20,261 real negative results, null findings, and replication failures · Negative / Null Result Report. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Parkhoo K, Schmitz LA, Fröb L et al. · 2026 · Dentistry journal
Objectives : Six dentin adhesives were tested in vitro regarding their cytotoxicity toward human fibroblasts. AdheSE, Clearfil SE Bond, Hybrid Bond, One-up Bond F Plus, Optibond Solo Plus, and Syntac were tested using a cell culture model.…
View details →Korodimos N, Wojtyś ME, Kostopanagiotou K et al. · 2026 · Journal of clinical medicine
Background: Non-small-cell lung cancer (NSCLC) is driven by distinct oncogenic alterations with important therapeutic and prognostic implications. Noninvasive biomarkers that predict molecular status in surgically resectable disease may…
View details →Mahajan A, Haideri S, Kumar VVH et al. · 2026 · Journal of education and health promotion
Background The oral health is an integral part of general well-being in children suffering from attention deficit hyperactivity disorder (ADHD). The present study aimed to analyze the impact of oral health education program on children…
View details →Abdi A, Abbasi E, Abazarlou A · 2026 · BMC neurology
Objectives Migraine is a common and disabling neurological disorder in children, often requiring preventive treatment. This study aimed to compare the efficacy and tolerability of cinnarizine and topiramate in the prophylaxis of migraine…
View details →Peker N, Yücetürk A, Tığlı E et al. · 2026 · Journal of ovarian research
Background We aimed to evaluate whether delayed initiation of gonadotropin hormone-releasing hormone (GnRH) antagonist treatment affects premature ovulation and the number of good-quality blastocysts. We retrospectively reviewed the…
View details →Yan Z, Jiang Q, Lu Z et al. · 2026 · International journal of general medicine
Background Intervertebral disc degeneration (IVDD) is a major cause of low back pain. Observational studies suggest a link with gut microbiota (GM), possibly mediated by systemic inflammation, but causality remains unclear. Objective To…
View details →Conde-Disla E, González-Olmo MJ, Olmos-Valverde M et al. · 2026 · Dentistry journal
Background: Pain during orthodontic debonding is a common clinical concern. Although previous studies have mainly focused on mechanical approaches to reduce discomfort, the influence of emotional characteristics of patients on pain…
View details →Xu X, Zhang B, Wang X et al. · 2026 · Orthopaedic surgery
Objective There is no consensus on the age restriction for total ankle arthroplasty (TAA) patients. The aim of our study was to analyze the clinical function, radiographic outcomes, patient satisfaction, and complications between patients…
View details →Agarwal P, Kumar P, Chugh VK et al. · 2026 · Cureus
Background and aim Postoperative pain following root canal treatment (RCT) can be influenced by the obturation technique, as variations in apical sealing and material extrusion may affect periapical tissue response. The aim of this study…
View details →Lopresti AL, Smith SJ, Ferdinands FR · 2026 · Frontiers in reproductive health
Background Khaya senegalensis is a tree species that has traditional use for the alleviation of menstrual and hormonal symptoms in women. Moreover, supplementation with a Khaya senegalensis preparation (Khapregesic®) was associated with…
View details →Mousa N, Hasan AK · 2026 · Cureus
Background This study aimed to evaluate nasal morphological characteristics and their relationship with vertical facial growth patterns in a Syrian adult population using lateral cephalometric analysis. Methodology This retrospective…
View details →Atsuta S, Koizumi S, Takahashi SS et al. · 2026 · Dentistry journal
Background/Objectives : Acceleration of orthodontic tooth movement remains a major challenge in clinical orthodontics. Evidence suggests that increased local blood flow around the alveolar bone is key to bone remodeling and potentially…
View details →Pei Y, Jones L, Minga J · 2026 · American journal of speech-language pathology
Purpose This study investigated patterns of question use in conversation among individuals with traumatic brain injury (TBI) by analyzing the frequency, types, and social actions of the questions. Method Questions from conversational…
View details →Çam Ö, Ateş MO, Keleş A · 2026 · BMC oral health
BACKGROUND: The aim of this study was to evaluate the association of buccolingual width (BLW), age, and gender with the detection of a lingual canal in mandibular anterior teeth using cone-beam computed tomography (CBCT). METHODS: CBCT…
View details →Mohammed ABAERAAK, Abdallah AM · 2026 · Preprint
Abstract Background: The thyroid gland is a vital endocrine organ responsible for the secretion of triiodothyronine (T3) and thyroxine (T4), hormones that regulate metabolism, growth, and tissue development. Thyroid dysfunction, including…
View details →Szablewska AW, Zając B · 2026 · Scientific reports
Gestational diabetes mellitus (GDM) is associated with various perinatal complications and may affect neonatal acid-base status. Umbilical cord arterial blood gas (ABG) analysis provides an objective measure of fetal well-being at birth,…
View details →Mohamed NS, Abdel Aziz NAS · 2026 · Cutaneous and ocular toxicology
Purpose To quantitatively assess the macular microvasculature after intravenous chemotherapy (IVC) for retinoblastoma (RB) using optical coherence tomography angiography (OCTA). Methods A case control study compared the OCT and OCTA…
View details →Soenarti S, Sitorus S, Nugroho MB et al. · 2026 · Rehabilitacion
Sarcopenia represents a leading cause of functional decline in older adults. This randomized controlled trial examined whether the addition of ankle weights to a Nordic walking protocol yields superior outcomes compared with standard…
View details →Bader S, Magnuson A, Brorsson C et al. · 2026 · European journal of trauma and emergency surgery : official publication of the European Trauma Society
Background Haemorrhagic shock (HS) is frequently associated with secondary cerebral injury due to compromised cerebral perfusion. Resuscitative endovascular balloon occlusion of the aorta (REBOA) is an effective haemorrhage control…
View details →Iyiol AR · 2026 · Cureus
Background Intestinal ischemia-reperfusion (I/R) injury represents a critical clinical condition characterized by oxidative stress, inflammatory activation, and impairment of intestinal mucosal integrity. Although restoration of blood flow…
View details →Mizushima Y, Whaley C, Kaimal A et al. · 2026 · JAMA network open
Importance Noneconomic damage caps, a form of medical malpractice law, remain controversial, as several states have enacted such laws since 2010, whereas others have repealed them. The clinical consequences of repealing these caps are…
View details →Longo UG, Mazzola A, Stelitano G et al. · 2026 · Clinical journal of sport medicine : official journal of the Canadian Academy of Sport Medicine
Objective The aim of this study was to evaluate, in runners participating in the 2019 Rome Marathon, the interaction between resilience and coping and how they are influenced by sex, age, body weight, height, number of weekly training…
View details →Eke H, Toprak B, Bozkurt ED · 2026 · Journal of cardiothoracic surgery
BACKGROUND: Laryngoscopy and intubation provoke strong sympathetic activation and may cause hemodynamic instability in cardiovascular surgery patients. Maintaining adequate hypnotic depth and cerebral oxygenation during induction is…
View details →Kotian RN, Ajoy SM, Panduranga R et al. · 2026 · The bone & joint journal
Aims There are conflicting results in the literature regarding the safety of the peroneus longus tendon (PLT) as a potential graft for anterior cruciate ligament (ACL) reconstruction, and no long-term studies with objective assessment…
View details →Tankuş M, Memikoğlu TUT · 2026 · BMC oral health
Background This study aimed to investigate enamel surface changes after debonding of teeth with metal and ceramic brackets exhibiting varying severities of white spot lesions (WSLs). Methods Forty healthy premolars were divided into two…
View details →Chereji G, Chelaru VF, Nicoară SD · 2026 · Diagnostics (Basel, Switzerland)
Background/Objectives : Rhegmatogenous retinal detachment (RRD) is a surgical emergency that causes vision loss if not properly treated. Pars plana vitrectomy (PPV) is the preferred procedure for most complex RRD cases, with a high success…
View details →Wang Z, Zhang Y, Zhang K et al. · 2026 · Experimental and therapeutic medicine
Within the present study, the aim was to investigate the dynamic changes in iron metabolism parameters in patients with ST-segment elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (PCI) and to…
View details →Liu J, Liu M, Xu Y et al. · 2026 · Clinics (Sao Paulo, Brazil)
Background BOS172722, a selective TTK inhibitor, shows promise for Breast Cancer (BC) treatment. The role of gut microbiota as a potential mediator in this process has not been established. This Mendelian Randomization (MR) study…
View details →Algahefi AL, Alhammadi MS, Li Z et al. · 2026 · American journal of otolaryngology
Purpose To evaluate three-dimensional changes in the maxillary sinus (MS) and pharyngeal airway space (PAS) following rapid (RME), slow (SME), and magnetic maxillary expansion (MME) using cone-beam computed tomography (CBCT). Methods This…
View details →Darup A, Ettinger M, Savov P et al. · 2026 · Archives of orthopaedic and trauma surgery
Introduction Periprosthetic joint infection (PJI) represents a severe complication following total hip arthroplasty (THA) and total knee arthroplasty (TKA). The intraarticular application of vancomycin powder is increasingly integrated…
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