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20,261 real negative results, null findings, and replication failures · Negative / Null Result Report. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result ReportMedicine

Proton FLASH preserves neurocognition across delivery techniques: implications for clinical translation in pediatric brain tumors.

Miles, Sforza, Tan et al. · 2026 · bioRxiv : the preprint server for biology

Radiation therapy is integral to the curative treatment of childhood brain tumors but contributes to late neurocognitive impairment in survivors. FLASH (ultra-high dose rate, >40Gy/s) reduces normal-tissue toxicity in preclinical models,…

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Negative / Null Result ReportMedicine

Middle Eastern male ACL-deficient patients exhibit steeper posterior tibial slope than European counterparts: A cross-cultural matched cohort study.

Romandini, AlKhelaifi, Macchiarola et al. · 2026 · Journal of experimental orthopaedics

The posterior tibial slope (PTS) is a key anatomical factor influencing anterior cruciate ligament (ACL) stability. Steeper slopes have been associated with increased anterior tibial translation (ATT) and a higher risk of graft failure…

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Negative / Null Result ReportMedicine

Prognostic value of hematological ratios in sepsis: A prospective observational study of neutrophil-to-lymphocyte, platelet-to-lymphocyte, and monocyte-to-lymphocyte ratios.

Deokate, Acharya, Patil et al. · 2026 · International journal of critical illness and injury science

Early identification of high-risk sepsis patients remains a clinical priority. Hematological ratios such as neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), and monocyte-to-lymphocyte ratio (MLR) have emerged as…

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Negative / Null Result ReportMedicine

Nanostructure and Collagen-Stimulating Activity of Cationic Pentapeptide Lipopeptides.

de Mello, Castelletto, Seitsonen et al. · 2026 · Journal of peptide science : an official publication of the European Peptide Society

The self-assembly in aqueous solutions, cytocompatibility, and collagen production of lipopeptide C 16 -KTTKS and a variant with arginine substitution for lysine, C 16 -RTTRS, are investigated. C 16 -KTTKS is known commercially as Matrixyl…

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Negative / Null Result ReportMedicine

Efficacy of Nurse-Led WIKAP Intervention on Hypoglycemia Coping Confidence and Outcomes in Adolescents with Type 1 Diabetes Mellitus: A Quasi-Experimental Study in Zhijiang, China.

Xiao, Zheng, Guo et al. · 2026 · Patient preference and adherence

Hypoglycemia is a frequent and burdensome complication in adolescents with type 1 diabetes mellitus (T1DM). Despite its high prevalence, structured interventions targeting hypoglycemia coping confidence remain scarce, especially in China.…

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Negative / Null Result ReportMedicine

The effectiveness of a cognitive behavioural therapy for insomnia based intervention to improve sleep quality in nursing home residents, a cluster randomised controlled trial.

Lahaye, Haegdorens, Franck et al. · 2026 · European geriatric medicine

To evaluate the effectiveness of a structured, team-delivered intervention based on cognitive behavioural therapy for insomnia (CBT-I) on sleep and related outcomes in nursing home residents. A cluster randomised controlled trial with…

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Negative / Null Result ReportMedicine

Occurrence of acrylamide and 4-methylimidazole in roasted and ground coffee and the effect of L-asparaginase treatment of green coffee on their levels.

da Costa, Ramirez, de Carvalho et al. · 2026 · Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment

Acrylamide and 4-methylimidazole (4-MEI) are heat-induced contaminants formed during coffee roasting, raising concerns due to their potential toxicological effects. Considering the limited information about the occurrence of these…

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Negative / Null Result ReportMedicine

The impact of universal credit on mental, physical, and financial well-being: longitudinal evidence from the UK household longitudinal survey.

Bai, Kim, Cao et al. · 2026 · Social psychiatry and psychiatric epidemiology

Universal Credit (UC) is a major UK welfare reform that consolidates six means-tested benefits into a single monthly payment, aiming to simplify benefits delivery and incentivize labor market participation. However, concerns have emerged…

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Negative / Null Result ReportMedicine

Comparative bio-efficacy and molecular insights of North-Western Himalayan conifers, Cedrus deodara and Juniperus macropoda essential oils against two storage insect pests.

Guleria, Horijan, Kumar et al. · 2026 · Scientific reports

The study aimed to evaluate fumigation and repellent properties of essential oils (EOs) from Juniperus macropoda leaves and cedarwood, Cedrus deodara against storage pests viz., Tribolium castaneum and Callosobruchus maculatus. Further,…

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Negative / Null Result ReportMedicine

Age-Related Hearing Loss and Cognition: The Role of Bilingualism.

Heidari, Amiri, Mobarakeh · 2026 · Journal of speech, language, and hearing research : JSLHR

Age-related hearing loss (ARHL) has been associated with cognitive decline. Although bilingualism may influence cognitive performance, its interaction with hearing loss remains unclear. This study aimed to investigate the effects of ARHL…

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Negative / Null Result ReportMedicine

Retrospective Propensity-Matched Comparison of Noninvasive Positive Pressure Ventilation Versus High-Flow Nasal Cannula on Reintubation Rates in Neurosurgical Intensive Care Patients.

Wang, Lv, Zeng et al. · 2026 · Neurocritical care

This study compared the effectiveness of noninvasive positive pressure ventilation (NIPPV) and high-flow nasal cannula (HFNC) in preventing reintubation among neurosurgical intensive care patients following extubation. A retrospective…

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