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20,261 real negative results, null findings, and replication failures · Negative / Null Result Report. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result ReportOpen accessMedicine

Does Pain Self-efficacy influence Initial Forward Bending in Adults with Chronic Low Back Pain following Exercise? A Cohort Study.

McManus F, Pranata A, Simpson JA et al. · 2025 · International journal of sports physical therapy

Background/purpose Chronic low back pain affects how individuals bend. Whether pain self-efficacy, a term describing one's confidence in their ability to perform activities despite experiencing pain, affects how much people with chronic…

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Negative / Null Result ReportOpen accessMedicine

Woody seeds and seedlings are unresponsive to herbivore kairomones.

Headrick KC, Pellegrini BA, Santiago EM et al. · 2026 · AoB PLANTS

Herbivory is particularly threatening to young plants that lack the resources needed to survive an attack. Seeds and seedlings should thus benefit greatly from using pre-attack cues to induce defence before damage. Locomotion mucus from…

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Negative / Null Result ReportOpen accessMedicine

Does civilian oversight impact police legitimacy?

Schiff KJ, Schiff DS, Moy BJ et al. · 2025 · PNAS nexus

Does the implementation of external oversight in policing improve public perceptions of police legitimacy? Civilian review boards (CRBs) are frequently promoted as mechanisms to enhance the legitimacy of police agencies by providing…

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Negative / Null Result ReportOpen accessMedicine

Infants Do Not Reliably Track When Bilingual Speakers Switch Languages.

Potter CE, Lew-Williams C · 2025 · Behavioral sciences (Basel, Switzerland)

It is a widely held belief that bilingual infants benefit from hearing each of their languages spoken by different people, as speakers could serve as a cue for separating the two languages. However, it is not yet known whether infants…

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Negative / Null Result ReportOpen accessMedicine

PCSK9 and Breast Cancer Survival: A Mendelian Randomization Study.

Pott J, Mason AM, Salo V et al. · 2026 · Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology

Background Proprotein convertase subtilisin/kexin type 9 (PCSK9) affects lipid metabolism. A recent study identified an association between rs562556 within the PCSK9 gene and breast cancer survival (BCS), suggesting PCSK9 inhibition as an…

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Negative / Null Result ReportOpen access

PCSK9 and breast cancer survival: a Mendelian Randomization study

Pott J, Mason A, Salo V et al. · 2025 · Preprint

Background Proprotein convertase subtilisin/kexin type 9 (PCSK9) is well known for its causal effects on the lipid metabolism. A recent study identified an association between rs562556 within PCSK9 and breast cancer survival (BCS). It was…

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Negative / Null Result ReportOpen accessMedicine

Vibration-Induced Nystagmus in Patients with Ménière's Disease: Is There a Correlation to Endolymphatic Hydrops?

Lorente-Piera J, Blanco M, Manrique-Huarte R et al. · 2025 · Audiology research

Background/Objectives : Skull vibration-induced nystagmus (SVIN) is a rapid bedside test that reveals vestibular asymmetry. Its clinical utility in Ménière's disease (MD) remains controversial, particularly regarding its association with…

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Negative / Null Result ReportOpen accessMedicine

Outcomes and experiences of music workshops for adolescents with depression and anxiety: An exploratory noncontrolled trial in Bogotá.

Gómez-Restrepo C, Roldan MC, Ariza-Salazar K et al. · 2024 · BMC research notes

Objective Adolescents frequently experience mental distress. However, there is little research on community activities that help adolescents recover from depression and anxiety. This study investigated the outcomes and experiences of music…

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Negative / Null Result ReportOpen accessMedicine

Micronutrient Powders Combined With Malaria Chemoprevention to Improve Anaemia and Cognitive Function in Early Childhood in Mali: A Cluster-Randomised Trial.

Diarra NH, Dicko Y, Roschnik N et al. · 2025 · Maternal & child nutrition

A cluster-randomised controlled trial was conducted in 60 communities in southern Mali to evaluate the impact of micronutrient powders (MNP) combined with seasonal malaria chemoprevention (SMC) on anaemia (primary endpoint), Plasmodium…

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Negative / Null Result ReportMedicine

Challenges in studying the interplay of genes and environment. A study of childhood financial distress moderating genetic predisposition for peak smoking.

Bierut L, Biroli P, Galama TJ et al. · 2023 · Journal Of Economic Psychology

Smoking is one of the leading causes of preventable disease and death in the U.S., and it is strongly influenced both by genetic predisposition and childhood adversity. Using polygenic indices (PGIs) of predisposition to smoking, we…

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Negative / Null Result ReportOpen accessMedicine

Sensory sensitivity and visual discomfort are not associated with altered gamma oscillations: A test of the excitation-inhibition hypothesis.

Sumner P, Powell G, Price A et al. · 2026 · Imaging neuroscience (Cambridge, Mass.)

Many people experience aversive hypersensitivity (discomfort/visual stress) to stimuli such as bright lights, striped patterns, strobing, motion, or complex visual scenes such as supermarkets. Such sensory hypersensitivity is often…

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Negative / Null Result ReportMedicine

Weight cycling and cancer risk in the Sister Study.

Stevens VL, Priest J, Wilkerson J et al. · 2026 · American journal of epidemiology

Weight cycling, when weight is repeatedly lost intentionally and then regained, may perturb biological processes that could influence cancer development. However, results from epidemiologic studies of weight cycling are mixed and provide…

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Negative / Null Result ReportMedicine

The impact of recreational cannabis retailer allocation on emergency department visits: A natural experiment utilizing lottery design.

Bai Y, Cao P, Kim C et al. · 2025 · The International journal on drug policy

Background In October 2018, Canada legalized recreational cannabis, with Ontario distributing retailer licenses through a lottery system in 2019. This study investigates the impact of recreational cannabis retailer allocation on emergency…

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