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20,261 real negative results, null findings, and replication failures · Negative / Null Result Report. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result ReportOpen accessMedicine

Association between maternal serum levels of Alpha-Fetoprotein and eruption timing of the first central deciduous tooth: a cross-sectional study.

Faghihian E, Ghobadi S, Rezaei R et al. · 2025 · The Saudi dental journal

The current study investigated the relationship between the first central deciduous tooth eruption time and serum levels of maternal alpha-fetoprotein and related multiple of the median (MoM). The cross-sectional study was performed on a…

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Negative / Null Result ReportOpen accessMedicine

Exploring the effects of faecal microbiota transplantation on cognitive function: A review of clinical trials.

Alaeddin S, Chatterjee A, Roberts TL et al. · 2025 · Brain, behavior, & immunity - health

Faecal Microbiota Transplantation (FMT) is a widely used microbiota-modulation technique to treat recurrent Clostridioides difficile infections (rCDI). Rodent studies and clinical trials on probiotic interventions indicate that alterations…

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Negative / Null Result ReportMedicine

Effects of HIV and Adverse Childhood Experiences on Neurocognition.

Inman EM, Inman EM, Ramsammy CW et al. · 2026 · Journal of acquired immune deficiency syndromes (1999)

Background Both HIV and adverse childhood experiences (ACEs) can affect neurocognitive performance. Among youth with perinatal HIV (PHIV), living with a chronic viral infection and experiencing ACEs simultaneously may result in an…

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Negative / Null Result ReportOpen accessMedicine

Use of alteplase continuous rate infusion, pentoxifylline, and cyproheptadine in association or not, in acute feline aortic thromboembolism: a study of nine cats.

Ray CC, Wolf J, Guillaumin J · 2025 · Frontiers in veterinary science

Introduction Locomotion improvement without serious complications is the main goal of treatment for feline aortic thromboembolism (FATE). We aimed to describe the survival and functional recovery of cardiogenic FATE treated with tissue…

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Negative / Null Result ReportOpen accessMedicine

The effect of intraoperative low-dose ketamine versus dexmedetomidine infusion on postoperative bowel recovery in patients undergoing gastrointestinal malignancy surgeries: Placebo-controlled, randomized trial.

Kumar SK, Misra S, Behera BK et al. · 2025 · Journal of anaesthesiology, clinical pharmacology

Background and aims No studies have compared the effects of ketamine and dexmedetomidine on bowel recovery. We evaluated the effects of intraoperative low-dose ketamine or dexmedetomidine infusion on postoperative bowel recovery in…

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Negative / Null Result ReportMedicine

Extent of Lymphadenectomy for Surgical Management of Right-Sided Colon Cancer: The Randomized Phase III RELARC Trial.

Lu J, Xing J, Zang L et al. · 2024 · Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Purpose Complete mesocolic excision (CME) is being increasingly used for the treatment of right-sided colon cancer, although there is still no strong evidence that CME provides better long-term oncological outcomes than D2 dissection. The…

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Negative / Null Result ReportOpen accessMedicine

The relationship between glaucoma and an electronic frailty index with the cumulative incidence of healthcare encounters for falls and fractures in older adults.

Duy WD, Pajewski NM, Williamson JD et al. · 2025 · The Journal of frailty & aging

Objective To compare the association of glaucoma and glaucoma suspect diagnoses with frailty, quantified via an electronic frailty index (eFI), and to evaluate whether a glaucoma diagnosis moderates the association between frailty and the…

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Negative / Null Result ReportMedicine

Racial and ethnic disparities in the usage and outcomes of ischemic stroke treatment in the United States.

Metcalf D, Zhang D · 2023 · Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association

Objectives This study explores racial and ethnic differences in 1) receiving tissue plasminogen activator (tPA) and endovascular thrombectomy (EVT) as treatment for ischemic stroke and 2) outcomes and quality of care after use of tPA or…

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Negative / Null Result ReportMedicine

Association Between Continuous Kidney Replacement Therapy Clearance and Outcome in Pediatric Patients With Hyperammonemia Not Due to Inborn Error of Metabolism.

Starr MC, Cater DT, Wilson AC et al. · 2022 · Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies

Objectives To describe a single-center experience of pediatric patients with hyperammonemia not due to inborn errors of metabolism and determine the association between use of continuous kidney replacement therapy (CKRT) treatment and…

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Negative / Null Result ReportOpen accessMedicine

Discrete Repetition Effects for Visual Words Compared to Faces and Animals, but No Modulation by Expectation: An Event-Related Potential Study.

Song B, Sommer W, Maurer U · 2025 · The European journal of neuroscience

Repetition suppression (RS) refers to the reduction of neuronal responses to repeated stimuli as compared to nonrepeated stimuli. The predictive coding account of RS proposes that its magnitude is modulated by repetition probability…

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Negative / Null Result ReportMedicine

Devaluation of NoGo stimuli is both robust and fragile.

Liu H, Holland RW, Blechert J et al. · 2022 · Cognition & emotion

Consistently not responding to stimuli during go/no-go training leads to lower evaluations of these NoGo stimuli. How this NoGo-devaluation-effect can be explained has remained unclear. Here, we ran three experiments to test the hypothesis…

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Negative / Null Result ReportMedicine

Impact of antibiotic cured chronic endometritis on perinatal outcomes: Re-evaluation of a cohort study with a detailed follow-up.

Zhang Q, Yang G, Xiong Y et al. · 2023 · American journal of reproductive immunology (New York, N.Y. : 1989)

Problem The impact of antibiotic-cured chronic endometritis (CE) on perinatal outcomes of patients conceived with frozen embryo transfer (FET) was unclear. Method This study was to re-evaluate the perinatal outcomes of a cohort of…

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Negative / Null Result ReportOpen accessMedicine

Association between maternal and perinatal outcomes and histological changes in the placenta of patients with Covid-19: A cohort study.

Rocha de Souza L, Ramos Amorim MM, Souza AS et al. · 2024 · Medicine

Although studies evaluated placental involvement in Covid-19 patients, few have assessed its association with clinical repercussions. The study aimed to determine the association between the clinical status and maternal and perinatal…

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Negative / Null Result ReportMedicine

The distribution of the Lansing Effect across animal species.

Ivimey-Cook ER, Shorr S, Moorad JA · 2023 · Evolution; international journal of organic evolution

Maternal senescence is the reduction in individual performance associated with increased maternal age at conception. When manifested on adult lifespan, this phenomenon is known as the "Lansing Effect." Single-species studies report both…

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Negative / Null Result ReportOpen accessMedicine

An Exploratory Analysis of Essential Tremor and Associated Phenotypes.

Gharibian D, Medeiros M, Dion PA et al. · 2026 · Tremor and other hyperkinetic movements (New York, N.Y.)

Essential Tremor (ET) is a highly heterogeneous movement disorder with a strong genetic basis. However, the etiology of ET is unclear, largely due to its clinical heterogeneity and frequently observed comorbidities. We conducted a…

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Negative / Null Result ReportMedicine

New Morbidities During Critical Illness and Associated Risk of ICU Readmission: Virtual Pediatric Systems Cohort, 2017-2020.

Heneghan JA, Akande MY, Ramgopal S et al. · 2024 · Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies

Objectives To describe change in Functional Status Scale (FSS) associated with critical illness and assess associated development of new morbidities with PICU readmission. Design Retrospective, cross-sectional cohort study using the…

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