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Browse the failure-mode index

19,915 real negative results, null findings, and replication failures · Negative / Null Result Report. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result ReportMedicine

Update on the utilization of complementary therapies by adolescents with asthma in an urban population.

Soffer GK, Feinberg T, Kroll H et al. · 2025 · The Journal of asthma : official journal of the Association for the Care of Asthma

Objectives To assess the prevalence and perceived efficacy of complementary and alternative medicine (CAM) use among urban adolescents with asthma, building on a previous landmark study, and to determine if CAM use varied by asthma…

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Negative / Null Result ReportOpen accessMedicine

Occurrence of CRISPR-Cas genes and lack of association with antibiotic resistance in Shigella isolates collected from patients with diarrhea in Ahvaz, southwest Iran.

Ekrami A, Taheri B, Daneshfar S et al. · 2025 · BMC infectious diseases

BACKGROUND: So far, few studies have examined the association between CRISPR-Cas and antibiotic resistance in Shigella isolates. Hence, this study sought to address this issue in Shigella species isolated from stool samples of patients…

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Negative / Null Result ReportOpen accessMedicine

Ventricular Tachyarrhythmia in a Newborn Baby.

Maclennan APH, Sitner-Medvedovsky E, Varon D et al. · 2024 · Oxford medical case reports

Supraventricular tachycardia (SVT) is a narrow QRS complex tachyarrhythmia with a heart rate above 220 beats per minute in infants and children. Ventricular tachycardia can be due to electrolyte abnormalities, cardiomyopathies, congenital…

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Negative / Null Result ReportMedicine

Association between exposure to pyrethroids and chlorpyrifos at age 5 years and IQ at age 7 years among children from the Odense Child Cohort, a prospective birth cohort study

Normann SS, Andersen HR, Lund LC et al. · 2025 · Environmental Research

Over the past decade, the use of organophosphate insecticides including chlorpyrifos has faced increasing restrictions due to health concerns, leading to a rise in use of pyrethroids. Concerns about neurodevelopmental insults following…

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Negative / Null Result ReportOpen accessMedicine

Automated CT segmentation of kidneys successfully quantifies changes in total kidney volume in ICU patients, a retrospective cohort study.

Biersma AGW, van Leer B, Renes MH et al. · 2026 · BMC nephrology

BACKGROUND: Kidney function is associated with kidney volume. This study aims to explore automated segmentation for measuring total kidney volume (TKV) and to analyse the association between (changes in) TKV and acute kidney injury (AKI)…

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Negative / Null Result ReportOpen accessMedicine

Prediction of success in sports based on assumed individual genetic predisposition: lack of association with the C > T variant in the ACTN3 gene.

Godina E, Khromov-Borisov N, Bondareva E · 2025 · Journal of physiological anthropology

Background Prediction of sports success (sports talent) based on individual genetic characteristics is the main goal of sports genetics/genomics. Most often, markers of predisposition to speed-strength sports, or endurance, are…

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Negative / Null Result ReportOpen accessMedicine

The effect of serum lipase levels on clinical severity scores and mortality in acute pancreatitis: a retrospective cohort study.

Kilicaslan MB, Dikme O, Girgin MC et al. · 2026 · BMC gastroenterology

Aims This study aimed to investigate the relationship between admission serum lipase levels, prognostic clinical scoring systems, and in-hospital mortality in patients presenting to the emergency department with acute pancreatitis. Methods…

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Negative / Null Result ReportOpen accessMedicine

A Comprehensive Analysis of Predictors of Marginal Ulcers After Roux-en-Y Gastric Bypass: A Cohort Review of 2106 Patients.

Abedalqader T, Migliorini A, Cerecedo LG et al. · 2026 · Medicina (Kaunas, Lithuania)

Background and Objectives: Roux-en-Y gastric bypass (RYGB) is one of the most commonly performed metabolic and bariatric surgeries worldwide. Marginal ulcers (MU) are a common complication following RYGB, yet their pathophysiology and the…

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Negative / Null Result ReportOpen accessMedicine

Lack of Association of Serum MMP-9 Concentration and rs17576 Single Nucleotide Variant <i>MMP-9</i> Gene With the Degree of Coronary Atherosclerosis and Other Risk Factors in Ukrainian Patients With Coronary Artery Disease.

Pogorielova OS, Korniienko VV, Chumachenko YD et al. · 2025 · Cardiology research and practice

This study probes the relationship between serum matrix metalloproteinase-9 (MMP-9) levels, the genetic variant rs17576 in the MMP-9 gene, and the extent of coronary atherosclerosis among Ukrainian patients diagnosed with coronary artery…

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Negative / Null Result ReportMedicine

The acute effects of vaporized cannabis on drivers' hazard perception and risk-taking behaviors in medicinal patients: A within-subjects experiment.

Schiemer C, Horswill MS, Hill A et al. · 2025 · Journal of safety research

Introduction As the medically prescribed use of cannabis flower continues to increase, there is a need to understand how vaporized cannabis can acutely affect driving-related skills and risk-taking behaviors in medicinal populations.…

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Negative / Null Result ReportOpen accessMedicine

Lack of association between the -2549 insertion/deletion variant of vascular endothelial growth factor and coronary artery disease in the Turkish population.

Yigit S, Nursal AF, Celik A et al. · 2024 · Revista da Associacao Medica Brasileira (1992)

Objective Coronary artery disease is the leading cause of death worldwide. Vascular endothelial growth factor is known to induce endothelial cell migration and proliferation, increase vascular permeability, and modulate thrombogenicity.…

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Negative / Null Result ReportOpen accessMedicine

Cord blood DNA methylation and cell-type composition are not significantly associated with severe preeclampsia after cell-type and clinical covariate adjustment.

Yang X, Liu W, Mao Z et al. · 2026 · GigaScience

Background Preeclampsia is a severe pregnancy complication that threatens maternal and neonatal health and well-being. Previous studies on epigenome-wide association studies (EWAS) of preeclampsia produced inconsistent results in cord…

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