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Failure-mode index

Search what already failed

A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.

1757 results in Negative / Null Result Report for "Mpro" · page 14 of 59

Negative / Null Result Report

Education Finance Reform and the Great Recession: Did State Policy and Fiscal Federalism Improve Education Spending, School Resources, and Student Achievement in Pennsylvania?

Matthew P. Steinberg, Rand Quinn, J. Cameron Anglum · 2020 · Journal of Education Finance

abstract: We estimate the impact of school finance reform on adequate and equitable district spending, school resources and student achievement in Pennsylvania. From the 2008-09 to the 2010-11 school years, amid the Great Recession,…

View details →DOI: 10.1353/jef.2020.a760723Cited by 6
Negative / Null Result Report

Did School Meal Programs and SNAP Participation Improve Diet Quality of US Children from Low-Income Households: Evidence from NHANES 2013–2014?

Tzuan A. Chen, Lorraine R. Reitzel, Ezemenari M. Obasi et al. · 2021 · Nutrients

Nutrition assistance programs such as school meals and the Supplemental Nutrition Assistance Program (SNAP) are designed to provide a safety net for the dietary intake of children from low-income families. However, compared with eligible…

View details →DOI: 10.3390/nu13103574Cited by 6
Negative / Null Result Report

Cover crops did not improve soil health but hydroclimatology may guide decisions preventing cash crop yield loss

Debankur Sanyal, Avik Mukherjee, Amin Rahhal et al. · 2023 · Frontiers in Soil Science

Introduction Cover crop (CC) is an essential tool to improve or maintain soil health, potentially improving cash crop productivity. Several recent reports of cash crop yield reduction following cover cropping necessitated this research to…

View details →DOI: 10.3389/fsoil.2023.1111821Cited by 6
Negative / Null Result Report

Did expanded access to denture services improve chewing ability in the Korean older population? Results of a regression discontinuity analysis

Nam-Hee Kim, Ichiro Kawachi · 2020 · Scientific Reports

Abstract The Korean National Health Insurance expanded the dental insurance in 2012 to cover denture services for older adults. We analyzed whether the new policy improved of chewing ability in the eligible population. We used regression…

View details →DOI: 10.1038/s41598-020-68189-7Cited by 6
Negative / Null Result Report

Multimodal analgesia did not improve post‐operative pain scores, reduce opioid consumption or reduce length of stay following hip arthroscopy

Ryan M. Degen, Andrew Firth, Herman Sehmbi et al. · 2023 · Knee Surgery, Sports Traumatology, Arthroscopy

Abstract Purpose To determine whether different regimens of multimodal analgesia will reduce postoperative pain scores, opioid consumption, costs and hospital length‐of‐stay following hip arthroscopy. Methods From 2018 to 2021, 132…

View details →DOI: 10.1007/s00167-023-07445-5Cited by 5
Negative / Null Result Report

STABILIZER

Charlie Curtsinger, Emery D. Berger · 2013 · ACM SIGPLAN Notices

Researchers and software developers require effective performance evaluation. Researchers must evaluate optimizations or measure overhead. Software developers use automatic performance regression tests to discover when changes improve or…

View details →DOI: 10.1145/2499368.2451141Cited by 5
Negative / Null Result Report

Challenging the understanding of significant improvement and outcome in schizophrenia – the concept of reliable and clinically significant change methods

Rebecca Schennach, Hans‐Jürgen Möller, Michael Obermeier et al. · 2015 · International Journal of Methods in Psychiatric Research

Abstract Significant changes of schizophrenia patients during inpatient treatment were evalutaed and compared to established outcome criteria. The concept of reliable and clinically significant change methods was applied to three hundred…

View details →DOI: 10.1002/mpr.1476Cited by 5
Negative / Null Result Report

Supplementation of graded levels of rumen-protected choline to a pelleted total mixed ration did not improve the growth and slaughter performance of fattening lambs

Qin Huo, Xuezhao Sun, Tingting Wu et al. · 2022 · Frontiers in Veterinary Science

Choline is an essential nutrient in ruminant diets, which contributes to the fundamental biological functions of the animal. However, choline is easily degraded in the rumen before it can be absorbed. Rumen-protected choline (RPC)…

View details →DOI: 10.3389/fvets.2022.1034895Cited by 5
Negative / Null Result Report

Partial replacement of soybean meal with full-fat black soldier fly larvae meal in plant-based nursery diets did not influence fecal Escherichia coli colony forming units or improve fecal consistency when pigs were weaned into non-disinfected pens

B Christensen, C Zhu, M Niazy et al. · 2023 · Translational Animal Science

Abstract At weaning, one hundred pigs (21 d of age; 6.96 ± 0.23 kg BW) were used to determine the effect of partially replacing soybean meal (SBM) in corn- and SBM-based nursery diets on growth performance, fecal scores, Escherichia coli…

View details →DOI: 10.1093/tas/txad121Cited by 5
Negative / Null Result Report

Supplementing rumen‐protected methionine to lactating multiparous dairy cows did not improve reproductive performance

David Süss, Michael Iwersen, Vanessa Schweinzer et al. · 2019 · Reproduction in Domestic Animals

Abstract There is evidence that supplementing methionine has positive effects on uterine environment, oocyte quality and embryo development in cattle. Thus, the objective of this study was to evaluate reproductive traits of cows…

View details →DOI: 10.1111/rda.13509Cited by 5
Negative / Null Result Report

Plyometrics Did Not Improve Jump-Landing Biomechanics in Individuals With a History of Anterior Cruciate Ligament Reconstruction: A Randomized Controlled Trial

Hyunjae Jeon, Sean Krysak, Steven J. Pfeiffer et al. · 2022 · International Journal of Athletic Therapy and Training

Second anterior cruciate ligament (ACL) injury has similar biomechanical risk factors as primary injury. Standard of care rehabilitation does not adequately mitigate these biomechanical risks. This study examined the effectiveness of a…

View details →DOI: 10.1123/ijatt.2020-0072Cited by 5
Negative / Null Result Report

Union-Find Decoders For Homological Product Codes

Nicolas Delfosse, Matthew B. Hastings · 2021 · Quantum

Homological product codes are a class of codes that can have improved distance while retaining relatively low stabilizer weight. We show how to build union-find decoders for these codes, using a union-find decoder for one of the codes in…

View details →DOI: 10.22331/q-2021-03-10-406Cited by 4
Negative / Null Result Report

“Real‐world” performance of the Confirm Rx™ SharpSense AF detection algorithm: UK Confirm Rx study

Andre Briosa e Gala, Michael T. B. Pope, Milena Leo et al. · 2024 · Journal of Arrhythmia

Abstract Introduction The novel Confirm Rx™ implantable cardiac monitor (ICM) with SharpSense™ technology incorporates a new P‐wave discriminator designed to improve AF detection. This study aimed to evaluate the diagnostic performance of…

View details →DOI: 10.1002/joa3.13124Cited by 4
Negative / Null Result Report

The Addition of the Geriatric Nutritional Risk Index to the Prognostic Scoring Systems Did Not Improve Mortality Prediction in Trauma Patients in the Intensive Care Unit

Cheng-Shyuan Rau, Ching-Hua Tsai, Sheng-En Chou et al. · 2023 · Emergency Medicine International

Background. Malnutrition is prevalent among critically ill patients and has been associated with a poor prognosis. This study sought to determine whether the addition of a nutritional indicator to the various variables of prognostic…

View details →DOI: 10.1155/2023/3768646Cited by 4
Negative / Null Result Report

Fourteen weeks of β-alanine supplementation and HIIT did not improve serum BDNF concentrations and Stroop test performance

Paloma Tavares Mendonça, Yago Medeiros Dutra, Barbara M. Antunes et al. · 2025 · International Journal of Sports Medicine

Abstract This study aimed to investigate whether 14 weeks of β-alanine supplementation and high-intensity intermittent training improves brain-derived neurotrophic factor concentrations and cognitive aspects related to executive functions…

View details →DOI: 10.1055/a-2500-5556Cited by 4
Negative / Null Result Report

Early surgery within 48 hours of admission for hip fracture did not improve 1-year mortality in Japan: a single-institution cohort study

Hiroki Iida, Yasuhiko Takegami, Yoshihito Sakai et al. · 2024 · HIP International

Introduction: Early surgery for hip fracture, within 48 hours of hospital admission, is effective in reducing mortality. However, the average preoperative waiting time for hip fractures in Japan is 4.5 days and the 1-year mortality rate…

View details →DOI: 10.1177/11207000241248836Cited by 4
Negative / Null Result Report

Ovarian damage following surgery for endometriomas, 20 years later: did awareness improve the situation?

Dalila Invernici, Gianfranco Fornelli, Marco Reschini et al. · 2025 · Archives of Gynecology and Obstetrics

Abstract Background Early reports from the beginning of this century highlighted significant ovarian damage following laparoscopic stripping of endometriomas. During the last 2 decades, the raised awareness of the possible detrimental…

View details →DOI: 10.1007/s00404-025-08039-xCited by 4
Negative / Null Result Report

An implementation of Bubble Magnification did not improve the video comprehension of individuals with central vision loss

Francisco M Costela, Stephanie M Reeves, Russell L Woods · 2021 · Ophthalmic and Physiological Optics

Abstract Purpose People with central vision loss (CVL) watch television, videos and movies, but often report difficulty and have reduced video comprehension. An approach to assist viewing videos is electronic magnification of the video…

View details →DOI: 10.1111/opo.12797Cited by 4
Negative / Null Result Report

The adoption of an electronic health record did not improve A1c values in Type 2 diabetes

Harry B Burke, Dorothy A Becher, Albert Hoang et al. · 2016 · Journal of Innovation in Health Informatics

Background: A major justification for the clinical adoption of electronic health records (EHRs) was the expectation that it would improve the quality of medical care. No longitudinal study has tested this assumption.Objective: We used…

View details →DOI: 10.14236/jhi.v23i1.144Cited by 4
Negative / Null Result Report

Improving continuous-flow analysis of triple oxygen isotopes in ice cores: insights from replicate measurements

Lindsey Davidge, Eric J. Steig, Andrew J. Schauer · 2022 · Atmospheric Measurement Techniques

Abstract. Stable water isotope measurements from polar ice cores provide high-resolution information about past hydrologic conditions and are therefore important for understanding earth's climate system. Routine high-resolution…

View details →DOI: 10.5194/amt-15-7337-2022Cited by 4
Negative / Null Result Report

Hydrochar did not reduce rice paddy NH3 volatilization compared to pyrochar in a soil column experiment

Xiaoyu Liu, Yueqin Cheng, Yang Liu et al. · 2020 · Scientific Reports

Abstract Pyrochar (PC) is always with high pH value, and improper application might increase rice paddy ammonia volatilization (PAV), which is the main nitrogen loss through air during rice production. Differently, hydrochar (HC) takes the…

View details →DOI: 10.1038/s41598-020-76213-zCited by 3
Negative / Null Result Report

Virtual Reality-Assisted, Single-Session Exposure for Public Speaking Anxiety: Improved Self-Reports and Heart Rate but No Significant Change in Heart Rate Variability

Tonia-Flery Artemi, Thekla Konstantinou, Stephany Naziri et al. · 2025 · Virtual Worlds

Introduction: This study examines the combined use of objective physiological measures (heart rate [HR], heart rate variability [HRV]) and subjective self-reports to gain a comprehensive understanding of anxiety reduction…

View details →DOI: 10.3390/virtualworlds4020027Cited by 3
Negative / Null Result Report

Addition of an online, validated family history questionnaire to the Dutch FIT-based screening programme did not improve its diagnostic yield

Victorine H. Roos, Frank G. J. Kallenberg, Manon van der Vlugt et al. · 2020 · British Journal of Cancer

Abstract Background Faecal immunochemical testing (FIT) is suboptimal in detecting advanced neoplasia (AN). To increase the sensitivity and yield of a FIT-based screening programme, FIT could be combined with risk factors for AN. We…

View details →DOI: 10.1038/s41416-020-0832-8Cited by 3
Negative / Null Result Report

Did the accuracy of oral amoxicillin dosing of children improve after British National Formulary dose revisions in 2014? National cross-sectional survey in England

Olivia Rann, Mike Sharland, Paul Long et al. · 2017 · BMJ Open

Objectives Inaccurate antibiotic dosing can lead to treatment failure, fuel antimicrobial resistance and increase side effects. The British National Formulary for Children (BNFC) guidance recommends oral antibiotic dosing according to age…

View details →DOI: 10.1136/bmjopen-2017-016363Cited by 3
Negative / Null Result Report

Increased recurrent risk did not improve cerebrovascular disease survivors’ response to stroke in China: a cross-sectional, community-based study

Shengde Li, Li-Ying Cui, Craig Anderson et al. · 2020 · BMC Neurology

Abstract Background Cerebrovascular disease (CVD) survivors are at a high risk of recurrent stroke. Although it is thought that survivors with higher risk of stroke respond better to stroke onset, to date, no study has been able to…

View details →DOI: 10.1186/s12883-020-01724-1Cited by 3
Negative / Null Result Report

Strategically creating maximally heterogeneous lab groups did not improve group performance in an introductory biology lab class

Anisha S. Navlekar, Elli J. Theobald, Ken Griffith et al. · 2025 · PLOS One

Collaboration is a critical skill for professionals in any field to master, and group work is a prominent component of many lab courses. However, there is conflicting guidance about the best method for forming groups to maximize…

View details →DOI: 10.1371/journal.pone.0323799Cited by 3
Negative / Null Result Report

Beaver dam analogs did not improve beaver translocation outcomes in a desert river

Christine Sandbach, Julie K. Young, Mary Conner et al. · 2024 · Restoration Ecology

Stream restoration programs employ beaver‐related restoration techniques, including beaver translocations and installation of beaver dam analogs (BDA), to create complex in‐stream habitat. We investigated whether BDA installations improved…

View details →DOI: 10.1111/rec.14107Cited by 3