A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.
1757 results in Negative / Null Result Report for "Mpro" · page 15 of 59
Christine Sandbach, Julie K. Young, Mary Conner et al. · 2024 · Restoration Ecology
Stream restoration programs employ beaver‐related restoration techniques, including beaver translocations and installation of beaver dam analogs (BDA), to create complex in‐stream habitat. We investigated whether BDA installations improved…
Rashmi Kumari, Lisa Willing · 2022 · Diabetology
Impaired glucocorticoid signaling in diabetes mellitus and its relation to suppressed immune function and hyperglycemia during acute stroke has been shown to be detrimental. Therefore, the aim of this study was to examine the effect of…
Özgül Düzgün, Pırıltı Özcan, Mehmet Faik Özçelik · 2022 · Journal of Personalized Medicine
ERAS is a protocol consisting of multidisciplinary approaches, including patient education, fluid resuscitation, keeping patients’ innormothermic state, early feeding, and mobilization. We aimed to present and compare the postoperative…
Xin Zhang, Yingming Zhu · 2025 · Sustainability
Chinese Emissions Trading Scheme (ETS) has been a crucial policy for China, a major manufacturing and carbon-emitting country, in achieving its “carbon neutrality” goals and sustainable development. This paper examines the performance of…
Hammad Sadiq, Sanjeev Rampam, Jay Patel et al. · 2022 · Medicine
Objectives: To assess the impact of a preoperative walking intervention on improving postoperative recovery in at-risk frail older adult patients. Study Type: Unblinded, randomized controlled trial which assigned patients to intervention…
Briana N. Sprague, Anna K. Forster · 2025 · Healthcare
Objective: What types of multilevel interventions exist to improve blood pressure among community-dwelling adults aged 18+ in the United States? What is the treatment efficacy? Data Source: Peer-reviewed articles from Cochrane Library,…
Malik E. Juweid, Dana Alselaibi, Hiba Abandeh et al. · 2023 · Medicine
Trabecular bone score (TBS) assesses trabecular microarchitecture at the lumbar spine and was shown to improve fracture risk prediction compared to bone mineral density (BMD) alone. We investigated whether lumbar degenerative changes (DC)…
Richard H. Epstein, Franklin Dexter, Brenda G. Fahy · 2023 · Anesthesia & Analgesia
BACKGROUND: In a recent study, rapid response team implementation at 1 hospital was associated with only a 0.1% reduction in inpatient mortality from 2005 to 2018, characterized in the accompanying editorial as a “tepid” improvement. The…
Brooke D Goodman, Kyle A Lima, Seth Benz et al. · 2025 · Ornithological Applications
Abstract Point counts are integral to bird population monitoring, and multiple methods have been developed to improve their reliability. These methods include multiple-observer protocols, double-sampling, and surveys using autonomous…
Sehoon Park, Yisak Kim, Chung Hee Baek et al. · 2025 · Kidney Research and Clinical Practice
Background: Immunoglobulin A nephropathy (IgAN) is a major cause of end-stage kidney disease (ESKD). The International IgA Nephropathy Prediction Tool (IIgAN-PT) predicts IgAN prognosis, but improvement in the prediction performance using…
Priyanka Majumder, Apu Kumar Saha · 2019 · International Journal of Energy Optimization and Engineering
The operational performance of hydropower plants (HPPs) is largely affected as the output from the plant entirely depends on the rainfall and demand from consumers both of which are compromised due to the vulnerability in climatic patterns…
Benjamin Uzochukwu, Tolib Mirzoev, Chinyere Okeke et al. · 2020 · International Journal of Health Policy and Management
Background: During 2012-2015, the Federal Government of Nigeria launched the Subsidy Reinvestment and Empowerment Programme, a health system strengthening (HSS) programme with a Maternal and Child Health component (Subsidy Reinvestment and…
Vinnycius Nunes de Oliveira, Ricardo Borges Viana, João Victor Rosa de Freitas et al. · 2024 · BMC Sports Science, Medicine and Rehabilitation
Abstract This study evaluated the acute effect of the exergame Kinect Sports ® beach volleyball on state anxiety level in adult women. Thirty healthy adult women (age: 21 [4] years, body mass: 54.70 [19.50] kg, height: 1.61 ± 0.05 m, and…
Jing Wu · 2022 · Wireless Communications and Mobile Computing
Chinese A‐shares were officially included in the Morgan Stanley Capital International (MSCI) Emerging Markets Index from June 2018. The inclusion of the A‐share market into the MSCI Index is one of the most influential events in the…
Erin Penno, Carol Atmore, Brett Maclennan et al. · 2023 · BMJ Open
Objectives In Aotearoa New Zealand (NZ), integration across the healthcare continuum has been a key approach to strengthening the health system and improving health outcomes. A key example has been four regional District Health Board (DHB)…
Alexander Esibov, Tyson G Taylor, Sharon B Melnick et al. · 2015 · Circulation
Introduction: Ischemic post-conditioning (IPC) has shown promise in mitigating ischemia-reperfusion injury. Controlled pauses during CPR (CP-CPR) following cardiac arrest (CA) and prolonged downtime may help invoke IPC mechanisms and have…
Rafael R. Maes, Geert Potters, Erik Fransen et al. · 2023 · Sustainability
Air quality currently poses a major risk for human health. Currently, diesel is widely used as fuel and is a significant source of nitrogen oxides (NOx) and particulate matter (PM), both hazardous to human health. A good alternative for…
Ana Gabriela Pérez-Castillo, Weynner Giraldo-Sanclemente, Mayela Monge-Muñoz et al. · 2024 · Frontiers in Agronomy
Urea is widely used as nitrogen (N) source for rice fertilization in Costa Rica, despite its low efficiency linked to ammonia losses. To assess urea management alternatives, two field experiments were conducted in the Central Pacific…
Jonathan R. Strand, Kenneth J. Retzl · 2016 · Development and Change
ABSTRACT Using the concept of good governance, this article assesses how voting rules in the World Bank Group's primary loan facility determine members’ ability to influence the formation of winning coalitions in the Executive Board. In…
John W Walker, Brian M Shoemake, Danilo G Quadros et al. · 2023 · Journal of Animal Science
Abstract A sodium pentobarbital-induced sleep time study was conducted on 15 adult intact male Boer × Spanish goats selected for high (J+, n = 7) or low (J−, n = 8) juniper consumption (estimated breeding values of 13.1 ± 1.0 and −14.3 ±…
Cheng-Hua Yang, Alex · 2015 · Journal of Air Transport Studies
Aviation safety has been affected greatly by technological improvements. A series of Ground Proximity Warning Systems (GPWSs) were developed to prevent accidents during Controlled Flight into Terrain (CFIT). This study analyzed the role of…
Hideyuki Yamamoto, Shotaro Hagiwara, Yuki Kojima et al. · 2011 · Blood
Abstract Abstract 1629 Background: With the widespread use of highly active antiretroviral therapy (HAART), the prognosis of HIV infected subjects has been improved, even if with AIDS-related lymphoma. Burkitt lymphoma progresses very…
Laura Mieth, Raoul Bell, Axel Buchner · 2019 · Experimental Psychology
Abstract. This registered report aims at replicating the so-called “mnemonic time-travel” effect. Aksentijevic, Brandt, Tsakanikos, and Thorpe (2019) reported that memory was improved when their participants experienced backward motion…
Guthrie Miller, John Klumpp, Deepesh Poudel · 2020 · Radiation Protection Dosimetry
Abstract Based on $n$ replicate measurements that require known normalization factors and assuming an underlying normal distribution for individual measurements but with unknown standard deviation, a combined likelihood function is derived…
Daniel Vladimirov · 2025 · Strategies for Policy in Science and Education-Strategii na Obrazovatelnata i Nauchnata Politika
From December 2016 to December 2018, a comprehensive study was conducted to analyze the results of an advanced orienteering training and training program introduced. A comparative analysis was also used in the analysis of the research…
Anastasia S. Makeeva, Anton V. Sidorin, Valeriia V. Ishtuganova et al. · 2023 · Ecological genetics
Komagataella phaffii(Pichia pastoris) is known to be an excellent producer of recombinant proteins for industrial and research purposes. Protein synthesis improvement in this yeast includes selection of optimal cultivation parameters [1,…
Harvey C Freetly, Amanda K Lindholm-Perry, Andrew P Foote et al. · 2020 · Journal of Animal Science
Abstract Methane represents an energetic loss, and it has been proposed that its reduction may be associated with improved feed efficiency. Rumen methanogens produce most of the methane. Forty-nine crossbred heifers were individually fed a…
Daniel Olvera-Posada, Shouzhe Lin, Ghaleb Aboalsamh et al. · 2017 · Canadian Urological Association Journal
Introduction: We sought to design a partial nephrectomy (PN) with contralateral total nephrectomy porcine model and assess the underlying mechanisms of ischemia reperfusion injury (IRI) after PN using a novel, clinically approved resection…
Grace Damptey Manu, Michael Osei Aboagye, Seth Yeboah Ntim et al. · 2025 · International Journal of Educational Management
Purpose The implementation of school improvement initiatives – such as Ghana’s standards-based curriculum (SBC) – necessitates transformational and contextually responsive school leadership. In line with this, the recent primary school…
Anna Asklid, Agnes Mattsson, Einar Björgvinsson et al. · 2015 · Blood
Abstract Background: Treatment of relapsed or refractory (R/R) chronic lymphocytic leukemia (CLL) remains challenging. Major progress has been achieved with new agents such as ibrutinib and idelalisib. However relapses still occur with…