not Improve Over ERM

Runtian Zhai, Chen Dan, Zico Kolter et al. · 2022 · arXiv

Empirical risk minimization (ERM) is known in practice to be non-robust to distributional shift where the training and the test distributions are different. A suite of approaches, such as importance weighting, and variants of distributionally robust optimization (DRO), have been proposed to solve this problem. But a line of recent work has empirically shown that these approaches do not significantly improve over ERM in real applications with distribution shift. The goal of this work is to obtain a comprehensive theoretical understanding of this intriguing phenomenon. We first posit the class o

Negative / Null Result ReportOpen accessMedicine (General)

MULLIGAN VERSUS MAITLAND MOBILIZATION ON THORACIC KYPHOTIC ANGLE IN POSTURAL KYPHOSIS

Mohamed Ibrahim Fathallah Abdelhay, Mohamed Hussein Elgendy, Yasser Ramzy Lasheen · 2017 · International Journal of Physiotherapy

Background: Postural hypnosis can lead to cervical pain or bad cosmetic appearance.There is a lack in the literature supporting the efficacy of spinal mobilization techniques in restoring normal thoracic curvature.Mulligan and Maitland's mobilization were used to improve range of motion and referred pain not to restore normal kyphotic angle. The purpose: this study was conducted to compare the efficacy of Mulligan and Maitland spinal mobilization on a kyphotic angle in postural kyphosis. Subjects: seventy-five male subjects with postural kyphosis their age (17-21) years were included in the st

View details →DOI: 10.15621/ijphy/2017/v4i3/149069
Negative / Null Result Report

Dampak Sosial Ekonomi pada Keluaga Penerima Manfaat (KPM) Program Keluarga Harapan (PKH) Exit Mandiri di Kecamatan Pagelaran Kabuoaten Pringsewu dalam Perspektif The Most Significant Change Technique (MSCt)

Ainun Oktavia Sari, Rahayu Sulistyowati, Ita Prihantika · 2020 · Administrativa: Jurnal Birokrasi, Kebijakan dan Pelayanan Publik

The Conditional Cash Transfer (CCT) is a conditional social cash transfer program that provides assistance to Very Poor Households (RTSM) appointed as participants in the Conditional Cash Transfer program which is related to improving the…

View details →DOI: 10.23960/administrativa.v2i3.51
Negative / Null Result ReportOpen accessMathematics

Private Parking Space Sharing Intention in China: An Empirical Study Based on the MIMIC Model

Ange Wang, Hongzhi Guan, Yan Han et al. · 2021 · Discrete Dynamics in Nature and Society

The shared parking scheme improves the utilization rate of existing parking resources and contributes to the sustainable development of cities, but many private parking spaces that are not included in the shared parking scheme have a low utilization rate in China. In order to better promote the shared parking scheme, it is necessary to study the intention of the owners of private parking spaces to share their parking spaces. Therefore, this paper used the Unified Theory of Acceptance and Use of Technology (UTAUT) and Benefit-Risk Analysis Model (BRA) as the combined theoretical framework (C-UT

View details →DOI: 10.1155/2021/9283686
Negative / Null Result ReportOpen accessMathematics

Does preregistration improve the credibility of research findings?

Mark Rubin · 2020 · arXiv

Preregistration entails researchers registering their planned research hypotheses, methods, and analyses in a time-stamped document before they undertake their data collection and analyses. This document is then made available with the published research report to allow readers to identify discrepancies between what the researchers originally planned to do and what they actually ended up doing. This historical transparency is supposed to facilitate judgments about the credibility of the research findings. The present article provides a critical review of 17 of the reasons behind this argument.

Negative / Null Result ReportOpen accessPublic aspects of medicine

Effect of drug utilization reviews on the quality of in-hospital prescribing: a quasi-experimental study

Chabot Isabelle, Potvin Louise, Moisan Jocelyne et al. · 2006 · BMC Health Services Research

Abstract Background Drug utilization review (DUR) programs are being conducted in Canadian hospitals with the aim of improving the appropriateness of prescriptions. However, there is little evidence of their effectiveness. The objective of this study was to assess the impact of both a retrospective and a concurrent DUR programs on the quality of in-hospital prescribing. Methods We conducted an interrupted time series quasi-experimental study. Using explicit criteria for quality of prescribing, the natural history of cisapride prescription was established retrospectively in three university-aff

View details →DOI: 10.1186/1472-6963-6-33
Negative / Null Result ReportOpen accessAgriculture

Legume/Maize Intercropping and N Application for Improved Yield, Quality, Water and N Utilization for Forage Production

Haixing Zhang, Wei Shi, Shahzad Ali et al. · 2022 · Agronomy

Legume/maize intercropping has been practiced in many countries as a sustainable cropping system, but the effects of intercropping legumes with maize together with N application rates on biomass yield, quality, water-use efficiency (WUE), and nitrogen use efficiency (NUE) are limited under arid conditions in Northwest China. Field experiments were carried out in arid areas of Northwest China from 2019 to 2020 with three planting patterns (LM: Dolichos lablab ( Lablab purpureus L.)/silage maize ( Zea mays L.) intercropping; FM: Fodder soybean ( Glycine max L.)/silage maize intercropping; M: sil

View details →DOI: 10.3390/agronomy12081777
Negative / Null Result ReportOpen accessTherapeutics. Pharmacology

Impact of a DSS-supported medication review on the safety of drug therapy and quality of life in patients with antithrombotic therapy

Tanja Elnaz Hassanzadeh, Tanja Elnaz Hassanzadeh, Carina Hohmann et al. · 2024 · Frontiers in Pharmacology

Polypharmacy is common among patients with antithrombotic medication, giving rise to concerns about Drug-Related Problems (DRPs). Therefore, these patients would benefit from a Medication Review (MR) along with pharmacist counselling to reduce the risks accompanying polymedication. This prospective study presents a concept for MRs that are applicable in German community pharmacies and can efficiently support pharmacist counselling and improve the safety of drug therapy. As this is a major challenge in everyday pharmacy practice, we used a Decision Support System (DSS) to evaluate its ability t

View details →DOI: 10.3389/fphar.2024.1194201
Negative / Null Result ReportOpen accessComputer Science

Does Weighting Improve Matrix Factorization for Recommender Systems?

Alex Ayoub, Samuel Robertson, Dawen Liang et al. · 2025 · arXiv

Matrix factorization is a widely used approach for top-N recommendation and collaborative filtering. When implemented on implicit feedback data (such as clicks), a common heuristic is to upweight the observed interactions. This strategy has been shown to improve performance for certain algorithms. In this paper, we conduct a systematic study of various weighting schemes and matrix factorization algorithms. Somewhat surprisingly, we find that training with unweighted data can perform comparably to, and sometimes outperform, training with weighted data, especially for large models. This observat

Negative / Null Result ReportOpen accessMathematics

The Poincaré Inequality does not improve with blow-up

Andrea Schioppa · 2015 · arXiv

For each $β>1$ we construct a family $F_β$ of metric measure spaces which is closed under the operation of taking weak-tangents (i.e.~blow-ups), and such that each element of $F_β$ admits a $(1,P)$-Poincaré inequality if and only if $P>β$.

Negative / Null Result ReportOpen accessEconomics, Econometrics and Finance

Does Anxiety Improve Economic Decision-Making?

Ian Crawford, Carl-Emil Pless · 2026 · arXiv

We study the associations between everyday economic decision-making quality and people's emotional states. Using high-frequency, highly disaggregated consumer "scanner" data, we show that the cost of poor decision-making is substantial, on average equal to around half of day-to-day consumption budgets. While material circumstances help explain decision-making quality, how people feel about those circumstances is equally important. Contrary to evidence that stress and worry impair performance in settings where distraction is costly, we find these same feelings are associated with improved decis

Negative / Null Result ReportOpen accessMedicine

Assessment of the Physical Activity of Elderly Population of Isfahan, Iran

Sayed Reza Eshaghi, Armindokht Shahsanai, Maryam Mellat Ardakani · 2011 · مجله دانشکده پزشکی اصفهان

Background: Improvement of medical care and decreasing of mortality, have lead to an increase in ageing in Iranian population. The main goal of Active ageing is improving the quality of life. Physical activity is one of the factors that is important to achieve a good quality of life. The aim of this study was to evaluate the physical activity of the elderly in Isfahan. Methods: This cross sectional study was carried out on 350 old residents of Isfahan, Iran between the years 2009-2010. Multi stage cluster sampling technique was used to collect the sample population. Rapid assessment of physica

Abandoned Hypothesis

How can I find my own voice through my instrument

Julia Casañas Cast · 2020 · Royal Conservatoire Research Portal

Many classical musicians can suffer from tension and nervousness during solo performance. This research looks at how practicing improvisation and creative body movement, as well as creating one’s own performance together with a dancer, can…

View details →DOI: 10.22501/koncon.792184
Negative / Null Result ReportOpen accessComputer Science

When is dataset cartography ineffective? Using training dynamics does not improve robustness against Adversarial SQuAD

Paul K. Mandal · 2025 · arXiv

In this paper, I investigate the effectiveness of dataset cartography for extractive question answering on the SQuAD dataset. I begin by analyzing annotation artifacts in SQuAD and evaluate the impact of two adversarial datasets, AddSent and AddOneSent, on an ELECTRA-small model. Using training dynamics, I partition SQuAD into easy-to-learn, ambiguous, and hard-to-learn subsets. I then compare the performance of models trained on these subsets to those trained on randomly selected samples of equal size. Results show that training on cartography-based subsets does not improve generalization to

Negative / Null Result ReportOpen accessEconomic growth, development, planning

Effect of Macroeconomic Factors on The Small-Medium Enterprises Loans

Adhisty Mohammad Khariza, Arintoko Arintoko, Suprapto Suprapto · 2020 · Eko-Regional

Small-medium enterprises (SMEs) are the main pillar of the Indonesian economy. Based on 2016’s Economic Census, most businesses in Indonesia are SMEs, while SMEs absorb the majority of the workforce. The empowerment of SMEs is one way to improve the economy. To empower the SMEs sector, the Indonesian government launched the Kredit Usaha Rakyat (KUR) since 2007. The lasts policy is the provision of the mild interest rate for KUR since 2016. The hope is that with a mild interest rate, SMEs can get affordable financing access so they can be the driving force of the economy. However, credit demand

View details →DOI: 10.20884/1.erjpe.2020.15.2.1582
Negative / Null Result ReportOpen accessMathematics

Preregistration does not improve the transparent evaluation of severity in Popper's philosophy of science or when deviations are allowed

Mark Rubin · 2024 · arXiv

One justification for preregistering research hypotheses, methods, and analyses is that it improves the transparent evaluation of the severity of hypothesis tests. In this article, I consider two cases in which preregistration does not improve this evaluation. First, I argue that, although preregistration may facilitate the transparent evaluation of severity in Mayo's error statistical philosophy of science, it does not facilitate this evaluation in Popper's theory-centric approach. To illustrate, I show that associated concerns about Type I error rate inflation are only relevant in the error

Negative / Null Result ReportOpen accessBusiness

Pengaruh Kualitas Layanan, Ketersediaan Produk Wisata, Citra Destinasi Terhadap Kepuasan dan Loyalitas Destinasi Kampung Karuhun Sumedang

Rina Trisnawati, Nono Wibisono · 2022 · Jurnal Bisnis dan Kewirausahaan

Sumedang Regency is an area that has various types of tourist attractions but tourist visits to Sumedang fluctuate every year. One of the attractions in Sumedang is Kampung Karuhun which still needs improvement in several aspects. This study aims to identify the influence of the relationship of service quality, tourism product availability, destination image, consumer satisfaction and destination loyalty in Kampung Karuhun Sumedang. The research method used is a quantitative approach using a survey tool in the form of a questionnaire. This study collected data as many as 355 respondents. The a

View details →DOI: 10.31940/jbk.v18i3.238-247
Negative / Null Result ReportOpen accessComputer Science

Does Interaction Improve Bayesian Reasoning with Visualization?

Ab Mosca, Alvitta Ottley, Remco Chang · 2021 · arXiv

Interaction enables users to navigate large amounts of data effectively, supports cognitive processing, and increases data representation methods. However, there have been few attempts to empirically demonstrate whether adding interaction to a static visualization improves its function beyond popular beliefs. In this paper, we address this gap. We use a classic Bayesian reasoning task as a testbed for evaluating whether allowing users to interact with a static visualization can improve their reasoning. Through two crowdsourced studies, we show that adding interaction to a static Bayesian reaso

Negative / Null Result ReportOpen accessMedicine

Effect of Motor Cortex Transcranial Direct Current Stimulation (tDCS)on the Strength and Endurance performance of Healthy Collegiate Subjects

Sirous Nazari pirdoosti, Vahid Valipour dehnou, Ehsan Gharamanlou · 2019 · Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Īlām

Introduction: Transcranial direct current stimulation (tDCS) is a non-invasive technique used to modify the activity of the cortex of the brain. This form of current is capable of inducing changes in the electrical activity inside and outside of the neurons, which leads to a change in the resting membrane potential and thus improves the efficiency of the neural synapse. Therefore, the aim of this study was to investigate the effect of tDCS over motor cortex on strength and endurance performance of healthy collegiate subjects. Materials & Methods: In total, 10 young and healthy male subjects (a

Negative / Null Result ReportOpen accessComputer Science

Batch normalization does not improve initialization

Joris Dannemann, Gero Junike · 2025 · arXiv

Batch normalization is one of the most important regularization techniques for neural networks, significantly improving training by centering the layers of the neural network. There have been several attempts to provide a theoretical justification for batch ormalization. Santurkar and Tsipras (2018) [How does batch normalization help optimization? Advances in neural information rocessing systems, 31] claim that batch normalization improves initialization. We provide a counterexample showing that this claim s not true, i.e., batch normalization does not improve initialization.

Negative / Null Result ReportOpen accessComputer Science

Neural document expansion for ad-hoc information retrieval

Cheng Tang, Andrew Arnold · 2020 · arXiv

Recently, Nogueira et al. [2019] proposed a new approach to document expansion based on a neural Seq2Seq model, showing significant improvement on short text retrieval task. However, this approach needs a large amount of in-domain training data. In this paper, we show that this neural document expansion approach can be effectively adapted to standard IR tasks, where labels are scarce and many long documents are present.