459 results in Negative / Null Result Report for "randomized controlled trial" · page 14 of 16
Negative / Null Result ReportMedicine
Bieglecka, Kęszycka, Czerwińska et al. · 2026 · Nutrients
Patients with psoriasis, a non-contagious, chronic, systemic inflammatory skin disease, often suffer from carbohydrate metabolism disorders, which can exacerbate systemic inflammation. This randomized, double-blind, placebo-controlled…
View details →DOI: 10.3390/nu18121843 Negative / Null Result ReportMedicine
Gou, He, Zhuo · 2026 · Frontiers in medicine
To investigate the effect and safety of astragalus injection at Neiguan (PC6) for chronic heart failure (CHF; HF) with qi-deficiency and blood-stasis syndrome, and its effect on the renin-angiotensin-aldosterone system (RAAS). A…
View details →DOI: 10.3389/fmed.2026.1836620 Negative / Null Result ReportMedicine
Yang, Mueller, D'Andrea et al. · 2026 · Academic psychiatry : the journal of the American Association of Directors of Psychiatric Residency Training and the Association for Academic Psychiatry
Resident physicians experience high rates of depression, anxiety, burnout, and loneliness, yet few evidence-based interventions have been evaluated in this population. This randomized controlled pilot trial examined the feasibility,…
View details →DOI: 10.1007/s40596-026-02384-y Negative / Null Result ReportMedicine
Peng, Wang, Xiao et al. · 2026 · Journal of minimally invasive gynecology
To compare the effectiveness and safety of transvaginal natural orifice transluminal endoscopic surgery (vNOTES) pelvic reconstruction (PRC), vNOTES presacral-uterosacral ligament suspension (PULS), and sacrospinous ligament fixation…
View details →DOI: 10.1016/j.jmig.2026.06.024 Negative / Null Result ReportMedicine
Rocha, Dos Anjos, Pinho et al. · 2026 · Journal of dentistry
This 12-month, double-blind, parallel, randomized controlled trial compared the material fracture/retention rates of occluso-proximal direct composite resin restorations associated with polyethylene fiber (CR+PF; Ribbond®) with…
View details →DOI: 10.1016/j.jdent.2026.106863 Negative / Null Result ReportMedicine
Fuentes-Expósito, Frid, Muñoz-Mateu et al. · 2026 · JCO clinical cancer informatics
We evaluated whether offering access to a multicomponent mHealth app improves quality of life (QoL) and psychosocial outcomes among breast cancer survivors under pragmatic, nonprescriptive conditions. In this single-center, randomized,…
View details →DOI: 10.1200/cci-26-00025 Negative / Null Result ReportMedicine
Esposito, Bocari, Cho et al. · 2026 · The International journal of oral & maxillofacial implants
This multicenter randomized controlled trial compared the clinical effectiveness of 7.0-mm wide-diameter implants with 5.0-mm conventional-diameter implants placed immediately after molar extraction. Thirty-nine patients needing a single…
View details →DOI: 10.11607/jomi.11536 Negative / Null Result ReportMedicine
Ishiwatari, Nakahara, Kawaguchi et al. · 2026 · Gastrointestinal endoscopy
Endoscopic retrograde cholangiopancreatography with metal stent (MS) placement is the standard treatment for biliary drainage in patients with unresectable pancreatic cancer. A 10-mm diameter MS is generally used; however, a larger stent…
View details →DOI: 10.1016/j.gie.2026.06.037 Negative / Null Result ReportMedicine
Villalón López, Escaffi-Schwarz · 2026 · Journal of medical Internet research
Parental burnout is an underrecognized syndrome characterized by emotional exhaustion, detachment from children, and reduced parental efficacy. It is associated with sleep disturbance, addictive behaviors, suicidal ideation, and increased…
View details →DOI: 10.2196/87416 Negative / Null Result ReportMedicine
Mokhtar, Gawish, Abdelgawad et al. · 2026 · Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA
To compare the clinical and radiological outcomes of anterior cruciate ligament reconstruction (ACLR) augmented with platelet-rich plasma (PRP) (1) or bone marrow aspirate concentrate (BMAC) (2) against a control group undergoing standard…
View details →DOI: 10.1002/ksa.70484 Negative / Null Result ReportMedicine
Jiang, Wang, Wei et al. · 2026 · Geriatric nursing (New York, N.Y.)
Peripheral Intravenous Cannulas (PIVCs) are extensively used for infusion therapy. Although current evidence suggests that adult patients may have PIVCs removed based on clinical indications, the indication in elderly patients remains…
View details →DOI: 10.1016/j.gerinurse.2026.104100 Negative / Null Result ReportMedicine
Rathee, Bhardwaj, Gupta et al. · 2026 · International journal of clinical pediatric dentistry
Anxiety and pain often lead to a challenging situation in a dental clinic. This study aimed to compare the efficacy of virtual reality (VR) glasses to conventional techniques for anxiety control in children. Jio Dive VR glasses (passive)…
View details →DOI: 10.5005/jp-journals-10005-3493 Negative / Null Result ReportMedicine
Le, Chotikkakamthorn, Kasetsuwan et al. · 2026 · Clinical ophthalmology (Auckland, N.Z.)
This study aims to compare the effect of meibomian gland expression (MGX) combined with lid hygiene versus lid hygiene alone on the meibomian gland's morphology and function for obstructive meibomian gland dysfunction (oMGD). In this…
View details →DOI: 10.2147/opth.s607078 Negative / Null Result ReportMedicine
van Keulen, Voogt, Kleinjan et al. · 2026 · JMIR mHealth and uHealth
Excessive alcohol consumption among adolescents and young adults is a serious health problem. Dynamically tailored interventions could reduce their excessive drinking. We therefore developed "What Do You Drink" (WDYD), a 17-week…
View details →DOI: 10.2196/68468 Negative / Null Result ReportMedicine
Wang, Li, Zhang et al. · 2026 · Child development
This study examines how center-based parenting interventions aimed at improving early child development in rural China affect the mental health of caregivers. Data from an analytic sample of 615 caregiver-child dyads (children aged 6 to 24…
View details →DOI: 10.1093/chidev/aacag099 Negative / Null Result ReportMedicine
Erdoğan, Ayaz-Alkaya · 2026 · Nurse education in practice
To evaluate the effect of crossword puzzle activities on nursing students' willingness to work with older adults and their competence in gerontological nursing. Although crossword puzzles are widely used learning tools, their effects in…
View details →DOI: 10.1016/j.nepr.2026.104844 Negative / Null Result ReportMedicine
Serttas, Uysal, Deği̇rmenci̇ et al. · 2026 · Injury
Urinary tract infection(UTI) is a common complication following hip fracture surgery in elderly patients. Urinary catheterization is frequently used to improve patient comfort during prolonged preoperative immobilization; however, its…
View details →DOI: 10.1016/j.injury.2026.113449 Negative / Null Result ReportMedicine
Peng, Wang, Gong et al. · 2026 · International ophthalmology
To compare the outcomes of conjunctival graft (CAG) versus limbal-conjunctival autograft (LCAG) in preventing recurrence after surgery for recurrent pterygium with intraoperative application of 0.02% mitomycin C(MMC). This prospective…
View details →DOI: 10.1007/s10792-026-04121-8 Negative / Null Result ReportMedicine
de Azevedo Ferreira, Fitz, Gimenez et al. · 2026 · International urogynecology journal
Seventy percent of women with pelvic floor muscle (PFM) dysfunction are unable to contract these muscles correctly. Instruction to contract properly is essential for effective PFM training (PFMT). The study aimed to compare two…
View details →DOI: 10.1007/s00192-026-06775-5 Negative / Null Result ReportOpen accessMedicine
Abdelkader AM, Osama H, Hassan ES et al. · 2026 · European journal of clinical pharmacology
Purpose Gliflozins (SGLT2 inhibitors) and statins are key treatments commonly used in patients with ischemic heart failure. Although both are well known for diminishing cardiovascular risk and heart failure-related mortality, the possible…
View details →DOI: 10.1007/s00228-026-04050-6 Negative / Null Result ReportMedicine
Çi̇men HN, Uğur S, Çıralı A et al. · 2026 · Nurse education in practice
Aim The aim of this study was to evaluate the effect of podcast-based educational content delivered to students on their knowledge, awareness and anxiety levels regarding Human Papillomavirus (HPV). Method This randomized controlled…
View details →DOI: 10.1016/j.nepr.2026.104902 Negative / Null Result ReportOpen accessMedicine
Ruengsiriphakakul S, Bumrerraj S, Thaenkham T · 2026 · Journal of education and health promotion
Background Iodine deficiency remains a global public health problem. Urinary iodine concentration (UIC) in pregnant women is a key indicator of iodine status in the population. Knowledge (K), attitude (A), and practice (P) levels of…
View details →DOI: 10.4103/jehp.jehp_815_25 Negative / Null Result ReportOpen accessMedicine
Abjar R, NasiriFormi E, Kazemi AH et al. · 2026 · Health science reports
Background and aims High-quality sleep, calmness, and lack of fatigue are vital for the health of critical hospital staff. Operating room personnel experience significant mental and physical stress, including anxiety and sleep…
View details →DOI: 10.1002/hsr2.72680 Negative / Null Result ReportOpen accessMedicine
Gonultas D, Kulcu DG, Kaymaz EP et al. · 2026 · Turkish journal of physical medicine and rehabilitation
Objectives This study aims to investigate the effectiveness of mesotherapy in patients with acute or subacute neck pain compared to oral medications with the same active ingredients. Patients and methods In this randomized, single-blind…
View details →DOI: 10.5606/tftrd.2025.16956 Negative / Null Result ReportOpen accessMedicine
Gao J, Hu CC, Wang XY et al. · 2026 · Frontiers in medicine
Background Perinatal sleep disturbance is highly prevalent among women undergoing elective cesarean section. Dexmedetomidine has been proven effective in improving sleep quality in patients undergoing general surgery, and this study aimed…
View details →DOI: 10.3389/fmed.2026.1823100 Negative / Null Result ReportMedicine
Haidar M, Raslan N · 2026 · Scientific reports
The use of local anesthesia is essential for pain control during the treatment of MIH-affected molars. This study aimed to compare injection-related pain and anesthetic efficacy between 2% lidocaine with epinephrine (LE) and 4% articaine…
View details →DOI: 10.1038/s41598-026-54698-4 Negative / Null Result ReportOpen accessMedicine
Alsaid HM, Khadour YA, Zakaria HM et al. · 2026 · Journal of musculoskeletal & neuronal interactions
Objectives This study evaluated the effect of sensory re-education on quality of life and sensation in patients with post-COVID-19 polyneuropathy. Methods Forty patients with post-COVID-19 polyneuropathy were randomly assigned to a study…
Negative / Null Result ReportMedicine
Kacaroglu Vicdan A, Gibyeli Genek D · 2026 · BMC complementary medicine and therapies
Background Hemodialysis often leads to various physiological, psychological, and social challenges for individuals receiving this treatment. This study was conducted to determine the effects of stress ball use on stress, sleep quality, and…
View details →DOI: 10.1186/s12906-026-05429-9 Negative / Null Result ReportMedicine
Moranne O, Gerbal M, Chkair S et al. · 2026 · Blood purification
Introduction This single center randomized controlled trial (NCT03562754) compared pre-diluted IHDF (PIHDF) without systemic anticoagulation and the Prometheus system with regional citrate anticoagulation (IHD-RCA) in high-bleeding-risk…
View details →DOI: 10.1159/000552412 Negative / Null Result ReportOpen accessMedicine
Patel DM, Wilson RF, Gharibani T et al. · 2026 · Journal of patient-reported outcomes
BACKGROUND: Patient-reported outcomes (PROs) are key outcomes of importance for people with chronic kidney disease (CKD), and may be of even higher relevance for patients with concomitant anemia which can often be symptomatic. Thus, PROs…
View details →DOI: 10.1186/s41687-026-01007-2 