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19,915 real negative results, null findings, and replication failures · Negative / Null Result Report. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result ReportOpen accessMedicine

Long-Term Impact of Orthodontic Treatment on Oral Behaviours, Temporomandibular Disorder-Related Pain, and Anxiety: An 18-Month Prospective Study.

Reda B, Zanon G, Contardo L et al. · 2025 · Orthodontics & craniofacial research

Objective Orthodontic treatment is a common approach for correcting malocclusion but is often associated with discomfort. The aim of this study was to assess the longitudinal changes in oral behaviours, temporomandibular disorder…

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Negative / Null Result ReportMedicine

Somatic symptom distress is not related to cardioceptive accuracy.

Petzke TM, Köteles F, Pohl A et al. · 2024 · Journal of psychosomatic research

Objective (Cardiac) interoception was long considered a key mechanism behind symptom perception in persistent somatic symptoms (PSS). In this study, we aimed to extend earlier findings to clarify this potential interoceptive mechanisms of…

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Negative / Null Result ReportMedicine

Efficacy of Low-dose Aspirin in Preventing Hypertensive Disorders of Pregnancy in Women with Systemic Lupus Erythematosus: A Single-Center Retrospective Cohort Study.

Kohno C, Higuchi A, Miyagawa E et al. · 2026 · Modern rheumatology

Objectives Low-dose aspirin (LDA) is widely recommended to prevent hypertensive disorders of pregnancy (HDP). However, the evidence of its effectiveness in pregnancies with systemic lupus erythematosus (SLE) remains limited. This study…

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Negative / Null Result ReportOpen accessMedicine

Lurasidone

· 2006

Lurasidone is more than 99% bound to plasma proteins, so it is unlikely that the drug would be excreted into milk in sufficient amounts to affect a breastfed infant. Data from one mother-infant pair appears to support the poor excretion…

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Negative / Null Result ReportOpen accessMedicine

The Effects of Nitrate on Brown Fat Fraction and Activation in Older Adults With Type 2 Diabetes: A Randomised, Double-Blind and Placebo-Controlled Crossover Trial.

Neal RA, Corbett J, Costello JT et al. · 2026 · European journal of sport science

Type 2 diabetes mellitus (T2DM) is a metabolic disease characterised by chronic hyperglycaemia, whereas obesity is a major risk factor which increases morbidity and mortality. Treatments that alter white adipose tissue to express a…

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Negative / Null Result ReportMedicine

Role of Antipsychotic Agents for Adjunct Sedation.

DeGrado J, Devlin JW · 2025 · Critical care clinics

Antipsychotics are an attractive option for adjunctive sedation in critically ill adults given their sedating effects, short duration of action, lack of effect on respiratory drive, and multiple routes of administration but high-quality…

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Negative / Null Result ReportOpen accessMedicine

Assessment of Eating Behavior and Genetic Risk Factors for Metabolic Syndrome.

Turmanbayeva A, Sadykova K, Nuskabayeva G et al. · 2026 · Journal of clinical medicine

Background : Metabolic syndrome (MetS) is influenced by behavioral and genetic factors, yet evidence on eating behavior patterns and related genetic polymorphisms in Central Asian populations remains limited. Aim: The aim of this study was…

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Negative / Null Result ReportOpen accessMedicine

Visual processing and interference performance influences on knee angular impulse in ACLR individuals: a cognitive-biomechanical analysis of drop-jumps.

Santamaria-Guzman K, Holmes H, Kosek J et al. · 2026 · Archives of orthopaedic and trauma surgery

Introduction Visual processing speed and cognitive interference control are critical for athletic performance and Anterior Cruciate Ligament (ACL) injury risk. However, how these cognitive functions relate to biomechanical performance…

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Negative / Null Result ReportOpen accessMedicine

A high-risk perioperative atrial fibrillation phenotype and early outcomes after isolated coronary artery bypass grafting.

Khalil E, Yüksel B · 2026 · Archives of medical sciences. Atherosclerotic diseases

Introduction Perioperative atrial fibrillation (POAF) remains the most common arrhythmic complication occurring in the setting of isolated coronary artery bypass grafting (CABG), and it is now being increasingly recognised as a marker of…

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Negative / Null Result ReportOpen accessMedicine

Association between Levels of Alcohol Use, Perceived HIV Risk, and Untreated HIV Among Persons at Alcohol-Serving Venues in Kenya and Uganda.

Beesiga B, Litunya J, Nakato JZ et al. · 2026 · AIDS and behavior

Alcohol-serving venues in East Africa are high-risk environments for HIV transmission but few studies in sub-Saharan Africa (SSA) have examined perceived HIV risk and sexual risk behaviors by alcohol use levels on a broader population of…

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Negative / Null Result ReportOpen accessMedicine

Effectiveness of Emotion-Focused Cognitive Behaviour Therapy on Emotional Hyporexia Among Adolescent Girls with Eating Problems: A Pilot Study.

Shinde SS, Naik NS, Adhyapak SU et al. · 2025 · Journal of pharmacy & bioallied sciences

Background Emotional hyporexia, a form of intentional food avoidance triggered by emotional distress, presents a growing health concern among adolescent girls. Addressing this behavior through psychological intervention is essential for…

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Negative / Null Result ReportOpen accessMedicine

Blood omega-3 fatty acids and coronary artery stenosis: a postmortem study.

Randall B, Leković A, Nikolić S et al. · 2025 · Lipids in health and disease

The role of omega-3 fatty acids in the atherosclerotic process remains unclear. Early studies demonstrated a profound anti-atherogenic effect of cod liver oil in a pig model, and autopsy reports from Alaska Natives consuming omega-3 rich…

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Negative / Null Result ReportMedicine

Lack of Association of Initial Vasopressor Dosing with Survival and Cardiac Re-Arrest Likelihood After Return of Spontaneous Circulation.

Sharpe AR, Richardson K, Stanton M et al. · 2023 · The Journal of emergency medicine

Background Cardiac arrest occurs in approximately 350,000 patients outside the hospital and approximately 30,000 patients in the emergency department (ED) annually in the United States. When return of spontaneous circulation (ROSC) is…

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Negative / Null Result ReportMedicine

Coagulation factor XI in cirrhosis does not predict thrombo-hemorrhagic complications and hepatic decompensation.

Zanetto A, Campello E, Spiezia L et al. · 2024 · Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver

Introduction Factor XI (FXI) is associated with thrombosis in patients without liver disease, but it alterations and prognostic value in cirrhosis are uncertain. Patients and methods We studied a prospective cohort of cirrhosis patients…

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Negative / Null Result ReportOpen accessMedicine

Dietary Diversity Score and Its Sociodemographic Determinants in School-Aged Children: Cross-Sectional Baseline Findings From a Quasi-experimental Study.

Singh T, Kumar S, Sinha S et al. · 2025 · Cureus

Background Dietary diversity is an essential component of nutritional adequacy, particularly for school-aged children who are undergoing rapid physical and cognitive development. Inadequate dietary diversity can lead to micronutrient…

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Negative / Null Result ReportMedicine

Place of Death, Care Intensity, Symptom Prevalence, and Symptom Management for Patients With Stroke at End-of-Life.

Ramsburg H, Hinkle JL, MacKenzie Greenle M · 2026 · The Journal of neuroscience nursing : journal of the American Association of Neuroscience Nurses

Background Each year in the United States, 795,000 people are diagnosed with a new or recurrent stroke, resulting in 165,393 deaths. However, little is known about the quality of end-of-life (EOL) care in this population, including the…

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Negative / Null Result ReportMedicine

Intrapartum Glycemic Control and Clinical Outcomes.

Bitar G, Fishel Bartal M · 2025 · Diabetes spectrum : a publication of the American Diabetes Association

Current recommendations encourage strict intrapartum glycemic control for individuals with diabetes in pregnancy to optimize maternal and neonatal outcomes. However, established evidence is limited in providing a strong association between…

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Negative / Null Result ReportOpen accessMedicine

The effect of centralized care on the management of postoperative fluctuations in plasma sodium concentration after pediatric suprasellar brain tumor surgery.

Hulsmann SC, Zaal DC, van Gestel JPJ et al. · 2026 · Pituitary

PURPOSE: Children undergoing neurosurgery for (supra)sellar tumors are at risk of developing arginine vasopressin-deficiency (AVP-D), which can cause severe sodium fluctuations and associated neurological complications, prolonged…

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