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20,261 real negative results, null findings, and replication failures · Negative / Null Result Report. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result ReportMedicine

ESR1 as a candidate gene for adolescent idiopathic scoliosis pathogenesis in North-West Indian population.

Kowra S, Singh H, Singh V et al. · 2026 · European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society

Introduction Estrogens are crucial in the development and growth of skeletal systems. Estrogen receptor alpha (ESRα) and beta (ESRβ) are crucial regulators of estrogen response. Estrogen receptor genes (ESR1 and ESR2) have been extensively…

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Negative / Null Result ReportMedicine

Association Between Selenium, Ferritin, and Haemoglobin Levels and the Development of Preeclampsia.

Taymur BD, Toklucu G, Gunkaya OS et al. · 2026 · Journal of the College of Physicians and Surgeons--Pakistan : JCPSP

Objective To evaluate the association between Selenium (Se) and other micronutrients (iron, ferritin, copper, zinc, and vitamin B12) and the development of preeclampsia (PE), and to assess their predictive performance. Study design An…

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Negative / Null Result ReportMedicine

Episodic migraine is associated with a more atherogenic lipid profile rather than independent insulin resistance: a case-control study.

Szabóová S, Duraníková O, Örzsik B et al. · 2026 · Lipids in health and disease

Background Cardiometabolic factors may influence migraine biology through metabolic, inflammatory, and vascular mechanisms, but studies examining insulin resistance and dyslipidaemia in migraine have yielded inconsistent results, partly…

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Negative / Null Result ReportMedicine

Physical Activity Patterns and Kidney Function Changes Among Hispanic/Latino Adults: The Hispanic Community Health Study/Study of Latinos.

Rivas-Nieto AC, Alver SK, Mooney SJ et al. · 2026 · Journal of physical activity & health

Background Physical activity (PA) may be a modifiable factor for chronic kidney disease (CKD) prevention, but evidence specific to Hispanic/Latino populations is limited. Our objective was to examine associations between PA type/volume…

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Negative / Null Result ReportMedicine

Retrospectively reported childhood ADHD symptoms and addiction severity in emerging adults with substance use disorders: cross-sectional indirect associations through time perspective.

Demirci SC, Aşik UB, Menkü BE et al. · 2026 · BMC psychiatry

Background Symptoms of attention-deficit/hyperactivity disorder (ADHD) are commonly observed in individuals with substance use disorders (SUD) and may be associated with increased addiction severity. Time perspective is a potential…

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Negative / Null Result ReportMedicine

Relationship Between Standing Long Jump Performance and Health-Related Indicators and Lifestyle Factors in Chilean Adolescents: A Cross-Sectional Study.

Montalva-Valenzuela F, Guzmán-Muñoz E, Castillo-Paredes A et al. · 2026 · Healthcare (Basel, Switzerland)

Background: The standing long jump (SLJ) is a field-based test of lower-limb muscular fitness in youth and a proposed indicator of health-related physical fitness. However, evidence on its relationship with psychological, sleep, dietary,…

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Negative / Null Result ReportMedicine

Perinatal and Lifestyle Factors Associated with Childhood Alanine Aminotransferase Levels as an Early Indicator of Metabolic Dysfunction-Associated Steatotic Liver Disease: A Population-Based Study.

de Ruyter H, Aitokari L, Iqbal A et al. · 2026 · The Journal of pediatrics

Objective To investigate associations of perinatal and lifestyle factors with alanine aminotransferase (ALT) levels as an early indicator of metabolic dysfunction-associated steatotic liver disease (MASLD). Study design Data from the…

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Negative / Null Result ReportMedicine

Systemic inflammatory indices as predictors of adverse outcomes in pregnancies with vascular events: A retrospective cohort study.

Toptas GR, Firatligil FB, Ozdal BB et al. · 2026 · International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics

Objective To investigate the association between systemic inflammatory indices, including the systemic immune-inflammation index (SII), systemic inflammation response index (SIRI), and aggregate index of systemic inflammation (AISI), and…

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Negative / Null Result ReportMedicine

The relationship between pre-incarceration related social determinants and glycaemic control in African Americans with criminal legal involvement and type 2 diabetes.

Akinboboye O, Walker RJ, Campbell JA et al. · 2026 · Diabetic medicine : a journal of the British Diabetic Association

Aims To evaluate the relationship between pre-incarceration social determinants, demographic and clinical factors, and glycaemic control in African Americans with a history of criminal legal involvement and type 2 diabetes mellitus.…

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Negative / Null Result ReportMedicine

Surgical Helmet Systems Were Not Associated With Lower Operative Infection Rates After Total Ankle Arthroplasty: A Retrospective Cohort Study.

McCahon JAS, Thomas GM, Hsu A et al. · 2026 · Foot & ankle international

BackgroundConflicting evidence exists regarding the ability of surgical helmet systems (SHSs) to reduce rates of infection after joint replacement. The purpose of this study was to investigate the use of SHS in total ankle arthroplasty…

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Negative / Null Result ReportOpen accessMedicine

Subcutaneous Tranexamic Acid Achieves Comparable Serum Concentrations to Intramuscular Administration During Haemorrhagic Shock in a Swine Model.

Lynghaug T, Fuskevåg OM, Storm BS et al. · 2026 · Acta anaesthesiologica Scandinavica

Background Tranexamic acid is an antifibrinolytic agent reducing mortality when administered to trauma patients with haemorrhagic shock. This mortality reduction is time sensitive. Increased intramuscular dose administration has proven an…

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