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Browse the failure-mode index

19,906 real negative results, null findings, and replication failures · Negative / Null Result Report. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result ReportMedicine

Transmucosal detomidine gel induces emesis in approximately half of cats presenting for dietary indiscretion.

Neufeld MR, Hanson KR, Mochel JP et al. · 2026 · Journal of the American Veterinary Medical Association

Objective To evaluate the efficacy and safety of transmucosal administration of detomidine gel to induce emesis in cats. Methods Cats presenting on an emergency basis due to dietary indiscretion were eligible for enrollment at 2 emergency…

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Negative / Null Result ReportOpen accessMedicine

Unplanned hospital presentations in oncology patients receiving chemotherapy: a secondary analysis of a randomized controlled trial to explore opportunities for improving supportive care.

Kim B, Boustany C, Fethney J et al. · 2026 · Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer

Purpose This study aimed to report the incidence, common reasons, and associated risk factors for unplanned hospital presentations during chemotherapy treatment. Methods A secondary analysis using data from a randomized controlled trial…

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Negative / Null Result ReportMedicine

Acute dysfunction of granular-based anaerobic reactor triggered by short-term exposure to colloid-containing wastewater: from irreversible sludge flotation to systemic failure.

Xie L, Lian H, Yin H et al. · 2026 · Bioresource technology

Inert colloidal substances (ICS) are ubiquitous in industrial wastewater; however, their effects on the stability of anaerobic granular sludge beds remain insufficiently understood. Using polyacrylamide as a model ICS, this study…

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Negative / Null Result ReportMedicine

Efficacy and safety of cannabidiol oil in psoriasis: a randomized, double-blind, placebo-controlled trial.

Roongpisuthipong W, Klangjareonchai T, Kurathong S et al. · 2026 · The Journal of dermatological treatment

Background The management of psoriasis presents challenges, prompting many patients to seek alternative treatments. Cannabidiol (CBD) has demonstrated potential antioxidant and anti-inflammatory properties which may offer therapeutic…

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Negative / Null Result ReportMedicine

Effects of ultralow oxygen treatments at low temperature on survival of spotted wing drosophila, Drosophila suzukii (Diptera: Drosophilidae), in blueberries and sweet cherries.

Liu YB · 2025 · Journal of economic entomology

Controlled atmosphere with ultralow oxygen (ULO) treatments were conducted to determine effects against eggs and larvae of spotted wing drosophila, Drosophila suzukii (Diptera: Drosophilidae), in blueberries and cherries at 3 °C in 19…

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Negative / Null Result ReportMedicine

Administration of EAPCI patient video animation versus standard patient information leaflets in the catheterization laboratory: Impact on patient experience assessed using the PATCATH questionnaire.

Rai H, Byrne KK, O'Callaghan D et al. · 2026 · Cardiovascular revascularization medicine : including molecular interventions

Background The Patient Experience in the Catheterization Laboratory (PATCATH) Questionnaire was developed by the European Association of Percutaneous Cardiovascular Intervention (EAPCI) to evaluate patient understanding of coronary…

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Negative / Null Result ReportMedicine

Cavernous ganglioneuroma of the thoracic spine: surgical nuances and outcomes following limited anterior resection.

Yılmaz MC, Tezer P, Olgaç G et al. · 2026 · European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society

Background Spinal tumors constitute approximately 15% of all primary central nervous system neoplasms, with extradural tumors accounting for the majority. Ganglioneuromas are rare, benign tumors of neural crest origin, most often located…

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Negative / Null Result ReportMedicine

Dry Needling Plus Manual Therapy and Exercise for Subacromial Pain Syndrome: A Sham-Controlled Randomized Clinical Trial.

Hando BR, Rhon DI, Barker D et al. · 2026 · The Journal of orthopaedic and sports physical therapy

OBJECTIVE: To determine the effect on Shoulder Pain and Disability Index (SPADI) scores of adding dry needling to a program of exercise and manual therapy in individuals with subacromial pain syndrome (SAPS). DESIGN: Three-arm randomized…

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Negative / Null Result ReportMedicine

Harvesting of peroneus longus tendon autograft

Liang C, He J · 2025 · Journal of Visualized Experiments

Autografts are always used in anterior cruciate ligament (ACL) reconstruction. Traditional sources, such as hamstring tendons, bone-patellar tendon-bone, and quadriceps tendon, are popular choices but may result in muscle imbalances and…

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Negative / Null Result Report

Clavipectoral fascia block associated with intermediate cervical plexus block versus intermediate cervical plexus block alone in clavicle surgeries: a randomized clinical trial

Conceicao D, Helayel P, Garcia J et al. · 2025 · Preprint

Abstract Background: Midshaft clavicular fractures account for approximately 5% of bone fractures. Surgical correction is often necessary to ensure adequate functional recovery. There is no consensus in the literature on which Regional…

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Negative / Null Result ReportMedicine

Effect of Local Cold Application on Nausea and Vomiting in Early Postoperative Period-A Randomized Controlled Trial.

Türkiş NA, Taşdemir N · 2026 · Journal of perianesthesia nursing : official journal of the American Society of PeriAnesthesia Nurses

Purpose Postoperative nausea and vomiting (PONV) is one of the most common complications in surgical patients during the first 24 hours after general anesthesia. This research aimed to evaluate the effect of cold application on early PONV…

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Negative / Null Result ReportMedicine

Cytogenotoxic effects of polycyclic aromatic hydrocarbons complex mixture in human peripheral blood, lung A549 and liver HepG2 cells: Translation of a real-scenario exposure to in vitro.

Kazensky L, Lovrić Štefiček MJ, Kašuba V et al. · 2026 · Environmental research

Polycyclic aromatic hydrocarbons (PAHs) are ubiquitous air pollutants, where their genotoxic potential raises significant public health concerns. This study evaluated the cytotoxic and genotoxic effects of an environmentally relevant…

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Negative / Null Result ReportMedicine

Verification of the protective effect of transfecting brain-derived neurotrophic factor and B-cell lymphoma 2 genes on retina ganglion cells in a rat model of optic nerve injury.

Zhao Z, Fang Y, Xu G et al. · 2026 · Drug discoveries & therapeutics

This pilot study investigated the protective effect of transfecting brain-derived neurotrophic factor (BDNF) and B-cell lymphoma 2 (bcl-2) genes in retinal ganglion cells (RGCs) using in vivo electroporation in an adult rat optic nerve…

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