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Browse the failure-mode index

19,915 real negative results, null findings, and replication failures · Negative / Null Result Report. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result ReportOpen accessMedicine

Can antioxidants' supplementation modulate the impact of dietary deoxynivalenol and zearalenone co-contamination on the systemic and mucosal immune response of weaned pigs?

Lo Verso L, Lessard M, Lauzon K et al. · 2026 · Journal of animal science

This study aimed to determine the effects of deoxynivalenol (DON) and zearalenone (ZEA) co-contamination on systemic immune responses and intestinal mucosal immunity in weaned piglets and to evaluate the mitigating ability of antioxidant…

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Negative / Null Result ReportMedicine

Comparison of the effects of antibiotic therapy and photobiomodulation with red and infrared lasers on the healing of postextraction sockets of third molars: A randomised controlled trial.

Alves Pereira D, Silva Bonatto M, Souza Santos S et al. · 2025 · Lasers in medical science

The aim of this study was to evaluate the effects of dual-wavelength photobiomodulation (PBMT) compared with antibiotic therapy with amoxicillin on postoperatory healing and symptoms after third molar extraction. Sixty patients were…

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Negative / Null Result ReportMedicine

Beneficial effect of omega-3 fatty acids supplementation on leaky gut, inflammation and oxidative stress in propionic acid-induced autism in aged rats.

Aloud A, Alzahrani H, Arzoo S et al. · 2026 · Acta pharmaceutica (Zagreb, Croatia)

This study examined the effects of omega-3 fatty acids supplementation on gut barrier integrity, systemic inflammation, neurotrans-mission and oxidative stress, in an aged rat model of propionic acid (PPA)-induced neurotoxicity.…

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Negative / Null Result ReportMedicine

Pleiotropic effects of renal denervation beyond blood pressure reduction.

Vakka A, Kyriakoulis KG, Tatakis F et al. · 2026 · Hypertension research : official journal of the Japanese Society of Hypertension

Overactivation of sympathetic nervous system (SNS) has a key role in the pathophysiology of hypertension, as well as in chronic kidney disease, heart failure, atrial fibrillation, type 2 diabetes mellitus, obstructive sleep apnea, and…

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Negative / Null Result ReportOpen accessMedicine

Assessment of "Spin" in the Abstracts of Systematic Reviews in Leading Arthroplasty Journals Over the Past 10 Years: A Cross-Sectional Methodological Study.

Vediya N, Jain V, Sritharan P et al. · 2025 · Arthroplasty today

Background Systematic reviews (SRs) are vital for evidence consolidation in clinical research, utilized for their robust, reproducible methodology. SRs are prone to misrepresentation as they are based on primary studies and the…

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Negative / Null Result ReportMedicine

Cued recall of human motor memory.

Lewis-Hoeber E, Darainy M, Ebrahimi S et al. · 2026 · Journal of neurophysiology

In verbal memory, retrieval cues can facilitate recall of otherwise inaccessible information. Recent work, using passive movements following a motor learning task, suggests that somatic retrieval cues similarly access motor memories. The…

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Negative / Null Result ReportOpen accessMedicine

Oxytocin

· 2006

Oxytocin is an essential lactation hormone released during breastfeeding that causes milk ejection and appears to have calming effect on the mother.[1] Administration of exogenous oxytocin to mothers having difficulty in breastfeeding has…

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Negative / Null Result ReportMedicine

High flow nasal oxygen for acute hypoxaemic respiratory failure in the intensive care unit: An umbrella review.

Wynne R, Dharmalingam R, Omarit R et al. · 2026 · Australian critical care : official journal of the Confederation of Australian Critical Care Nurses

Objectives To assess whether high flow nasal oxygen (HFNO) therapy reduces the need for endotracheal intubation in adults with acute hypoxaemic respiratory failure (AHRF) in the intensive care unit (ICU). Methods Systematic reviews were…

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Negative / Null Result ReportMedicine

Dietary Ewe's Yogurt Intake Selectively Modulates HDL Subfractions Without Altering LDL Particle Size in Women: A Six-Week Intervention Study.

Gažarová M, Lenártová P, Kopčeková J et al. · 2026 · Nutrients

Background/Objectives: The aim of the study was to assess the metabolic response of women to a six-week consumption of full-fat sheep milk yogurt, with a focus on cardiovascular risk markers, lipid profile, and subfractions of low-density…

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Negative / Null Result Report

Gestational diabetes mellitus and intrahepatic cholestasis of pregnancy – does metformin treatment affect the course of ICP: results of an observational case-control study

Majewska A, J NW, Chambers J et al. · 2026 · Preprint

Abstract Objective: To evaluate the association between metformin treatment in gestational diabetes mellitus and severity of intrahepatic cholestasis of pregnancy (ICP). Design: Retrospective multicentre cohort study. Setting: Six…

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Negative / Null Result ReportMedicine

Impact of serum potassium levels on success of electrical cardioversion in atrial fibrillation.

Vogel MJ, Hacker K, Herting J et al. · 2026 · Clinical research in cardiology : official journal of the German Cardiac Society

Background Electrical cardioversion (ECV) is an effective treatment for restoring sinus rhythm in supraventricular tachycardias such as atrial fibrillation (AFib) and atrial flutter (AFlu). In clinical practice, serum potassium is often…

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Negative / Null Result ReportMedicine

Does attachment change serve as a theory-specific mediator of depression reduction in interpersonal psychotherapy versus cognitive behavioral therapy?

Abapolnikova M, Coyne AE, Glushka L et al. · 2026 · Psychotherapy research : journal of the Society for Psychotherapy Research

Objective Although interpersonal psychotherapy (IPT) and cognitive behavioral therapy (CBT) for depression are comparably efficacious, less is known about the respective patient-level processes that help transmit their beneficial effect.…

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Negative / Null Result ReportMedicine

Role of sitagliptin in diabetes-induced testicular damage via the Fas/FasL signalling pathway.

Ersoy O, Kizilay G · 2026 · Biotechnic & histochemistry : official publication of the Biological Stain Commission

Clinical and experimental studies have shown that sitagliptin regulates blood glucose levels. This study was designed because it is thought that sitagliptin may reduce diabetes-induced apoptosis in testes by affecting blood glucose levels…

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Negative / Null Result ReportOpen accessMedicine

Effects of Using Effective Microorganisms (EMs) and Zeolite on the Development of Productivity and Air and Litter Quality in Broiler Chicken Rearing.

Sosnówka-Czajka E, Skomorucha I, Wojtysiak D et al. · 2026 · Animals : an open access journal from MDPI

The growing greenhouse gas emissions from agricultural production are increasing the pressure on poultry producers to use practices that reduce the environmental impact of farms, mainly by reducing ammonia emissions. The study evaluated…

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Negative / Null Result ReportMedicine

Influence of Microstructure on Mechanical and Electrical Properties of Indium Tin Oxide Thin Films Deposited on Polymer Substrates.

Chommaux T, Renault PO, Godard P et al. · 2026 · ACS applied materials & interfaces

The electrical and mechanical behaviors of 400 nm thick indium tin oxide (ITO) thin films on polyimide substrates were investigated by means of electrical resistivity and synchrotron X-ray diffraction (XRD) measurements during equibiaxial…

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Negative / Null Result ReportMedicine

Effect of temporary suspension of chronic immunosuppressive drugs on day-90 mortality and ICU-acquired infections among critically Ill patients with solid organ transplant: a retrospective multicenter study.

Vaidie J, Demiselle J, Gabriel A et al. · 2025 · Intensive care medicine

Purpose Decision-making for management of immunosuppressive drugs in solid organ transplant patients admitted to the ICU remains controversial. This study aimed to evaluate the impact of a temporary suspension strategy (interruption of…

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