19,915 real negative results, null findings, and replication failures · Negative / Null Result Report. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Perez PN, Smesseim I, Sterman DH · 2026 · Immunotherapy
Lung cancer is the leading cause of cancer deaths, and despite therapeutic advances, recurrence and resistance persist. Local tumor ablation can function as an in situ vaccine, but thermal techniques may disrupt antigen and extracellular…
View details →Gondi V, Pugh SL, Mehta MP et al. · 2025 · Journal of clinical oncology : official journal of the American Society of Clinical Oncology
Purpose Hippocampal avoidance (HA) during therapeutic whole-brain radiotherapy reduces the risk of neurocognitive function (NCF) toxicity in patients with brain metastasis. This trial hypothesized that HA during prophylactic cranial…
View details →Versteegen E, Wang A, Wang X et al. · 2025 · Aquatic toxicology (Amsterdam, Netherlands)
Pharmaceutical contamination in aquatic environments, particularly from neuroactive drugs like antidepressants, potentially affects the behaviour of non-target organisms due to their effects on conserved neuroendocrine systems. Behavioural…
View details →Navarrete Sánchez RA, Tognetti PM, Maddonni GA · 2025 · European Journal of Agronomy.
Maize crops are exposed to heat stress, water restrictions, or combined stress during vegetative stages, which can immediately limit crop growth and extend into the flowering period, affecting grain yield. This study evaluated the effects…
View details →Firlana CR, Emril DR, Syahrizal D et al. · 2026 · Narra J
Sciatic nerve injury results in motor dysfunction and muscle atrophy, with limited effective therapies. Umbilical cord-derived mesenchymal stem cells (UC-MSCs) may promote neuromuscular recovery, but their effects on functional and muscle…
View details →Rupietta AE, Meyer T, Margraf J et al. · 2025 · Preprint
Background: Cognitive theories on trauma memory postulate that trauma-related intrusions are associated with more data-driven and less contextual processing. However, contextualisation can be enhanced via verbalization, suggesting that…
View details →Lee NH, Kim B, Yoo KH · 2025 · Cancer research and treatment
Purpose Mesenchymal stromal cells (MSCs), while regarded as promising immunomodulatory tools, have raised concerns in recent studies for their potential to promote tumor growth or facilitate immune evasion. These risks are particularly…
View details →Telfar-Barnard L, Beautrais A, Anglemyer A · 2025 · Annals of internal medicine
Background There have been multiple changes to the Arms Act 1983 in Aotearoa New Zealand (NZ) which have subsequently been associated with reductions in firearm-related suicide. In response to the worst mass shooting in NZ's history,…
View details →Kougkas N, Skouvaklidou E, Tsafis K et al. · 2026 · Clinical and experimental rheumatology
Objectives Janus kinase inhibitors (JAKi) are increasingly used to treat autoimmune rheumatic diseases (ARDs), despite concerns regarding their potential cardiovascular risks. Cardiac strain, a sensitive marker for subclinical myocardial…
View details →Büyükpolat M, Aydın N, Eryılmaz B et al. · 2025 · BMC oral health
OBJECTIVE: The use of polishing pastes in the final surface preparation of resin composite restorations has become increasingly common. This study aimed to evaluate the effects of polishing pastes containing abrasives of different particle…
View details →Rasmussen MIS, Hansen ML, Pellicer A et al. · 2026 · JAMA pediatrics
Importance Cerebral oximetry monitoring in the first 72 hours after birth has not been shown to reduce death or severe brain injury at 36 weeks' postmenstrual age in extremely preterm infants. The long-term effects remain uncertain.…
View details →Rossi HS, Mykkänen AK, Teppo AM et al. · 2025 · Journal of equine veterinary science
Pneumonia is a common condition in young, hospitalized foals, causing accumulation of inflammatory secretions to the airways. In humans, respiratory physiotherapy is commonly used as a supplementary treatment for pneumonia with varying…
View details →Suvorov VV, Sayitkuliev DB · 2026 · Diseases (Basel, Switzerland)
The development of sternal infection in neonates after cardiac defect correction using median sternotomy is a serious complication, increasing the length of hospital stay, mortality, and treatment costs. One effective method for preventing…
View details →de Lima Cruz GF, Pereira OG, Alves WS et al. · 2025 · Tropical animal health and production
Tropical grasses are widely used for silage, but their high fiber content and variable quality often limit ruminal degradation and animal performance. Strategies such as optimizing regrowth age (RA) and applying fibrolytic enzymes may help…
View details →Sadeghi M, Shahrooz S, Aghamohammadi M et al. · 2025 · BMC research notes
Objective Asthma is a common multifactorial inflammatory disease affecting both children and adults. Various cells and cytokines contribute to this inflammatory process. Smooth muscle contraction, vascular congestion, and airway edema lead…
View details →Pan X, Sarker S, Yu JJ et al. · 2026 · Insects
High rates of pest infestations are frequently reported in low-income homes in the U.S. However, even with access to effective insecticides, most residents are unaware of how to properly control indoor pests. We designed and evaluated the…
View details →Kass C, Katz-Greenberg G, Bodner J et al. · 2025 · Transplant immunology
Purpose Belatacept has been associated with less de novo specific antibody (dnDSA) development, but few publications have compared the incidence of dnDSA development between tacrolimus and belatacept-based immunosuppression regimens. The…
View details →Ferreira RD, Faleiros Ferreira CH, Gonçalves-Ferri WA · 2025 · Preprint
Background Inhaled nitric oxide (iNO) is a standard treatment for neonatal pulmonary hypertension in high-resource settings. Yet, its efficacy and cost-effectiveness in low- and middle-income countries (LMICs) remain underexplored. This…
View details →Zhang Y, Pan J, Hou J et al. · 2025 · Medicine
Rationale Asthenozoospermia (AZS), a leading cause of male infertility, frequently results from genetic defects that disrupt flagellar assembly. Mutations in the DNAH11 gene can cause abnormal dynein arm structures, leading to AZS and…
View details →Masri A, Tully TN, Como K et al. · 2025 · Journal of avian medicine and surgery
Euthanasia is a common veterinary medical procedure performed on terminally ill backyard chickens ( Gallus gallus domesticus ). To reduce stress for these animals, it is important to develop a euthanasia protocol that provides a rapid and…
View details →Lee JH, Hwang K, Jeong WK · 2026 · Clinics in orthopedic surgery
Background Arthroscopic rotator cuff repair is widely performed; yet tendon healing failure still occurs in some cases and remains a challenge. To address this issue, several studies have investigated intraoperative injection or patch…
View details →Cuadrado C, Breedlove C, Toro H · 2025 · Avian diseases
Vaccination with a recombinant Newcastle disease virus (NDV) LaSota (LS) strain expressing Arkansas (Ark) -type infectious bronchitis virus (IBV) spike ectodomain (Se) protein and granulocyte-macrophage colony-stimulating factor (GMCSF)…
View details →Daudi S, Zampelis V, Belfrage O et al. · 2025 · The bone & joint journal
Aims Short, uncemented hip stems might provide a favourable alternative in total hip arthroplasty (THA) by preserving proximal bone mass through reduced strain-adaptive remodelling. We evaluated and compared the migration and…
View details →Gates RS, McCoy K, Stewart J et al. · 2026 · Surgery
Background Timely diagnosis and treatment of primary hyperparathyroidism requires a high index of suspicion and collaboration across specialties. The diagnosis often is overlooked. This study aimed to determine whether the introduction of…
View details →Busanello A, Koller OG, Menezes VM et al. · 2025 · The British journal of nutrition
The objective of this study was to evaluate the impact of incorporating group-based nutritional education into usual care on adherence to nutritional counselling among outpatients with type 2 diabetes (T2DM). This parallel-group,…
View details →Williams KG, Constantine EP, Whitney KE et al. · 2026 · Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA
Purpose To determine whether patients undergoing arthroscopic partial meniscectomy (APM) with synovitis treated by synovectomy exhibit similar outcomes to those without synovitis after 24-month follow-up. Methods A total of 181 patients…
View details →Lopresti AL, Smith SJ · 2025 · Clinical drug investigation
Background and objectives Bacopa monnieri is a plant used in Ayurvedic medicine with traditional uses for memory and cognitive function. The objective of this study was to examine the effects of supplementation with a Bacopa monnieri…
View details →Timmermans J, Van Goethem B, Stock E et al. · 2026 · Veterinary surgery : VS
Objective To evaluate the soft palate thickness in brachycephalic dogs 3 months after performing folded flap palatoplasty (FFP) or standard staphylectomy (STS). Study design Prospective, observational study. Animals Twenty client-owned…
View details →Foddai M, Carter CG, Wood AT et al. · 2025 · Comparative Biochemistry and Physiology, Part A
Sustained aerobic training is suggested to enhance cardiac performance and growth in farmed salmonids, but its effects under suboptimum elevated temperatures remain unclear. This study examined whether continuous training at different…
View details →Modica V, Glávits R, Clewell A et al. · 2025 · Preprint
Anaerostipes caccae CLB101 (CLB101) is an obligate, anaerobic bacteria that was isolated from the stool of a healthy infant. Due to its ability to produce butyrate and its potential promotion of microbiome health through multiple…
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