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Failure-mode index

Search what already failed

A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.

46 results for "reproducibility" · page 2 of 2

Negative / Null Result ReportOpen accessMedicine

A single site, multi-operator precision study for second-generation HR-pQCT.

Stapleton JR, Heilmann NZ, Cattell K et al. · 2026 · JBMR plus

As HR-pQCT increases in popularity for studying bone dynamics, it becomes increasingly important to quantify the factors that impact rigor and reproducibility in research, particularly for longitudinal studies. Previously reported data for…

View details →DOI: 10.1093/jbmrpl/ziag097
Negative / Null Result ReportMedicine

AI-assisted radiomics for classification of benign and non-benign right heart masses in 2D-echocardiography.

Chen Y, Deng M, Xie L et al. · 2026 · Journal of translational medicine

Background The rarity of right heart masses challenges diagnostic proficiency, while reproducibility is affected by the echocardiography operator. Artificial intelligence (AI)-based imaging tools may help address these limitations. Methods…

View details →DOI: 10.1186/s12967-026-08322-8
Negative / Null Result ReportMedicine

[Comparison between methods to estimate total body fat mass in triathletes: dual X-ray absorptiometry, bioelectrical impedance and anthropometric equations].

Herrera-Torres OA, Flores-Zapata J, Ferreyro-Bravo F · 2026 · Nutricion hospitalaria

Introduction Introduction: the estimation of body fat mass (FM) can be performed using different methods. Although Dual-Energy X-ray Absorptiometry (DXA) is considered the reference technique due to its precision and reproducibility, its…

View details →DOI: 10.20960/nh.06323
Negative / Null Result ReportMedicine

A 25-year longitudinal study on dipping/nondipping tracking in the general population: the PAMELA study.

Cuspidi C, Facchetti R, Tadic M et al. · 2026 · Journal of hypertension

Background The long-term reproducibility of the nighttime blood pressure (BP) phenotypes, namely, dipping (D) and nondipping (ND) has never been described in population-based studies. We investigated this issue in the participants to the…

View details →DOI: 10.1097/hjh.0000000000004276
Negative / Null Result ReportOpen accessMedicine

The Reproducibility Movement in Psychology: Does Researcher Gender Affect How People Perceive Scientists With a Failed Replication?

Ashburn-Nardo L, Moss-Racusin CA, Smith JL et al. · 2022 · Frontiers in psychology

The reproducibility movement in psychology has resulted in numerous highly publicized instances of replication failures. The goal of the present work was to investigate people's reactions to a psychology replication failure vs. success,…

View details →DOI: 10.3389/fpsyg.2022.823147
Negative / Null Result ReportOpen accessMedicine

Reevaluating the senolytic activity of a GLS1 inhibitor and an anti-PD-1 antibody: toward greater reproducibility and methodological rigor.

Kawamoto S, Horiguchi H, Torigoe D et al. · 2026 · EMBO reports

The discovery of the senescence-associated secretory phenotype (SASP) has reshaped our understanding of cellular senescence, shifting its role from a solely tumor-suppressive mechanism to a potential driver of chronic inflammation and…

View details →DOI: 10.1038/s44319-026-00740-5
Negative / Null Result ReportOpen accessMedicine

Safety Audit of a Large Language Model for Lay Self-Triage Using Japanese Symptom Vignettes: Persistent Red-Flag Under-Triage Despite Improved Reproducibility Under Near-Deterministic Decoding.

Harada Y · 2026 · Cureus

Introduction Large language models are increasingly discussed as tools for patient-facing symptom assessment, but safe self-triage depends on the concrete next action recommended to the user rather than on generic urgency language alone.…

View details →DOI: 10.7759/cureus.105878
Negative / Null Result ReportMedicine

The Influence of Depth of Anesthesia on Motor Evoked Potentials Monitoring During Spinal Surgery in Youth: A Single-Center Prospective Study (SCOL Study).

Hudec J, Prokopova T, Hulkova M et al. · 2026 · Anesthesia and analgesia

Background Anesthetic agents or some pathophysiological conditions can affect transcranial motor evoked potentials (TcMEP) monitoring. However, the influence of depth of anesthesia on TcMEP reproducibility in youth remains unclear due to…

View details →DOI: 10.1213/ane.0000000000008158
Negative / Null Result ReportMedicine

Open- source computed tomography (CT)-based sarcopenia assessment in women with suspicious adnexal masses: a feasibility and reproducibility study.

Badran PM, Stecca CM, de Souza de Castro JT et al. · 2025 · Clinical radiology

Aim Ovarian cancer is the most lethal gynecologic malignancy, with prognosis linked to stage at diagnosis. Ultrasonography is the first-line tool for adnexal mass evaluation, while computed tomography (CT) supports staging and surgical…

View details →DOI: 10.1016/j.crad.2025.107088
Negative / Null Result ReportOpen accessMedicine

Investigating the replicability of preclinical cancer biology.

Errington TM, Mathur M, Soderberg CK et al. · 2021 · eLife

Replicability is an important feature of scientific research, but aspects of contemporary research culture, such as an emphasis on novelty, can make replicability seem less important than it should be. The Reproducibility Project: Cancer…

View details →DOI: 10.7554/elife.71601
Methods Dead-EndMedicine

Reproducibility of a Shear Wave Elastography Procedure for Assessing the Piriformis Muscle Stiffness in a Sample of Healthy Young Adults Under Controlled Laboratory Conditions: An Intra- and Inter-Examiner Reliability Study.

Varol U, Kobylarz MD, López-Redondo M et al. · 2026 · Journal of clinical medicine

Background/Objectives : Shear wave elastography (SWE) may provide an objective method for quantifying piriformis muscle stiffness, but its clinical and research use requires evidence that the measurement procedure is reliable. This study…

View details →DOI: 10.3390/jcm15124548
Negative / Null Result ReportOpen accessMedicine

Test-retest reliability and validity of the Importance of Olfaction Questionnaire in Denmark.

Daniel Tchemerinsky Konieczny, Alexander Wieck Fjaeldstad, Kristian Sandberg · 2024 · PLoS ONE

While measures to detect psychophysical olfactory ability are a crucial part of clinicians' assessment of potential olfactory loss, it gives no indication of how olfaction is experienced by the patient and these different aspects often deviate substantially. To ensure quality and reproducibility of subjectively reported olfactory experience and significance, the Importance of Olfaction Questionnaire (IO-Q) was introduced around a decade ago, and while initial validations have produced promising results, important aspects remain nearly unexamined. For example, the test-retest reliability has ra

View details →DOI: 10.1371/journal.pone.0269211
Negative / Null Result ReportMedicine

Repeatability and comparability of a new swept-source optical coherence tomographer in optical biometry.

C. E. Monera Lucas, J. Escolano Serrano, C. T. Tarazona Jaimes et al. · 2022 · Archivos de la Sociedad Española de Oftalmología

PURPOSE To evaluate the reproducibility in the measurement of ocular biometric parameters using a new swept-source optical coherence tomographer and its comparability with an optical low coherence reflectometry biometer. DESIGN An…

View details →DOI: 10.1016/j.oftale.2022.04.003