Negative / Null Result ReportOpen accessMedicine (General)
Salla Atkins, Tiia Reho, Nina Talola et al. · 2020 · Trials
Abstract Background Prolonging working careers is a key policy goal in ageing populations in Europe, but reaching this goal is complex. Occupational health services are in the best position to contribute towards prolonging working careers through preventing illnesses that cause work disability and early retirement. However, impacting on the trajectory between illness and work disability requires continuity of care and follow up, enabled through identifying patients at risk. We aimed to determine whether a combined educational and electronic reminder system in occupational health care could imp
View details →Negative / Null Result ReportOpen accessTherapeutics. Pharmacology
Shaheen Akhtar, Sanjeev Verma, Navinder Pal Singh et al. · 2023 · National Journal of Physiology, Pharmacy and Pharmacology
Background: With improvement in living conditions in the population and the availability of treatments for various communicable and non-communicable diseases, the life expectancy and consequently the elderly population have increased. Stress leads to mental and physical problems. Aim and Objective: The aim of this study was to assess the effect of stress on muscle functions in the elderly. Materials and Methods: One hundred apparently healthy persons (50 males and 50 females) took part in the study. Perceived stress scale was used to measure their level of stress. Maximum voluntary contraction
View details →Negative / Null Result ReportOpen accessMedicine
Wejpisit Wongwiwattananon, Jatuporn Pakpirom, Raviwan Akarapatima · 2020 · Journal of Health Science and Medical Research (JHSMR)
Objective: This study aimed to determine the risks of propofol-based total intravenous anesthesia (TIVA) compared to local anesthesia (LA) in patients undergoing percutaneous transluminal angioplasty (PTA) in a lower extremity. Material and Methods: A retrospective cohort study was conducted in 231 patients who underwent PTA in the lower extremity using either propofol-based TIVA or LA between January 2016 and September 2018. The outcomes of interest included perioperative major adverse cardiac events (MACE) and minor perioperative complications. Risk factors analysis was performed using a uni
View details →Negative / Null Result ReportOpen accessEnglish language
Masoome Azmoode Sis Abad, Gholam-Reza Kiany, Gholam-Reza Abassian · 2024 · Journal of Modern Research in English Language Studies
The present research responds to the call for implementing diagnostic assessment through learner involvement. This study followed two aims: first, examining the distinctive effects of diagnostic self- and peer - assessments on EFL learners’ reading comprehension; second, exploring students’ diagnostic rating accuracy in various reading genres. To achieve this, a number of diagnostic reading comprehension tests and a checklist were developed, the construction of which were based on the learners’ challenging reading subskills. The participants include 60 English translation university students.
View details →Negative / Null Result ReportOpen accessPublic aspects of medicine
Ahmed M. Aman Allah, Waad M. Malibarey, Sarah S. Bin Baz et al. · 2025 · The Saudi Journal of Health Systems Research
Introduction: Telehealth is a potential method for improving the quality of care for people diagnosed with type 2 diabetes (T2D). In Saudi Arabia, there is limited research on the effectiveness of telehealth for glycemic control compared to usual care. Thus, the aim of the current study was to determine the impact of telehealth on glycemic control in individuals diagnosed with T2D, with a specific focus on the examination of hemoglobin A1c (HbA1c) values. Methods: A retrospective case-control cohort study was conducted between January and August 2024 on people diagnosed with T2D who were manag
View details →Negative / Null Result ReportOpen accessSports medicine
Mario Hevesi MD, PhD, Alexander M. Boos, Allen Wang et al. · 2024 · Orthopaedic Journal of Sports Medicine
Objectives: Medial meniscus posterior root tears (MMPRTs) render the meniscus essentially non-functional, resulting in increased peak contact pressures, reduced forced dissipation, and increased risk of early osteoarthritis. Transtibial root repair has shown promise at restoring meniscus function and improving clinical outcomes; however, a paucity of literature exists evaluating the prognostic clinical and radiographic factors for poor outcomes following isolated meniscus root repair. The purpose of this study was to 1) describe the patient reported clinical outcomes after isolated MMPRT repai
View details →Negative / Null Result ReportOpen accessMedicine
Matthias Huber, Till Treutler, Peter Martus et al. · 2013 · PLoS ONE
Unlabelled Treatment of hypertension in hemodialysis (HD) patients is characterised by lack of evidence for both the blood pressure (BP) target goal and the recommended drug class to use. Telmisartan, an Angiotensin receptor blocker (ARB) that is metabolised in the liver and not excreted via HD extracorporeal circuit might be particularly suitable for HD patients. We designed and conducted a randomised, placebo-controlled, double-blind and cross-over trial for treatment of dialysis-associated hypertension with telmisartan 80 mg once daily or placebo on top of standard antihypertensive treatmen
View details →Negative / Null Result ReportOpen accessOrthopedic surgery
Taeko Fukuda, Shinobu Imai, Shunji Simoda et al. · 2020 · Journal of Orthopaedic Surgery
Purpose: It is unclear whether perioperative analgesic techniques affect the functional outcome of total knee replacement (TKR). We investigated the effects of peripheral nerve block (PNB) and local infiltration (LI) on walking ability after TKR. Methods: The medical records of 7143 patients who underwent TKR using general anesthesia with PNB or LI techniques were reviewed. Factors affecting independence and/or improvement of walking after surgery were investigated using multivariate regression analysis. To adjust for baseline differences and minimize selection bias for the chosen analgesic te
View details →Negative / Null Result ReportOpen accessMedicine
Thaiz Ferraz Borin, Debora A P C Zuccari, Bruna V Jardim-Perassi et al. · 2014 · PLoS ONE
A selective inhibitor of 20-HETE synthesis, HET0016, has been reported to inhibit angiogenesis. 20-HETE has been known as a second mitogenic messenger of angiogenesis inducing growth factors. HET0016 effects were analyzed on MDA-MB-231 derived breast cancer in mouse and in vitro cell line. MDA-MB-231 tumor cells were implanted in animals' right flank and randomly assigned to early (1 and 2), starting treatments on day 0, or delayed groups (3 and 4) on day 8 after implantation of tumor. Animals received HET0016 (10 mg/kg) treatment via intraperitoneal injection for 5 days/week for either 3 or 4
View details →Negative / Null Result ReportOpen accessAgriculture
Ana Guiomar Matos Santiago Reis, Raquel Yvonne Arantes Baccarin · 2010 · Ciência Rural
Twenty Thoroughbred racehorses were ultrasonographically evaluated to determine the relation between normal values of the cross-sectional area (CSA) of the right and left forelimbs superficial digital flexor tendons (SDFT) in the metacarpal region for trained and untrained Thoroughbreds racehorses. Ultrasonography revealed that CSA at 26cm distal to the accessory carpal bone is larger than other proximal levels, for either left or right forelimbs. In addition, the CSA at 2, 4, 6, 8, 10, 12 and 14cm distal to the accessory carpal bone of the left forelimb are larger (P 0.05) between left and ri
View details →Negative / Null Result ReportOpen accessSurgery
Yoshihiro Sakai, Shunsuke Kasai, Akio Shiomi et al. · 2026 · Annals of Gastroenterological Surgery
ABSTRACT Aim Few reports have described pelvic reinforcement procedure (PRP) to prevent perineal hernia (PH) in robotic abdominoperineal resection (Ro‐APR) for rectal cancer. This study aimed to investigate the safety and efficacy of PRP in Ro‐APR. Methods Patients who underwent Ro‐APR for rectal cancer between January 2020 and June 2023 were retrospectively examined. PRP was performed as a prophylactic procedure for PH. Four types of PRP were performed depending on the case (closure of the levator ani muscles, the pelvic peritoneum with the uterus, the pelvic peritoneum, and the pelvic perito
View details →Negative / Null Result ReportOpen accessMedicine (General)
Thuy Thi-Thanh Tran, Huy Phuong Tran, Loc Thai Ly et al. · 2024 · Middle East Fertility Society Journal
Abstract Background Endometrial preparation significantly influences the success of embryo transfer procedures. Although both oral and transdermal estradiol are common methods for endometrial priming, their efficacy and potential side effects remain uncertain. This randomized controlled trial aims to compare the effectiveness of oral and transdermal estradiol in endometrial preparation, while also evaluating their respective side effects in patients undergoing assisted reproduction treatments. Method This randomized clinical trial (ISRCTN15301227) was conducted at Hung Vuong Hospital between J
View details →Negative / Null Result ReportOpen accessMedicine
Elham Naghshineh, Safoura Rouholamin, Zahra Derakhshandeh · 2023 · Advanced Biomedical Research
Background: Asherman syndrome is a controversial issue in obstetrics and gynecology without any consensus on its management and treatment. It is characterized by variable lesions inside the uterine cavity and also causes menstrual irregularities, infertility, and placental abnormalities. The study aimed to assess the platelet-rich plasma (PRP) effect in women with intrauterine adhesions by evaluating the improvement of the menstrual cycle and intrauterine adhesion (IUA) stage. Materials and Methods: This clinical trial study was performed on 60 women with Asherman syndrome in two groups of 30.
View details →Negative / Null Result ReportOpen access
Wynands, Seth · 2015
This paper examines the socio-political instability link between inequality and investment. For the period between 1960 and 2011 for 192 countries, this paper finds no significant correlation between inequality and instability and no…
View details →Negative / Null Result ReportOpen access
Mismetti, Patrick, Decousus, Hervé, Moulin, Nathalie et al. · 2006
International audienceIn a prospective study, nine patients with phlegmasia caerulea dolens (PCD) related to iliac occlusive thrombosis were treated with intravenous thrombolysis. After thrombolysis, despite no significant improvement in…
View details →Negative / Null Result ReportOpen access
Seung Whan Doo (703584), Young Myoung Ko (703588), Hwa Yeon Sun (3628463) et al. · 2017
Total IPSS and Qmax showed no significant improvement. Storage IPSS and QoL showed significant improvement and PVR showed significant increase. The black diamond signifies that the mean difference is in favor of IPSS. The size of each…
View details →Negative / Null Result ReportOpen access
J. R. Mondt, D. C. Siegla · 1974
Heat transfer and flow friction behavior have been measured for plain and perforated plate-fin and 10-deg herringbone surfaces. For the range of geometries and Reynolds numbers studied, the perforations produced no significant improvement…
View details →Negative / Null Result ReportOpen access
Akerley, Wallace, Herndon, James E. 2nd, Vokes, Everett E. et al. · 2017
BACKGROUND: In Cancer and Leukemia Group B 39801, we evaluated whether induction chemotherapy before concurrent chemoradiotherapy would result in improved survival and demonstrated no significant benefit from the addition of induction…
View details →Negative / Null Result ReportOpen access
Akerley, Wallace, Vokes, Everett E., Cicchetti, M Giulia et al. · 2009
BackgroundIn Cancer and Leukemia Group B 39801, we evaluated whether induction chemotherapy before concurrent chemoradiotherapy would result in improved survival and demonstrated no significant benefit from the addition of induction…
View details →Negative / Null Result ReportOpen access
Jiankang Jin (703171), Stephen J. Archibald (703175), Janani Panneerselvam (703170) et al. · 2015
A , RT-PCR analysis showed IL-24 reduced CXCR4 mRNA levels at 6 h and 24 h ( P B , CXCR4 promoter activity was determined using a luciferase reporter vector. Induction of IL-24 showed no significant reduction in luciferase activity…
View details →Negative / Null Result ReportOpen access
Andrew W. Taylor (451751) · 2013
The macrophages lysates were assayed for protein concentration and Caspase 3 activity. There was no significant change of Caspase 3 activity in cells treated with α-MSH compared to SFM cells. The graft is the mean ± SD of Caspase 3…
View details →Negative / Null Result ReportOpen access
Sandra Demaria (15026216), Shannon Martello (11246282), Molykutty J. Aryankalayil (5544962) et al. · 2020
Metabolic data from PC3 cells 6h, 24h, and 48h after SD or MF radiation. Samples were sent to Metabolon for processing. Results indicate decrease in glycolysis intermediates in SD sample at 6h. No significant changes to TCA cycle…
View details →Negative / Null Result ReportOpen access
Hull, Glenn · 2017
This paper determines the effects of police interventions on darknet markets. Darknet markets have been rapidly growing and the amount of drugs being sold on them keeps rising. This paper finds no significant changes in prices of drug…
View details →Negative / Null Result ReportOpen access
Tristan G. Pesaresi (6751925), Grayson Breneman Ashby (6751931), Min-Ken Liao (6751934) et al. · 2019
Working memory correct (A), working memory incorrect (B) and reference memory (C) errors over the 12 days of testing are shown between low fat and high fat-fed rats. There were no significant differences between dietary group for any of…
View details →Negative / Null Result ReportOpen access
Christopher D. Green, Gladys M. Batten, Anton F. De Man et al. · 1983
Three studies examined Adler's suggestion that firstborns are past-oriented. The first study of the relationship between birthorder and temporal relatedness and dominance in 37 female undergraduates yielded no significant differences. The…
View details →Negative / Null Result ReportOpen access
Ronald L. Halberg, Michael A. Nelson · 1979
Threshold contrasts for red, green, and achromatic sinusoidal gratings were measured. Spatial frequencies ranged from 0.25 to 15 cycles/deg. No significant differences in contrast thresholds were found among the three grating types. From…
View details →Negative / Null Result ReportOpen access
Ayako Asakura (711890), Takahisa Goto (711892), Takahiro Mihara (789554) · 2015
No significant differences were detected among the groups, but the maximum decreases tended to be smaller in the CHO and ORS groups than in the control group. B. Box plot of the final temperature changes at the end of surgery. No…
View details →Negative / Null Result ReportOpen access
Manolis AS, Padeletti L., Mont L et al. · 2008
Dual-chamber (DDD) pacing has generally been regarded as "physiologic pacing" and therefore expected to be superior to ventricular pacing. Major randomized trials have so far failed to demonstrate significant reductions in the incidences…
View details →Negative / Null Result ReportOpen access
José M. Ferro, Guilhermina Cantinho, Élia Baeta · 1991
A 45-year-old right-handed man developed “crossed” anomie aphasia, neglect and inaccurate reaching of his left arm in both hemispaces due to a right parietal haemorrhage. Aphasia cleared in a few days. SPECT failed to demonstrate crossed…
View details →Negative / Null Result ReportOpen access
Manuel Carlos Martins Castro (5255606) · 2022
ABSTRACT Online hemodiafiltration is potentially a superior mode of dialysis compared to conventional hemodialysis. However, prospective randomized controlled trials have failed to demonstrate such superiority. Post-hoc analyses of these…
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