e-ISSN: Pending

Browse the failure-mode index

20,261 real negative results, null findings, and replication failures · Negative / Null Result Report. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result ReportOpen accessMedicine

Ocular Findings in Women with Cervical HPV Positivity and Cervical Dysplasia Undergoing Loop Electrosurgical Excision Procedure: A Prospective Cross-Sectional Study.

Vural NA, Mergen B, Güler S et al. · 2026 · Medicina (Kaunas, Lithuania)

Background and Objectives : To evaluate ocular findings in women with cervical HPV positivity undergoing loop electrosurgical excision procedure (LEEP) for cervical dysplasia and to assess conjunctival/eyelid papilloma and other ocular…

View details →
Negative / Null Result ReportMedicine

Impact of preoperative use of biologics on 30-day surgical morbidity and mortality in patients with Crohn's disease undergoing ileocolectomy: National Surgical Quality Improvement Program database analysis.

Daniel F, El Kouzi Z, Mrad J et al. · 2025 · Updates in surgery

Preoperative use of biologics has been inconsistently reported to be associated with increased frequency of infectious and surgical anastomotic complications in inflammatory bowel disease patients. We aimed to evaluate the rates of 30-day…

View details →
Negative / Null Result ReportMedicine

Psychological mechanisms of change in reducing co-occurring social anxiety and alcohol use: A causal mediation analysis of the online Inroads intervention.

Gückel T, Prior K, Newton NC et al. · 2025 · Behaviour research and therapy

Background Research has documented the prevalence and treatment of co-occurring anxiety and alcohol use, but the mechanisms underlying treatment efficacy, especially in online interventions, remain unclear. This study investigated the…

View details →
Negative / Null Result ReportOpen accessMedicine

Immune dysregulation in gestational diabetes mellitus: placental downregulation of CXCL9 and IL1RL1 and altered immune cell infiltration.

Zhou Z, Huang L, Sheng L et al. · 2026 · Frontiers in cell and developmental biology

Background Immune dysregulation is implicated in pregnancy complications, particularly gestational diabetes mellitus (GDM). This study aimed to identify immune-related genes and characterize immune cell infiltration in GDM placentas.…

View details →
Negative / Null Result ReportOpen accessMedicine

Adolescent binge drinking causes sex-specific deficits in behavioral reactivity, endocrine recovery from stress and altered expression of hypothalamic KCC2 in males.

Büyükdemirtaş B, Benn M, Kwon HB et al. · 2026 · Psychopharmacology

Rationale Binge drinking during adolescence is associated with a higher risk of developing Alcohol Use Disorders and impaired stress reactivity in adulthood. The hypothalamic-pituitary-adrenal axis matures during adolescence and is under…

View details →
Negative / Null Result ReportMedicine

Linking overstory relative density to light availability and understory plant community composition in disturbance-dependent, Pinus rigida -dominated forests of the mid-Atlantic coastal plain, USA

Isaacson BN, Serbin SP, Grabosky JC · 2025 · Forest Ecology and Management.

There is a vigorous debate around whether and how to manage forests for climate mitigation or for other goals such as biodiversity. To achieve any of these goals it is necessary to define the parameters within which they can exist;…

View details →
Negative / Null Result ReportOpen accessMedicine

Subclinical peripheral nerve demyelination without overt symptoms in a family with neuronal intranuclear inclusion disease harboring biallelic repeat expansions.

Zhang H, Zhao T, Zheng H et al. · 2026 · BMC neurology

Neuronal intranuclear inclusion disease (NIID) is a rare, progressive neurodegenerative disorder caused by abnormal GGC repeat expansions in the NOTCH2NLC gene, leading to multisystem involvement. Electrophysiological abnormalities in NIID…

View details →
Negative / Null Result Report

Evaluating Working Memory as a Buffer for Visual Search

Su Z, Wyble B, Fu Y · 2024 · Preprint

This study explores the relationship between working memory and attention during visual search tasks, focusing on how time constraints affect the encoding of visual information into working memory. The research is based on the premise that…

View details →
Negative / Null Result ReportMedicine

Insufficient Evidence for Load as the Primary Cause of Nonspecific (Chronic) Low Back Pain. A Scoping Review.

de Bruin LJE, Hoegh M, Greve C et al. · 2024 · The Journal of orthopaedic and sports physical therapy

OBJECTIVE: To assess the causal role of the relationship between loading and the onset of nonspecific low back pain (NSLBP) and persistence of NSLBP (chronic low back pain [CLBP]). DESIGN : Scoping review. LITERATURE SEARCH : We searched…

View details →
Negative / Null Result ReportOpen accessMedicine

Retraction: miR-365 secreted from M2 Macrophage-derived extracellular vesicles promotes pancreatic ductal adenocarcinoma progression through the BTG2/FAK/AKT axis.

· 2024 · Journal of cellular and molecular medicine

Xin Li, Hao Xu, Jianfeng Yi, Chunlu Dong, Hui Zhang, Zhengfeng Wang, Long Miao, Wence Zhou. miR-365 secreted from M2 Macrophage-derived extracellular vesicles promotes pancreatic ductal adenocarcinoma progression through the BTG2/FAK/AKT…

View details →
Negative / Null Result ReportMedicine

Behavior of Listeria monocytogenes in commercial queso fresco and queso cotija and investigation of salt concentration as a control factor

Andersen Z, Kilgore S, Waite-Cusic J et al. · 2025 · Journal of Dairy Science

Hispanic-style cheeses (HSC), particularly fresh soft varieties, have been associated with numerous outbreaks of Listeria monocytogenes, highlighting the need to identify product characteristics or interventions that could mitigate L.…

View details →
Negative / Null Result ReportOpen accessMedicine

An Occurrence of Mass Psychogenic Illness: LeRoy, New York.

McVige J, Masset L, Mechtler L et al. · 2026 · Journal of child neurology

Mass psychogenic illness (MPI), also known as mass sociogenic illness, is a functional neurologic symptom disorder affecting multiple people simultaneously. This study presents a pediatric MPI outbreak involving abrupt-onset tics in LeRoy,…

View details →
Negative / Null Result ReportOpen accessMedicine

Are KLIC and CRIME-80 scores useful to assist decision-making initially or at the moment of repeat DAIR? - a retrospective study.

Contente J, Ferreira C, Silva M et al. · 2025 · Journal of bone and joint infection

Introduction : Debridement, antibiotics, and implant retention (DAIR) is recommended for early acute postoperative and late acute periprosthetic joint infections (PJIs). The KLIC and CRIME-80 scores have been proposed to predict DAIR…

View details →
Negative / Null Result ReportMedicine

Elevational pattern of species range size of vascular plants in Changbai Mountain, China:A test of Rapo-port's rule.

Li MS, Wu XQ, Zhou YJ et al. · 2024 · Ying yong sheng tai xue bao = The journal of applied ecology

Species range size is closely related to its ability to migrate and adapt to environmental change. Rapoport's rule predicts that species range size would become larger with increasing latitude or elevation. Empirical evidence for…

View details →