Replication FailureMedicine
Rice WM, Shaw AP, Britt RC et al. · 2026 · Journal of the American College of Surgeons
Background Rising patient volumes and an aging population are leading to difficulties in providing timely surgical intervention in emergency general surgery (EGS). With decreased resilience and greater comorbidity burden, we hypothesized…
View details →DOI: 10.1097/xcs.0000000000001749 Negative / Null Result ReportMedicine
Pohjola A, Asikainen A, Kaprio J et al. · 2026 · Neurology
Background and objectives The growing use and improved accessibility of noninvasive imaging modalities have increased the detection of incidental intracranial findings, such as unruptured brain arteriovenous malformations (AVMs). At the…
View details →DOI: 10.1212/wnl.0000000000214724 Negative / Null Result Report
Gautier R, Latinus M, Briend F · 2025 · Preprint
The Heartbeat Evoked Potential (HEP) is a potential marker of cardiac signal integration at the cerebral level, obtained by averaging epochs time-locked to the ECG R-peaks. The HEP is modulated across different experimental conditions with…
View details →DOI: 10.22541/au.174728739.94643983/v1 Negative / Null Result ReportOpen accessMedicine
Harada S, Teraoka R, Kuroda N et al. · 2026 · Experimental brain research
This study investigated audiovisual integration in visual motion perception among both younger and older adults. Participants were asked to discriminate the visual motion direction of a random dot kinematogram in two experiments. The…
View details →DOI: 10.1007/s00221-026-07286-x Negative / Null Result ReportMedicine
Clark KA, Nielsen S, Heywood T et al. · 2024 · Journal of clinical densitometry : the official journal of the International Society for Clinical Densitometry
The Craig's test is a clinical assessment used to quantify femoral version. The validity of the Craig's test has been called into question due to instances where the test exhibits relatively poor correlation with three-dimensional imaging.…
View details →DOI: 10.1016/j.jocd.2024.101466 Negative / Null Result ReportOpen accessMedicine
Khurana A, Chai N, Gibson A et al. · 2025 · Abdominal radiology (New York)
Objectives Liver transplant (LT) is an effective treatment for hepatocellular carcinoma (HCC) in appropriately selected patients. Locoregional therapy (LRT) is often performed to extend a patient's eligibility for LT. Imaging has a modest…
View details →DOI: 10.1007/s00261-025-04811-4 Negative / Null Result ReportMedicine
Mallette JH, Crudup BF, Oudomrath Speyrer A et al. · 2026 · Journal of applied physiology (Bethesda, Md. : 1985)
The biological effects of chronic estrogen supplementation on renal function and injury with aging in men are unknown. Using an experimental model of feminizing hormone therapy (FHT) induced by 17β-estradiol (E2) (5 mg/kg sc)…
View details →DOI: 10.1152/japplphysiol.00052.2026 Negative / Null Result ReportOpen accessMedicine
Yasuhara M, Nambu I · 2025 · Frontiers in human neuroscience
Humans achieve efficient behaviors by perceiving and responding to errors. Error-related potentials (ErrPs) are electrophysiological responses that occur upon perceiving errors. Leveraging ErrPs to improve the accuracy of brain-computer…
View details →DOI: 10.3389/fnhum.2025.1516721 Negative / Null Result ReportOpen accessMedicine
Gautier R, Latinus M, Briend F · 2025 · Psychophysiology
The heartbeat evoked potential (HEP) is a potential marker of cardiac signal integration at the cerebral level, obtained by averaging epochs time-locked to the ECG R-peaks. The HEP is modulated across different experimental conditions with…
View details →DOI: 10.1111/psyp.70206 Negative / Null Result ReportOpen accessMedicine
Springer-Sapp CB, Ogbara OO, Addison O et al. · 2025 · The Journal of frailty & aging
Background The progression of sarcopenia with aging may be related to mitochondrial dysfunction due in part to altered mitochondrial dynamics (fusion, fission, mitophagy, and biogenesis). Previous work has identified altered expression of…
View details →DOI: 10.1016/j.tjfa.2025.100090 Negative / Null Result ReportMedicine
Khan F, Pandit D, Lalan S et al. · 2026 · Biomedical physics & engineering express
Alzheimer's disease (AD) classification using machine learning has increasingly relied on multimodal inputs such as Magnetic Resonance Imaging (MRI), cognitive assessments, and biological markers. This study evaluates whether integrating…
View details →DOI: 10.1088/2057-1976/ae4630 Negative / Null Result Report
Toth R, Parry DA, Pourafshari R et al. · 2025 · Preprint
Research suggests that a large portion of media use is driven by habit. Yet our ability to measure habitual processes directly remains limited, suggesting that more naturalistic methods are needed. Leveraging a deep mobile event log and…
View details →DOI: 10.31234/osf.io/bqfne_v3 Negative / Null Result Report
Toth R, Parry DA, Pourafshari R et al. · 2025 · Preprint
Research suggests that a large portion of media use is driven by habit. Yet our ability to measure habitual processes directly remains limited, suggesting that more naturalistic methods are needed. Leveraging a deep mobile event log and…
View details →DOI: 10.31234/osf.io/bqfne_v1 Negative / Null Result ReportMedicine
Paul RL, Porter DC, Mutschler-Aldine S et al. · 2026 · Environmental entomology
Evaluation of potential classical biological control agents typically begins with laboratory testing for their fundamental host range. These experiments are intended to evaluate the propensity for nontarget attack but often do so in highly…
View details →DOI: 10.1093/ee/nvaf125 Negative / Null Result ReportOpen accessMedicine
Ryan E, Norynberg K, Connor P et al. · 2026 · Journal of medical radiation sciences
Introduction Patient contact shielding has been used in paediatric radiography as standard practice for decades. Contemporary evidence no longer supports its use in routine clinical practice. The Medical Imaging Department of an Australian…
View details →DOI: 10.1002/jmrs.70053 Negative / Null Result Report
Armand M, Zeilmann L, Weinzettl C et al. · 2025 · Preprint
Abstract To attract pollinators, flowering plants evolve diverse sensory traits into compelling signals. Floral scent, in particular, plays a key role in drawing bees from a distance and shaping their foraging choices. Scent composition…
View details →DOI: 10.21203/rs.3.rs-6292403/v1 Negative / Null Result Report
Armand M, Zeilmann L, Weinzettl C et al. · 2025 · Preprint
ABSTRACT To attract pollinators, flowering plants evolve diverse sensory traits into compelling signals. Floral scent, in particular, plays a key role in drawing bees from a distance and shaping their foraging choices. Scent composition…
View details →DOI: 10.1101/2025.03.15.643418 Negative / Null Result Report
Hossain M, Poot P, Veneklaas E · 2025 · Preprint
Summary It is often stated that trees experiencing climate change may be more vulnerable to damaging effects of pest and disease, but experimental tests are still rare. In this study, we examined the separate and combined impact of…
View details →DOI: 10.1101/2025.03.03.641225 Negative / Null Result Report
Varkentin E, Brich IR, Sünkel U et al. · 2025 · Preprint
Narrative comprehension, a cognitive skill essential for social participation, relies on a range of abilities, including memory and inference-making. While aging-related cognitive changes are well-documented, research on narrative…
View details →DOI: 10.31234/osf.io/knpv5_v2 Negative / Null Result ReportMedicine
Li H, Yang L, Luo C et al. · 2025 · Environmental pollution (Barking, Essex : 1987)
Soil microplastics (MPs) are a substantial threat to soil health, particularly by disrupting soil aggregation. Additionally, MPs undergo aging processes in the soil, which may significantly alter their long-term impacts on soil structure.…
View details →DOI: 10.1016/j.envpol.2025.125655 Negative / Null Result Report
paban v, Feraud L, Weills A et al. · 2024 · Preprint
In the context of an aging population, concerns surrounding memory function become increasingly prevalent, particularly as individuals transition into middle age and beyond. This study investigated neurofeedback (NFB) as a potential early…
View details →DOI: 10.22541/au.172480012.24819730/v1 Negative / Null Result ReportMedicine
Gordon P, Urquhart E, Oad S et al. · 2024 · Australian health review : a publication of the Australian Hospital Association
Objective To assess whether prostate biopsy rates have altered with the July 2018 change in Australian Medicare Benefits Schedule (MBS) rebates supporting multiparametric magnetic resonance imaging (mpMRI) for diagnosing prostate cancer.…
View details →DOI: 10.1071/ah24024 Negative / Null Result ReportOpen accessMedicine
Chibaudel B, Dourthe LM, André T et al. · 2026 · Signal transduction and targeted therapy
Managing unresectable metastatic colorectal cancer (mCRC) requires a comprehensive strategy. While chemotherapy, anti-angiogenic, and anti-epidermal growth factor receptor (EGFR) agents are available, strategy trials are needed to optimize…
View details →DOI: 10.1038/s41392-026-02639-y Negative / Null Result ReportMedicine
Rhee H, Henderson LM, Bauer RN et al. · 2024 · Allergy
Background Tryptase, a mast cell protease, has been identified as a potential therapeutic target in managing patients with refractory asthma. We assessed the efficacy, safety, pharmacokinetics, and pharmacodynamics of MTPS9579A, an…
View details →DOI: 10.1111/all.16309 Negative / Null Result ReportMedicine
Putzer M, De Decker S, Gutierrez Quintana R et al. · 2026 · Journal of feline medicine and surgery
ObjectivesThe underlying aetiology of feline idiopathic vestibular syndrome (IVS) remains unclear. In humans, specific magnetic resonance imaging (MRI) sequences are used to demonstrate differences in endolymph composition between…
View details →DOI: 10.1177/1098612x261445137 Negative / Null Result ReportMedicine
Rashad Ali F, Teiba MK, Sheha AS et al. · 2026 · Clinical radiology
Background and purpose Magnetic susceptibility levels of multiple sclerosis plaques increase as they convert from the active enhancing stage to the chronic or inactive nonenhancing stages. The purpose of our study was to discern whether a…
View details →DOI: 10.1016/j.crad.2025.107127 Negative / Null Result ReportMedicine
Suzuki K, Sato H, Sorimachi T et al. · 2025 · Neurosurgical review
Older age and Fisher group scores predict poor outcomes in patients with aneurysmal subarachnoid hemorrhage (aSAH). However, among aging societies, treatment indications and decisions in older patients with severe-grade aSAH (World…
View details →DOI: 10.1007/s10143-025-03638-3 Negative / Null Result ReportMedicine
Fitzgerald M · 2024 · Trends in Food Science & Technology.
The messaging around processed food recently is that it is unhealthy and associated with the onset of chronic disease. However, food is processed for many reasons that range from preservation to safety, and then more recently in response…
Negative / Null Result ReportOpen accessMedicine
McEvoy LK, Zhang B, Nguyen S et al. · 2026 · Aging
Epigenetic clocks of biological aging have been associated with cognitive impairment and dementia. Less is known about whether they are associated with an older-appearing brain or with an atrophy pattern associated with dementia. We…
View details →DOI: 10.18632/aging.206369 Negative / Null Result ReportOpen accessMedicine
Wakayama T, Saita Y, Uchino S et al. · 2025 · Journal of clinical medicine
Objective: Platelet-rich plasma (PRP) therapy has become a popular treatment for knee osteoarthritis. We aimed to determine the outcomes of knee osteoarthritis patients following PRP therapy using magnetic resonance imaging (MRI) findings…
View details →DOI: 10.3390/jcm14186408 