Negative / Null Result ReportOpen accessMedicine
Zhao Jiandong, Yuan Yongyi, Chen Jing et al. · 2012 · Journal of Translational Medicine
Abstract Background Many patients with enlarged vestibular aqueduct (EVA) have either only one allelic mutant of the SLC26A4 gene or lack any detectable mutation. In this study, multiplex ligation-dependent probe amplification (MLPA) was used to screen for copy number variations (CNVs) of SLC26A4 and to reveal the pathogenic mechanisms of non-syndromic EVA (NSEVA). Methods Between January 2003 and March 2010, 923 Chinese patients (481 males, 442 females) with NSEVA were recruited. Among these, 68 patients (7.4%) were found to carry only one mutant allele of SLC26A4 and 39 patients (4.2%) lacke
View details →Negative / Null Result ReportOpen accessDiseases of the circulatory (Cardiovascular) system
Takumi Osawa, Hitoshi Mori, Akane Kawai et al. · 2022 · Journal of Arrhythmia
Abstract Background Uninterrupted dabigatran during atrial fibrillation (AF) ablation is now established as the standard therapy. However, there are few reports on the effects of uninterrupted dabigatran on the intensity of anticoagulation during AF ablation. Methods We retrospectively analyzed 247 consecutive patients who underwent AF ablation in our hospital from January 2017 to December 2018. Patients who took warfarin or uninterrupted direct oral anticoagulants (DOACs) except for dabigatran were excluded. 89 patients underwent ablation with uninterrupted dabigatran (uninterrupted group, ma
View details →Negative / Null Result ReportOpen accessDentistry
Hamed Kalhor, Mamak Adel, Maryam Tofangchiha et al. · 2026 · Annali di Stomatologia
Objectives: This study aimed to assess the effect of a metal artifact removal (MAR) algorithm on the visibility of the second mesiobuccal canal (MB2) of maxillary molars on cone-beam computed tomography (CBCT) scans. Materials and Methods: This cross-sectional study evaluated 41 CBCT scans of patients retrieved from the radiology clinic’s archives. The CBCT scans were saved with and without the MAR algorithm applied. The images were coded and evaluated by two endodontists to assess MB2 detection in maxillary molars and its visibility level using a 5-point Likert scale. Of the 164 samples, 32 w
View details →Negative / Null Result ReportOpen accessInternal medicine
LI Wen-hong, WANG Jin-wen, CHEN Hao et al. · 2015 · Linchuang shenzangbing zazhi
Objective To study the clinical curative effectiveness of high frequency ultrafiltration for the renal edema with diuretic resistance.Methods We selected 42 cases of nephrotic syndrome with severe edema.Among them,there were 20 cases of diabetic kidney disease,10 cases of lupus nephritis,8 cases of refractory primary nephrotic syndrome,and 4 cases of multiple myeloma nephropathy.All patients were subjected to standard treatment for 3-5 days according to different primary diseases after admission.Their urine was less than 800 mL every day and it met the standard of diuretic resistance.Then the
View details →Negative / Null Result ReportOpen accessNeurosciences. Biological psychiatry. Neuropsychiatry
Alsubaie SS · 2025 · Neuropsychiatric Disease and Treatment
Sultan Saad Alsubaie Department of Psychiatry, Armed Forces Hospital, Khamis Mushayt, Saudi ArabiaCorrespondence: Sultan Saad Alsubaie, Consultant Psychiatrist, psychiatry department, Armed Forces Hospital Southern Region, P.O. Box 101, Khamis Mushayt, Saudi Arabia, Tel +96-6503799971, Email dr.slt4444@gmail.comPurpose: This study aims to compare self-esteem and social anxiety disorder (SAD) symptoms levels between visually impaired and sighted individuals, and to explore the relationship between social anxiety and various sociodemographic factors.Materials and Methods: A case-control study wa
View details →Negative / Null Result ReportOpen accessAnimal culture
P. P. Singh, Ashok Kumar, R. S. Chauhan et al. · 2016 · Veterinary World
Aim: The present study was aimed to investigate the immunological competence of chlorpyrifos (CPF) insecticide after oral administration in layer chickens. Materials and Methods: A total of 20 White Leghorn birds were given CPF in drinking water at 0.3 ppm/bird/day (no observable effect level dose) for a period of 3-month. Immune competence status of layer birds and chicks hatched from CPF-treated birds were estimated at 15 days interval in layer birds and monthly interval in chicks using immunological and biochemical parameters. Results: There was a significant decrease in values of total leu
View details →Negative / Null Result ReportOpen accessSurgery
Ahmet Adnan Cırık, Yeşim Esen Yiğit, Ahmet Mahmut Tekin et al. · 2024 · Frontiers in Surgery
PurposeThis study aimed to assess the readability indices of websites including educational materials on otosclerosis.MethodsWe performed a Google search on 19 April 2023 using the term “otosclerosis.” The first 50 hits were collected and analyzed. The websites were categorized into two groups: websites for health professionals and general websites for patients. Readability indices were calculated using the website https://www.webfx.com/tools/read-able/.ResultsA total of 33 websites were eligible and analyzed (20 health professional-oriented and 13 patient-oriented websites). When patient-orie
View details →Negative / Null Result ReportOpen accessMedicine
Justin Fulkerson, MSN, Robert Lowe, BSN, Tristan Anderson, BSN et al. · 2016 · Western Journal of Emergency Medicine
Introduction: This study compared the effects of vasopressin via tibial intraosseous (IO) and intravenous (IV) routes on maximum plasma concentration (Cmax), the time to maximum concentration (Tmax), return of spontaneous circulation (ROSC), and time to ROSC in a hypovolemic cardiac arrest model. Methods: This study was a randomized prospective, between-subjects experimental design. A computer program randomly assigned 28 Yorkshire swine to one of four groups: IV (n=7), IO tibia (n=7), cardiopulmonary resuscitation (CPR) + defibrillation (n=7), and a control group that received just CPR (n=7).
View details →Negative / Null Result ReportOpen accessMedicine (General)
Zhen Yu Jia, Yuan Yuan Jiang, Jung Min Woo et al. · 2018 · Neurointervention
Purpose Wide-neck aneurysms (WNAs) associated with a dilated parent artery (PA) are not uncommon morphological abnormalities and usually cause inappropriate wall apposition and incomplete neck coverage of a tubular stent in stent-assisted coiling of aneurysms. We aimed to introduce a fusiform-shaped stent (FSS) and test its effectiveness in treating intracranial WNAs associated with a dilated PA using a three-dimensional (3D) model. Materials and Methods Two FSS types were designed with the middle one-third segment dilated by 10% (FSS10) and 20% (FSS20) and were compared with the tubular-shape
View details →Negative / Null Result ReportOpen accessPublic aspects of medicine
Said Kara · 2022 · Journal of Public Health in Africa
Background. The purpose of this study was to investigate the connection between self-efficacy and treatment adherence, working on the assumption that self-efficacy plays a role in determining treatment adherence in chronic diseases. Hypertension affects one-third of the world’s population. In Africa, hypertension is a leading cause of death from a non-communicable disease. Modifications to lifestyle and behavior, as well as increased access to pharmaceuticals, are necessary for every African nation to bring the prevalence of hypertension and cardiovascular disorders under control. Methods. In
View details →Negative / Null Result ReportOpen accessNuclear engineering. Atomic power
Junhyuk Jang, Minsoo Lee, Gha-Young Kim et al. · 2025 · Nuclear Engineering and Technology
Copper oxidation at low temperatures below 140 °C and its effects on corrosive behavior in aerobic groundwater are investigated to estimate the intactness of canisters at early stages of disposal. The Cu coupon surface is covered by fine particles that form thin oxide layers after 30 d of oxidation; a thin Cu2O layer of thickness <100 nm is formed after oxidation at 40 °C; after oxidation at 140 °C, the Cu2O surface changes to a CuO layer of thickness <500 nm. The thickness of the Cu surface oxidized at 90 °C is between those of the surfaces oxidized at 40 and 140 °C. All Cu coupons exhibit si
View details →Negative / Null Result ReportOpen accessMedicine
Zainab Y. Ejam, Şevki Adem, Asmaa Kadhim Gatea · 2024 · Medical Journal of Babylon
Background: Vascular endothelial growth factor (VEGF) is crucial for the implantation of a fertilized egg and for the development of placental blood vessels. This study was conducted to detect the serum VEGF level of pregnant with different types of assisted reproductive techniques in relation to the age group, body mass index (BMI), and type of infertility. Objectives: The aim of this study was to determine the levels of serum VEGF in different types of assisted pregnancy. Materials and Methods: Enzyme-linked immunosorbent assay was used for the detection of VEGF levels in the serum of pregna
View details →Negative / Null Result ReportOpen accessSports medicine
Iraj Hoseinzade, Ahmad Abdi, Asieh Abbassi Daloii · 2022 · فیزیولوژی ورزش و فعالیت بدنی
Background and Purpose: Fat tissue, frequently the largest organ in humans, is at the nexus of mechanisms involved in longevity and age-related metabolic dysfunction. Fat distribution and function change dramatically throughout life. Obesity is a major risk factor for development of comorbidities such as type-2 diabetes, neurological disorders, osteoarthritis, cancer, cardiovascular and renal diseases, which is associated with increased senescent cell and heart disorders. Exercise training and natural supplements constitute an indispensable, tool in the management of obesity and obesity-relate
View details →Negative / Null Result ReportOpen accessBiotechnology
Tomáš Svoboda, Daniel Ruman, Milan Gaff et al. · 2015 · BioResources
The influence of selected factors, such as wood species, veneer combinations, and loading cycles, on the bending strength and modulus of elasticity of glued laminated wood was investigated after cyclic loading of 0, 1000, 3000, and 7000 cycles with European beech (Fagus sylvatica (L.)) and Eurasian aspen (Populus tremula (L.)) The laminated woods were created by a combination of densified and non-densified veneers. The 30% densification was carried out by cold rolling. All factors and their interactions had statistically significant influence on the modulus of elasticity. Similarly, the influe
View details →Negative / Null Result ReportOpen accessVeterinary medicine
Tytti Maaria Niemelä, Riitta-Mari Tulamo, Jorge Uriel Carmona et al. · 2019 · Acta Veterinaria Scandinavica
Abstract Background Inflammatory and degenerative activity inside the joint can be studied in vivo by analysis of synovial fluid biomarkers. In addition to pro-inflammatory mediators, several anabolic and anti-inflammatory substances are produced during the disease process. They counteract the catabolic effects of the pro-inflammatory cytokines and thus diminish the cartilage damage. The response of synovial fluid biomarkers after intra-articular hyaluronan injection, alone or in combination with other substances, has been examined only in a few equine studies. The effects of hyaluronan on som
View details →Negative / Null Result ReportOpen accessPharmacy and materia medica
Saeid Abbasi-Maleki, Hadi Yousefi*, Rahim Sharafkhani et al. · 2023 · Research Journal of Pharmacognosy
Background and objectives: Earlier researches have exhibited the antioxidant, antinociceptive, and antiepileptic effects of Ferula gummosa. Considering that antioxidants play a key role in the pathogenesis of depression, the antidepressant potential of the F. gummosa essential oil was assessed by using a mouse models. Methods:Lorke’s method was used to access the acute toxicity of the F. gummosa essential oil. The F. gummosa essential oil (5-40 mg/kg), standard agents, and vehicle were administered to animals. The forced-swimming test (FST), tail suspension test (TST), and open-field test (OFT
View details →Negative / Null Result ReportOpen accessNeurology. Diseases of the nervous system
Bilge Kocer, Hayat Guven, Isik Conkbayir et al. · 2016 · Parkinson's Disease
Factors related with hyperhomocysteinemia (HHcy) and the impact of HHcy in Parkinson’s disease (PD) are not well understood. We investigated the factors associated with increased levels of homocysteine (Hcy) and the relationship between HHcy and motor symptoms, cognitive status, and vascular risk in patients with Parkinson’s disease. Among 60 patients (29 males, 48.3%) with PD, the stage of the disease, the severity of clinical symptoms, and the patients’ cognitive status were measured using a modified Hoehn and Yahr Staging Scale (mHY), Unified Parkinson’s Disease Rating Scale (UPDRS) II and
View details →Negative / Null Result ReportOpen accessPsychology
Huan Chen, Luyao Wang, Shaogui Xu et al. · 2022 · Behavioral Sciences
The outbreak of COVID-19 has brought increasing attention to proximity travel. This mode of travel is a convenient travel setup for both tourists and neighboring destinations. With the help of the model of goal-directed behavior (MGB), this study investigates the influence of tourists’ perception of epidemic risk on their intentions for proximity travel during the normalization of epidemic prevention and control. This study takes Shenzhen, China as the research area, and carried out the investigation in the context of normalization of the epidemic in China. A total of 489 pieces of valid sampl
View details →Negative / Null Result ReportOpen accessSports medicine
Xianfu Song, Dan Wang, Dexin Wang et al. · 2026 · BMC Sports Science, Medicine and Rehabilitation
Abstract Objective This study investigated the effects of an 8-week Taekwondo program on the attention of children aged 7–8 years, exploring its potential as a motor intervention during a critical developmental period. Methods Forty children were randomly assigned to either an experimental group (EG, n = 20), which participated in a structured Taekwondo program (three 45-minute sessions/week at ≥ 60% HRmax), or a control group (CG, n = 20), which attended regular physical education classes. Attention was assessed pre- and post-intervention using tasks measuring stability, allocation, shifting,
View details →Negative / Null Result ReportOpen accessMedicine
Pius Pum Tseuguem, Télesphore Benoît Nguelefack, Elvine Pami Nguelefack-Mbuyo et al. · 2026 · Scientific Reports
Abstract Extracts of Paullinia pinnata have demonstrated therapeutic effects in monosodium urate (MSU)-induced gout in rats, notably by reducing inflammation and hyperalgesia, as well as enhancing antioxidant activity in vivo. However, their in vitro antioxidant potential and their effects on MSU-stimulated macrophages remain insufficiently explored. This study aims to investigate the in vitro antioxidant properties of P. pinnata, with a particular focus on MSU uptake in stimulated macrophages. The in vitro antioxidant activities of aqueous (AEPP) and methanolic (MEPP) extracts of P. pinnata l
View details →Negative / Null Result ReportOpen accessAccounting. Bookkeeping
Teguh Erawati, Nur Ghailina As’ari · 2018 · Akuntansi Dewantara
This study aims to determine the effect of understanding tax laws, service quality, taxpayer awareness, and tax sanctions on taxpayer compliance of individuals at the District Rongkop, district Gunungkidul. This research type is quantitative research by using primary data. The population in this study is all taxpayers of individuals registered in KPP Pratama Wonosari. and the criteria of respondents in the study are registered Private Taxpayers. Data analysis in this research using multiple regression with SPSS program version 16.0. The results showed that the value of F arithmetic 27.707 grea
View details →Negative / Null Result ReportOpen accessMedicine
Yuchun Liu, Ning Wang, Changsong Jiang et al. · 2020 · Scientific Reports
Abstract Among surface irrigation systems, long border and furrow are more adaptive to mechanized farming but may cause a non-uniform distribution of water and nutrients. In this study, field experiments were carried out in a flat silage corn field in Hebei, China to investigate the uniformity along the length of border or furrow to understand the spatial and temporal distribution characteristics of soil water, electrical conductivity, and nitrate. This will guide irrigation and fertigation management recommendations, land consolidation, and high standard farmland construction. Border and furr
View details →Negative / Null Result ReportOpen accessPsychiatry
Meret Sophie Wallimann, Katharina Beck, David Cyrill Lätsch · 2026 · European Journal of Psychotraumatology
Background: Psychological maltreatment is linked to negative developmental outcomes in adolescents. It includes psychological abuse (PA) and psychological neglect (PN), which are commonly studied as a pair. This study applied the dimensional model of adversity and psychopathology (DMAP), which conceptualises abuse as a threatening experience involving harm or the threat of harm that primarily impairs social-emotional processing, such as emotion regulation, while it views neglect as deprivation or absence of parental care that predominantly affects cognitive functioning, such as working memory.
View details →Negative / Null Result ReportOpen accessNeurosciences. Biological psychiatry. Neuropsychiatry
Fabian Timm, Esther Kuehn, Esther Kuehn et al. · 2020 · Frontiers in Human Neuroscience
Repetitive sensory stimulation of the fingertip induces Hebbian plasticity in the sensorimotor cortex that benefits the tactile and motor behavior of the hand in healthy younger adults, older adults, and patients. To use this method outside the laboratory, robust and portable stimulation systems are needed that allow prolonged stimulation phases over several hours without compromising on signal intensity or personal mobility. Here, we introduce two stimulation gloves that apply finger- and frequency-specific mechanical stimulation to individual fingertips over prolonged periods. The stimulator
View details →Negative / Null Result ReportOpen accessEcology
Alexandra Kinnby, Ricardo T. Pereyra, Jonathan N. Havenhand et al. · 2019 · BMC Ecology
Abstract Background In the brackish Baltic Sea, shedding of adventitious branches is central to asexual recruitment of new thalli in the brown algae Fucus vesiculosus and F. radicans. To test which factors influence the formation of adventitious branches in brackish and in more marine conditions, we sampled 29 Fucus sites in the Baltic Sea (salinity 3–11) and 18 sites from the Danish straits, Kattegat, Skagerrak, and the North Sea (salinity 15–35). Separately for each area, we used structural equation modelling to determine which of eight predictor factors (phosphate, nitrate, chlorophyll-a (a
View details →Negative / Null Result ReportOpen accessBusiness
Bambang Sugeng Dwiyanto · 2012 · Jurnal Maksipreneur: Manajemen, Koperasi, dan Entrepreneurship
Bankcruptcy is a very important problem, in which every company should be aware of. It is very important to detect the signs of the coming bankruptcy of the company as soon as possible in order to take effective action to avoid it. One popular model to do so is Z-score, a statistical model to predict bankruptcy based on company financial performance. This paper deals with the analysis of the financial performance of property companies listed on the Indonesia Stock Exchange. However, in previous research it was found that there is no strong correlation between the companies financial performanc
View details →Negative / Null Result ReportOpen accessMedicine
Bing-Hui Li, Tong Deng, Qiao Huang et al. · 2019 · American Journal of Men's Health
The objective of this study was to evaluate association between body mass index (BMI) and prostate volume (PV), international prostate symptom scores (IPSS), maximum urinary flow rate ( Q max ), and post-void residual (PVR) of Chinese benign prostatic hyperplasia (BPH) patients. All newly diagnosed BPH patients between September 2016 and August 2018 were selected and 788 patients were included. According to BMI, the patients were categorized into four groups, while according to PV, IPSS, Q max , and PVR, they were categorized into two groups based on clinical significant cutoffs. Univariable a
View details →Negative / Null Result ReportOpen accessInfectious and parasitic diseases
Knowles Donald P, Ueti Massaro W, Bastos Reginaldo G et al. · 2010 · Parasites & Vectors
Abstract Background Rhipicephalus ( Boophilus ) microplus is an economically important tick of cattle involved in the transmission of Babesia bovis , the etiological agent of bovine babesiosis. Commercial anti-tick vaccines based on the R. microplus Bm86 glycoprotein have shown some effect in controlling tick infestation; however their efficacy as a stand-alone solution for tick control has been questioned. Understanding the role of the Bm86 gene product in tick biology is critical to identifying additional methods to utilize Bm86 to reduce R. microplus infestation and babesia transmission. Ad
View details →Negative / Null Result ReportOpen accessTechnology
Awham Jumah Salman, Zahraa Fakhri Jawad, Rusul Jaber Ghayyib et al. · 2022 · Energies
Silica is considered one of the most prevalent components in the Earth’s shell and is synthesized for use in technological applications. Nevertheless, new methods for finding a better, cheaper, and more ecologically friendly supply of silica with less energy consumption are unavoidable. This study investigates whether nanopowders made from waste with a great silica amount (fly ash and glass) can be utilized as fillers in an epoxy glue to enhance its characteristics. Four different contents (5, 10, 15, and 20 wt%) of nano–fly ash, nanoglass, and nanosilica powder were introduced into the sample
View details →Negative / Null Result ReportOpen accessAgriculture (General)
Quentin Struelens, Diego Mina, Olivier Dangles · 2021 · CABI Agriculture and Bioscience
Abstract Background Landscape composition has the potential to foster regulating ecosystem services such as pollination and biocontrol in temperate regions. However, most landscape studies do not take pesticide use into account even though it is the main control strategy worldwide and has negative impacts on beneficial insects. Moreover, few studies have explored these combined effects in smallholder cropping system with diverse landscapes and small cultivated fields. Methods We assessed the effect of semi-natural cover and pesticide use on pollinator and herbivore abundances and functions in
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