A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.
697 results in Negative / Null Result Report for "aging" · page 11 of 24
Bayar E, Cengiz T, Erdoğan F et al. · 2026 · BMC geriatrics
BACKGROUND: Hip fractures represent a major public health concern due to their increasing incidence in the aging population and their association with significant morbidity and mortality. Comorbidities are known to complicate both the…
Schneider BS, Pfaehler CD, Hao KA et al. · 2026 · The Journal of the American Academy of Orthopaedic Surgeons
Background Although os acromiale is often noted on preoperative imaging in patients undergoing reverse total shoulder arthroplasty (rTSA), its clinical significance is ill-defined. The purpose of this study was to compare the clinical…
Jan Tiemann, Matthew McGinity, Ulrik Günther · 2026 · arXiv
In contemporary biology and medicine, 3D microscopy is one of the most widely-used techniques for imaging and manipulation of various kinds of samples. Navigating such a micrometer-sized, 3-dimensional sample under the microscope -- e.g. to find relevant imaging regions -- can pose a tedious challenge for the experimenter. In this paper, we examine whether 2D desktop, 3D desktop, or Virtual Reality (VR) interfaces provide the best user experience and performance for the exploration of 3D samples. We invited 12 skilled microscope operators to perform two different exploration tasks in 2D, 3D an
Karlin NJ · 2026 · Psychological reports
Given the unique challenges faced by frontier aging older adults, such as limited access to healthcare and social services, the potential for different functional disabilities as compared to rural older adults exists. By comparing frontier…
Ozden Sertcelik U, Turker M, Sertcelik A et al. · 2026 · Medicina (Kaunas, Lithuania)
Background and Perspectives : Obstructive sleep apnea (OSA) is a prevalent condition associated with increased perioperative risks. Endobronchial ultrasound (EBUS), a diagnostic and staging procedure requiring deep sedation, may pose…
Vang K, Panich J, Folz C et al. · 2025 · Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners
IntroductionImmune checkpoint inhibitors (CPIs) work by engaging the patient's immune system against tumor cells and have demonstrated a significant benefit in the treatment of cancers. Activation of the patient's immune system can lead to…
Jose A. Rivera, Carmen E. Gonzalez, Tonita Bates · 2024 · JCO Oncology Practice
327 Background: Delayed assessment of diagnostic imaging (DI) significant actionable findings (AFs) at an oncological center prompted the creation of a safety net system which used technological advancements to improve communication…
Ramezani A, Rahimi S, Soltani A et al. · 2026 · Preprint
Abstract Background : Chronic pain is highly prevalent among older adults and has been shown to be associated with differences in cognitive function. While pain intensity reflects the severity of pain, pain interference assesses the extent…
Santos S, Palma-Moreira A, Dias I · 2025 · Preprint
This study aimed to examine the effect of public policies on talent retention in the Portuguese Public Administration and whether the participants' managerial status moderates this relationship. A total of 282 individuals, active workers…
Abassi W, Ouerghi N, Feki O et al. · 2026 · Clinics (Sao Paulo, Brazil)
Objective Obesity is a major independent risk factor for chronic kidney disease. High-Intensity Interval Training (HIIT) is recognized as an interesting therapeutic strategy in managing obesity and related disorders. However, there is…
Dias CS Jr, Verona AP, Leocádio V · 2026 · Journal of religion and health
This study examines the relationship between religious denomination, religious attendance, and mammography screening among White and Black women in Brazil, using baseline data from the Brazilian Longitudinal Study of Aging (ELSI-Brazil,…
Laughlin M, Jack JT, Stephens SE et al. · 2026 · PloS one
Intracardiac flow analysis aims to evaluate blood flow patterns and associated parameters for the assessment of cardiac function. However, there is limited understanding as to how flow parameters are influenced by various sources, such as…
Louis Jalouzot, Alexis Thual, Yair Lakretz et al. · 2025 · arXiv
We investigate optimal strategies for decoding perceived natural speech from fMRI data acquired from a limited number of participants. Leveraging Lebel et al. (2023)'s dataset of 8 participants, we first demonstrate the effectiveness of training deep neural networks to predict LLM-derived text representations from fMRI activity. Then, in this data regime, we observe that multi-subject training does not improve decoding accuracy compared to single-subject approach. Furthermore, training on similar or different stimuli across subjects has a negligible effect on decoding accuracy. Finally, we fin
Li DY, Kim S, Javed S et al. · 2026 · Regional anesthesia and pain medicine
Background Methadone is commonly used as an alternative to other opioids for managing cancer-related pain. High-dose methadone, primarily in opioid dependence treatment, has been associated with QTc prolongation and dangerous arrhythmias.…
Orhan B, Nauta M · 2026 · Death studies
Meaning Management Theory suggests that engaging with meaning-related resources helps individuals constructively regulate consciously experienced death anxiety. Consistent with that theory, we tested whether a single-session, online…
Hamid R, Bayramoğlu MN, Şirolu S et al. · 2026 · Journal of clinical medicine
Background: In this study, we radiologically assessed potential increases in microvascularity, extracellular matrix-related changes, and tissue viscoelasticity following carboxytherapy for periorbital hyperpigmentation (POH). We also…
Hoon OH, Leung SY, Ko TY et al. · 2026 · Cureus
Background and purpose Contrast-enhanced mammography (CEM) has emerged as a valuable imaging modality for breast cancer detection and management. Background parenchymal enhancement (BPE) reflects the level of normal glandular tissue…
Zein MMA, Win KT, Alananzeh I · 2026 · Healthcare informatics research
Objectives This study aims to explore the key factors that enhance engagement in Facebook health support groups among Australian culturally and linguistically diverse (CALD) communities. Methods A cross-sectional online survey was…
Jang M, Kwon S · 2026 · Preprint
Abstract Background The WTO TRIPS flexibilities serve as a health safeguard that protects access to medicines (ATM) by allowing flexibility in pharmaceutical patents. Engaging with state and capital powers, civil society organizations…
Felix Krejca, Tobias Kietreiber, Alexander Buchelt et al. · 2025 · arXiv
The increasing volume of online discussions requires advanced automatic content moderation to maintain responsible discourse. While hate speech detection on social media is well-studied, research on German-language newspaper forums remains limited. Existing studies often neglect platform-specific context, such as user history and article themes. This paper addresses this gap by developing and evaluating binary classification models for automatic content moderation in German newspaper forums, incorporating contextual information. Using LSTM, CNN, and ChatGPT-3.5 Turbo, and leveraging the One Mi
V. Oliveira, R. B. D. Silva, A. Veloso et al. · 2024 · Semina: Ciências Agrárias
The objective of this study was to compare the response of Urochloa decumbens cv. Basilisk pastures in monoculture and silvopastoral systems (SPS), and to determine the most suitable pre-defoliation canopy height for managing this species…
Wang F, Sheng J, Zhang G et al. · 2026 · Health physics
Reducing radiation exposure in pediatric imaging is a key focus globally, and it is necessary to establish diagnostic reference levels (DRLs) for contrast-enhanced computed tomography (CT) in children. This study assesses typical radiation…
Mc Caughey, Gustainis, Ambrosio et al. · 2026 · Ultrasound quarterly
This study evaluates whether contrast-enhanced ultrasound (CEUS) serves as an effective next-step imaging modality for patients with end-stage renal disease (ESRD) who have indeterminate renal lesions on computed tomography (CT), assessing…
Chen Y, Deng M, Xie L et al. · 2026 · Journal of translational medicine
Background The rarity of right heart masses challenges diagnostic proficiency, while reproducibility is affected by the echocardiography operator. Artificial intelligence (AI)-based imaging tools may help address these limitations. Methods…
Weronika Ormaniec, Michael Vollenweider, Elisa Hoskovec · 2025 · arXiv
In this paper, we explore the idea of combining GCNs into one model. To that end, we align the weights of different models layer-wise using optimal transport (OT). We present and evaluate three types of transportation costs and show that the studied fusion method consistently outperforms the performance of vanilla averaging. Finally, we present results suggesting that model fusion using OT is harder in the case of GCNs than MLPs and that incorporating the graph structure into the process does not improve the performance of the method.
Spiegel S, Hübner RH, Schürmann D et al. · 2026 · BMC pulmonary medicine
Background Flexible bronchoscopy is an indispensable tool in respiratory medicine. In the context of an aging society and increasing life expectancy, the number of elderly, often multimorbid patients is growing. This raises important…
Mohamad A. Alanbari, Mohamad A. Alanbari, Hebah M. Hamdan et al. · 2024 · Frontiers in Pediatrics
Background/AimManaging young children with negative behaviors can be challenging in dental settings. Moderate sedation (MS) is often used as a treatment option for such children. However, children's behavior during MS may vary depending on several variables. These variables include parental factors, such as parental anxiety, coping strategies, and pain catastrophizing. However, this area, particularly in Saudi Arabia, remains underexplored. Therefore, this study aimed to assess the association among parental anxiety, coping style, pain catastrophizing, and children's behavior during MS among S
Deng, Zhu, Cao et al. · 2026 · European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society
The clinical evaluation of lumbar degenerative disease (LDD) severity relies on symptoms and imaging, lacking biologically specific diagnostic markers. This study investigated the role of serum complements in LDD to assess their potential…
Chen CD, Aguero C, Melloni A et al. · 2026 · Alzheimer's & dementia : the journal of the Alzheimer's Association
Introduction Alzheimer's disease (AD) biomarkers are assessed on their ability to detect AD pathophysiology in vivo, with confirmation of AD neuropathology only at autopsy. Methods Positron emission tomography (PET), plasma, and cognitive…
Fery Mai Rafanan, Eduard Alfanta, Romulus Roberto Peter Instrella · 2024 · Philippine Journal of Otolaryngology Head and Neck Surgery
Objective: To investigate the association between the time intervals of key clinical time points and tumor progression (increase in clinical staging) in head and neck cancer patients before and during the pandemic. Methods: Design: Retrospective Cohort Study Setting: Tertiary Government Training Hospital Participants: A total of 81 head and neck cancer patients who consulted at the OPD and underwent elective surgery between January 1, 2018, and December 31, 2022, under the Department of Otorhinolaryngology – Head and Neck Surgery of East Avenue Medical Center were included in the study; 40 pat