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Browse the failure-mode index

20,261 real negative results, null findings, and replication failures · Negative / Null Result Report. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result Report

Class Composition Effects in Achievement and Interest and the Role of the Learning Environment Revisited: A Conceptual Replication and Extension of Lavrijsen et al. (2022)

Kopatz M, Wagner W, Neuendorf C et al. · 2026 · Preprint

Class composition is a key contextual factor in students’ academic development. Prior research has mainly focused on class mean achievement, yet less is known about other composition characteristics, possible differences for students with…

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Negative / Null Result ReportMedicine

Ethnic-racial socialization and sociopolitical development among emerging adult college students of color.

Berkley S, Hoyt LT, Zeiders KH et al. · 2026 · Journal of research on adolescence : the official journal of the Society for Research on Adolescence

This study used multilevel growth modeling to examine associations between ethnic-racial socialization (ERS) and sociopolitical development among undergraduates of color (N = 125) attending predominantly White institutions during the 2016…

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Negative / Null Result ReportMedicine

Performance validity tests in a large racially and linguistically diverse pediatric and young adult clinical sample: Investigations of the TOMM, MVP, and MSVT.

MacAllister WS, Désiré N, Brooks BL · 2026 · The Clinical neuropsychologist

Objective There is strong support for the use of performance validity tests (PVTs) in all neuropsychological evaluations, however, research examining racial, ethnic, and linguistic differences in failure rates remains scarce, particularly…

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Negative / Null Result ReportMedicine

Longitudinal Associations Among Avoidant/Restrictive Food Intake Disorder Symptoms, Body Dissatisfaction, Restriction, and Suicide Ideation Among Adolescents.

Sahlan RN, Frietchen R, Billman Miller MG et al. · 2025 · Suicide & life-threatening behavior

Objective Although previous research has established bidirectional links between many eating disorder (ED) symptoms and suicidal ideation (SI), no research has examined how symptoms of avoidant/restrictive food intake disorder (ARFID)…

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Negative / Null Result ReportMedicine

Feasibility of the pre-operative measurement of fractional exhaled nitric oxide and respiratory mechanics to predict respiratory outcomes in children undergoing general anaesthesia.

Hauser N, Sommerfield D, Nguyen J et al. · 2026 · Anaesthesia

Introduction Peri-operative respiratory adverse events remain a major cause of morbidity and mortality in children undergoing general anaesthesia; those with asthma are at higher risk. The aim of this feasibility study was to determine…

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Negative / Null Result ReportMedicine

Death Conceptualizations: How do Youth Presenting to a Pediatric Psychiatric Emergency Department View the End of their Lives?

Tezanos KM, Simeone A, Gerson R et al. · 2026 · Child psychiatry and human development

Youth are presenting to Emergency Departments (EDs) following a suicide-related crisis at higher rates and younger ages. Clinicians lack tools to effectively discern suicide risk in younger patients. The present investigation examines how…

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Negative / Null Result ReportMedicine

Prenatal echocardiographic diagnosis and outcomes of fetal sustained supraventricular tachycardia: a ten-year single-center experience.

Ciriello GD, Colonna D, Morelli C et al. · 2026 · Indian pacing and electrophysiology journal

Fetal echocardiography plays a pivotal role in the diagnosis and management of fetal arrhythmias, allowing evaluation of the electrophysiological mechanism and guiding appropriate medical therapy. Herein, we describe our ten-year…

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Negative / Null Result ReportMedicine

The interdependence of health and grandparenting intensity: A dyadic perspective from grandparent couples in the Health and Retirement Study.

Chan ACY, Stephan AT, Sneed RS · 2026 · The journals of gerontology. Series B, Psychological sciences and social sciences

Objectives While the intensity of grandparent caregiving has been linked to older adults' health, limited research has examined the bidirectional associations between grandparenting intensity and health, particularly within grandparent…

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Negative / Null Result ReportMedicine

Prediction of Anthracycline Benefit in Hormone Receptor-Positive, Human Epidermal Growth Factor Receptor 2-Negative Early-Stage Breast Cancer by the MammaPrint 70-Gene Signature for Patients Enrolled in the FLEX Study.

O'Shaughnessy J, Brufsky AM, Layeequr Rahman R et al. · 2026 · JCO precision oncology

Purpose Randomized trials have not demonstrated clear benefit from anthracyclines for patients with hormone receptor-positive, human epidermal growth factor receptor 2-negative (HER2-) early breast cancer (EBC). The MammaPrint 70-gene…

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Negative / Null Result ReportMedicine

Longitudinal associations of cardiorespiratory fitness and physical activity with changes in cognitive function in breast cancer patients undergoing chemotherapy: a prospective matched-control study.

Xiao H, Warner E, Ryan J et al. · 2026 · Cancer causes & control : CCC

Purpose Cancer-related cognitive impairment (CRCI) is a common concern among breast cancer (BC) patients receiving chemotherapy, yet predictors of short-term cognitive change remain unclear. This study examined whether baseline…

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Negative / Null Result ReportMedicine

Trauma-focused or non-trauma-focused? Treatment preferences and expectancies among veterans with co-occurring posttraumatic stress disorder and substance use disorder.

Alpert E, Kaplan A, Nelson D et al. · 2026 · Psychological trauma : theory, research, practice and policy

Objective Among patients with co-occurring posttraumatic stress disorder (PTSD) and substance use disorders (SUDs), little is known about early PTSD treatment processes, including treatment preference and outcome expectancy. This study…

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Negative / Null Result ReportMedicine

Kidney Transplantation for Lithium Nephrotoxicity is Associated With Noninferior Graft and Patient Survival: A National Donor-Stratified Registry Analysis.

Cohen H, Toro D, Zuluaga D et al. · 2026 · Clinical transplantation

Introduction To evaluate donor-stratified graft and patient survival following kidney transplantation (KT) for lithium-associated end-stage kidney disease (ESKD). Methods This retrospective analysis utilized the Organ Procurement and…

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Negative / Null Result ReportOpen accessMedicine

Predictive Factors of Augmented Reality-Based Clinical Task Performance Among Novice Users: Cross-Sectional Quantitative Study.

Vellore AJ, Bhatia S, Kann MR et al. · 2026 · JMIR XR and spatial computing

Background Augmented reality (AR) can provide risk-free training for medical trainees, yet little is known about which learner characteristics facilitate adoption or inform training design. Objective We aimed to identify which learner…

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Negative / Null Result ReportMedicine

Breaking the PROMISE: poor association between brain volume loss and clinical disability worsening over 2 years of follow-up in primary progressive multiple sclerosis.

Koch M, Mostert J, Strijbis EM et al. · 2026 · Journal of neurology, neurosurgery, and psychiatry

Background Phase 2 clinical trials in primary progressive multiple sclerosis (PPMS) often use MRI brain volume measures as their primary endpoint. Here, we investigate the longitudinal association between change in MRI outcomes and change…

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