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19,915 real negative results, null findings, and replication failures · Negative / Null Result Report. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result ReportOpen accessMedicine

Measurement Properties and Minimal Detectable Change of the 6-Min Step Test for Estimating Cardiorespiratory Fitness in Hospitalized Individuals After Stroke.

Aguiar Pavesi RO, Boening A, Meyrelles SDS et al. · 2026 · Physiotherapy research international : the journal for researchers and clinicians in physical therapy

Background The 6-minuteute step test is an alternative for estimating cardiorespiratory fitness after stroke. Objective To investigate its measurement properties and minimal detectable change early after stroke. Methods Cross-sectional,…

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Negative / Null Result ReportMedicine

Effect of a Spinal Orthosis With Leaf Spring and Programmable Local Vibration on Kyphosis Angle and Trunk Muscle Strength in Hyperkyphosis: Development and Feasibility Study.

Keshavarzi F, Arazpour M, Behzadipour S · 2026 · JMIR biomedical engineering

Background The application of spinal orthoses and local vibration in the treatment of hyperkyphosis is a developing concept. Further research is needed to determine the impact of leaf springs and local vibration techniques on the…

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Negative / Null Result ReportOpen accessMedicine

Case Report: early regression and bladder-intact survival after limited-course immunotherapy-based systemic therapy in two patients with clinically staged bulky muscle-invasive bladder cancer.

Zhang S, Zhang H, Dong X et al. · 2026 · Frontiers in immunology

Background Radical cystectomy remains a standard curative treatment for muscle-invasive bladder cancer (MIBC). Bladder preservation after systemic therapy without immediate surgery remains investigational and requires careful patient…

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Negative / Null Result ReportOpen accessMedicine

Use of dual ART in individuals with different HBV serological patterns.

Swaine T, Bhagani S · 2026 · Current opinion in HIV and AIDS

Purpose of review Two-drug regimens (2DR) for antiretroviral therapy are increasingly being recommended for people living with HIV to reduce pill burden and reduce short and long-term toxicity. The exclusion of tenofovir and lamivudine or…

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Negative / Null Result ReportOpen accessMedicine

Three-dimensional Bovine Collagen-Elastin Matrix in Soft Tissue Reconstruction: No Detectable Bovine DNA After 1 Year.

Nicklas A, Rudari M, Reidow N et al. · 2026 · Plastic and reconstructive surgery. Global open

Background Postoperative wound healing remains a critical challenge, particularly in complex reconstructions such as free flap surgeries. Despite technical improvements, perfusion-related complications may cause partial flap loss.…

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Negative / Null Result ReportOpen accessMedicine

Serum HMGB1 and Alcohol-Related Liver Disease.

Popiolek I, Hydzik P, Ciszowski K et al. · 2026 · Journal of clinical medicine

Background/Objectives: Alcohol-related liver disease (ALD) lacks widely adopted biomarkers that reflect disease activity and severity. High-mobility group box 1 (HMGB1), a damage-associated molecular pattern, has been implicated in ALD…

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Negative / Null Result ReportMedicine

In Vitro Evaluation of the Antifungal Activity and Cytotoxicity of <i>Sambucus williamsii</i> var. <i>coreana</i> Extract Against <i>Candida albicans</i> and HaCaT Cells.

Yoon HJ, Kim GC, Nam SH · 2026 · Pathogens (Basel, Switzerland)

Background Oral candidiasis is an opportunistic infection caused by Candida albicans (C. albicans) , highlighting the need to evaluate candidate substances that ensure both antifungal efficacy and mucosal safety. This study aimed to assess…

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Negative / Null Result ReportMedicine

SARS-CoV-2 spike-directed T cells and anti-receptor-binding-domain antibodies in hematological patients receiving three mRNA COVID-19 vaccine doses.

Carretero D, Giménez E, Pérez A et al. · 2026 · Enfermedades infecciosas y microbiologia clinica (English ed.)

Introduction Studies assessing SARS-CoV-2 antibodies and functional T-cell responses in hematological patients following receipt of a three-dose mRNA vaccine schedule have yielded conflicting results. Methods We conducted a retrospective…

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Negative / Null Result ReportMedicine

Short-term effects of static stretching versus myofascial release on hamstring tightness and lower extremity function in sedentary IT professionals: a randomized controlled trial.

Anand M, Kashyap R, Bhat P et al. · 2026 · BMC sports science, medicine & rehabilitation

Background Prolonged sedentary work is associated with hamstring tightness, reduced flexibility, and functional limitations among information technology (IT) professionals. Comparative evidence for static stretching and myofascial release…

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Negative / Null Result ReportOpen accessMedicine

Does mRNA-based COVID-19 vaccination in the subacute phase lead to microstructural brain changes? A prospective pilot MRI study using T1 relaxometry.

Willems R, Cappelletti M, Schüre JR et al. · 2026 · Scientific reports

Messenger ribonucleic acid (mRNA)-based vaccines delivered via lipid nanoparticles (LNP) were pivotal in managing the severe acute respiratory syndrome coronavirus (SARS-CoV-2) pandemic. While mild systemic reactions are common after…

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Negative / Null Result ReportOpen accessMedicine

X-rays and gamma rays do not differ in their effectiveness for sterilizing pupae and adults of the mosquito Aedes aegypti (Diptera: Culicidae).

Chen C, Qualls WA, Xue RD et al. · 2026 · Journal of economic entomology

The sterile insect technique (SIT) is increasingly used as an alternative or supplemental tool in the integrated mosquito management toolbox to protect human health worldwide. SIT programs targeting mosquitoes such as Aedes aegypti (L.)…

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Negative / Null Result ReportOpen accessMedicine

Association between anti-Mullerian hormone and antithyroid antibodies detectability and positivity in women assisted at a fertility clinic.

Oliveira YIL, Couto A, Sá PG et al. · 2025 · JBRA assisted reproduction

Objective To evaluate the association between antithyroid antibodies detectability and positivity and ovarian reserve. Additionally, we aimed to evaluate the correlation between TSH levels and parameters of ovarian reserve [anti-Mullerian…

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