19,923 real negative results, null findings, and replication failures · Negative / Null Result Report. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Chen Y, Bhatti P, Dummer T et al. · 2025 · Cancer epidemiology
Background Studies of the relationship between diabetes medications and pancreatic cancer risk have produced inconclusive results. We aimed to examine associations between classes, subclasses, and individual diabetes medications with…
View details →Baldini GM, Ferri D, Lot D et al. · 2026 · Gynecologic and obstetric investigation
Objectives The objective of the study was to evaluate the impact of male human papillomavirus (HPV) sexually transmitted infection on sperm parameters, embryo morphokinetics, and clinical pregnancy outcomes in assisted reproductive…
View details →Sunman B, Yalcin E, Alboga D et al. · 2025 · Pediatric allergy, immunology, and pulmonology
Background: Although the forced oscillation technique has been used for many years in children, there is still inconclusive results about its efficiency in cystic fibrosis (CF). Moreover, no studies have been conducted on impulse…
View details →He S, Wen J, Zou Z et al. · 2025 · International journal of cancer
Studies on multiple myeloma (MM), the second most common hematologic malignancy, have shown inconclusive results regarding the role of exercise in treatment. This study evaluated the relationship between physical exercise and MM treatment…
View details →Pierucci UM, Paraboschi I, Ardenghi C et al. · 2024 · Translational pediatrics
Background Inflammatory myofibroblastic tumors (IMTs) are rare, often non-metastasizing neoplasms characterized by fibro/myofibroblastic spindle cells with varying infiltrates of plasma cells, lymphocytes, and/or eosinophils. Despite their…
View details →Rohrhofer J, Ebner L, Schweighardt J et al. · 2025 · Diagnostics (Basel, Switzerland)
Background/Objectives: Growing evidence suggests that mast cell activation (MCA) may contribute to Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS), a debilitating disorder characterized by persistent fatigue and post-exertional…
View details →Suksard K, Millard GM, Teravichitchainan U et al. · 2025 · Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis
Background ABO discrepancies, inconclusive results between forward and reverse typing, are one of the significant challenges encountered in transfusion medicine. Their frequency and etiologies can vary among ethnicities. This study aimed…
View details →Hashem S, Murhega RB, Migabo PA · 2026 · Radiology case reports
The ectopic posterior pituitary represents a rare congenital malformation attributable to aberrant embryogenesis of the neurohypophysis. Although it may occur as an isolated anomaly, it is frequently concomitant with other congenital…
View details →de Oliveira Castro Marques TR, Vidal SA, da Costa HA et al. · 2026 · Hematology, transfusion and cell therapy
Background Stroke, the most severe neurological complication of sickle cell disease, can result in irreversible sequelae and death. Transcranial Doppler combined with periodic blood transfusions reduces the chances of stroke by 90 %. In…
View details →Tu Y, Miao J, Wu Q et al. · 2025 · Respiratory medicine
Background Previous epidemiological studies have explored the association between obstructive sleep apnea (OSA) and osteoporosis (OP), with inconclusive results due to various biases. Herein, we sought to determine the causal association…
View details →Guarneri C, Reschini M, Pinna M et al. · 2024 · Journal of assisted reproduction and genetics
Purpose To evaluate whether a second biopsy, following a first diagnostic failure on blastocysts tested for preimplantation genetic testing for monogenic diseases (PGT-M), allows to obtain genetic diagnosis and to what extent this…
View details →Mehta SP, Antonio Aguirre B, See WYN et al. · 2025 · Preprint
Purpose Whole exome or genome sequencing (WES and WGS, respectively) can be valuable in identifying the molecular basis of inherited retinal disorders (IRD), particularly when panel-based testing yields negative or inconclusive results.…
View details →Su XY, Schroder A, Tse LA et al. · 2025 · BMC research notes
Background Sex hormones may play a role in the development of nasopharyngeal carcinoma (NPC), but the evidence is limited. Methods This case-control study collected information on sex hormonal and reproductive factors of 99 female incident…
View details →Khorram A · 2024 · Preprint
Abstract Introduction: To date, studies exploring shockwave-assisted orthodontic tooth movement and tooth mobility have produced inconclusive results, largely attributable to varying methodologies and a lack of standardized reporting. This…
View details →Rosa ML, Bordignon C, Schuch JB et al. · 2026 · Diagnostics (Basel, Switzerland)
Background/Objectives : Formalin-fixed paraffin-embedded tissue is widely used in pathology and molecular diagnostics, yet its variable quality can critically influence the accuracy of sequencing-based analyses. This study investigated…
View details →Gopalaswamy R, Kumar N, Vashistha H et al. · 2023 · Frontiers in public health
Introduction Truenat MTB-RIF assay (Truenat), a nucleic acid amplification test (NAAT), is a real-time polymerase chain reaction (RT-PCR) chip-based assay that can detect Mycobacterium tuberculosis ( Mtb ) and rifampicin (RIF) drug…
View details →Tavelli R, Callens M, Grootaert C et al. · 2024 · Trends in Food Science & Technology.
Microplastics (MPs) contaminate the global marine and terrestrial ecosystems. This environmental contamination can enter the food chain, with MPs found in drinking water, fishery products and other food categories. Consequently, ingestion…
View details →Nohales M, Coello A, Martin A et al. · 2023 · Journal of assisted reproduction and genetics
Purpose To investigate whether embryo rebiopsy increases the yield of in vitro fertilization (IVF) cycles. Methods Retrospective study including 18,028 blastocysts submitted for trophectoderm biopsy and preimplantation genetic testing for…
View details →Cummings M, Madhavan S · 2024 · Experimental brain research
Ischemic Conditioning (IC) is a procedure involving brief periods of occlusion followed by reperfusion in stationary limbs. Blood Flow Restriction with Exercise (BFR-E) is a technique comprising blood flow restriction during aerobic or…
View details →Salgotra M, Bharti N, Sinha V et al. · 2024 · Journal of pharmacy & bioallied sciences
Introduction Although PCOS affects reproductive health, its consequences on the outcome of pregnancies are still up for discussion. Comparing the pregnancy outcomes of women with PCOS to a control group was the goal of this retrospective…
View details →Linthorst J, Nivard M, Sistermans EA · 2024 · Cell reports
The properties of cell-free DNA (cfDNA) are intensely studied for their potential as non-invasive biomarkers. We explored the effect of common genetic variants on the concentration and fragmentation properties of cfDNA using a genome-wide…
View details →Pham YT, Nguyen BN, Nguyen TG et al. · 2026 · Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
Background Iron is one of the essential elements for human life. Prior studies provided inconclusive results about the association between dietary iron intake and gastric cancer risk. We determined the association between dietary iron…
View details →Santiago-Torner C · 2024 · Preprint
Creativity in virtual work environments and its influence on emotional exhaustion is a relationship with inconclusive results. Furthermore, autonomy, when it loses its original purpose of acting as a job resource, takes on an ambiguous…
View details →Pardi C, Hellberg Å, Isakson P · 2024 · Blood transfusion = Trasfusione del sangue
Background The Rh blood group system is highly complex, polymorphic, and immunogenic. The presence of RHD gene variants in RhD negative pregnant women is a challenge in fetal RHD genotyping as it may influence the antenatal management of…
View details →Boyarchuk O, Volianska L, Smashna O et al. · 2024 · Frontiers in genetics
Introduction Developmental delay (DD) in children is often caused by genetic abnormalities, which are challenging to diagnose due to the vast genetic variability. Methods This study presents a detailed analysis of whole-exome sequencing…
View details →Gutowska A, Bohdan M, Radtke-Łysek A et al. · 2026 · The American journal of case reports
BACKGROUND Cardiac myxomas are the most common primary cardiac tumors in the general population but are exceedingly rare in orthotopic heart transplant recipients. Fewer than 5 cases have been reported. Their pathogenesis in the setting of…
View details →Mattke S, Jun H, Hanson M et al. · 2024 · The journal of prevention of Alzheimer's disease
Introduction As treatments for secondary prevention of Alzheimer's disease (AD) are being studied, concerns about their value for money have appeared. We estimate cost-effectiveness of a hypothetical screening and prevention program.…
View details →Harjunen L, Östman K, Pohl P · 2025 · Disability and rehabilitation
Purpose Ronnie Gardiner Method (RGM) is a music-based movement therapy that has long been used within rehabilitation. There is a need to (1) identify the scope of the use of RGM, (2) explore potential benefits, (3) examine qualitative…
View details →Portillo-Gallo JH, Sánchez-González JM, Saldaña-Cruz AM et al. · 2026 · Current issues in molecular biology
Pre-eclampsia is a Hypertensive Disorder of Pregnancy (HDP) characterized by hypertension and proteinuria, affecting 2-8% of pregnancies worldwide and constituting a major public health concern. Genes of the renin-angiotensin system have…
View details →Beissat K, Lattard V, Picard-Meyer E et al. · 2025 · PloS one
Since the beginning of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic, a wide range of animal species (pets, mink…) have been naturally infected with this betacoronavirus. The emergence of new variants has…
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