19,803 real negative results, null findings, and replication failures · Negative / Null Result Report. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Verônica Belchior, Bruno G. Botelho, Adriana S. Franca · 2022 · Foods
The Specialty Coffee Association (SCA) sensory analysis protocol is the methodology that is used to classify specialty coffees. However, because the sensory analysis is sensitive to the taster’s training, cognitive psychology, and…
View details →Natalie L. Wilver, Jesse R. Cougle · 2018 · Journal of Consulting and Clinical Psychology
OBJECTIVE: The current study extended upon previous research efforts by evaluating the utility and feasibility of an 8-session Internet-based interpretation bias modification (IBM) training protocol targeting evaluation- and…
View details →Rune Strand Ødegård, Atle Nesje, Ketil Isaksen et al. · 2017 · The Cryosphere
Abstract. Despite numerous spectacular archaeological discoveries worldwide related to melting ice patches and the emerging field of glacial archaeology, governing processes related to ice patch development during the Holocene and their…
View details →Leon Deutsch, Damjan Osredkar, Janez Plavec et al. · 2021 · Metabolites
Spinal muscular atrophy (SMA) is a genetically heterogeneous group of rare neuromuscular diseases and was until recently the most common genetic cause of death in children. The effects of 2-month nusinersen therapy on urine, serum, and…
View details →Gillian Pepper, Deirdre Corby, Rachel Bamber et al. · 2017 · PeerJ
Here, we report three attempts to replicate a finding from an influential psychological study (Griskevicius et al., 2011b). The original study found interactions between childhood SES and experimental mortality-priming condition in predicting risk acceptance and delay discounting outcomes. The original study used US student samples. We used British university students (replication 1) and British online samples (replications 2 and 3) with a modified version of the original priming material, which was tailored to make it more credible to a British audience. We did not replicate the interaction b
View details →Jan G. Voelkel, Mark J. Brandt, Matteo Colombo · 2018 · Comprehensive Results in Social Psychology
People are prejudiced toward groups they perceive as having a worldview dissimilar from their own. This link between perceived attitudinal dissimilarity and prejudice is so stable that it has been described as a psychological law. The current research tests whether reducing people’s (over-)confidence in their own understanding of policies by puncturing their illusion of explanatory depth in the political domain will reduce the link between perceived attitudinal dissimilarity and prejudice. In an initial pre-registered experiment (N = 296), we did not find support for our hypothesis, but explor
View details →Þórunn Rafnar, Patrick Sulem, Søren Besenbacher et al. · 2011 · Cancer Research
Genome-wide association studies (GWAS) have identified 3 genomic regions, at 15q24-25.1, 5p15.33, and 6p21.33, which associate with the risk of lung cancer. Large meta-analyses of GWA data have failed to find additional associations of…
View details →Huaxin Fan, Hewei Wang, Zhengxu Lian et al. · 2026 · Journal of Stroke
BACKGROUND AND PURPOSE: Therapeutic target selection in noninvasive brain stimulation for poststroke motor recovery typically relies on the interhemispheric inhibition model, which is effective for mildly affected patients but offers…
View details →Shervin Malmasi, Joel Tetreault, Mark Dras · 2015
We examine different ensemble methods, including an oracle, to estimate the upper-limit of classification accuracy for Native Language Identification (NLI). The oracle outperforms state-of-the-art systems by over 10% and results indicate that for many misclassified texts the correct class label receives a significant portion of the ensemble votes, often being the runner-up. We also present a pilot study of human performance for NLI, the first such experiment. While some participants achieve modest results on our simplified setup with 5 L1s, they did not outperform our NLI system, and this perf
View details →Amy Armstrong, Fleur Coburn, Yanyamba Nsereko et al. · 2025 · Journal of Peptide Science
Peptide-drug conjugates (PDCs) are advancing as targeted cancer therapies, leveraging lessons from antibody-drug conjugates (ADCs) to improve tumour specificity. These molecules combine a homing peptide with a cytotoxic payload via a linker, enabling precise drug delivery while sparing healthy tissue. Despite their potential, PDCs face challenges including metabolic instability, premature payload release and rapid clearance, limiting clinical success. Only Lutathera remains FDA-approved after Pepaxto's withdrawal, though Pepaxto retains EMA and MHRA approval-highlighting regulatory and technic
View details →Annelies Spek, Evert Scholte, Ina A. van Berckelaer‐Onnes · 2010 · Journal of Autism and Developmental Disorders
Local information processing in 42 adults with high functioning autism, 41 adults with Asperger syndrome and 41 neurotypical adults was examined. Contrary to our expectations, the disorder groups did not outperform the neurotypical group…
View details →Basil Wahn, Artur Czeszumski, Peter König · 2018 · PLoS ONE
When humans perform tasks together, they may reach a higher performance in comparison to the best member of a group (i.e., a collective benefit). Earlier research showed that interindividual performance similarities predict collective benefits for several joint tasks. Yet, researchers did not test whether this is the case for joint visuospatial tasks. Also, researchers did not investigate whether dyads and triads reach a collective benefit when they are forbidden to exchange any information while performing a visuospatial task. In this study, participants performed a joint visual search task e
View details →Leon Y. Xiao, Tullia C. Fraser, Philip Newall · 2022 · Journal of Gambling Studies
Loot boxes are quasi-gambling virtual products in video games that provide randomised rewards of varying value. Previous studies in Western contexts have identified a positive correlation between loot box purchasing and problem gambling severity. A preregistered survey of People's Republic of China (PRC) video game players (N = 879) failed to replicate this correlation. We observed statistically significant but weak positive correlations between loot box expenditure and past-year gambling participation, and between loot box expenditure and impulsiveness. This study cannot prove that loot boxes
View details →Tamara Beres Lederer Goldberg, Carla Cristiane da Silva, Luciana Peres et al. · 2026 · Archivos Latinoamericanos de Nutrición
Adolescents' eating habits are determined by social, psychological, economic, political, and educational influences. They tend to prefer foods with inadequate nutritional value and high fat and carbohydrate content which leads to excessive…
View details →Masoud Khalili Sabet, Abdorreza Tahriri, Parastou Gholami Pasand · 2013 · Theory and Practice in Language Studies
This paper aimed to examine the impact of peer scaffolding through process approach on writing fluency of EFL learners. To this end, a Nelson Proficiency Test was administered to 49 EFL learners studying at University of Guilan, based on…
View details →Boris Blechacz, Gregory J. Gores · 2010 · Hepatology
A 66-year-old male patient who is hepatitis C RNA–positive without cirrhosis has been found to have a mass on ultrasound examination of the liver. The physical examination is unremarkable. The hemoglobin, white cell count, and platelet…
View details →Elise Boele-Schutte, Ron T. Gansevoort · 2016 · Nephrology Dialysis Transplantation
Because of the circadian rhythm in kidney function the true glomerular filtration rate (GFR) is historically considered to be the average GFR measured by urinary inulin clearance over a 24-h period [1]. In clinical practice, it is…
View details →Jacob Guinot, Sandra Miralles, Alma Rodríguez-Sánchez et al. · 2020 · Employee Relations: The International Journal
Purpose Based on a new management paradigm rooted on care and compassion, this study explores the consequences of compassion at work on organizational learning and firm performance. Design/methodology/approach Structural equation modeling…
View details →Markus Orsi, Jean-Louis Reymond · 2024 · Journal of Cheminformatics
Abstract Molecular fingerprints are indispensable tools in cheminformatics. However, stereochemistry is generally not considered, which is problematic for large molecules which are almost all chiral. Herein we report MAP4C, a chiral…
View details →Jaeseok Bae, Jungjae Park, Heulbi Ahn et al. · 2021 · Optics Express
In this study, an optical method that allows simultaneous thickness measurements of two different layers distributed over a broad thickness range from several tens of nanometers to a few millimeters based on the integration of a…
View details →Frenette Southwood · 2012 · Journal of Child Language
The aims of the study were to establish whether there is a correlation between the socioeconomic background of Afrikaans-speaking children and their performance on a dialect-neutral language test, and to ascertain whether the allowance the…
View details →Ahmad Karimi, Yuna Min, C. Lu et al. · 2012 · Poultry Science
A total of 540 one-day-old male broiler chicks were used to evaluate the potential enhancing effects of a mixture of 2 commercial carbohydrase preparations on phytase efficacy. A nonphytate phosphorus (nPP) deficient diet (0.15%) was…
View details →Albert J. Auguste, Rose M. Langsjoen, Danielle L. Porier et al. · 2021 · Virology
We describe the isolation and characterization of a novel insect-specific flavivirus (ISFV), tentatively named Aripo virus (ARPV), that was isolated from Psorophora albipes mosquitoes collected in Trinidad. The ARPV genome was determined…
View details →Jessica Oi‐Ling Tsang, Jie Zhou, Xiaoyu Zhao et al. · 2021 · Biomedicines
Enteroviruses are important causes of hand, foot, and mouth disease, respiratory infections, and neurological infections in human. A major hurdle for the development of anti-enterovirus agents is the lack of physiologically relevant evaluation platforms that closely correlate with the in vivo state. We established the human small intestinal organoids as a novel platform for characterizing the viral replication kinetics and evaluating candidate antivirals for enteroviruses. The organoids supported productive replication of enterovirus (EV)-A71, coxsackievirus B2, and poliovirus type 3, as evide
View details →Kathryn J. Lester, Susanna Roberts, Robert Keers et al. · 2015 · The British Journal of Psychiatry
BACKGROUND: We previously reported an association between 5HTTLPR genotype and outcome following cognitive-behavioural therapy (CBT) in child anxiety (Cohort 1). Children homozygous for the low-expression short-allele showed more positive…
View details →William L. Baker, Mark A. Williams · 2018 · Ecological Applications
An understanding of how historical fire and structure in dry forests (ponderosa pine, dry mixed conifer) varied across the western United States remains incomplete. Yet, fire strongly affects ecosystem services, and forest restoration…
View details →Shahzad Ahmad, Adelina Orellana, Isabelle Köhler et al. · 2020 · Alzheimer s Research & Therapy
BACKGROUND: Lysophosphatidic acids (LPAs) are bioactive signaling phospholipids that have been implicated in Alzheimer's disease (AD). It is largely unknown whether LPAs are associated with AD pathology and progression from mild cognitive impairment (MCI) to AD. METHODS: The current study was performed on cerebrospinal fluid (CSF) and plasma samples of 182 MCI patients from two independent cohorts. We profiled LPA-derived metabolites using liquid chromatography-mass spectrometry. We evaluated the association of LPAs with CSF biomarkers of AD, Aβ-42, p-tau, and total tau levels overall and stra
View details →Sindu Vivekanandan, Richard Breene, Ramya Ramanujachar et al. · 2015 · Pediatric Blood & Cancer
BACKGROUND: Historically, the 5-year overall survival (OS) for metastatic medulloblastoma (MMB) was less than 40%. The strategy of post-operative induction chemotherapy (IC) followed by hyperfractionated accelerated radiotherapy (HART) and…
View details →Samuel Antwi‐Baffour, Jonathan Kofi Adjei, Peter Owadee Forson et al. · 2019 · Anemia
BACKGROUND: Glucose-6-phosphate dehydrogenase (G6PD) converts glucose-6-phosphate into 6-phosphogluconate in the pentose phosphate pathway and protects red blood cells (RBCs) from oxidative damage. Their deficiency therefore makes RBCs prone to haemolysis. Sickle cell disease (SCD) on the other hand is a hereditary blood disorder in which there is a single nucleotide substitution in the codon for amino acid 6 substituting glutamic acid with valine. SCD patients are prone to haemolysis due to the shape of their red blood cells and if they are deficient in G6PD, the haemolysis may escalate. Repo
View details →Recep A. Ozdemir, Sofia Kirkman, Justine R. Magnuson et al. · 2022 · Neuroimage Reports
Prior studies have suggested that oscillatory activity in cortical networks can modulate stimulus-evoked responses through time-varying fluctuations in neural excitation-inhibition dynamics. Studies combining transcranial magnetic…
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