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Browse the failure-mode index

20,261 real negative results, null findings, and replication failures · Negative / Null Result Report. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result Report

Neurofeedback did reduce medication for ADHD

Alison Knopf · 2020 · Alcoholism & Drug Abuse Weekly

Many parents are opposed to the idea of stimulant medication for their child's moderate to severe attention deficit hyperactivity disorder (ADHD), even though it is the first‐line recommended treatment. A recent study has found that…

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Negative / Null Result ReportOpen accessMedicine

Intrapartum Molecular Detection of Group B <i>Streptococcus</i>: Real-World Evaluation of Multiple Point-of-Care Platforms and the Potential Role of Lysis Efficiency.

Serrari M, Bianchi L, Tré-Hardy M et al. · 2026 · Microorganisms

Antenatal screening for Group B Streptococcus (GBS) does not always reflect intrapartum colonisation status, and rapid molecular point-of-care tests (POCT) have been developed to enable real-time detection during labour. This prospective…

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Negative / Null Result ReportOpen accessMedicine

Risk factors and a prediction model for false-negative diagnosis in repeat EUS-FNA/B of pancreatic solid lesions following initially nondiagnostic or inconclusive findings.

Ma JY, Jiang W, Cheng B et al. · 2026 · Endoscopic ultrasound

Background and objectives Repeated EUS-guided fine-needle aspiration/biopsy (rEUS-FNA/B) is recommended in solid pancreatic lesions (SPLs) with inconclusive initial results. However, even rEUS-FNA/B cannot completely eliminate false…

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Negative / Null Result ReportMedicine

When pooling fails: low-intensity <i>Angiostrongylus cantonensis</i> infections in <i>Theba pisana</i> result in false-negativity.

Anettová L, Jaume-Ramis S, Paredes-Esquivel C et al. · 2026 · Journal of helminthology

Pooling of gastropod samples is frequently used in surveys of the neurotropic nematode Angiostrongylus cantonensis to reduce cost and processing time. Here we highlight a potential limitation of this technique using the snail Theba pisana…

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Negative / Null Result ReportMedicine

DNA metabarcoding for food authentication: identification of freshwater, marine, and terrestrial gastropods in commercial food products.

Andronache J, Cichna-Markl M, Dobrovolny S et al. · 2026 · NPJ science of food

Food fraud through species substitution has been reported for edible gastropods, particularly in processed products where morphological identification is not feasible. DNA-based methods have been used to identify gastropod species in food…

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Negative / Null Result ReportMedicine

Decreased evertor strength following peroneus longus tendon harvest for anterior cruciate ligament reconstruction : an isokinetic muscle strength testing study.

Kotian RN, Ajoy SM, Panduranga R et al. · 2026 · The bone & joint journal

Aims There are conflicting results in the literature regarding the safety of the peroneus longus tendon (PLT) as a potential graft for anterior cruciate ligament (ACL) reconstruction, and no long-term studies with objective assessment…

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Negative / Null Result ReportOpen accessMedicine

Predictive Factors of Functional Prognosis in Patients with Rhegmatogenous Retinal Detachment Treated by Pars Plana Vitrectomy-A Retrospective Study.

Chereji G, Chelaru VF, Nicoară SD · 2026 · Diagnostics (Basel, Switzerland)

Background/Objectives : Rhegmatogenous retinal detachment (RRD) is a surgical emergency that causes vision loss if not properly treated. Pars plana vitrectomy (PPV) is the preferred procedure for most complex RRD cases, with a high success…

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Negative / Null Result ReportOpen accessMedicine

Genetically predicted TTK inhibition and its association with reduced breast cancer risk: a two-step Mendelian randomization study of potential gut microbiome mediation.

Liu J, Liu M, Xu Y et al. · 2026 · Clinics (Sao Paulo, Brazil)

Background BOS172722, a selective TTK inhibitor, shows promise for Breast Cancer (BC) treatment. The role of gut microbiota as a potential mediator in this process has not been established. This Mendelian Randomization (MR) study…

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Negative / Null Result ReportMedicine

Effects of different hyrax maxillary expansion protocols compared with novel magnetic expansion on the pharyngeal airway and maxillary sinus spaces: A retrospective CBCT-based observational study.

Algahefi AL, Alhammadi MS, Li Z et al. · 2026 · American journal of otolaryngology

Purpose To evaluate three-dimensional changes in the maxillary sinus (MS) and pharyngeal airway space (PAS) following rapid (RME), slow (SME), and magnetic maxillary expansion (MME) using cone-beam computed tomography (CBCT). Methods This…

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Negative / Null Result ReportOpen accessMedicine

Comparison of Lower Limb Muscle Strength Imbalances and Gait Performance in Postmenopausal Women with Healthy and Low Bone Mineral Density.

Svobodová L, Kasović M, Vodicka T et al. · 2026 · International journal of women's health

Introduction Osteoporosis and osteopenia increase the risk of fractures, impair physical function, and may lead to loss of independence in postmenopausal women. This study examined differences in muscle strength imbalances and gait…

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Negative / Null Result ReportOpen accessMedicine

Assessment of changes in selected parameters of Arnett's soft tissue cephalometric analysis (STCA) in patients undergoing SARME/SARPE.

Nowak R, Olejnik A, Zawiślak E et al. · 2026 · Head & face medicine

Background Maxillary constriction in adults often requires surgically assisted maxillary expansion. While skeletal and dental changes are well described, soft-tissue effects remain less clear. This study evaluated soft-tissue changes using…

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Negative / Null Result ReportOpen accessMedicine

Impact of therapeutic oral health education program in individuals with systemic sclerosis: A prospective study.

Mahajan A, Upadhyay M, Reddy RN et al. · 2026 · Journal of education and health promotion

Background Systemic sclerosis is an autoimmune disorder characterized by progressive fibrosis which affects skin and internal organs. There is also involvement of oral cavity seen as microstomia which affects oral hygiene and subsequently,…

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Negative / Null Result ReportOpen accessMedicine

Assessment of apical debris extrusion with three nickel-titanium rotary systems using conventional and lyophilization-based quantification methods.

Hegde NN, Attavar S, Banerjee A et al. · 2026 · Journal of conservative dentistry and endodontics

Background Apical extrusion of debris during root canal preparation is inevitable and may contribute to postoperative pain and periapical inflammation. The extent of extrusion varies with instrument design and motion. ProTaper Next (PTN),…

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Negative / Null Result ReportOpen accessMedicine

Shear Bond Strength of a Light-Cured and a Dual-Cured Universal Adhesive to Primary and Permanent Dentin: An In Vitro Study.

Fousekis E, Arhakis A, Arapostathis K et al. · 2026 · Biomimetics (Basel, Switzerland)

The aim of the study was to evaluate the immediate and aged shear bond strength (SBS) of a dual-cured and a light-cured universal adhesive to primary and permanent dentin. Twenty caries-free primary molars and twenty permanent third molars…

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Negative / Null Result ReportOpen accessMedicine

Intraperitoneal Polypropylene Mesh in Clean, Potentially Septic, and Controlled Contamination Fields: An Experimental Rat Study.

Makrantonakis A, Mantzoros I, Ioannidis O et al. · 2026 · Medicina (Kaunas, Lithuania)

Background and Objectives : Intraperitoneal onlay mesh (IPOM) reduces ventral/incisional hernia recurrence but raises concern for adhesions and infection, particularly when the operative field is not strictly clean. We aimed to determine…

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Negative / Null Result ReportOpen accessMedicine

Prognostic Value of the Platelet-to-Lymphocyte Ratio in Patients With Acute Coronary Syndrome and Its Correlation With Angiographic Findings.

Seetharama DB, Prasad K, Prakash VR et al. · 2026 · Cureus

Introduction Acute coronary syndrome (ACS) is a major manifestation of coronary heart disease and is associated with significant morbidity and mortality. Inflammatory and thrombotic mechanisms play an important role in its pathogenesis.…

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