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Failure-mode index

Search what already failed

A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.

1894 results for "Mpro" · page 16 of 64

Negative / Null Result Report

A single session of a beach volleyball exergame did not improve state anxiety level in healthy adult women

Vinnycius Nunes de Oliveira, Ricardo Borges Viana, João Victor Rosa de Freitas et al. · 2024 · BMC Sports Science, Medicine and Rehabilitation

Abstract This study evaluated the acute effect of the exergame Kinect Sports ® beach volleyball on state anxiety level in adult women. Thirty healthy adult women (age: 21 [4] years, body mass: 54.70 [19.50] kg, height: 1.61 ± 0.05 m, and…

View details →DOI: 10.1186/s13102-024-00859-9Cited by 2
Negative / Null Result Report

How did New Zealand’s regional District Health Board groupings work to improve service integration and health outcomes: a realist evaluation

Erin Penno, Carol Atmore, Brett Maclennan et al. · 2023 · BMJ Open

Objectives In Aotearoa New Zealand (NZ), integration across the healthcare continuum has been a key approach to strengthening the health system and improving health outcomes. A key example has been four regional District Health Board (DHB)…

View details →DOI: 10.1136/bmjopen-2023-079268Cited by 2
Negative / Null Result Report

Did the Inclusion of China’s A‐Shares in the MSCI Index Improve the Information Content of Listed Firms? Analysis Based on Stock Price Synchronisation and Environmental Social Governance

Jing Wu · 2022 · Wireless Communications and Mobile Computing

Chinese A‐shares were officially included in the Morgan Stanley Capital International (MSCI) Emerging Markets Index from June 2018. The inclusion of the A‐share market into the MSCI Index is one of the most influential events in the…

View details →DOI: 10.1155/2022/7623580Cited by 2
Negative / Null Result Report

Abstract 16996: Controlled Pauses (“Stutter”) CPR Did Not Improve ROSC or 4-hour Survival in a Porcine Model of VF-induced Cardiac Arrest

Alexander Esibov, Tyson G Taylor, Sharon B Melnick et al. · 2015 · Circulation

Introduction: Ischemic post-conditioning (IPC) has shown promise in mitigating ischemia-reperfusion injury. Controlled pauses during CPR (CP-CPR) following cardiac arrest (CA) and prolonged downtime may help invoke IPC mechanisms and have…

View details →DOI: 10.1161/circ.132.suppl_3.16996Cited by 2
Negative / Null Result Report

Rice yield in Costa Rican Central Pacific did not improve with a urease inhibitor

Ana Gabriela Pérez-Castillo, Weynner Giraldo-Sanclemente, Mayela Monge-Muñoz et al. · 2024 · Frontiers in Agronomy

Urea is widely used as nitrogen (N) source for rice fertilization in Costa Rica, despite its low efficiency linked to ammonia losses. To assess urea management alternatives, two field experiments were conducted in the Central Pacific…

View details →DOI: 10.3389/fagro.2024.1394143Cited by 2
Negative / Null Result Report

Selecting goats for juniper consumption did not improve their liver Phase I detoxification

John W Walker, Brian M Shoemake, Danilo G Quadros et al. · 2023 · Journal of Animal Science

Abstract A sodium pentobarbital-induced sleep time study was conducted on 15 adult intact male Boer × Spanish goats selected for high (J+, n = 7) or low (J−, n = 8) juniper consumption (estimated breeding values of 13.1 ± 1.0 and −14.3 ±…

View details →DOI: 10.1093/jas/skad180Cited by 2
Negative / Null Result Report

Rituxiamb Did Not Improve Clinical Outcomes In AIDS-Related Burkitt Lymphoma

Hideyuki Yamamoto, Shotaro Hagiwara, Yuki Kojima et al. · 2011 · Blood

Abstract Abstract 1629 Background: With the widespread use of highly active antiretroviral therapy (HAART), the prognosis of HIV infected subjects has been improved, even if with AIDS-related lymphoma. Burkitt lymphoma progresses very…

View details →DOI: 10.1182/blood.v118.21.1629.1629Cited by 2
Negative / Null Result Report

Did Recent Voice Reforms Improve Good Governance within the World Bank?

Jonathan R. Strand, Kenneth J. Retzl · 2016 · Development and Change

ABSTRACT Using the concept of good governance, this article assesses how voting rules in the World Bank Group's primary loan facility determine members’ ability to influence the formation of winning coalitions in the Executive Board. In…

View details →DOI: 10.1111/dech.12231Cited by 2
Negative / Null Result Report

Analysis of the Existing Statistically Significant Difference between the Indicators of the Initial and Final Measurement after the Implementation of a Comprehensive Programme of Sport Improvement in Orienteering for Students from the Technical University of Sofia, Plovdiv Branch

Daniel Vladimirov · 2025 · Strategies for Policy in Science and Education-Strategii na Obrazovatelnata i Nauchnata Politika

From December 2016 to December 2018, a comprehensive study was conducted to analyze the results of an advanced orienteering training and training program introduced. A comparative analysis was also used in the analysis of the research…

View details →DOI: 10.53656/str2025-2s-11-danCited by 1
Negative / Null Result Report

The “Mnemonic Time-Travel Effect”

Laura Mieth, Raoul Bell, Axel Buchner · 2019 · Experimental Psychology

Abstract. This registered report aims at replicating the so-called “mnemonic time-travel” effect. Aksentijevic, Brandt, Tsakanikos, and Thorpe (2019) reported that memory was improved when their participants experienced backward motion…

View details →DOI: 10.1027/1618-3169/a000461Cited by 1
Failed Experiment Report

Hybrid of Least Significant Bits and most Significant Bits for Improving Security and Quality of Digital Image Steganography

Abubakar Aminu Mu’azu, Kauthar Kabir · 2023 · WSEAS TRANSACTIONS ON COMPUTERS

The Security of confidential communication is protected using the most popular type of carrier to hold information known as Image steganography. The Least Significant Bit (LSB) algorithm and the Most Significant Bit (MSB) algorithm are…

View details →DOI: 10.37394/23205.2023.22.29Cited by 1
Negative / Null Result Report

Effect of biotin starvation on gene expression in industrially significant yeast Komagataella phaffii

Anastasia S. Makeeva, Anton V. Sidorin, Valeriia V. Ishtuganova et al. · 2023 · Ecological genetics

Komagataella phaffii(Pichia pastoris) is known to be an excellent producer of recombinant proteins for industrial and research purposes. Protein synthesis improvement in this yeast includes selection of optimal cultivation parameters [1,…

View details →DOI: 10.17816/ecogen568379Cited by 1
Negative / Null Result Report

192 Abundance of rumen methanogens did not differ in cattle that differed in residual feed intake

Harvey C Freetly, Amanda K Lindholm-Perry, Andrew P Foote et al. · 2020 · Journal of Animal Science

Abstract Methane represents an energetic loss, and it has been proposed that its reduction may be associated with improved feed efficiency. Rumen methanogens produce most of the methane. Forty-nine crossbred heifers were individually fed a…

View details →DOI: 10.1093/jas/skaa278.274Cited by 1
Negative / Null Result Report

School leadership and organizational change: does teacher innovative behaviour play a significant role?

Grace Damptey Manu, Michael Osei Aboagye, Seth Yeboah Ntim et al. · 2025 · International Journal of Educational Management

Purpose The implementation of school improvement initiatives – such as Ghana’s standards-based curriculum (SBC) – necessitates transformational and contextually responsive school leadership. In line with this, the recent primary school…

View details →DOI: 10.1108/ijem-09-2024-0531Cited by 1
Negative / Null Result Report

A novel approach to off-clamp partial nephrectomy demonstrates significant improvements in renal injury in an experimental porcine model

Daniel Olvera-Posada, Shouzhe Lin, Ghaleb Aboalsamh et al. · 2017 · Canadian Urological Association Journal

Introduction: We sought to design a partial nephrectomy (PN) with contralateral total nephrectomy porcine model and assess the underlying mechanisms of ischemia reperfusion injury (IRI) after PN using a novel, clinically approved resection…

View details →DOI: 10.5489/cuaj.4305Cited by 1
Negative / Null Result Report

Outcome of Second Line Treatment in Patients with Chronic Lymphocytic Leukemia Did Not Improve 2002-2013: A Population-Based Study from a Well-Defined Geographic Region

Anna Asklid, Agnes Mattsson, Einar Björgvinsson et al. · 2015 · Blood

Abstract Background: Treatment of relapsed or refractory (R/R) chronic lymphocytic leukemia (CLL) remains challenging. Major progress has been achieved with new agents such as ibrutinib and idelalisib. However relapses still occur with…

View details →DOI: 10.1182/blood.v126.23.4166.4166Cited by 1
Negative / Null Result Report

Abstract 191: Alcohol Consumption Before Injury Did Not Improve Neurological Outcomes In Patients With Severe Traumatic Brain Injury: A Nationwide, Retrospective Cohort Study

Tsuyoshi Nojima, Hiromichi Naito, Takashi Hongo et al. · 2022 · Circulation

Introduction: Traumatic brain injury (TBI) is a major global public health concern. Notably, alcohol may confer neuroprotective effects by inhibiting of N-methyl-D-aspartate receptors; however, the impact of alcohol exposure before injury…

View details →DOI: 10.1161/circ.146.suppl_1.191Cited by 1
Negative / Null Result Report

“Simple mechanical devices did not improve pelvis positioning in AP pelvis radiographs for reliable assessment of the acetabular orientation”

Matthias Brockmeyer, Sebastian Lott, Jonas Stroeder et al. · 2019 · Journal of Experimental Orthopaedics

Abstract Background The aim of this study was to develop two simple positioning devices for anteroposterior pelvis radiographs and to evaluate their effect on accuracy of the radiographs for assessment of the acetabular orientation…

View details →DOI: 10.1186/s40634-019-0191-7Cited by 1
Negative / Null Result Report

An impedance threshold device did not improve carotid blood flow in a porcine model of prolonged cardiac arrest

Benedict Kjaergaard, Hans O. Holdgaard, Sigridur O. Magnusdottir et al. · 2020 · Journal of Translational Medicine

Abstract Background An impedance threshold device (ITD) was developed to increase venous return to the heart and therefore increase cardiac output and organ blood flow during cardiopulmonary rescue (CPR). Basic CPR aims to maintain…

View details →DOI: 10.1186/s12967-020-02264-5Cited by 1
Negative / Null Result Report

Soil biological and physical measurements did not improve the predictability of corn response to phosphorus fertilization

Ben Groebner, Jason D. Clark, Jeffrey D. Svedin et al. · 2024 · Agronomy Journal

Abstract Including soil health and physical measurements with traditional soil fertility measurements has the potential to improve corn ( Zea mays L.) P fertilizer recommendations. The objectives for this study were to (1) evaluate the…

View details →DOI: 10.1002/agj2.21612Cited by 1
Negative / Null Result Report

Patient leaflets on respiratory tract infections did not improve shared decision making and antibiotic prescriptions in a low-prescriber setting

Andreas Plate, Stefania Di Gangi, Christian Garzoni et al. · 2024 · Scientific Reports

Abstract Patient information leaflets can reduce antibiotic prescription rates by improving knowledge and encouraging shared decision making (SDM) in patients with respiratory tract infections (RTI). The effect of these interventions in…

View details →DOI: 10.1038/s41598-024-55166-7Cited by 1
Negative / Null Result Report

Did the Staging of Renal Neoplasm Improve with Time? Retrospective Study on a Cohort of 2000 Patients

Nicola Arrighi, Alessandro Antonelli, Tiziano Zanotelli et al. · 2011 · Urologia Journal

Objectives During the last 3 decades ultrasonographic and cross-sectional imaging techniques have been widely adopted in the pre-operative staging of renal masses with a progressive technological refinement. The aim of this study is to…

View details →DOI: 10.5301/ru.2011.8521Cited by 1
Negative / Null Result ReportOpen accessComputer Science

PluriHopRAG: Exhaustive, Recall-Sensitive QA Through Corpus-Specific Document Structure Learning

Mykolas Sveistrys, Richard Kunert · 2025 · arXiv

Retrieval-Augmented Generation (RAG) has been used in question answering (QA) systems to improve performance when relevant information is in one (single-hop) or multiple (multi-hop) passages. However, many real life scenarios (e.g. dealing with financial, legal, medical reports) require checking all documents for relevant information without a clear stopping condition. We term these pluri-hop questions, and formalize them by 3 conditions - recall sensitivity, exhaustiveness, and exactness. To study this setting, we introduce PluriHopWIND, a multilingual diagnostic benchmark of 48 pluri-hop que

Negative / Null Result ReportOpen accessPhysics

Incorporating intrinsic compressibility effects in velocity transformations for wall-bounded turbulent flows

Asif Manzoor Hasan, Johan Larsson, Sergio Pirozzoli et al. · 2023 · arXiv

A transformation that relates a compressible wall-bounded turbulent flow with non-uniform fluid properties to an equivalent incompressible flow with uniform fluid properties is derived and validated. The transformation accounts for both variable-property and intrinsic compressibility effects, the latter being the key improvement over the current state-of-the-art. The importance of intrinsic compressibility effects contradicts the renowned Morkovin's hypothesis.

Replication FailureOpen accessComputer Science

Quantum Corrections to Baryon Properties in Chiral Soliton Models

Frank Meier, Hans Walliser · 1996 · arXiv

We present a procedure to calculate 1-loop graphs in the soliton sector of chiral Lagrangians and use it to calculate quantum corrections to certain baryon observables in Skyrme-type models. Results generally show an improvement over the values obtained in tree approximation except for the case of the axial coupling g_A.

Negative / Null Result ReportOpen accessComputer Science

WiFi-based Global Localization in Large-Scale Environments Leveraging Structural Priors from osmAG

Xu Ma, Jiajie Zhang, Fujing Xie et al. · 2025 · arXiv

Global localization is essential for autonomous robotics, especially in indoor environments where the GPS signal is denied. We propose a novel WiFi-based localization framework that leverages ubiquitous wireless infrastructure and the OpenStreetMap Area Graph (osmAG) for large-scale indoor environments. Our approach integrates signal propagation modeling with osmAG's geometric and topological priors. In the offline phase, an iterative optimization algorithm localizes WiFi Access Points (APs) by modeling wall attenuation, achieving a mean localization error of 3.79 m (35.3\% improvement over tr