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Failure-mode index

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A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.

1757 results in Negative / Null Result Report for "Mpro" · page 19 of 59

Negative / Null Result ReportOpen accessComputer Science

Non-unitary neutrino mixing in the NO$ν$A near detector data

Ushak Rahaman, Soebur Razzaque · 2021 · arXiv

The $ν_μ\to ν_e$ oscillation probability over short baseline ($\lesssim 1$~km) would be negligible in case the mixing matrix for three active neutrinos is unitary. However, in case of non-unitary mixing of three neutrinos, this probability would be non-negligible due to the so-called "zero distance" effect. Hence, the near detector of the accelerator experiments such as NO$ν$A can provide strong constraints on the parameters of the non-unitary mixing with very large statistics. By analyzing the NO$ν$A near detector data we find that the non-unitary mixing does not improve fits to the $ν_e$ or

Negative / Null Result ReportOpen accessComputer Science

Background Knowledge Grounding for Readable, Relevant, and Factual Biomedical Lay Summaries

Domenic Rosati · 2023 · arXiv

Communication of scientific findings to the public is important for keeping non-experts informed of developments such as life-saving medical treatments. However, generating readable lay summaries from scientific documents is challenging, and currently, these summaries suffer from critical factual errors. One popular intervention for improving factuality is using additional external knowledge to provide factual grounding. However, it is unclear how these grounding sources should be retrieved, selected, or integrated, and how supplementary grounding documents might affect the readability or rele

Negative / Null Result ReportOpen accessComputer Science

Towards Deep Robot Learning with Optimizer applicable to Non-stationary Problems

Taisuke Kobayashi · 2020 · arXiv

This paper proposes a new optimizer for deep learning, named d-AmsGrad. In the real-world data, noise and outliers cannot be excluded from dataset to be used for learning robot skills. This problem is especially striking for robots that learn by collecting data in real time, which cannot be sorted manually. Several noise-robust optimizers have therefore been developed to resolve this problem, and one of them, named AmsGrad, which is a variant of Adam optimizer, has a proof of its convergence. However, in practice, it does not improve learning performance in robotics scenarios. This reason is h

Negative / Null Result ReportOpen accessComputer Science

DVB-S2 Spectrum Efficiency Improvement with Hierarchical Modulation

Hugo Meric, Jose Miguel Piquer · 2013 · arXiv

We study the design of a DVB-S2 system in order to maximise spectrum efficiency. This task is usually challenging due to channel variability. Modern satellite communications systems such as DVB-SH and DVB-S2 rely mainly on a time sharing strategy to optimise the spectrum efficiency. Recently, we showed that combining time sharing with hierarchical modulation can provide significant gains (in terms of spectrum efficiency) compared to the best time sharing strategy. However, our previous design does not improve the DVB-S2 performance when all the receivers experience low or large signal-to-noise

Negative / Null Result ReportOpen accessComputer Science

Long-Tail Crisis in Nearest Neighbor Language Models

Yuto Nishida, Makoto Morishita, Hiroyuki Deguchi et al. · 2025 · arXiv

The $k$-nearest-neighbor language model ($k$NN-LM), one of the retrieval-augmented language models, improves the perplexity for given text by directly accessing a large datastore built from any text data during inference. A widely held hypothesis for the success of $k$NN-LM is that its explicit memory, i.e., the datastore, enhances predictions for long-tail phenomena. However, prior works have primarily shown its ability to retrieve long-tail contexts, leaving the model's performance remain underexplored in estimating the probabilities of long-tail target tokens during inference. In this paper

Negative / Null Result ReportOpen accessComputer Science

Maximizing Prefix-Confidence at Test-Time Efficiently Improves Mathematical Reasoning

Matthias Otth, Jonas Hübotter, Ido Hakimi et al. · 2025 · arXiv

Recent work has shown that language models can self-improve by maximizing their own confidence in their predictions, without relying on external verifiers or reward signals. In this work, we study the test-time scaling of language models for mathematical reasoning tasks, where the model's own confidence is used to select the most promising attempts. Surprisingly, we find that we can achieve significant performance gains by continuing only the most promising attempt, selected by the model's prefix-confidence. We systematically evaluate prefix-confidence scaling on five mathematical reasoning da

Negative / Null Result ReportOpen accessPhysics

Is Externally Corrected Coupled Cluster Always Better than the Underlying Truncated Configuration Interaction?

Ilias Magoulas, Karthik Gururangan, Piotr Piecuch et al. · 2021 · arXiv

The short answer to the question in the title is 'no'. We identify classes of truncated configuration interaction (CI) wave functions for which the externally corrected coupled-cluster (ec-CC) approach using the three-body ($T_{3}$) and four-body ($T_{4}$) components of the cluster operator extracted from CI does not improve the results of the underlying CI calculations. Implications of our analysis, illustrated by numerical examples, for the ec-CC computations using truncated and selected CI methods are discussed. We also introduce a novel ec-CC approach using the $T_{3}$ and $T_{4}$ amplitud

Negative / Null Result Report

Administering tolfenamic acid to gilts and sows before artificial insemination did not improve litter size but tended to reduce post-service serum prostaglandin F2α levels

Pachara Pearodwong, Nithitad Jiebna, Padet Tummaruk · 2024 · The Thai Journal of Veterinary Medicine

This study examined the impact of intramuscular administration of tolfenamic acid 10 min before artificial insemination (AI) on serum PGF2α levels and reproductive performance in gilts and sows. In Experiment I, 20 gilts were divided into…

View details →DOI: 10.56808/2985-1130.3755
Negative / Null Result Report

Statistically significant improvement in hemophilia A control: a retrospective analysis of the effectiveness and safety of emicizumab in children with severe and inhibitor forms of hemophilia A

V. Yu. Petrov, I. N. Lavrentyeva, V. V. Vdovin et al. · 2024 · Pediatric Hematology/Oncology and Immunopathology

Hemophilia A presents a serious problem, especially in its severe and inhibitor forms, leading to severe bleeding and complications. The importance of studying the effectiveness and safety of new treatment approaches, particularly…

View details →DOI: 10.24287/1726-1708-2024-23-1-99-107
Negative / Null Result ReportOpen accessPhysics

The thermodynamics of prediction

Susanne Still, David A. Sivak, Anthony J. Bell et al. · 2012 · arXiv

A system responding to a stochastic driving signal can be interpreted as computing, by means of its dynamics, an implicit model of the environmental variables. The system's state retains information about past environmental fluctuations, and a fraction of this information is predictive of future ones. The remaining nonpredictive information reflects model complexity that does not improve predictive power, and thus represents the ineffectiveness of the model. We expose the fundamental equivalence between this model inefficiency and thermodynamic inefficiency, measured by dissipation. Our result

Negative / Null Result ReportOpen accessAgricultural and Biological Sciences

Inhibitory normalization of error signals improves learning in neural circuits

Roy Henha Eyono, Daniel Levenstein, Arna Ghosh et al. · 2026 · arXiv

Normalization is a critical operation in neural circuits. In the brain, there is evidence that normalization is implemented via inhibitory interneurons and allows neural populations to adjust to changes in the distribution of their inputs. In artificial neural networks (ANNs), normalization is used to improve learning in tasks that involve complex input distributions. However, it is unclear whether inhibition-mediated normalization in biological neural circuits also improves learning. Here, we explore this possibility using ANNs with separate excitatory and inhibitory populations trained on an

Negative / Null Result ReportOpen accessEngineering

Momentum-Net for Low-Dose CT Image Reconstruction

Siqi Ye, Yong Long, Il Yong Chun · 2020 · arXiv

This paper applies the recent fast iterative neural network framework, Momentum-Net, using appropriate models to low-dose X-ray computed tomography (LDCT) image reconstruction. At each layer of the proposed Momentum-Net, the model-based image reconstruction module solves the majorized penalized weighted least-square problem, and the image refining module uses a four-layer convolutional neural network (CNN). Experimental results with the NIH AAPM-Mayo Clinic Low Dose CT Grand Challenge dataset show that the proposed Momentum-Net architecture significantly improves image reconstruction accuracy,

Negative / Null Result ReportOpen accessComputer Science

Preventing Over-Smoothing for Hypergraph Neural Networks

Guanzi Chen, Jiying Zhang, Xi Xiao et al. · 2022 · arXiv

In recent years, hypergraph learning has attracted great attention due to its capacity in representing complex and high-order relationships. However, current neural network approaches designed for hypergraphs are mostly shallow, thus limiting their ability to extract information from high-order neighbors. In this paper, we show both theoretically and empirically, that the performance of hypergraph neural networks does not improve as the number of layers increases, which is known as the over-smoothing problem. To avoid this issue, we develop a new deep hypergraph convolutional network called De

Negative / Null Result ReportOpen accessComputer Science

Are Pre-trained Language Models Useful for Model Ensemble in Chinese Grammatical Error Correction?

Chenming Tang, Xiuyu Wu, Yunfang Wu · 2023 · arXiv

Model ensemble has been in widespread use for Grammatical Error Correction (GEC), boosting model performance. We hypothesize that model ensemble based on the perplexity (PPL) computed by pre-trained language models (PLMs) should benefit the GEC system. To this end, we explore several ensemble strategies based on strong PLMs with four sophisticated single models. However, the performance does not improve but even gets worse after the PLM-based ensemble. This surprising result sets us doing a detailed analysis on the data and coming up with some insights on GEC. The human references of correct s

Negative / Null Result ReportOpen accessComputer Science

Utility-efficient Differentially Private K-means Clustering based on Cluster Merging

Tianjiao Ni, Minghao Qiao, Zhili Chen et al. · 2020 · arXiv

Differential privacy is widely used in data analysis. State-of-the-art $k$-means clustering algorithms with differential privacy typically add an equal amount of noise to centroids for each iterative computation. In this paper, we propose a novel differentially private $k$-means clustering algorithm, DP-KCCM, that significantly improves the utility of clustering by adding adaptive noise and merging clusters. Specifically, to obtain $k$ clusters with differential privacy, the algorithm first generates $n \times k$ initial centroids, adds adaptive noise for each iteration to get $n \times k$ clu

Negative / Null Result ReportOpen accessComputer Science

Does Character-level Information Always Improve DRS-based Semantic Parsing?

Tomoya Kurosawa, Hitomi Yanaka · 2023 · arXiv

Even in the era of massive language models, it has been suggested that character-level representations improve the performance of neural models. The state-of-the-art neural semantic parser for Discourse Representation Structures uses character-level representations, improving performance in the four languages (i.e., English, German, Dutch, and Italian) in the Parallel Meaning Bank dataset. However, how and why character-level information improves the parser's performance remains unclear. This study provides an in-depth analysis of performance changes by order of character sequences. In the exp

Negative / Null Result ReportOpen accessComputer Science

New physics in $B \to ππ$ and $B \to πK$ decays

Seungwon Baek · 2006 · arXiv

We perform a combined analysis of $B \to ππ$ and $B \to πK$ decays with the current experimental data. Assuming SU(3) flavor symmetry and no new physics contributions to the topological amplitudes, we demonstrate that the conventional parametrization in the Standard Model (SM) does not describe the data very well, in contrast with a similar analysis based on the earlier data. It is also shown that the introduction of smaller amplitudes and reasonable SU(3) breaking parameters does not improve the fits much. Interpreting these puzzling behaviors in the SM as a new physics (NP) signal, we study

Negative / Null Result ReportOpen accessMathematics

Stein's method and locally dependent point process approximation

Aihua Xia, Fuxi Zhang · 2011 · arXiv

Random events in space and time often exhibit a locally dependent structure. When the events are very rare and dependent structure is not too complicated, various studies in the literature have shown that Poisson and compound Poisson processes can provide adequate approximations. However, the accuracy of approximations does not improve or may even deteriorate when the mean number of events increases. In this paper, we investigate an alternative family of approximating point processes and establish Stein's method for their approximations. We prove two theorems to accommodate respectively the po

Negative / Null Result ReportOpen accessComputer Science

Phase Estimation of Coherent States with a Noiseless Linear Amplifier

Syed Assad, Mark Bradshaw, Ping Koy Lam · 2016 · arXiv

Amplification of quantum states is inevitably accompanied with the introduction of noise at the output. For protocols that are probabilistic with heralded success, noiseless linear amplification in theory may still possible. When the protocol is successful, it can lead to an output that is a noiselessly amplified copy of the input. When the protocol is unsuccessful, the output state is degraded and is usually discarded. Probabilistic protocols may improve the performance of some quantum information protocols, but not for metrology if the whole statistics is taken into consideration. We calcula

Negative / Null Result ReportOpen accessMathematics

An alternative approach to Shnirelman's inequality

Martina Zizza · 2024 · arXiv

In this paper we examine the discrete Shnirelman's inequality [Shnirelman A., 1985], which relates the $L^2$-distance of two discrete configurations of a fluid to the $L^1_tL^2_x$-norm of the vector field connecting them. Our proof is inspired by [Shnirelman A., 1985], where it was obtained $α=\frac{1}{64}$ in dimension $ν=2$, while here we get $α\geq\frac{2}{7}$. Moreover we prove that $α\geq\frac{1}{ν+1}$ for any dimension $ν\geq 3$. We point out that, even if this does not improve the bound in the continuous version, where it was proved that $α\geq\frac{2}{4+ν}$, with $ν\geq 3$, our bound i

Negative / Null Result ReportOpen accessComputer Science

Comparative Analysis and Parametric Tuning of PPO, GRPO, and DAPO for LLM Reasoning Enhancement

Yongsheng Lian · 2025 · arXiv

This study presents a systematic comparison of three Reinforcement Learning (RL) algorithms (PPO, GRPO, and DAPO) for improving complex reasoning in large language models (LLMs). Our main contribution is a controlled transfer-learning evaluation: models are first fine-tuned on the specialized Countdown Game and then assessed on a suite of general-purpose reasoning benchmarks. Across all tasks, RL-trained models outperform their corresponding base models, although the degree of improvement differs by benchmark. Our parametric analysis offers practical guidance for RL-based LLM training. Increas

Negative / Null Result ReportOpen accessMathematics

Column generation for the discrete Unit Commitment problem with min-stop ramping constraints

Nicolas Dupin · 2019 · arXiv

The discrete unit commitment problem with min-stop ramping constraints optimizes the daily production of thermal power plants (coal, gas, fuel units). For this problem, compact Integer Linear Programming (ILP) formulations have been designed to solve exactly small instances and heuristically real-size instances. This paper investigates whether Dantzig-Wolfe reformulation allows to improve the previous exact method and matheuristics. The extended ILP formulation is presented with the column generation algorithm to solve its linear relaxation. The experimental results show that the Dantzig-Wolfe

Negative / Null Result ReportOpen accessComputer Science

Topological based classification using graph convolutional networks

Roy Abel, Idan Benami, Yoram Louzoun · 2019 · arXiv

In colored graphs, node classes are often associated with either their neighbors class or with information not incorporated in the graph associated with each node. We here propose that node classes are also associated with topological features of the nodes. We use this association to improve Graph machine learning in general and specifically, Graph Convolutional Networks (GCN). First, we show that even in the absence of any external information on nodes, a good accuracy can be obtained on the prediction of the node class using either topological features, or using the neighbors class as an inp

Negative / Null Result ReportOpen accessComputer Science

IUTEAM1 at MEDIQA-Chat 2023: Is simple fine tuning effective for multilayer summarization of clinical conversations?

Dhananjay Srivastava · 2023 · arXiv

Clinical conversation summarization has become an important application of Natural language Processing. In this work, we intend to analyze summarization model ensembling approaches, that can be utilized to improve the overall accuracy of the generated medical report called chart note. The work starts with a single summarization model creating the baseline. Then leads to an ensemble of summarization models trained on a separate section of the chart note. This leads to the final approach of passing the generated results to another summarization model in a multi-layer/stage fashion for better coh

Negative / Null Result ReportOpen accessComputer Science

Improving Low Compute Language Modeling with In-Domain Embedding Initialisation

Charles Welch, Rada Mihalcea, Jonathan K. Kummerfeld · 2020 · arXiv

Many NLP applications, such as biomedical data and technical support, have 10-100 million tokens of in-domain data and limited computational resources for learning from it. How should we train a language model in this scenario? Most language modeling research considers either a small dataset with a closed vocabulary (like the standard 1 million token Penn Treebank), or the whole web with byte-pair encoding. We show that for our target setting in English, initialising and freezing input embeddings using in-domain data can improve language model performance by providing a useful representation o

Negative / Null Result ReportOpen accessComputer Science

A Note on Over-Smoothing for Graph Neural Networks

Chen Cai, Yusu Wang · 2020 · arXiv

Graph Neural Networks (GNNs) have achieved a lot of success on graph-structured data. However, it is observed that the performance of graph neural networks does not improve as the number of layers increases. This effect, known as over-smoothing, has been analyzed mostly in linear cases. In this paper, we build upon previous results \cite{oono2019graph} to further analyze the over-smoothing effect in the general graph neural network architecture. We show when the weight matrix satisfies the conditions determined by the spectrum of augmented normalized Laplacian, the Dirichlet energy of embeddin

Negative / Null Result ReportOpen accessComputer Science

Appearance and disappearance signals at a beta-Beam and a Super-Beam facility

A. Donini, E. Fernandez-Martinez, S. Rigolin · 2004 · arXiv

In this letter we present the study of the eightfold degeneracy in the $(θ_{13},δ)$ measurement including both appearance and disappearance channels. We analyse, for definiteness, the case of a standard low-$γ$ $β$-Beam and a 4 MWatt SPL Super-Beam facility, both aiming at a UNO-like Mton water Cerenkov detector located at the Frejus laboratory, $L = 130$ km. In the $β$-Beam case, the \nue disappearance channel does not improve the $(θ_{13},δ)$ measurement when a realistic (i.e. $\ge$ 2%) systematic error is included. In the Super-Beam case, the \numu disappearance channel could, instead, be q

Negative / Null Result ReportOpen accessComputer Science

New Physics effect on $B_c \to J/ψτ\barν$ in relation to the $R_{D^{(*)}}$ anomaly

Ryoutaro Watanabe · 2017 · arXiv

We study possible new physics (NP) effects on $B_c \to J/ψτ\barν$, which has been recently measured at LHCb as the ratio of $R_{J/ψ} = \mathcal B(B_c \to J/ψτ\barν)/\mathcal B(B_c \to J/ψμ\barν)$. Combining it with the long-standing $R_{D^{(*)}}$ measurements, in which the discrepancy with the prediction of the standard model is present, we find possible solutions to the anomaly by several NP types. Then, we see that adding the $R_{J/ψ}$ measurement does not improve NP fit to data, but the NP scenarios still give better $χ^2$ than the SM. We also investigate indirect NP constraints from the li

Negative / Null Result ReportOpen accessPhysics

Entanglement production by independent quantum channels

Örs Legeza, Florian Gebhard, Jörg Rissler · 2005 · arXiv

For the one-dimensional Hubbard model subject to periodic boundary conditions we construct a unitary transformation between basis states so that open boundary conditions apply for the transformed Hamiltonian. Despite the fact that the one-particle and two-particle interaction matrices link nearest and next-nearest neighbors only, the performance of the density-matrix renormalization group method for the transformed Hamiltonian does not improve. Some of the new interactions act as independent quantum channels which generate the same level of entanglement as periodic boundary conditions in the o

Negative / Null Result ReportOpen accessMathematics

The Second Picard iteration of NLS on the $2d$ sphere does not regularize Gaussian random initial data

Nicolas Burq, Nicolas Camps, Mickaël Latocca et al. · 2024 · arXiv

We consider the Wick ordered cubic Schrödinger equation (NLS) posed on the two-dimensional sphere, with initial data distributed according to a Gaussian measure. We show that the second Picard iteration does not improve the regularity of the initial data in the scale of the classical Sobolev spaces. This is in sharp contrast with the Wick ordered NLS on the two-dimensional tori, a model for which we know from the work of Bourgain that the second Picard iteration gains one half derivative. Our proof relies on identifying a singular part of the nonlinearity. We show that this singular part is re