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Browse the failure-mode index

19,923 real negative results, null findings, and replication failures · Negative / Null Result Report. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result Report

Association between global longitudinal strain and coronary artery calcium in the diagnosis of significant coronary artery disease

M Shvydka, M Lutay, I Golikova · 2026 · European Heart Journal - Cardiovascular Imaging

Abstract Introduction Non-invasive diagnostic methods for coronary artery disease (CAD) are gaining increasing importance due to their accessibility, diagnostic value, safety, and cost-effectiveness. Both global longitudinal strain (GLS)…

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Negative / Null Result Report

The Association between a Recorded Diagnosis of Obesity and Clinically Significant Weight Loss in the Primary Care Setting: A Nationwide Registry

Michal Kasher Meron, Nira Koren-Morag, Dan Oieru · 2024 · Obesity Facts

Introduction: Overweight and obesity (OW/OB) are underdiagnosed. The primary aim was to assess whether a diagnosis of OW/OB recorded by a primary care physician (PCP) is associated with clinically significant weight loss, compared to a…

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Negative / Null Result Report

A Study on the Job Training Support Experience of Job Coach for the Vocational Rehabilitation Support Project for the People with a Significant Disability

Min-Sik Kim, Young-Ran Kim · 2024 · The K Association of Education Research

This study focuses on experience of Job Coach in Occupational Rehabilitation Support Projects that is offered by the field at the Field-Centric Occupational Rehabilitation Centers. The purpose of the study is to present better support to…

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Negative / Null Result Report

Abstract 4364710: Association Between Pre-Operative History of Significant Bleeding and Post-Operative Cardiovascular Events Following Lower Extremity Revascularization

David Bresnahan, Yuhe Xia, Elliot Luttrell-Williams et al. · 2025 · Circulation

Background and Hypothesis: Patients with symptomatic peripheral artery disease (PAD) frequently undergo lower extremity revascularization (LER) but remain at increased risk of major adverse cardiovascular and limb events following the…

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Negative / Null Result Report

Is There a Significant Association Between Body Image and Psychological Health in Moroccan Postmenopausal Women? A Cross-Sectional Study

Sara Esseffar, Said Bellahcen, Ghizlane Azizi et al. · 2025 · The Open Public Health Journal

Background Menopause and its consequences, sometimes complex, can generate discomfort in well-being and consequently affect the quality of women’s lives. Objective The present study was carried out to examine the quality of life of…

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Negative / Null Result Report

LACK OF SIGNIFICANT ASSOCIATION BETWEEN COMPONENT ALIGNMENT AND FUNCTIONAL OUTCOME IN TOTAL HIP ARTHROPLASTY

Ismail Hadisoebroto Dilogo, Wildan Latief, Muh Trimugroho Fahrudhin · 2018 · Journal of Southeast Asian Medical Research

Background : Total hip replacement (THR) failure isinfluenced bythe prosthesis component orientation. The debate is still ongoing to determine the best angles for acetabular or femoral components. Objective :To evaluate the functional…

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Negative / Null Result Report

No significant association between 40bp ins/del promoter polymorphism of MDM2 and breast cancer susceptibility in Pakistani women

Sania Gull, Nabeela Tariq, Hamida Ali et al. · 2025 · LIAQUAT MEDICAL RESEARCH JOURNAL

Breast cancer remains the most prevalent malignancy among women, and is the second leading cause of mortality worldwide. Genetic heterogeneity in the MDM2 promoter region has been associated with increased cancer susceptibility. The study…

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Negative / Null Result Report

Non-invasive right ventricular myocardial work in patients with significant tricuspid regurgitation: association with etiology and outcome

Y Obayashi, S C Butcher, X Galloo et al. · 2026 · European Heart Journal - Cardiovascular Imaging

Abstract Background/Introduction Right ventricular (RV) function is a key factor in risk stratification of patients with tricuspid regurgitation (TR). Right ventricular myocardial work (RVMW) has been proposed as a novel echocardiographic…

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Negative / Null Result Report

No significant association between quadriceps tendon alignment and 1‐year patient‐reported outcomes following physiological total knee arthroplasty without patellar resurfacing

Manabu Akagawa, Roberto Berebichez‐Fridman, Loic Villet et al. · 2026 · Knee Surgery, Sports Traumatology, Arthroscopy

Abstract Purpose This study aimed to clarify the clinical relevance of quadriceps tendon alignment (QTA), focusing on the quadriceps tendon axial angle (QTAx), in patients undergoing ‘physiological total knee arthroplasty (TKA)’. This…

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Negative / Null Result Report

Association between postdischarge antibiotic use and C. difficile testing as a surrogate for clinically significant diarrhea

Daniel J. Livorsi, James Merchant, Hyunkeun Cho et al. · 2025 · Antimicrobial Stewardship & Healthcare Epidemiology

Abstract Objective: Postdischarge antibiotics are often sub-optimal or unnecessary. This study sought to measure the risk of diarrhea in recently hospitalized patients treated with postdischarge antibiotics Design: Retrospective cohort…

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Negative / Null Result Report

A174 TESTING FOR AND INCIDENCE OF CELIAC DISEASE AUTOIMMUNITY SAW SIGNIFICANT BUT TEMPORARY DECLINES DURING COVID-19 PANDEMIC

J A King, S Coward, G G Kaplan et al. · 2024 · Journal of the Canadian Association of Gastroenterology

Abstract Background Celiac disease (CD) is an autoimmune disorder with various complications and long-term health risks. The COVID-19 pandemic affected the entire healthcare system—including screening for and diagnosing non-infectious…

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Negative / Null Result Report

Association of postsystolic shortening on stress echocardiography and significant coronary artery stenosis: A single‐centre retrospective cohort study

Joel Toftgård, Henrik Hedskog, Lars Rune et al. · 2024 · Clinical Physiology and Functional Imaging

Abstract Background Postsystolic shortening (PSS) is one of the proposed quantitative measures to predict myocardial ischaemia in the stress echocardiographic (SE) evaluation. It is previously known that hypo‐/akinesia (HA) correlates well…

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Negative / Null Result Report

Association of TSH Levels in the Therapeutically Neglected Range of 6.5–8 mIU/L with Significant Changes in Liver and Kidney Function: A Retrospective Study of the Kashmiri Population

Tousief Ahmed, Ruqaya Aziz · 2022 · Sudan Journal of Medical Sciences

Background: The thyroid gland secretes hormones crucial for growth, differentiation, regulation of metabolic processes, and homeostasis. In response to underactivity of this gland, the pituitary secretes thyrotropin, also known as the…

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Negative / Null Result Report

Lack of Significant Association between Stromal Tumor-Infiltrating Lymphocytes (TILs) and 2014 FIGO Stage in Epithelial Ovarian Cancer: A Cross-Sectional Study

Amanda Putri, Aswiyanti Asri, Puja Agung Antonius · 2026 · JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga

Highlights: Understanding the relationship between TIL infiltration and tumor stage could refine prognostic models and guide targeted therapies. Tumor-infiltrating lymphocytes density is considered an essential immune marker in ovarian…

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Negative / Null Result Report

Heparinized venous blood gas syringes are associated with a significant decrease in measured packed cell volume in dogs due to hemodilution

Coyne M. Hopey, Dana Caldwell, Erin Binagia et al. · 2025 · Journal of the American Veterinary Medical Association

Abstract OBJECTIVE To assess the effect of hemodilution on PCV when commercial preheparinized venous blood gas (PH-VBG) syringes are used compared to directly filled Hct tubes, and to evaluate the impact of delayed centrifugation on PCV.…

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Negative / Null Result Report

Allergies, asthma treatment, and eviction diet have a significant impact on the respiratory effort during sleep and the apnea-hypopnea index in children with obstructive sleep apnea-obesity/asthma association: A STROBE-compliant study

Kalomoira Kefala, Philippe Guerin · 2026 · Medicine

The pathophysiological mechanisms implicated in obstructive sleep apnea (OSA) associated with asthma/allergies remain unclear. Apnea-hypopnea index (AHI) alone is insufficient to accurately guide adequate treatment without identifying the…

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Negative / Null Result Report

Cyber defence automation: Can AI outperform hackers?

Vitalii Yasenenko · 2025 · Technologies and Engineering

Growing cyber threats in the context of digital transformation require improved methods of automating cyber defence, in particular, through the use of artificial intelligence to detect and respond to attacks. The purpose of the study was…

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Negative / Null Result Report

Can Artificial Intelligence Outperform Humans in ETF Management?

Sahana Ganesan · 2024 · Journal of Student Research

‘Exchange Traded Funds’ (ETFs) are basket/bundle funds consisting of a portfolio of stock assets from multiple companies and organizations, traded similar to normal stocks. ETFs help with diversification of the investment, risk management…

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