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19,906 real negative results, null findings, and replication failures · Negative / Null Result Report. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result ReportMedicine

Oral Health Status and Utilization of Dental Services Among Adults With Disability Compared to Those Without Disabilities in Nevada, United States.

Benson, Gomez, DerAshodian et al. · 2026 · Special care in dentistry : official publication of the American Association of Hospital Dentists, the Academy of Dentistry for the Handicapped, and the American Society for Geriatric Dentistry

This study examines disability-related disparities in tooth loss and dental visits, and Medicaid dental service utilization across Nevada counties in 2022. A cross-sectional analysis of the 2022 Behavioral Risk Factor Surveillance System…

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Negative / Null Result ReportMedicine

Consensus-Level and Cluster-Adjusted Evaluation of a Large Language Model for Diagnostic Extraction from Musculoskeletal Radiology Reports.

Bosbach, Montazeri, Senge et al. · 2026 · Diagnostics (Basel, Switzerland)

Purpose: Large language models (LLMs) may reduce administrative workload in radiology by automating structured diagnostic extraction from text reports. This study evaluates the accuracy of ChatGPT-4.0 when extracting correct diagnoses from…

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Negative / Null Result ReportMedicine

Impact of Body Mass Index on Clinical Outcomes of LLETZ.

Paternostro, Joura, Postl et al. · 2026 · Journal of clinical medicine

Background/Objectives: Large loop excision of the transformation zone (LLETZ) is used as a standard treatment for cervical dysplasia. Although obesity is associated with reduced cervical screening participation and may complicate…

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Negative / Null Result ReportMedicine

Efficacy of High Flow Nasal Cannula in Reducing Hypoxemia in Children Undergoing Elective Flexible Fibreoptic Bronchoscopy as Compared to Conventional Low Flow Nasal Cannula: A Randomized Controlled Trial.

Rajvanshi, Kumar, Goyal et al. · 2026 · Pediatric pulmonology

Flexible fibreoptic bronchoscopy (FFB) is widely used in pediatric pulmonology, though hypoxemia remains a primary concern during the procedure. High-flow nasal cannula (HFNC) has shown potential in reducing hypoxemia in adults undergoing…

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Negative / Null Result ReportMedicine

Prospective observational comparative study of radiotherapy induced toxicities (xerostomia, skin reaction, and mucositis) between three-dimensional conformal radiotherapy and intensity modulated radiotherapy technique to oral cavity cancer of head and neck.

Dhakar, Ghori, Parihar et al. · 2026 · The Gulf journal of oncology

Oral cavity cancers often require radiotherapy (RT), leading to toxicities such as xerostomia, skin reactions, and mucositis. This study aims to compare these toxicities between three-dimensional conformal radiotherapy (3D-CRT) and…

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Negative / Null Result ReportMedicine

Comparison of Interferon-Based and Interferon-Free Treatments on the Prognosis of Hepatocellular Carcinoma After Hepatitis C Virus-Sustained Virological Response: A Multicenter Study.

Itoh, Iseda, Yoshizumi et al. · 2026 · Cancer medicine

We examine the impact of interferon (IFN)-based and IFN-free treatment on the prognosis of hepatocellular carcinoma (HCC) after hepatitis C virus (HCV) sustained virological response (SVR). Clinical information was collected on 311 cases…

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Negative / Null Result ReportMedicine

Oral health-related quality of life after early extraction of primary second molars in children with congenitally missing second premolars: a randomized controlled trial with matched controls.

Naoumova, Nawaia, Krekmanova · 2026 · European journal of orthodontics

Extraction of mandibular primary second molars in patients with congenitally missing second premolars may influence oral health-related quality of life (OHRQoL), yet this has not been previously investigated. To assess the impact of…

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Negative / Null Result ReportMedicine

Utility of Postoperative Thyroid Hormone Levels in Predicting the Diagnosis of Adult Growth Hormone Deficiency in Patients Undergoing Surgery for Nonfunctioning Pituitary Neuroendocrine Tumor: A Pilot Study.

Tsujimoto, Yamashiro, Suzuki et al. · 2026 · International journal of endocrinology

Adult growth hormone deficiency (AGHD) is often diagnosed after surgery for nonfunctioning pituitary neuroendocrine tumor (NF-PitNET). While a growth hormone stimulation test (GHST) is required to establish its diagnosis, it is associated…

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Negative / Null Result ReportMedicine

Task Shifting in Cardiac Ablations Compared With Percutaneous Coronary Interventions: The Japanese Circulation Society Chugoku-Shikoku Regional Survey Subanalysis.

Fukue, Suetomi, Matsuura et al. · 2026 · Circulation reports

As part of work-style reform for physicians, task shifting to non-physician healthcare professionals has been promoted in Japan. We previously reported task shifting results for percutaneous coronary interventions (PCI), but the status in…

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Negative / Null Result ReportMedicine

Robotic Mitral Valve Repair in Patients With Thoracic Deformity.

Tomita, Kakuta, Kainuma et al. · 2026 · Circulation reports

Robotic mitral valve repair (MVr) offers superior visualization and dexterity, potentially overcoming challenges in severe thoracic deformity such as pectus excavatum. This study compared surgical outcomes after MVr in patients with and…

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Negative / Null Result ReportMedicine

The Impact of Kidney Donor Profile Index and Human Leukocyte Antigen Mismatch on Graft Survival in Pediatric Kidney Transplant Recipients.

Ranabothu, Smith, Perkins et al. · 2026 · Pediatric transplantation

Pediatric kidney transplant recipients typically receive low-KDPI deceased donor kidneys but often experience higher HLA mismatches. The relationship between KDPI and HLA mismatch and their combined effect on graft and patient outcomes in…

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Negative / Null Result ReportMedicine

Gemcitabine-Based versus Fluoropyrimidine-Based Chemotherapy and Role of Platinum Combination for First-Line Palliative Systemic Treatment in Advanced Ampullary Adenocarcinoma.

Wonglhow, Wetwittayakhlang, Sunpaweravong et al. · 2026 · Cancer management and research

Ampullary adenocarcinoma is a rare malignancy with limited evidence on the efficacy of systemic chemotherapy for advanced disease. This study aimed to evaluate the treatment outcomes of gemcitabine- and fluoropyrimidine-based regimens and…

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Negative / Null Result ReportMedicine

Immediate placement of intrauterine device after second-trimester medical abortion-Secondary outcomes with one-year follow-up.

Hogmark, Westermark, Envall et al. · 2026 · Acta obstetricia et gynecologica Scandinavica

Intrauterine devices (IUDs) effectively prevent unwanted pregnancies. Little is known about long-term outcomes of women choosing an IUD after second-trimester medical abortion. We performed a 12-month follow-up of a multicenter randomized…

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Negative / Null Result ReportMedicine

The impact of leaflet resection versus leaflet preservation on left ventricular reverse remodelling after mitral valve repair: insights from the UK mini mitral trial.

Rao, Bayliss, Wagnild et al. · 2026 · Journal of cardiothoracic surgery

Mitral valve repair (MVr) promotes left ventricular (LV) reverse remodelling, and subsequent reduction in LV diameters and volumes. The effectiveness of different MVr techniques, Resect (leaflet resection) and Respect (leaflet…

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Negative / Null Result ReportMedicine

Field diagnostic performance of the Sysmex XN31 automated hematology analyser for malaria screening among febrile children in a sentinel site for malaria surveillance site in Libreville, Gabon.

Chesly, Patrick, Bedrich et al. · 2026 · International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases

To evaluate the diagnostic performance of the Sysmex XN-31 haematology analyser for malaria detection in a sentinel site. A prospective diagnostic assessment study was conducted among febrile children under 15 years of age, attending a…

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Negative / Null Result ReportMedicine

Revision rate and postoperative volume development of chronic subdural hematomas after burr hole craniotomy in combination with tranexamic acid vs. surgery alone - a single-center propensity score-matched analysis.

Scheer, Witte, Guenzerodt et al. · 2026 · BMC neurology

Chronic subdural hematoma (cSDH) is a common intracranial hemorrhage in elderly patients and is associated with substantial postoperative recurrence rates. Tranexamic acid (TXA) has been proposed as an adjuvant therapy to reduce recurrence…

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Negative / Null Result ReportMedicine

Cryoprecipitate utilization in the neonatal intensive care unit: a single-center review.

Stoeckel, Soule-Albridge, Feldman et al. · 2026 · Journal of perinatology : official journal of the California Perinatal Association

Significant variability exists in the indications for and dosing of cryoprecipitate transfusions. We examined cryoprecipitate transfusions in neonates with a focus on indications, dosing, and the incidence of multi-donor exposure. In this…

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