Negative / Null Result ReportMedicine
van Amstel, Simons, Kooreman et al. · 2026 · Breast (Edinburgh, Scotland)
In clinically node-positive (cN+) patients, radioactive iodine ( 125 I) seeds can be considered to mark metastatic axillary lymph nodes before neoadjuvant therapy (MARI-procedure) but potential therapeutic effects remain unclear. This…
View details →Negative / Null Result ReportMedicine
Shen, Yan, Yan et al. · 2026 · Journal of environmental sciences (China)
Diazotrophs play a crucial role within the rhizosphere by fixing atmospheric nitrogen and promoting plant growth. However, the diversity of diazotrophic communities and the influences of human activity are largely unclear. This study…
View details →Negative / Null Result ReportMedicine
Uludag, Uludag · 2026 · Current medicinal chemistry
Recently, there has been growing interest in the roles of vitamin D and certain platelet characteristics, such as mean platelet volume (MPV). However, the influence of vitamin D levels on these platelet traits is still under discussion.…
View details →Negative / Null Result ReportMedicine
Estaji, Ahmadizadeh · 2026 · Journal of psychiatric research
Based on neurocognitive models, the development and maintenance of post-traumatic stress disorder (PTSD) are correlated with cognitive biases, including attention and memory biases, which are associated with imbalanced activation of…
View details →Negative / Null Result ReportMedicine
Cazalis-Henry, Seuront, Spilmont · 2026 · Biology letters
Brown macroalgae like Fucus serratus are key ecosystem engineers in intertidal environments and are increasingly threatened by anthropogenic pollution and global change. This study examined how the combined effects of conventional and…
View details →Negative / Null Result ReportMedicine
Grub, Naab · 2026 · Digital health
To examine user perceptions of human advisors versus chatbots in mental health apps and assess the impact of algorithm literacy interventions. In an online experiment, participants engaged in simulated chats about digital stress. A…
View details →Negative / Null Result ReportMedicine
Maureen, Budiardjo, Wahono · 2026 · Journal of the Indian Society of Pedodontics and Preventive Dentistry
Down syndrome is a genetic condition caused by trisomy 21, often accompanied by orofacial hypotonia and anomalies in stomatognathic development. A hypotonic tongue may alter oral cavity morphology, particularly palatal depth, anterior…
View details →Negative / Null Result ReportMedicine
Goh, Sud, Chau et al. · 2026 · Medicina (Kaunas, Lithuania)
Background and Objectives : Renin-angiotensin system inhibitors (RASIs) are recommended to preserve residual kidney function (RKF) in patients on peritoneal dialysis (PD); however, evidence of benefit is inconsistent. This study evaluated…
View details →Negative / Null Result ReportMedicine
Ptáček, Musil, Guarnieri et al. · 2026 · International journal of molecular sciences
Amyotrophic lateral sclerosis (ALS) is a common neurodegenerative disorder; to date, there is no long-term effective treatment. Recently, a relationship has been discovered between the human intestinal microbiome and the pathogenesis of…
View details →Negative / Null Result ReportMedicine
Deng, Xiang, Li et al. · 2026 · Animals : an open access journal from MDPI
Due to the lack of corn and soybean meal in animal feeding, rice bran meal (RBM) has been proposed as a beneficial substitute for these feedstocks' ingredients. Its fermentation by using diverse microbes has been adopted as a beneficial…
View details →Negative / Null Result ReportMedicine
Hazell, Khazova, O'Mahoney · 2026 · Antioxidants (Basel, Switzerland)
Conflicting evidence exists on whether blue or red light modulates nitric oxide (NO) release within skin cells. Using environmentally relevant doses, irradiances and spectral distribution akin to low-level sunlight, we provide evidence…
View details →Negative / Null Result ReportMedicine
Tas, Erturk · 2026 · Indian journal of surgical oncology
Due to controversial results, the clinical impact of sex in pancreatic cancer has not been fully clarified. We aimed to investigate the clinical significance of sex in patients with pancreatic cancer in this study. A total of 334…
View details →Negative / Null Result ReportMedicine
Expósito-Díaz, Medina, Moral · 2026 · Environmental microbiology reports
Olive anthracnose, the most critical disease affecting fruit and oil quality, is caused by Colletotrichum species, with C. godetiae dominant in Italian and Spanish orchards. Climate change could exacerbate its impact, particularly through…
View details →Negative / Null Result ReportMedicine
Pujol, Minguell, Pijoan et al. · 2025 · Journal of orthopaedics
To determine if maintaining the preoperative CPAK class influences on clinical outcomes when performing a functional aligned robotic assisted TKA (RATKA). This prospective cohort study compared patients who maintained their preoperative…
View details →Negative / Null Result ReportMedicine
Zhou, Lu, Wang et al. · 2026 · PeerJ
The clinical impact of sperm chromatin condensation defects (SCCD) on in vitro fertilization (IVF) outcomes remains controversial. This study aimed to clarify the effects of SCCD on embryonic development, pregnancy, and neonatal outcomes…
View details →Negative / Null Result ReportMedicine
Ergün, Bayraktar Nahir · 2026 · Odontology
Pit and fissure sealants (PFS) are effective in preventing occlusal caries. This randomized split-mouth clinical study aimed to compare the 18-month clinical performance of the bioactive resin-based PFS (BioCoat™) with a…
View details →Negative / Null Result ReportMedicine
Fan, Luo, Zheng et al. · 2026 · Physiology & behavior
The circadian clock genes Per1 and Per2 play a crucial role in regulating circadian rhythms. However, the consequences of their deficiency on motor function and age-related behavioral changes remain poorly understood. This study aimed to…
View details →Negative / Null Result ReportMedicine
Fojcik, Górski, Szulik et al. · 2025 · Frontiers in psychiatry
The aim of this study was to determine the risk of suicidal behavior in patients who were involuntarily hospitalized in forensic psychiatry departments, taking into account demographic variables such as age, level of education and length…
View details →Negative / Null Result ReportMedicine
Schmidt, Brühl, Möllers et al. · 2026 · Haemophilia : the official journal of the World Federation of Hemophilia
Sufficient sleep is essential for maintaining both physical and mental health, yet data on sleep health among persons with haemophilia (PwH) remain limited. This study aimed to assess sleep in PwH compared to healthy controls (Con) and…
View details →Negative / Null Result ReportMedicine
Bregen, de Buhr, Strutzberg-Minder et al. · 2026 · Veterinary sciences
The reasons for disease outbreaks caused by Actinobacillus pleuropneumoniae (APP) in vaccinated pigs are often unknown and remain a challenge for farmers and veterinarians. One hypothesis for APP vaccine failure is the timing of APP…
View details →Negative / Null Result ReportMedicine
Wang, Ouyang, Chen et al. · 2026 · Scientific reports
This study aims to explore the impact of wearing Defocus Incorporated Multiple Segments (DIMS) spectacle lenses on astigmatism in myopic children. This study included 396 myopic children and divided the participants into two groups:the…
View details →Negative / Null Result ReportMedicine
Ma, Qiu, Liu · 2025 · Frontiers in nutrition
Acute-on-chronic liver failure (ACLF) patients face high risks of nutritional risk and clinical complications, but whether adjuvant nutritional support reduces adverse complications remains unclear. This study included 6,097 hospitalized…
View details →Negative / Null Result ReportMedicine
Kır · 2026 · PeerJ
This research compares the yield and quality of barley ( Hordeum vulgare ), rye ( Secale cereale ), triticale (× Triticosecale Wittmack ), and wheat ( Triticum aestivum ) grown in dry conditions in winter and widely used in producing…
View details →Negative / Null Result ReportMedicine
Cheng, Wang, Liu et al. · 2026 · PloS one
There has been ongoing debate over whether people are intuitively honest or intuitively dishonest. A recent social harm account was proposed to address this debate: dishonesty is intuitive when cheating inflicts harm on an abstract other…
View details →Negative / Null Result ReportMedicine
Li, Wang, Shen et al. · 2026 · International journal of cancer
Gastric carcinoma (GC) with neuroendocrine differentiation (GCNED) is a rare and particular pathological subtype. The survival outcomes and prognosis of patients with GCNED are currently unclear. We conducted a retrospective cohort study…
View details →Negative / Null Result ReportMedicine
Pires Marafon, Reuter, Isola et al. · 2026 · Transfusion clinique et biologique : journal de la Societe francaise de transfusion sanguine
The legal shelf life of platelet concentrates (PCs) has been extended from 5 to 7 days in France since 2018. Our study aimed to determine whether this increase in PC storage time has produced a significant impact on…
View details →Negative / Null Result ReportMedicine
Akkaya, Kosar · 2026 · Journal of endodontics
To investigate the influence of different types of intracanal medicaments and root canal sealers on root dentine fracture resistance at different time intervals. A total of 180 single-rooted human mandibular premolars were used. Samples…
View details →Negative / Null Result ReportMedicine
Liu, Zhang, Yuan et al. · 2026 · Chemical science
Hexafluoropropylene oxide-dimer acid (HFPO-DA) is widely used in food packaging bags, surfactants, lubricants, etc. As a new substitute for the persistent organic pollutant perfluorooctanoic acid (PFOA), it has been proven to have…
View details →Negative / Null Result ReportOpen accessOcean engineering
Jiaxing Xin, Ying Cui, Jun Yang et al. · 2025 · IEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing
The intensification of the urban heat island (UHI) effect poses a serious threat to public health, particularly in cities. Effectively mitigating UHI has been a focus of national and international academic research over the last decades. However, most contemporary research has focused on land use mitigation measures within urban areas, with less emphasis on suburban land use. To address this research gap and explore spatial characteristics, we analyzed the driving mechanism of suburban land use patterns on UHI intensity (UHII) within the main urban area of Shenyang City based on high spatial r
View details →Negative / Null Result ReportOpen accessNeoplasms. Tumors. Oncology. Including cancer and carcinogens
Bilan Yang, Xiaoli Xi, Hongsheng Yu et al. · 2024 · Cancer Reports
Abstract Background The optimal treatment strategy for early‐stage hepatocellular carcinoma (HCC) remains controversial, specifically in regard to surgical resection (SR) and ablation. The aim of this study was to investigate the impact of SR and ablation on recurrence and prognosis in early‐stage HCC patients, to optimize treatment strategies and improve long‐term survival. Methods A retrospective analysis was conducted on 801 patients diagnosed with Barcelona Clinic Liver Cancer (BCLC) stage 0/A HCC and treated with SR or ablation between January 2015 and December 2019. The effectiveness and
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